المؤلفون: Baranca Buijsers, Marjolein Garsen, Mark de Graaf, Marinka Bakker-van Bebber, Chunming Guo, Xue Li, Johan van der Vlag

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: heparanase-1, heparanase-2, endothelial glycocalyx degradation, proteinuria, glomerulonephritis, diabetic nephropathy, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1098184/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/a7517a03f86d40e8a0e1cafc4440f22e

المؤلفون: Marjolein Garsen, Baranca Buijsers, Marloes Sol, Lena Gockeln, Ramon Sonneveld, Toin H. van Kuppevelt, Mark de Graaf, Jacob van den Born, Jan A.A.M. Kamps, Daniël H. van Raalte, Rutger W. van der Meer, Hildo J. Lamb, Jan-Luuk Hillebrands, Ton J. Rabelink, Marissa L. Maciej-Hulme, Guido Krenning, Tom Nijenhuis, Johan van der Vlag

المصدر: EBioMedicine, Vol 90, Iss , Pp 104506- (2023)

مصطلحات موضوعية: Peroxisome proliferator-activated receptor ɣ, Heparanase, Proteinuria, Thiazolidinediones, Glomerular endothelial cells, Podocytes, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396423000713; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/13deeeb23f314fa5bfa8672de7b2f11d

المؤلفون: Marjolein Garsen, Angelique L Rops, Jinhua Li, Katrien van Beneden, Christiane van den Branden, Jo Hm Berden, Ton J Rabelink, Johan van der Vlag

المصدر: PLoS ONE, Vol 11, Iss 8, p e0160894 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4978400?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/481a9cdddd304ca2b2fd5399ff13b96c

المؤلفون: Marjolein Garsen, Maaike Steenhof, Alex Zwiers

المصدر: Therapeutic Innovation & Regulatory Science

مصطلحات موضوعية: Antineoplastic Agents, Drug development, Pharmacy, Marketing authorization, Orphan drug, 03 medical and health sciences, 0302 clinical medicine, EMA, Agency (sociology), Global health, Humans, media_common.cataloged_instance, Pharmacology (medical), Operations management, European Union, Conditional marketing authorization, European union, Drug Approval, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Original Research, Cancer, 030304 developmental biology, media_common, Marketing, 0303 health sciences, Accelerated assessment, business.industry, Public Health, Environmental and Occupational Health, Authorization, Timeline, Scientific advice, 030220 oncology & carcinogenesis, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d247d3b2f02386fdb5219af293b7dd59
https://doi.org/10.1007/s43441-021-00260-5

المؤلفون: Alex Zwiers, Marjolein Garsen, Grace Omes-Smit

المصدر: Therapeutic Innovation & Regulatory Science

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Pharmacy, Antineoplastic Agents, Drug development, Marketing authorization, medicine.disease_cause, Pharmacotherapy, Clinical trials, Internal medicine, Healthy volunteers, medicine, Humans, Pharmacology (medical), Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Original Research, Clinical Trials as Topic, business.industry, Public Health, Environmental and Occupational Health, Clinical trial, Genotoxicity testing, Genetic toxicology, business, Genotoxicity, Genetic Toxicology, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3774eb7ac9a84989643b1cde5007bf
https://pubmed.ncbi.nlm.nih.gov/34379306

المؤلفون: Markus A. Loeven, Markus H. Hoffmann, Julia M. Hofstra, Elmar Pieterse, Marjolein Garsen, Olivier W H van der Heijden, Hanneke K Knaapen, Johan van der Vlag, Nils Rother, Jo H. M. Berden, Luuk B. Hilbrands, Simon C. Satchell

المصدر: Arteriosclerosis, Thrombosis, and Vascular Biology, 37, 7, pp. 1371-1379
Arteriosclerosis, Thrombosis, and Vascular Biology, 37, 1371-1379

مصطلحات موضوعية: 0301 basic medicine, Adult, Extracellular Traps, Mice, Inbred MRL lpr, Epithelial-Mesenchymal Transition, Time Factors, Endothelium, Neutrophils, Kidney Glomerulus, Receptor for Advanced Glycation End Products, Vascular permeability, Biology, Cell junction, Severity of Illness Index, Capillary Permeability, 03 medical and health sciences, Young Adult, Phagocytosis, Antigens, CD, medicine, Extracellular, Human Umbilical Vein Endothelial Cells, Animals, Humans, Epithelial–mesenchymal transition, beta Catenin, Elastase, Neutrophil extracellular traps, Cadherins, Lupus Nephritis, Clathrin, Endocytosis, Cell biology, Disease Models, Animal, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], 030104 developmental biology, medicine.anatomical_structure, Immunology, Inflammatory diseases Radboud Institute for Health Sciences [Radboudumc 5], Mice, Inbred CBA, Renal disorders Radboud Institute for Health Sciences [Radboudumc 11], Cardiology and Cardiovascular Medicine, Leukocyte Elastase, Inflammatory diseases Radboud Institute for Molecular Life Sciences [Radboudumc 5], Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78ff252ffde8eb0b724ad0f55a27217
https://hdl.handle.net/2066/174782

