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المؤلفون: Dorothee Dormann, Mario Hofweber, Imke Baade, Ralph H. Kehlenbach, Saskia Hutten, Erin L. Sternburg, Marius Pörschke
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, FTD, frontotemporal dementia, RNA-binding protein, importins, RG/RGG motifs, Nuclear Localization Signals, Receptors, Cytoplasmic and Nuclear, Biochemistry, T, tyrosine, PY, proline–tyrosine, R, arginine, TNPO, transportin, Chemistry, NTR, nuclear transport receptor, LCD, low-complexity domain, TB, transport buffer, beta Karyopherins, EGFP, enhanced green fluorescent protein, Cell biology, LLPS, liquid–liquid phase separation, Transportin 1, RBP, RNA-binding protein, transportin, RGG3, arginine–glycine–rich, Research Article, Protein Binding, rps, ribosomal proteins, SEC, size-exclusion chromatography, Importin, nuclear transport, Karyopherins, unme, unmethylated, PRMT1, protein arginine N-methyltransferase 1, 03 medical and health sciences, Stress granule, S, supernatant, Ribosomal protein, CIRBP, cold-inducible RNA-binding protein, Humans, Molecular Biology, Xpo 4, exportin 4, CRM1, chromosome region maintenance 1, Cell Nucleus, 030102 biochemistry & molecular biology, Cell Biology, SG, stress granule, TNPO3, transportin-3, TNPO1, transportin-1, 030104 developmental biology, MBP, maltose binding protein, NLS, nuclear localization signal, RNA-Binding Protein FUS, BSA, bovine serum albumin, Nuclear transport, phase separation, TDP-43, TAR DNA-binding protein 43, RS, arginine–serine, fused in sarcoma (FUS), Nuclear localization sequence, TNPO2, transportin-2, DAPI, 4′,6-diamidino-2-phenylindole, FUS, fused in sarcoma, HeLa Cells, Molecular Chaperones
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30987084425aae85f9e9ab0bd8b3bb2e
http://europepmc.org/articles/PMC8131929 -
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المؤلفون: Dorothee Dormann, James Shorter, Francesca Simonetti, Marian Hruska-Plochan, Sinem Usluer, Hana M. Odeh, Charlotte M. Fare, Tobias Madl, Dieter Edbauer, Mario Hofweber, Magdalini Polymenidou, Mareike Czuppa, Benjamin Bourgeois, Saskia Hutten
المساهمون: University of Zurich, Hutten, Saskia, Dormann, Dorothee
المصدر: Cell reports
Cell reports 33(12), 108538 (2020). doi:10.1016/j.celrep.2020.108538مصطلحات موضوعية: 0301 basic medicine, nuclear transport receptor, Arginine, TDP-43, metabolism [Arginine], Receptors, Cytoplasmic and Nuclear, 610 Medicine & health, Genetics and Molecular Biology, Importin, environment and public health, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, TDP, C9orf72, 1300 General Biochemistry, Genetics and Molecular Biology, importin, nuclear import receptor, Humans, chaperone, ddc:610, Receptor, phase separation, dipeptide repeat proteins, biology, Chemistry, metabolism [Dipeptides], FTD, nneurodegeneration, Dipeptides, In vitro, Cell biology, 030104 developmental biology, Cytoplasm, Chaperone (protein), General Biochemistry, biology.protein, Nuclear transport, ALS, metabolism [Receptors, Cytoplasmic and Nuclear], 11493 Department of Quantitative Biomedicine, 030217 neurology & neurosurgery
وصف الملف: 2020_Hutten_Polymenidou_etal_CellReports.pdf - application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f215b36a8bdac9b075423fd7758cb8
https://www.zora.uzh.ch/id/eprint/197563/ -
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المؤلفون: Benjamin, Bourgeois, Saskia, Hutten, Benjamin, Gottschalk, Mario, Hofweber, Gesa, Richter, Julia, Sternat, Claudia, Abou-Ajram, Christoph, Göbl, Gerd, Leitinger, Wolfgang F, Graier, Dorothee, Dormann, Tobias, Madl
