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المؤلفون: Winslow EH, Marino LB

المصدر: AJN American Journal of Nursing; 1975 Apr, Vol. 75, p586-591, 6p

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المؤلفون: de Souza PC; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil., Fernandes GFS; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Department of Drugs and Medicines, Araraquara, São Paulo, 14800-903, Brazil., Marino LB; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil., Ribeiro CM; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil., Silva PBD; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Department of Drugs and Medicines, Araraquara, São Paulo, 14800-903, Brazil., Chorilli M; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Department of Drugs and Medicines, Araraquara, São Paulo, 14800-903, Brazil., Silva CSP; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil., Resende FA; Department of Biological Sciences and Health, UNIARA - University of Araraquara, Araraquara, São Paulo, 14801-340, Brazil., Solcia MC; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil., de Grandis RA; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil; Department of Biological Sciences and Health, UNIARA - University of Araraquara, Araraquara, São Paulo, 14801-340, Brazil., Costa CAS; São Paulo State University (UNESP), School of Odontology, Department of Physiology and Pathology, Araraquara, São Paulo, 14801-903, Brazil., Cho SH; Institute of Tuberculosis Research, UIC - University of Illinois at Chicago, Chicago, Illinois, 60612-7231, USA., Wang Y; Institute of Tuberculosis Research, UIC - University of Illinois at Chicago, Chicago, Illinois, 60612-7231, USA., Franzblau SG; Institute of Tuberculosis Research, UIC - University of Illinois at Chicago, Chicago, Illinois, 60612-7231, USA., Dos Santos JL; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Department of Drugs and Medicines, Araraquara, São Paulo, 14800-903, Brazil., Pavan FR; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil. Electronic address: fernando.pavan@unesp.br.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Oct; Vol. 130, pp. 110592. Date of Electronic Publication: 2020 Aug 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Antitubercular Agents/*therapeutic use , Oxadiazoles/*therapeutic use , Tuberculosis/*drug therapy, Animals ; Antitubercular Agents/pharmacology ; Antitubercular Agents/toxicity ; Bacteria/drug effects ; Drug Resistance, Bacterial ; Female ; Mice ; Mice, Inbred BALB C ; Microbial Sensitivity Tests ; Mutagenicity Tests ; Mycobacterium tuberculosis/drug effects ; Oxadiazoles/pharmacology ; Oxadiazoles/toxicity ; Tuberculosis/microbiology

المؤلفون: El-Wahab HAAA; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff CF10 3NB, Wales, UK; Department of Medicinal Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt., Accietto M; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff CF10 3NB, Wales, UK; Department of Life Sciences, University of Modena and Reggio Emilia, Via G. Campi 183, 41125 Modena, Italy., Marino LB; Faculty of Pharmaceutical Sciences, UNESP - Univ Estadual Paulista, Araraquara, São Paulo 14801-902, Brazil., McLean KJ; Manchester Institute of Biotechnology, School of Chemistry, University of Manchester, Manchester M1 7DN, UK., Levy CW; Manchester Institute of Biotechnology, School of Chemistry, University of Manchester, Manchester M1 7DN, UK., Abdel-Rahman HM; Department of Medicinal Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt., El-Gendy MA; Department of Medicinal Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt., Munro AW; Manchester Institute of Biotechnology, School of Chemistry, University of Manchester, Manchester M1 7DN, UK., Aboraia AS; Department of Medicinal Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt., Simons C; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff CF10 3NB, Wales, UK. Electronic address: simonsc@cardiff.ac.uk.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2018 Jan 01; Vol. 26 (1), pp. 161-176. Date of Electronic Publication: 2017 Nov 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Antitubercular Agents/*pharmacology , Azoles/*pharmacology , Dipeptides/*pharmacology , Mycobacterium tuberculosis/*drug effects , Peptides, Cyclic/*pharmacology , Piperazines/*pharmacology, Antitubercular Agents/chemical synthesis ; Antitubercular Agents/chemistry ; Azoles/chemistry ; Binding Sites/drug effects ; Cytochrome P-450 Enzyme System/chemistry ; Cytochrome P-450 Enzyme System/metabolism ; Dipeptides/chemistry ; Dose-Response Relationship, Drug ; Ligands ; Microbial Sensitivity Tests ; Models, Molecular ; Molecular Structure ; Mycobacterium tuberculosis/metabolism ; Peptides, Cyclic/chemistry ; Piperazine ; Piperazines/chemistry ; Structure-Activity Relationship