المؤلفون: Angelique L.W.M.M. Rops, Joost G. J. Hoenderop, Tom Nijenhuis, Marjolein Garsen, Jo H. M. Berden, Ramon Sonneveld, Toin H. van Kuppevelt, Johan van der Vlag, Ton J. Rabelink, Suzanne Huntink

المصدر: The Journal of Pathology. 237:472-481

مصطلحات موضوعية: medicine.medical_specialty, Proteinuria, urogenital system, Chemistry, Glomerular basement membrane, urologic and male genital diseases, medicine.disease, Calcitriol receptor, female genital diseases and pregnancy complications, Pathology and Forensic Medicine, Podocyte, Diabetic nephropathy, medicine.anatomical_structure, Endocrinology, Internal medicine, medicine, Glomerular Filtration Barrier, Vitamin D and neurology, Heparanase, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f068162e601456ab51211130289f089d
https://doi.org/10.1002/path.4593

المؤلفون: Marjolein Garsen, Ganqi Wang, Michael Elkin, Johan van der Vlag, Ton J. Rabelink, Bernard M. van den Berg

المصدر: Nature Reviews. Nephrology, 13, 4, pp. 201-212
Nature Reviews Nephrology, 13(4), 201-212
Nature Reviews. Nephrology, 13, 201-212

مصطلحات موضوعية: 0301 basic medicine, Cell signaling, Cell Survival, Cell, Biology, Extracellular matrix, 03 medical and health sciences, chemistry.chemical_compound, medicine, Animals, Humans, Heparanase, Glucuronidase, Autophagy, Heparan sulfate, medicine.disease, Extracellular Matrix, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], chemistry, Nephrology, Immunology, Glomerular Filtration Barrier, Kidney Diseases, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801c2374ed65a10a4a45240a34d9ca81
https://hdl.handle.net/1887/95108

المؤلفون: Johan van der Vlag, Olivia Lenoir, Marjolein Garsen, Henry B.P.M. Dijkman, Ton J. Rabelink, Angelique L.W.M.M. Rops, Brigith Willemsen, Jo H. M. Berden, Pierre-Louis Tharaux, Toin H. van Kuppevelt

المصدر: Journal of the American Society of Nephrology, 27, 3545-3551
Journal of the American Society of Nephrology, 27(12), 3545-3551
Journal of the American Society of Nephrology, 27, 12, pp. 3545-3551

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Kidney Glomerulus, Biology, Glycocalyx, Podocyte, Diabetic nephropathy, Endothelial activation, Mice, 03 medical and health sciences, Internal medicine, medicine, Animals, Diabetic Nephropathies, Heparanase, Glucuronidase, Endothelin-1, Podocytes, General Medicine, medicine.disease, Endothelin 1, Proteinuria, Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10], Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Nephrology, Glomerular Filtration Barrier, Brief Communications, Endothelin receptor

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679e1b3947f4dc126d71ef9ec6b9b2e7
https://doi.org/10.1681/asn.2015091070

المؤلفون: Thomas Reinheckel, Brigith Willemsen, Johan van der Vlag, Ton J. Rabelink, Angelique L.W.M.M. Rops, Toin H. van Kuppevelt, Marjolein Garsen, Jo H. M. Berden, Frans G. M. Russel, Henry B.P.M. Dijkman

المصدر: Kidney International. Supplement, 90, 1012-1022
Kidney International. Supplement, 90, 5, pp. 1012-1022
Kidney International, 90(5), 1012-1022

مصطلحات موضوعية: 0301 basic medicine, Dynamins, medicine.medical_specialty, Cathepsin L, 030232 urology & nephrology, glomerulus, urologic and male genital diseases, Podocyte, Diabetes Mellitus, Experimental, Diabetic nephropathy, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Animals, Heparanase, Diabetic Nephropathies, Adaptor Proteins, Signal Transducing, Glucuronidase, Cathepsin, Proteinuria, biology, business.industry, diabetic nephropathy, Microfilament Proteins, medicine.disease, Mice, Inbred C57BL, Cytoskeletal Proteins, Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10], Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Nephrology, biology.protein, Albuminuria, Synaptopodin, medicine.symptom, proteinuria, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6587c616302a762ab593a32fd1993218
https://doi.org/10.1016/j.kint.2016.06.035