المؤلفون: Joana Ribeiro, Christopher A. Procyk, Emma L. West, Michelle O’Hara-Wright, Monica F. Martins, Majid Moshtagh Khorasani, Aura Hare, Mark Basche, Milan Fernando, Debbie Goh, Neeraj Jumbo, Matteo Rizzi, Kate Powell, Menahil Tariq, Michel Michaelides, James W.B. Bainbridge, Alexander J. Smith, Rachael A. Pearson, Anai Gonzalez-Cordero, Robin R. Ali

المصدر: Cell Reports, Vol 35, Iss 3, Pp 109022- (2021)

مصطلحات موضوعية: retinal organoid, transplantation, cell therapy, cone photoreceptor, outer segment, rescue, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124721003363; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/f2a1aa9c1fb544b5b5376bb03b90e605

المؤلفون: Robin R. Ali, Anna B. Graca, James W B Bainbridge, Alexander J. Smith, Ayako Matsuyama, Joana Ribeiro, Rachael A. Pearson, Mark Basche, Nozie D. Aghaizu, Aikaterini A Kalargyrou, Anastasios Georgiadis, Claire Hippert

المصدر: Glia. 69:2272-2290

مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, Ependymoglial Cells, Intermediate Filaments, Vimentin, macromolecular substances, Cell morphology, Retina, Glial scar, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Glial Fibrillary Acidic Protein, medicine, Animals, Intermediate filament, biology, Glial fibrillary acidic protein, Retinal Degeneration, Hypertrophy, medicine.disease, Cell biology, 030104 developmental biology, medicine.anatomical_structure, nervous system, Neurology, Gliosis, biology.protein, RNA Interference, sense organs, medicine.symptom, Neuroglia, Muller glia, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d345deb36e380d06c43502d6b5e77d5
https://doi.org/10.1002/glia.24034

المؤلفون: Aikaterini A Kalargyrou, Emma L. West, Alexander J. Smith, Mark Basche, Robin R. Ali, Rachael A. Pearson, Aura Hare

المصدر: EMBO reports. 22

مصطلحات موضوعية: Retina, Gap junction, Retinal, Extracellular vesicle, Biochemistry, Cell biology, Transplantation, chemistry.chemical_compound, medicine.anatomical_structure, nervous system, chemistry, Cytoplasm, Organelle, Genetics, medicine, sense organs, Molecular Biology, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2cc3ad0a73357b1a3fc1b6ead8cffc13
https://doi.org/10.15252/embr.202153732

المؤلفون: Claire Hippert, Anna B. Graca, Mark Basche, Aikaterini A. Kalargyrou, Anastasios Georgiadis, Joana Ribeiro, Ayako Matsuyama, Nozie Aghaizu, James W. Bainbridge, Alexander J. Smith, Robin R. Ali, Rachael A. Pearson

المصدر: Glia. 69

مصطلحات موضوعية: Cellular and Molecular Neuroscience, Neurology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7127684e71e89bc375cc46ae51bf391d
https://doi.org/10.1002/glia.24057

المؤلفون: Matteo Rizzi, Mark Basche, Menahil Tariq, Joana Ribeiro, Michel Michaelides, Majid Moshtagh Khorasani, Neeraj Jumbo, Emma L. West, Rachael A. Pearson, Aura Hare, Anai Gonzalez-Cordero, Monica F. Martins, Alexander J. Smith, Debbie Goh, Michelle O’Hara-Wright, Kate Powell, Christopher A. Procyk, Milan Fernando, Robin R. Ali, James W B Bainbridge

المصدر: Cell Reports
Cell Reports, Vol 35, Iss 3, Pp 109022-(2021)

مصطلحات موضوعية: Male, Retinal Ganglion Cells, 0301 basic medicine, Retinal degeneration, genetic structures, Peripherins, Gene Expression, degeneration, Degeneration (medical), Cell therapy, Mice, 0302 clinical medicine, cone photoreceptor, Biology (General), Induced pluripotent stem cell, Cell Differentiation, Dependovirus, Organoids, medicine.anatomical_structure, Receptors, Glutamate, Retinal ganglion cell, Retinal Cone Photoreceptor Cells, Retinal Bipolar Cells, Protein Kinase C-alpha, macular degeneration, QH301-705.5, Genetic Vectors, Induced Pluripotent Stem Cells, Primary Cell Culture, Transplantation, Heterologous, Mice, Transgenic, Biology, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, visual function, medicine, Animals, Humans, Vision, Ocular, Retina, retinal organoid, Recovery of Function, Mycotoxins, Macular degeneration, electrophysiology, medicine.disease, eye diseases, Transplantation, Disease Models, Animal, 030104 developmental biology, Synapses, outer segment, rescue, sense organs, cell therapy, Neuroscience, Biomarkers, Photic Stimulation, 030217 neurology & neurosurgery, transplantation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7ff1187122a7b66381120016057aff
https://doi.org/10.1016/j.celrep.2021.109022

المؤلفون: Robin R. Ali, Amna Z. Shah, Giulia Massaro, Sara E. Mole, Olha Semenyuk, Ryea Maswood, Michael P. Hughes, Sophia-Martha Kleine Holthaus, Alexander J. Smith, Mark Basche, Saul Herranz-Martin, Justin Hoke, Ahad A. Rahim, Mikel Aristorena, Izabela P Klaska

المصدر: Human molecular genetics. 28(23)

مصطلحات موضوعية: Batten disease, Genetic enhancement, Genetic Vectors, Disease, Biology, Bioinformatics, 03 medical and health sciences, Mice, 0302 clinical medicine, Neuronal Ceroid-Lipofuscinoses, Genetics, medicine, Animals, Humans, Vector (molecular biology), Molecular Biology, Gene, Genetics (clinical), 030304 developmental biology, Injections, Intraventricular, 0303 health sciences, Neurodegeneration, Brain, Membrane Proteins, General Medicine, Genetic Therapy, Dependovirus, medicine.disease, Transmembrane protein, Motor coordination, Disease Models, Animal, Treatment Outcome, Animals, Newborn, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ee98cc75a5fe0d91ad95cb7e646534
https://pubmed.ncbi.nlm.nih.gov/31807779

المؤلفون: D. Frank P. Larkin, Alexander J. Smith, Mark Basche, Satoshi Kawasaki, Matthew J. Branch, Daniel Kampik, Robin R. Ali, Martha Robinson

المصدر: Human gene therapy. 29(10)

مصطلحات موضوعية: 0301 basic medicine, genetic structures, Genetic enhancement, Genetic Vectors, Fluorescent Antibody Technique, Gene Expression, Gene delivery, Viral vector, 03 medical and health sciences, Transduction (genetics), Mice, 0302 clinical medicine, Transduction, Genetic, Genetics, medicine, Animals, Humans, Cell Lineage, Transgenes, Bowman Membrane, Molecular Biology, Corneal epithelium, Recombination, Genetic, biology, business.industry, Stem Cells, Lentivirus, Epithelium, Corneal, Gene Transfer Techniques, Dependovirus, biology.organism_classification, eye diseases, Impaired Vision, Molecular Imaging, 030104 developmental biology, medicine.anatomical_structure, Organ Specificity, 030221 ophthalmology & optometry, Cancer research, Molecular Medicine, Female, sense organs, Stem cell, Injections, Intraocular, business, Injections, Intraperitoneal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b1894df234fb3ab4073ad9bd5e7e06
https://pubmed.ncbi.nlm.nih.gov/30070149

المؤلفون: R. Michael Linden, Els Henckaerts, Rebecca J. Holley, Antonette Bennett, Patrick Aldrin-Kirk, Robin R. Ali, Amir Saam Youshani, Carla Martins, Alexey V. Pshezhetsky, Mavis Agbandje-McKenna, Brian W. Bigger, André S L M Antunes, Thierry Levade, Julie Tordo, Helen Parker, Paul Rouse, Zelpha D'Souza, Larbi Dridi, Kevin B. Stacey, Ahad A. Rahim, Annie Godwin, Nathalie Clement, Claire O'Leary, Daniel M. Davis, Ai Yin Liao, Simon N. Waddington, Nuria Palomar, Mark Basche, Hélène F.E. Gleitz, Adam Dyer, Tomas Björklund

المصدر: Brain
Tordo, J, O'Leary, C, Antunes, A S L M, Palomar, N, Aldrin-Kirk, P, Basche, M, Bennett, A, D'Souza, Z, Gleitz, H, Godwin, A, Holley, R J, Parker, H, Liao, A Y, Rouse, P, Youshani, A S, Dridi, L, Martins, C, Levade, T, Stacey, K B, Davis, D M, Dyer, A, Clément, N, Björklund, T, Ali, R R, Agbandje-McKenna, M, Rahim, A A, Pshezhetsky, A, Waddington, S N, Linden, R M, Bigger, B W & Henckaerts, E 2018, ' A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency ', Brain, vol. 141, no. 7, pp. 2014-2031 . https://doi.org/10.1093/brain/awy126
Tordo, J, O'Leary, C, Antunes, A S L M, Palomar, N, Aldrin-Kirk, P, Basche, M, Bennett, A, D'Souza, Z, Gleitz, H, Godwin, A, Holley, R, Parker, H, Liao, A, Rouse, P, Youshani, A, Dridi, L, Martins, C, Levade, T, Stacey, K, Davis, D M, Dyer, A, Clement, N, Bjorklund, T, Ali, R R, Agbandje-McKenna, M, Rahim, A, Pshezhetsky, A V, Waddington, S N, Linden, R M, Bigger, B & Henckaerts, E 2018, ' A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency ', Brain, vol. 141, no. 7, pp. 2014-2031 . https://doi.org/10.1093/brain/awy126

مصطلحات موضوعية: 0301 basic medicine, Male, Neurotropism, Mucopolysaccharidosis, Genetic enhancement, viruses, medicine.disease_cause, Protein Engineering, Rats, Sprague-Dawley, Transduction (genetics), Mice, Mucopolysaccharidosis III, Transduction, Genetic, GENE-THERAPY VECTOR, Lysosomal storage disease, Tissue Distribution, Adeno-associated virus, VIRAL VECTORS, neurotropism, mucopolysaccharidosis, MOUSE MODEL, HEPARAN-SULFATE PROTEOGLYCAN, Dependovirus, 3. Good health, Cell biology, Capsid, CONGENITAL AMAUROSIS, Female, Life Sciences & Biomedicine, lysosomal transmembrane enzyme, RECEPTOR FOOTPRINT, Genetic Vectors, Clinical Neurology, adeno-associated virus, Biology, SANFILIPPO-SYNDROME, Virus, Retina, capsid engineering, 03 medical and health sciences, medicine, Animals, Photoreceptor Cells, HIPPOCAMPAL-LESIONS, Science & Technology, MUCOPOLYSACCHARIDOSIS-IIIB, Neurosciences, Original Articles, Genetic Therapy, NEURONAL CEROID-LIPOFUSCINOSIS, medicine.disease, Rats, Mice, Inbred C57BL, 030104 developmental biology, Neurosciences & Neurology, Neurology (clinical)

وصف الملف: application/pdf; Print

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b17a7608215d5ccd1f1e0191c5e9330

المؤلفون: Robin R. Ali, D. Frank P. Larkin, Mark Basche, Ulrich F O Luhmann, Alexander J. Smith, Anastasios Georgiadis, Daniel Kampik

المصدر: Investigative Opthalmology & Visual Science. 60:3170

مصطلحات موضوعية: genetic structures, Endothelium, Cell Count, Corneal Diseases, Corneal Transplantation, Small hairpin RNA, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, 030202 anesthesiology, medicine, Humans, RNA, Messenger, Cells, Cultured, Gene knockdown, Contact Inhibition, Chemistry, Endothelium, Corneal, Gene Transfer Techniques, Contact inhibition, Corneal Transplant, Cell biology, Transplantation, medicine.anatomical_structure, Gene Expression Regulation, Zonula Occludens-1 Protein, 030221 ophthalmology & optometry, Ex vivo, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f6b8d3ccba4df2331451fc30305295
https://doi.org/10.1167/iovs.18-26260

المؤلفون: Joshua T. Bartoe, Freya M. Mowat, Matthew J. Annear, Selina A. Azam, Robin R. Ali, Alexander J. Smith, Paul G. Curran, Simon M. Petersen-Jones, Janice Querubin, James W B Bainbridge, Mark Basche

المصدر: Human Gene Therapy. 24:883-893

مصطلحات موضوعية: cis-trans-Isomerases, medicine.medical_specialty, Pathology, genetic structures, Genetic enhancement, Genetic Vectors, Leber Congenital Amaurosis, Gene Expression, Retina, Dogs, Ophthalmology, Electroretinography, Genetics, medicine, Animals, Humans, Vision test, Vector (molecular biology), Fluorescein Angiography, Molecular Biology, Retinal pigment epithelium, medicine.diagnostic_test, business.industry, Vision Tests, Age Factors, Genetic Therapy, Dependovirus, Fluorescein angiography, eye diseases, body regions, Disease Models, Animal, Treatment Outcome, medicine.anatomical_structure, RPE65, Molecular Medicine, sense organs, business, Erg

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7530ada961dde910f20256eb1f2de3d6
https://doi.org/10.1089/hum.2013.146