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1دورية أكاديمية
المؤلفون: Gabriela Ispas, Anil Koul, Johan Verbeeck, Jennifer Sheehan, Brigitte Sanders-Beer, Dirk Roymans, Koen Andries, Marie-Claude Rouan, Sandra De Jonghe, Jean-François Bonfanti, Marc Vanstockem, Kenneth Simmen, Rene Verloes
المصدر: PLoS ONE, Vol 10, Iss 5, p e0126959 (2015)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1932-6203
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2
المؤلفون: Sandy Thijssen, Sofie Starckx, Adriana Looszova, Geert Mannens, Ilham Smyej, Sandra De Jonghe, Tom Verhaeghe, Marie-Claude Rouan, Ann Lampo
المصدر: Toxicologic pathology. 45(5)
مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, medicine.drug_class, Metabolite, 030106 microbiology, Antibiotics, Antitubercular Agents, Administration, Oral, Pharmacology, Toxicology, Pathology and Forensic Medicine, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Pharmacokinetics, Internal medicine, medicine, Animals, Tissue Distribution, Diarylquinolines, Adverse effect, Muscle, Skeletal, Molecular Biology, Pancreas, Phospholipids, Phospholipidosis, business.industry, Stomach, Myocardium, Cell Biology, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, chemistry, Toxicity, Female, Bedaquiline, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925cefd774175f9c4f8da214b2717b26
https://pubmed.ncbi.nlm.nih.gov/28789609 -
3
المؤلفون: Maxwell D. Cummings, Tse-I Lin, Lili Hu, Abdellah Tahri, David McGowan, Katie Amssoms, Stefaan Last, Benoit Devogelaere, Marie-Claude Rouan, Leen Vijgen, Jan Martin Berke, Pascale Dehertogh, Els Fransen, Erna Cleiren, Liesbet van der Helm, Gregory Fanning, Origène Nyanguile, Kenny Simmen, Pieter Van Remoortere, Pierre Raboisson, Sandrine Vendeville
المصدر: Journal of Medicinal Chemistry. 57:1880-1892
مصطلحات موضوعية: Models, Molecular, Simeprevir, Magnetic Resonance Spectroscopy, Hepatitis C virus, Drug Evaluation, Preclinical, Viral Nonstructural Proteins, Crystallography, X-Ray, medicine.disease_cause, Antiviral Agents, Heterocyclic Compounds, 4 or More Rings, Mass Spectrometry, Virus, Structure-Activity Relationship, In vivo, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Potency, Enzyme Inhibitors, Polymerase, Sulfonamides, biology, Chemistry, Virology, In vitro, Rats, biology.protein, Molecular Medicine
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4
المؤلفون: Wim Bert Griet Schepens, Judith Eva Baumeister, Tim H. M. Jonckers, Geerwin Yvonne Paul Haché, Sabine Hallenberger, Marie-Claude Rouan, Jennifer C. Sasaki
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:4998-5002
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Pharmacokinetics, Amide, Drug Discovery, medicine, Animals, Cytochrome P-450 CYP3A, Humans, HIV Protease Inhibitor, Benzothiazoles, Molecular Biology, ADME, Benzoxazoles, CYP3A4, Organic Chemistry, HIV Protease Inhibitors, Benzoxazole, Amides, Rats, chemistry, Benzothiazole, HIV-1, Cytochrome P-450 CYP3A Inhibitors, Molecular Medicine, Ritonavir, Caco-2 Cells, Half-Life, medicine.drug
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5
المؤلفون: Sandrine Vendeville, Tse-I. Lin, Lili Hu, Abdellah Tahri, David McGowan, Maxwell D. Cummings, Katie Amssoms, Maxime Canard, Stefaan Last, Iris Van den Steen, Benoit Devogelaere, Marie-Claude Rouan, Leen Vijgen, Jan Martin Berke, Pascale Dehertogh, Els Fransen, Erna Cleiren, Liesbet van der Helm, Gregory Fanning, Kristof Van Emelen, Origène Nyanguile, Kenny Simmen, Pierre Raboisson
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:4437-4443
مصطلحات موضوعية: Indoles, Macrocyclic Compounds, Stereochemistry, Hepatitis C virus, Clinical Biochemistry, Allosteric regulation, Drug Evaluation, Preclinical, Pharmaceutical Science, Hepacivirus, Viral Nonstructural Proteins, Virus Replication, Ring (chemistry), medicine.disease_cause, Antiviral Agents, Heterocyclic Compounds, 4 or More Rings, Biochemistry, Rats, Sprague-Dawley, Structure-Activity Relationship, Allosteric Regulation, Pharmacokinetics, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Potency, Enzyme Inhibitors, Molecular Biology, Indole test, Sulfonamides, Chemistry, Organic Chemistry, Rats, Liver, Cell culture, Molecular Medicine
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6
المؤلفون: Ron Gilissen, Lieve Dillen, Tom Gevers, Nancer Lounis, Araz Raoof, Koen Andries, Marie-Claude Rouan