المؤلفون: Taban IM; School of Pharmacy & Pharmaceutical Sciences, Cardiff University , King Edward VII Avenue, Cardiff CF10 3NB, U.K., Elshihawy HEAE; Department of Organic Chemistry, Faculty of Pharmacy, Suez Canal University , Ismalia, Egypt., Torun B; School of Pharmacy & Pharmaceutical Sciences, Cardiff University , King Edward VII Avenue, Cardiff CF10 3NB, U.K.; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Ankara University , 06100 Tandogan, Ankara, Turkey., Zucchini B; School of Pharmacy & Pharmaceutical Sciences, Cardiff University , King Edward VII Avenue, Cardiff CF10 3NB, U.K.; Department of Pharmaceutical Sciences, University of Perugia , Via del Liceo, 1-06123 Perugia, Italy., Williamson CJ; School of Pharmacy & Pharmaceutical Sciences, Cardiff University , King Edward VII Avenue, Cardiff CF10 3NB, U.K., Altuwairigi D; School of Pharmacy & Pharmaceutical Sciences, Cardiff University , King Edward VII Avenue, Cardiff CF10 3NB, U.K., Ngu AST; School of Pharmacy & Pharmaceutical Sciences, Cardiff University , King Edward VII Avenue, Cardiff CF10 3NB, U.K., McLean KJ; Manchester Institute of Biotechnology, School of Chemistry, The University of Manchester , 131 Princess Street, Manchester M1 7DN, U.K., Levy CW; Manchester Institute of Biotechnology, School of Chemistry, The University of Manchester , 131 Princess Street, Manchester M1 7DN, U.K., Sood S; Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute , 1 Midland Road, London NW1 1AT, U.K., Marino LB; Faculty of Pharmaceutical Sciences, UNESP-Univ Estadual Paulista , Araraquara, São Paulo14801-902, Brazil., Munro AW; Manchester Institute of Biotechnology, School of Chemistry, The University of Manchester , 131 Princess Street, Manchester M1 7DN, U.K., de Carvalho LPS; Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute , 1 Midland Road, London NW1 1AT, U.K., Simons C; School of Pharmacy & Pharmaceutical Sciences, Cardiff University , King Edward VII Avenue, Cardiff CF10 3NB, U.K.

المصدر: Journal of medicinal chemistry [J Med Chem] 2017 Dec 28; Vol. 60 (24), pp. 10257-10267. Date of Electronic Publication: 2017 Dec 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 Enzyme Inhibitors/*chemistry , Cytochrome P-450 Enzyme Inhibitors/*pharmacology , Cytochrome P-450 Enzyme System/*chemistry , Mycobacterium tuberculosis/*drug effects , Small Molecule Libraries/*chemistry, Antitubercular Agents/chemistry ; Antitubercular Agents/pharmacology ; Bacterial Proteins/antagonists & inhibitors ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Binding Sites ; Crystallography, X-Ray ; Cytochrome P-450 Enzyme Inhibitors/chemical synthesis ; Cytochrome P-450 Enzyme System/metabolism ; Drug Evaluation, Preclinical/methods ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Pyrazoles/chemistry ; Small Molecule Libraries/pharmacology ; Spectrophotometry, Ultraviolet

