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1دورية أكاديمية
المؤلفون: Nadine Alvarez, Gregory C. Adam, John A. Howe, Vijeta Sharma, Matthew D. Zimmerman, Enriko Dolgov, Risha Rasheed, Fatima Nizar, Khushboo Sahay, Andrew M. Nelson, Steven Park, Xiaoyan Zhou, Christine Burlein, John F. Fay, Daniel V. Iwamoto, Carolyn M. Bahnck-Teets, Krista L. Getty, Shih Lin Goh, Imad Salhab, Keith Smith, Christopher W. Boyce, Tamara D. Cabalu, Nicholas Murgolo, Nicholas G. Fox, Todd W. Mayhood, Valerie W. Shurtleff, Mark E. Layton, Craig A. Parish, John A. McCauley, David B. Olsen, David S. Perlin
المصدر: Viruses, Vol 16, Iss 7, p 1158 (2024)
مصطلحات موضوعية: coronavirus, SARS-CoV-2, MERS-CoV, 3CLPro, antivirals, protease inhibitors, Microbiology, QR1-502
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Rebecca M. Klein, Mark E. Layton, Hillary Regan, Christopher P. Regan, Yuxing Li, Tracey Filzen, Matt Cato, Michelle K. Clements, Jixin Wang, Raul Sanoja, Thomas J. Greshock, Anthony J. Roecker, Joseph E. Pero, Ron Kim, Christopher Burgey, Christopher T. John, Ying-Hong Wang, Neetesh Bhandari, Arie Struyk, Richard L. Kraus, Darrell A. Henze, Andrea K. Houghton
المصدر: Channels, Vol 16, Iss 1, Pp 230-243 (2022)
مصطلحات موضوعية: Sodium channel inhibitor, respiration, selectivity, phrenic nerve, Therapeutics. Pharmacology, RM1-950, Physiology, QP1-981
وصف الملف: electronic resource
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المؤلفون: Mark E. Layton, Jeffrey C. Kern, Timothy J. Hartingh, William D. Shipe, Izzat Raheem, Monika Kandebo, Robert P. Hayes, Sarah Huszar, Donnie Eddins, Bennett Ma, Joy Fuerst, Gordon K. Wollenberg, Jing Li, Jeff Fritzen, Georgia B. McGaughey, Jason M. Uslaner, Sean M. Smith, Paul J. Coleman, Christopher D. Cox
المصدر: Journal of Medicinal Chemistry. 66:1157-1171
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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المؤلفون: Christopher Daley, Yuxing Li, Haiyan Sun, Xiu Wang, Fuqiang Zhao, Michelle K. Clements, Rebecca M. Klein, Aneta Jovanovska, Andrew Brunskill, Joseph E. Pero, Xuanjia Peng, Thomas J. Greshock, Christopher S. Burgey, Mark E. Layton, Jeanine E. Ballard, Deping Wang, Richard L. Kraus, Andrea K. Houghton, Anthony J. Roecker, Michael J. Kelly
المصدر: ACS Medicinal Chemistry Letters. 12:1038-1049
مصطلحات موضوعية: 010405 organic chemistry, business.industry, Organic Chemistry, Pharmacology, 01 natural sciences, Biochemistry, 0104 chemical sciences, Olfactory response, 010404 medicinal & biomolecular chemistry, IVIVC, Drug Discovery, NAV1, Potency, Medicine, business, Selectivity
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المؤلفون: Richard L. Kraus, Ronald M. Kim, Jeanine E. Ballard, Thomas J. Greshock, Andrea K. Houghton, Michelle K. Clements, Marie A. Holahan, Andrew Danziger, Christopher S. Burgey, Yuxing Li, Mark E. Layton, Jordi Serra, Parul S. Pall, Rebecca M. Klein, Joshua D. Vardigan, Dan Zhou, Fuqiang Zhao, Christopher Daley, Darrell A. Henze
المصدر: Science Translational Medicine. 13
مصطلحات موضوعية: biology, business.industry, General Medicine, Olfaction, Microneurography, Pharmacology, biology.organism_classification, Olfactory bulb, Rhesus macaque, Electrophysiology, Nociception, In vivo, Nociceptor, Medicine, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2568b727c558da3b3a2a03b719a658df
https://doi.org/10.1126/scitranslmed.aay1050 -
