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المؤلفون: Chiang J. Li, David S. Leggett, Magdi M. Moussa, Jason Hill, Mark A. Ashwell, Dennis S. France, Chang-Rung Chen, Youzhi Li, Sébastien Jeay, Neru Munshi
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4ce340728dfa8b147d5d39ba35a58f
https://doi.org/10.1158/1535-7163.22485296 -
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المؤلفون: Chiang J. Li, David S. Leggett, Magdi M. Moussa, Jason Hill, Mark A. Ashwell, Dennis S. France, Chang-Rung Chen, Youzhi Li, Sébastien Jeay, Neru Munshi
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266530d573120c053bc6898e1d8c2b56
https://doi.org/10.1158/1535-7163.c.6531881.v1 -
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المؤلفون: Mark Lawrence Ashwell
المصدر: Journal of Financial Crime. 24:393-411
مصطلحات موضوعية: 021103 operations research, Exploit, Intelligence analysis, business.industry, 05 social sciences, Big data, 0211 other engineering and technologies, Digital transformation, Information technology, 02 engineering and technology, Data science, Competitive advantage, Interconnectedness, 0502 economics and business, Social media, Sociology, business, Law, General Economics, Econometrics and Finance, 050203 business & management
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المؤلفون: Mark A. Ashwell, Jean-Marc Lapierre, Christopher Brassard, Karen Bresciano, Cathy Bull, Susan Cornell-Kennon, Sudharshan Eathiraj, Dennis S. France, Terence Hall, Jason Hill, Eoin Kelleher, Sampada Khanapurkar, Darin Kizer, Steffi Koerner, Jeff Link, Yanbin Liu, Sapna Makhija, Magdi Moussa, Nivedita Namdev, Khanh Nguyen, Robert Nicewonger, Rocio Palma, Jeff Szwaya, Manish Tandon, Uma Uppalapati, David Vensel, Laurie P. Volak, Erika Volckova, Neil Westlund, Hui Wu, Rui-Yang Yang, Thomas C. K. Chan
المصدر: Journal of Medicinal Chemistry. 55:5291-5310
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Pyridines, Administration, Oral, Biological Availability, AKT1, Antineoplastic Agents, Plasma protein binding, Pharmacology, Crystallography, X-Ray, Mice, Structure-Activity Relationship, Adenosine Triphosphate, In vivo, Catalytic Domain, Cell Line, Tumor, Drug Discovery, Animals, Humans, Structure–activity relationship, Phosphorylation, Protein kinase B, Adaptor Proteins, Signal Transducing, Cell Proliferation, Effector, Chemistry, Imidazoles, Ribosomal Protein S6 Kinases, 70-kDa, Small molecule, Biochemistry, Microsomes, Liver, Molecular Medicine, Proto-Oncogene Proteins c-akt, Protein Binding
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المؤلفون: Neru Munshi, Sébastien Jeay, Youzhi Li, Chang-Rung Chen, Dennis S. France, Mark A. Ashwell, Jason Hill, Magdi M. Moussa, David S. Leggett, Chiang J. Li
المصدر: Molecular Cancer Therapeutics. 9:1544-1553
مصطلحات موضوعية: Cancer Research, Mice, Nude, Phases of clinical research, Apoptosis, Biology, medicine.disease_cause, Proto-Oncogene Mas, Receptor tyrosine kinase, c-Met inhibitor, Mice, chemistry.chemical_compound, Cell Line, Tumor, Neoplasms, medicine, Animals, Humans, Pyrroles, Phosphorylation, Tivantinib, Protein Kinase Inhibitors, Cell Proliferation, Immunosuppression Therapy, Proto-Oncogene Proteins c-met, Xenograft Model Antitumor Assays, Small molecule, Pyrrolidinones, Oncology, chemistry, Caspases, Quinolines, Cancer research, biology.protein, Growth inhibition, Carcinogenesis, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69d31b4f864065eb6f2b2fde852c2ff
https://doi.org/10.1158/1535-7163.mct-09-1173 -
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المؤلفون: Thomas C.K. Chan, Erika Volckova, Rui-Yang Yang, Caiyun Zhong, Mark A. Ashwell, Xiu-Sheng Miao, Darin Kizer, Yunxia Wang, Ronald E. Savage
المصدر: Rapid Communications in Mass Spectrometry. 23:12-22
مصطلحات موضوعية: Cell type, Metabolite, Glucuronidation, Antineoplastic Agents, Glucuronates, Kidney, Mass Spectrometry, Cryopreservation, Analytical Chemistry, Mice, chemistry.chemical_compound, Dogs, Sulfation, Glucosides, Biotransformation, Animals, Humans, Metabolomics, Cytotoxic T cell, Intestinal Mucosa, Lung, Cells, Cultured, Spectroscopy, Sulfates, Chemistry, Hydrolysis, Organic Chemistry, Metabolism, Rats, Biochemistry, Isotope Labeling, Hepatocytes, Chromatography, Liquid, Naphthoquinones
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المؤلفون: Uma Uppalapati, Mark A. Ashwell, Bin Zhang, Xiubin Gu, David Leggett, Chiang J. Li
المصدر: SLAS Discovery. 13:538-543
مصطلحات موضوعية: Programmed cell death, Indoles, DNA damage, Cell, Cell Cycle Proteins, Protein Serine-Threonine Kinases, Biology, environment and public health, Biochemistry, Analytical Chemistry, Cell Line, Tumor, medicine, Humans, Phosphorylation, RNA, Small Interfering, Coloring Agents, Cytotoxicity, Checkpoint Kinase 2, Fluorescent Dyes, Cell Death, G2-M DNA damage checkpoint, Molecular biology, enzymes and coenzymes (carbohydrates), medicine.anatomical_structure, Fluorescent Antibody Technique, Direct, Cell culture, Enzyme Induction, High-content screening, Trans-Activators, Molecular Medicine, Biological Assay, biological phenomena, cell phenomena, and immunity, DNA Damage, HeLa Cells, Propidium, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16819613f79653412d7fcccae44b09c
https://doi.org/10.1177/1087057108318509 -
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المؤلفون: Rui-Yang Yang, Syed M. Ali, Manish Tandon, Erika Volckova, Ronald E. Savage, Xiu-Sheng Miao, Hui Wu, Mark A. Ashwell, Thomas C.K. Chan, Darin Kizer
المصدر: Bioorganic & Medicinal Chemistry. 16:5635-5643
مصطلحات موضوعية: Erythrocytes, Magnetic Resonance Spectroscopy, Metabolite, Clinical Biochemistry, Pharmaceutical Science, Oxidative phosphorylation, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Drug Discovery, Humans, Molecular Biology, chemistry.chemical_classification, Molecular Structure, Chemistry, Organic Chemistry, Decarbonylation, Stereoisomerism, Metabolism, In vitro, Quinone, Microsomes, Liver, Molecular Medicine, Lactone, Naphthoquinones
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المؤلفون: Hui Wu, Darin Kizer, Ronald E. Savage, Erika Volckova, Xiu-Sheng Miao, Rui-Yang Yang, Mark A. Ashwell, Caiyun Zhong, Thomas C.K. Chan, Xiaoying He, Jeffrey G. Supko, Pengfei Song
المصدر: Drug Metabolism and Disposition. 36:641-648
مصطلحات موضوعية: Pharmacology, Chromatography, Metabolite, Pharmaceutical Science, Haplorhini, Metabolism, Plasma protein binding, Gas Chromatography-Mass Spectrometry, In vitro, Pyrone, Rats, Mice, Metabolic pathway, chemistry.chemical_compound, Dogs, Species Specificity, chemistry, Biochemistry, Pyran, Animals, Humans, Naphthoquinones, Protein Binding, Whole blood
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62245b50c3a4ff50e367a6b94662646
https://doi.org/10.1124/dmd.107.018572 -
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المؤلفون: Ping Ye, Jifeng Liu, Daniel Yohannes, Mark A. Ashwell, Andrew Smellie, Shi-Chung Ng, Chris Wilson, Craig M. Thompsons, Ying Si
المصدر: SLAS Discovery. 11:21-28
مصطلحات موضوعية: Paclitaxel, Mitosis, Biology, Biochemistry, Analytical Chemistry, chemistry.chemical_compound, Tubulin, Cell Line, Tumor, Tumor Cells, Cultured, medicine, Humans, DAPI, Cell Proliferation, Cell growth, Molecular biology, Small molecule, Chromatin, Cell biology, Vinblastine, chemistry, Research Design, Cell culture, High-content screening, Quinazolines, biology.protein, Molecular Medicine, Biological Assay, Drug Screening Assays, Antitumor, DNA, Biotechnology, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f5d0dfbb4a80aa4fe3d19d76f8d926
https://doi.org/10.1177/1087057105280726
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