المؤلفون: Dos Santos Fernandes GF; São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.; São Paulo State University (UNESP) , School of Pharmaceutical Sciences, Araraquara 14800903, Brazil.; Universidad de Navarra , Department of Organic and Pharmaceutical Chemistry, Instituto de Salud Tropical, Pamplona 31008, Spain., de Souza PC; São Paulo State University (UNESP) , School of Pharmaceutical Sciences, Araraquara 14800903, Brazil.; Institute of Tuberculosis Research, University of Illinois at Chicago , Chicago, Illinois 60607, United States., Moreno-Viguri E; Universidad de Navarra , Department of Organic and Pharmaceutical Chemistry, Instituto de Salud Tropical, Pamplona 31008, Spain., Santivañez-Veliz M; Universidad de Navarra , Department of Organic and Pharmaceutical Chemistry, Instituto de Salud Tropical, Pamplona 31008, Spain., Paucar R; Universidad de Navarra , Department of Organic and Pharmaceutical Chemistry, Instituto de Salud Tropical, Pamplona 31008, Spain., Pérez-Silanes S; Universidad de Navarra , Department of Organic and Pharmaceutical Chemistry, Instituto de Salud Tropical, Pamplona 31008, Spain., Chegaev K; Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino , Turin 10124, Italy., Guglielmo S; Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino , Turin 10124, Italy., Lazzarato L; Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino , Turin 10124, Italy., Fruttero R; Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino , Turin 10124, Italy., Man Chin C; São Paulo State University (UNESP) , School of Pharmaceutical Sciences, Araraquara 14800903, Brazil., da Silva PB; São Paulo State University (UNESP) , School of Pharmaceutical Sciences, Araraquara 14800903, Brazil., Chorilli M; São Paulo State University (UNESP) , School of Pharmaceutical Sciences, Araraquara 14800903, Brazil., Solcia MC; São Paulo State University (UNESP) , School of Pharmaceutical Sciences, Araraquara 14800903, Brazil., Ribeiro CM; São Paulo State University (UNESP) , School of Pharmaceutical Sciences, Araraquara 14800903, Brazil., Silva CSP; São Paulo State University (UNESP) , School of Pharmaceutical Sciences, Araraquara 14800903, Brazil., Marino LB; São Paulo State University (UNESP) , School of Pharmaceutical Sciences, Araraquara 14800903, Brazil., Bosquesi PL; São Paulo State University (UNESP) , School of Pharmaceutical Sciences, Araraquara 14800903, Brazil., Hunt DM; Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute , 1 Midland Road, London NW1 1AT, United Kingdom., de Carvalho LPS; Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute , 1 Midland Road, London NW1 1AT, United Kingdom., de Souza Costa CA; São Paulo State University (UNESP) , School of Odontology, Araraquara 14801903, Brazil., Cho SH; Institute of Tuberculosis Research, University of Illinois at Chicago , Chicago, Illinois 60607, United States., Wang Y; Institute of Tuberculosis Research, University of Illinois at Chicago , Chicago, Illinois 60607, United States., Franzblau SG; Institute of Tuberculosis Research, University of Illinois at Chicago , Chicago, Illinois 60607, United States., Pavan FR; São Paulo State University (UNESP) , School of Pharmaceutical Sciences, Araraquara 14800903, Brazil., Dos Santos JL; São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.; São Paulo State University (UNESP) , School of Pharmaceutical Sciences, Araraquara 14800903, Brazil.

المصدر: Journal of medicinal chemistry [J Med Chem] 2017 Oct 26; Vol. 60 (20), pp. 8647-8660. Date of Electronic Publication: 2017 Oct 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antitubercular Agents/*chemistry , Antitubercular Agents/*pharmacology , Heterocyclic Compounds/*chemistry , Heterocyclic Compounds/*pharmacology, Animals ; Antitubercular Agents/chemical synthesis ; Antitubercular Agents/pharmacokinetics ; Biological Availability ; Caco-2 Cells ; Heterocyclic Compounds/chemical synthesis ; Heterocyclic Compounds/pharmacokinetics ; Humans ; Mice ; Mice, Inbred BALB C ; Microbial Sensitivity Tests ; Mycobacterium tuberculosis/drug effects ; Oxides/chemistry ; Spectrum Analysis/methods

المؤلفون: Fernandes GFDS; School of Pharmaceutical Sciences, UNESP - Univ Estadual Paulista, Araraquara, 14800903, Brazil., de Souza PC; School of Pharmaceutical Sciences, UNESP - Univ Estadual Paulista, Araraquara, 14800903, Brazil., Marino LB; School of Pharmaceutical Sciences, UNESP - Univ Estadual Paulista, Araraquara, 14800903, Brazil., Chegaev K; Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Turin, 10124, Italy., Guglielmo S; Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Turin, 10124, Italy., Lazzarato L; Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Turin, 10124, Italy., Fruttero R; Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Turin, 10124, Italy., Chung MC; School of Pharmaceutical Sciences, UNESP - Univ Estadual Paulista, Araraquara, 14800903, Brazil., Pavan FR; School of Pharmaceutical Sciences, UNESP - Univ Estadual Paulista, Araraquara, 14800903, Brazil., Dos Santos JL; School of Pharmaceutical Sciences, UNESP - Univ Estadual Paulista, Araraquara, 14800903, Brazil. Electronic address: santosjl@fcfar.unesp.br.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2016 Nov 10; Vol. 123, pp. 523-531. Date of Electronic Publication: 2016 Jul 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antitubercular Agents/*chemical synthesis , Antitubercular Agents/*pharmacology , Mycobacterium tuberculosis/*drug effects , Oxadiazoles/*chemical synthesis , Oxadiazoles/*pharmacology, Antitubercular Agents/chemistry ; Antitubercular Agents/toxicity ; Cell Line, Tumor ; Chemistry Techniques, Synthetic ; Drug Design ; Humans ; Oxadiazoles/chemistry ; Oxadiazoles/toxicity

المؤلفون: Larrouy-Maumus G; Mycobacterial Metabolism and Antibiotic Research Laboratory and Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute, Mill Hill Laboratory, London NW7 1AA, United Kingdom; Laboratory of Chemical Biology of Tuberculosis Pathogenesis, MRC Centre for Molecular Bacteriology and Infection, Imperial College London, Kensington, London SW7 2DD, United Kingdom., Marino LB; Mycobacterial Metabolism and Antibiotic Research Laboratory and Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute, Mill Hill Laboratory, London NW7 1AA, United Kingdom; School of Pharmaceutical Sciences, São Paulo State University (UNESP), 4801-902 Araraquara, SP, Brazil., Madduri AV; Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School , Boston, Massachusetts 02115, United States., Ragan TJ; Mycobacterial Metabolism and Antibiotic Research Laboratory and Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute , Mill Hill Laboratory, London NW7 1AA, United Kingdom., Hunt DM; Mycobacterial Metabolism and Antibiotic Research Laboratory and Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute , Mill Hill Laboratory, London NW7 1AA, United Kingdom., Bassano L; Laboratory of Chemical Biology of Tuberculosis Pathogenesis, MRC Centre for Molecular Bacteriology and Infection, Imperial College London , Kensington, London SW7 2DD, United Kingdom., Gutierrez MG; Mycobacterial Metabolism and Antibiotic Research Laboratory and Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute , Mill Hill Laboratory, London NW7 1AA, United Kingdom., Moody DB; Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School , Boston, Massachusetts 02115, United States., Pavan FR; School of Pharmaceutical Sciences, São Paulo State University (UNESP) , 4801-902 Araraquara, SP, Brazil., de Carvalho LP; Mycobacterial Metabolism and Antibiotic Research Laboratory and Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute , Mill Hill Laboratory, London NW7 1AA, United Kingdom.

المصدر: ACS infectious diseases [ACS Infect Dis] 2016 May 13; Vol. 2 (5), pp. 352-360. Date of Electronic Publication: 2016 Mar 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2373-8227 (Print) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: PubMed not MEDLINE