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المؤلفون: Anthony J, Roecker, Mark E, Layton, Joseph E, Pero, Michael J, Kelly, Thomas J, Greshock, Richard L, Kraus, Yuxing, Li, Rebecca, Klein, Michelle, Clements, Christopher, Daley, Aneta, Jovanovska, Jeanine E, Ballard, Deping, Wang, Fuqiang, Zhao, Andrew P J, Brunskill, Xuanjia, Peng, Xiu, Wang, Haiyan, Sun, Andrea K, Houghton, Christopher S, Burgey
المصدر: ACS Med Chem Lett
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7
المؤلفون: Andrea K. Houghton, Aneta Jovanovska, Tracey Filzen, Ying-Hong Wang, Jacqueline Panigel, Annie Liang, Michelle K. Clements, Rebecca M. Klein, Richard L. Kraus, John Majercak, Eleftheria N. Finger, Jixin Wang, Matthew J. Cato, Hannah D. G. F. Lehman, Christopher Daley, Yun Gregan, James Mulhearn, Yuxing Li, Michael A. Rossi, Darrell A. Henze, Mark O. Urban, Michael J. Kelly, Scott E. Wolkenberg, Mark E. Layton, Joseph E. Pero
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:2683-2688
مصطلحات موضوعية: 0301 basic medicine, Ligand efficiency, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Bioavailability, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, In vivo, Oral administration, Drug Discovery, Molecular Medicine, Structure–activity relationship, Potency, Selectivity, Molecular Biology, Lead compound
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المؤلفون: Mark E. Layton, Eleftheria N. Finger, Edward C. Sherer, Amy Jo Koser, Aneta Jovanovska, Robert Gomez, Xiu Wang, Deping Wang, Xuanjia Peng, John Majercak, Melissa Egbertson, Paul J. Coleman, Rebecca M. Klein, Kristen L.G. Jones, Richard L. Kraus, Jixin Wang, Tracey Filzen, Mark O. Urban, Yuxing Li, Anthony J. Roecker, Matthew J. Cato, Ying-Hong Wang, Michelle K. Clements, Jacqueline Panigel, Leo A. Joyce, Vincent P. Santarelli, Irene Gregan, Christopher Daley, Haiyan Sun, Andrea K. Houghton
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:2087-2093
مصطلحات موضوعية: 0301 basic medicine, Gene isoform, Side effect, Chemistry, Sodium channel, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Bioavailability, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Drug Discovery, NAV1, Molecular Medicine, Potency, Molecular Biology, 030217 neurology & neurosurgery
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المؤلفون: Richard L, Kraus, Fuqiang, Zhao, Parul S, Pall, Dan, Zhou, Joshua D, Vardigan, Andrew, Danziger, Yuxing, Li, Christopher, Daley, Jeanine E, Ballard, Michelle K, Clements, Rebecca M, Klein, Marie A, Holahan, Thomas J, Greshock, Ronald M, Kim, Mark E, Layton, Christopher S, Burgey, Jordi, Serra, Darrell A, Henze, Andrea K, Houghton
المصدر: Science translational medicine. 13(594)
مصطلحات موضوعية: Nociception, NAV1.7 Voltage-Gated Sodium Channel, Animals, Humans, Nociceptors, Pain, Macaca mulatta
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f9833016998efa2956e0258637677db9
https://pubmed.ncbi.nlm.nih.gov/34011626 -
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المؤلفون: Michael J. Kelly, Marlene A. Jacobson, Kerry L. Fillgrove, Alexander J. Reif, Ken Arrington, Robert M. Garbaccio, Kevin J. Rodzinak, Cheng Wang, Timothy J. Hartingh, Brian C. Magliaro, Sarah L. Huszar, Yuhsin Kuo, Cuyue Tang, Jason M. Uslaner, Vadim Y. Dudkin, Julie A. O'Brien, Mark E. Layton
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:1260-1264
مصطلحات موضوعية: 0301 basic medicine, Pyridines, Pyridones, