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1دورية أكاديمية
المؤلفون: Ravi K Patel, Mark C Weir, Kexin Shen, Daniel Snyder, Vaughn S Cooper, Thomas E Smithgall
المصدر: PLoS ONE, Vol 14, Iss 12, p e0225887 (2019)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1932-6203
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2دورية أكاديمية
المؤلفون: Mark C Weir, Sabine Hellwig, Li Tan, Yao Liu, Nathanael S Gray, Thomas E Smithgall
المصدر: PLoS ONE, Vol 12, Iss 7, p e0181178 (2017)
وصف الملف: electronic resource
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المؤلفون: Daniel J. Snyder, Vaughn S. Cooper, Ravi K. Patel, Kexin Shen, Thomas E. Smithgall, Mark C. Weir
المصدر: PLoS ONE
PLoS ONE, Vol 14, Iss 12, p e0225887 (2019)مصطلحات موضوعية: 0301 basic medicine, Myeloid, Kinase Inhibitors, medicine.disease_cause, Biochemistry, Tyrosine Kinases, Hematologic Cancers and Related Disorders, 0302 clinical medicine, Mathematical and Statistical Techniques, Animal Cells, hemic and lymphatic diseases, Medicine and Health Sciences, Enzyme Inhibitors, Cell Analysis, Regulation of gene expression, Mutation, Multidisciplinary, Kinase, Gene Expression Regulation, Leukemic, Statistics, Gene Expression Regulation, Developmental, In Vitro Kinase Assay, hemic and immune systems, Hematology, Prognosis, Myeloid Leukemia, 3. Good health, Enzymes, Leukemia, Myeloid, Acute, medicine.anatomical_structure, src-Family Kinases, Bioassays and Physiological Analysis, Oncology, 030220 oncology & carcinogenesis, embryonic structures, Physical Sciences, Proto-Oncogene Proteins c-hck, Medicine, Regression Analysis, Cellular Types, Tyrosine kinase, psychological phenomena and processes, Proto-oncogene tyrosine-protein kinase Src, Research Article, Acute Myeloid Leukemia, Cell Viability Testing, Science, Mutation, Missense, Bone Marrow Cells, Biology, Research and Analysis Methods, 03 medical and health sciences, LYN, Cell Line, Tumor, Proto-Oncogene Proteins, Exome Sequencing, Leukemias, medicine, Genetics, Humans, Point Mutation, Pyrroles, Statistical Methods, Protein Kinase Inhibitors, Enzyme Assays, Biology and Life Sciences, Proteins, Cancers and Neoplasms, Cell Biology, body regions, 030104 developmental biology, Pyrimidines, Protein kinase domain, Amino Acid Substitution, fms-Like Tyrosine Kinase 3, Drug Resistance, Neoplasm, Cancer research, Enzymology, Biochemical Analysis, Protein Kinases, Mathematics
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المؤلفون: Ravi K. Patel, Li Chen, Sabine Hellwig, Li Tan, Nathanael S. Gray, Sherry T. Shu, Mark C. Weir, Thomas E. Smithgall
المصدر: ACS Chemical Biology. 13:1551-1559
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Myeloid, Proto-Oncogene Proteins c-hck, Administration, Oral, Syk, Antineoplastic Agents, Apoptosis, Biochemistry, Article, Mice, 03 medical and health sciences, LYN, Cell Line, Tumor, Proto-Oncogene Proteins, hemic and lymphatic diseases, medicine, Animals, Humans, Src family kinase, Protein Kinase Inhibitors, Aged, Aged, 80 and over, Chemistry, Kinase, General Medicine, Middle Aged, medicine.disease, Xenograft Model Antitumor Assays, Leukemia, Myeloid, Acute, Leukemia, src-Family Kinases, 030104 developmental biology, medicine.anatomical_structure, Benzamides, Quinazolines, Cancer research, Molecular Medicine, Female, Tyrosine kinase
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المؤلفون: Thomas E. Smithgall, Mark C. Weir, Nathanael S. Gray, Sabine Hellwig, Li Tan, Yao Liu
المصدر: PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0181178 (2017)مصطلحات موضوعية: 0301 basic medicine, Male, Myeloid, Pyridines, Kinase Inhibitors, lcsh:Medicine, Apoptosis, Biochemistry, Receptor tyrosine kinase, Piperazines, Tyrosine Kinases, Hematologic Cancers and Related Disorders, Animal Cells, hemic and lymphatic diseases, Medicine and Health Sciences, Enzyme Inhibitors, lcsh:Science, Aged, 80 and over, Multidisciplinary, biology, Cell Death, Myeloid leukemia, In Vitro Kinase Assay, hemic and immune systems, Hematology, Middle Aged, Myeloid Leukemia, 3. Good health, Enzymes, Precipitation Techniques, Leukemia, Myeloid, Acute, medicine.anatomical_structure, Bioassays and Physiological Analysis, Oncology, Tandem Repeat Sequences, Cell Processes, embryonic structures, Female, Cellular Types, Tyrosine kinase, Proto-Oncogene Proteins c-fes, psychological phenomena and processes, Signal Transduction, Research Article, Adult, Acute Myeloid Leukemia, Bone Marrow Cells, Research and Analysis Methods, Cell Growth, 03 medical and health sciences, Inhibitory Concentration 50, Cell Line, Tumor, Leukemias, medicine, Humans, Immunoprecipitation, Pyrroles, Kinase activity, Protein Kinase Inhibitors, Aged, Enzyme Assays, Cell growth, lcsh:R, Biology and Life Sciences, Cancers and Neoplasms, Proteins, Cell Biology, Molecular biology, body regions, 030104 developmental biology, Pyrimidines, fms-Like Tyrosine Kinase 3, Fms-Like Tyrosine Kinase 3, Mutation, biology.protein, Quinazolines, Enzymology, Pyrazoles, lcsh:Q, Biochemical Analysis, Protein Kinases
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6Abstract 2363: Targeting Src-family kinases to combat acquired inhibitor resistance in FLT3-ITD+ AML
المصدر: Cancer Research. 77:2363-2363
مصطلحات موضوعية: Cancer Research, Oncology, Kinase, Cancer research, Inhibitor resistance, Biology, Src family, Flt3 itd
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8e9029788270d85d3ecbb0dad90ae70c
https://doi.org/10.1158/1538-7445.am2017-2363 -
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المؤلفون: Jill B. Keeney, Mark C. Weir
المصدر: Methods in Molecular Biology ISBN: 9781493913626
مصطلحات موضوعية: Genetics, Cloning, Mutation, Transformation (genetics), Plasmid, medicine, Mutagenesis (molecular biology technique), Biology, Homologous recombination, medicine.disease_cause, Gene, Yeast
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1973ce8e83565d008ac322feef2416c5
https://doi.org/10.1007/978-1-4939-1363-3_3 -
8Abstract B180: Multi-targeted tyrosine kinase inhibitors potently suppress FLT3-ITD+ AML cell growth
المؤلفون: Thomas E. Smithgall, Sabine Hellwig, Mark C. Weir, Nathanael S. Gray, Ravi Patel
المصدر: Molecular Cancer Therapeutics. 14:B180-B180
مصطلحات موضوعية: Cancer Research, Tyrosine-protein kinase CSK, medicine.drug_class, Kinase, Biology, Tyrosine-kinase inhibitor, Receptor tyrosine kinase, Oncology, Biochemistry, LYN, hemic and lymphatic diseases, Mitogen-activated protein kinase, medicine, biology.protein, Cancer research, Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e064faf0bb85629cdd87a871a189213c
https://doi.org/10.1158/1535-7163.targ-15-b180 -
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المؤلفون: Jill B. Keeney, Mark C. Weir
المصدر: The FASEB Journal. 25
مصطلحات موضوعية: Transposition (music), Genetics, Regulator, Biology, Molecular Biology, Biochemistry, Yeast, Biotechnology, Cell biology
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المؤلفون: Nathanael S. Gray, Thomas E. Smithgall, Sabine Hellwig, Mark C. Weir
المصدر: Clinical Cancer Research. 21:A25-A25
مصطلحات موضوعية: Cancer Research, biology, Cell growth, Kinase, Lestaurtinib, Receptor tyrosine kinase, Oncology, Biochemistry, hemic and lymphatic diseases, biology.protein, Cancer research, medicine, Phosphorylation, Kinase activity, Signal transduction, Tyrosine kinase, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7e5f5afd663e3ba4671b3a316166ac93
https://doi.org/10.1158/1557-3265.hemmal14-a25