المصدر: Proceedings of the National Academy of Sciences of the United States of America
مصطلحات موضوعية: Cell Nucleus, Cytoplasm, Protein Conformation, Nuclear Localization Signals, Active Transport, Cell Nucleus, Glycine, RNA-Binding Proteins, Transportin-1, Biological Sciences, Transportin-3, Arginine, beta Karyopherins, environment and public health, nuclear import, Peptide Fragments, Biophysics and Computational Biology, CIRBP, Serine, Humans, Tyrosine, phase separation, HeLa Cells, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::55babdae476c197dad1248790d15a3ba
https://pubmed.ncbi.nlm.nih.gov/32234784 -
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المؤلفون: Tobias Madl, Mario Hofweber, Emil Spreitzer, Dierk Niessing, Annika Niedner-Boblenz, Benjamin Bourgeois, Mikael Simons, Saskia Hutten, Martina Schifferer, Dorothee Dormann, Marc-David Ruepp
المصدر: Cell 173, 706-719.e13 (2018)
Hofweber, M, Hutten, S, Bourgeois, B, Spreitzer, E, Niedner-Boblenz, A, Schifferer, M, Ruepp, M-D, Simons, M, Niessing, D, Madl, T & Dormann, D 2018, ' Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation ', Cell, vol. 173, no. 3, pp. 706-719.e13 . https://doi.org/10.1016/j.cell.2018.03.004
Cell 173(3), 706-719.e13 (2018). doi:10.1016/j.cell.2018.03.004مصطلحات موضوعية: 0301 basic medicine, Cytoplasm, Magnetic Resonance Spectroscopy, Arginine, Amino Acid Motifs, chemistry [Arginine], metabolism [Neurodegenerative Diseases], chemistry [Molecular Chaperones], chemistry [RNA-Binding Protein FUS], hemic and lymphatic diseases, Homeostasis, chemistry [beta Karyopherins], Karyopherin, chemistry.chemical_classification, Neurodegeneration, Neurodegenerative Diseases, Methylation, beta Karyopherins, Cell biology, Protein Binding, DNA, Complementary, Active Transport, Cell Nucleus, TNPO1 protein, human, Biology, Karyopherins, metabolism [DNA, Complementary], General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Stress granule, Protein Domains, medicine, NLS, Humans, ddc:610, Als, Ftd, Karyopherin-β2 (kapβ2), Transportin (tnpo1), Arginine Methylation, Fused In Sarcoma (fus), Nuclear Import, Phase Separation, Stress Granules, metabolism [Cytoplasm], chemistry [Karyopherins], FUS protein, human, DNA Methylation, medicine.disease, metabolism [Frontotemporal Lobar Degeneration], 030104 developmental biology, chemistry, Mutation, RNA-Binding Protein FUS, Nuclear transport, Frontotemporal Lobar Degeneration, Nuclear localization sequence, Densitometry, HeLa Cells, Molecular Chaperones
وصف الملف: application/pdf
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المؤلفون: Massimiliano Manzo, Pascaline Rombaut, Yolanda Markaki, Christina Bauer, Sebastian Bultmann, Martha Smets, Katharina Thanisch, Elisabeth Schmidtmann, Christopher B. Mulholland, Susanne Leidescher, Elisabeth Kremmer, Heinrich Leonhardt, Franz Herzog, Weihua Qin, Mario Hofweber
المصدر: Nucleic Acids Research
Nucleic Acids Res. 43:e112 (2015)مصطلحات موضوعية: Cellular differentiation, Gene Expression, Computational biology, medicine.disease_cause, Genome, Protein–protein interaction, Genome engineering, Cell Line, Genetics, medicine, Animals, Gene, Cell Engineering, Embryonic Stem Cells, Recombination, Genetic, Mutation, biology, Integrases, Antibodies, Monoclonal, Cell Differentiation, Genomics, Isogenic human disease models, Integrase, Rats, Genetic Loci, biology.protein, Methods Online, CRISPR-Cas Systems
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c00f827d947581ebab419a759351d1
https://pubmed.ncbi.nlm.nih.gov/26007658