المصدر: Antimicrobial agents and chemotherapy
مصطلحات موضوعية: Male, Metabolite, Antitubercular Agents, Colony Count, Microbial, Microbial Sensitivity Tests, Pharmacology, Drug Administration Schedule, Mycobacterium tuberculosis, Mice, chemistry.chemical_compound, Bacterial Proteins, Pharmacokinetics, Oral administration, Animals, Humans, Medicine, Drug Dosage Calculations, Pharmacology (medical), Dosing, Diarylquinolines, Lung, Tuberculosis, Pulmonary, Biotransformation, biology, business.industry, Pharmacology. Therapy, Drug Administration Routes, Half-life, Desmethyl, biology.organism_classification, ATP Synthetase Complexes, Disease Models, Animal, Infectious Diseases, chemistry, Area Under Curve, Pharmacodynamics, Quinolines, Female, business, Half-Life
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218a2580892f26d9ce1c8f2e48a60e85
https://doi.org/10.1128/aac.00720-11 -
7
المؤلفون: D Sawant, Dirk Roymans, R. Verloes, Koen Andries, P Sowinski, B Wang, Anil Koul, Marc Vanstockem, B Van Kerckhove, D Nauwelaers, Marie-Claude Rouan, Peter J. M. Openshaw, F Van Velsen, M De Meulder, P Van Remoortere, C Schnoeller, Wieslawa Olszewska, G Ispas, Jean-François Bonfanti, T Van de Casteele
المصدر: European Respiratory Journal. 38:401-408
مصطلحات موضوعية: Lung Diseases, Pulmonary and Respiratory Medicine, Palivizumab, Pyridines, medicine.drug_class, Respiratory Syncytial Virus Infections, Virus Replication, Antiviral Agents, Mice, chemistry.chemical_compound, In vivo, medicine, Animals, Mononegavirales, Lung, Mice, Inbred BALB C, medicine.diagnostic_test, biology, business.industry, Ribavirin, Viral Load, Virus Internalization, biology.organism_classification, medicine.disease, Virology, Respiratory Syncytial Viruses, Treatment Outcome, Bronchoalveolar lavage, chemistry, Bronchiolitis, Immunology, Benzimidazoles, Female, Antiviral drug, business, Bronchoalveolar Lavage Fluid, Viral load, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86870442d480a236e604b1db14574811
https://doi.org/10.1183/09031936.00005610 -
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المؤلفون: Guy Van den Mooter, Liesbeth Grooten, Gerben Albert Eleutherius Van 'T Klooster, Elke Van Gyseghem, Jan Rosier, Laurent Schueller, Herman de Kock, Marie-Claude Rouan, Lieven Baert, Voorspoels Jody Firmin Marceline, Pieter Van Remoortere
المصدر: European Journal of Pharmaceutical Sciences. 41:193-200
مصطلحات موضوعية: Sulfonamides, Chromatography, Chemistry, Pharmaceutical, Sodium lauryl sulphate, Pharmaceutical Science, HIV Protease Inhibitors, Polyethylene glycol, Pharmacology, chemistry.chemical_compound, Dogs, Pharmacokinetics, Pharmaceutical technology, chemistry, Drug delivery, Plasma concentration, medicine, Animals, Darunavir, Tablets, medicine.drug, Co administration
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المؤلفون: Daniele Alberti, Romain Sechaud, Renzo Galanello, Antonio Piga, Hilde Bigler, Marie-Claude Rouan
المصدر: The Journal of Clinical Pharmacology. 43:565-572
مصطلحات موضوعية: Pharmacology, business.industry, Deferasirox, Cmax, Pharmacokinetics, Tolerability, Oral administration, Pharmacodynamics, Blood plasma, Toxicity, Immunology, Medicine, Pharmacology (medical), business, medicine.drug
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10
المؤلفون: David McGowan, Sandrine Vendeville, Tse-I Lin, Abdellah Tahri, Lili Hu, Maxwell D. Cummings, Katie Amssoms, Jan Martin Berke, Maxime Canard, Erna Cleiren, Pascale Dehertogh, Stefaan Last, Els Fransen, Elisabeth Van Der Helm, Iris Van den Steen, Leen Vijgen, Marie-Claude Rouan, Gregory Fanning, Origène Nyanguile, Kristof Van Emelen, Kenneth Simmen, Pierre Raboisson
المصدر: Bioorganicmedicinal chemistry letters. 22(13)
مصطلحات موضوعية: Indoles, Stereochemistry, Clinical Biochemistry, Allosteric regulation, Drug Evaluation, Preclinical, Pharmaceutical Science, Hepacivirus, Viral Nonstructural Proteins, Ring (chemistry), Virus Replication, Biochemistry, Antiviral Agents, Ns5b polymerase, Rats, Sprague-Dawley, chemistry.chemical_compound, Structure-Activity Relationship, Allosteric Regulation, Cell Line, Tumor, Drug Discovery, Structure–activity relationship, Potency, Animals, Humans, Enzyme Inhibitors, Molecular Biology, Cell potency, Indole test, Chemistry, Organic Chemistry, Rats, Microsomes, Liver, Molecular Medicine, Bioisostere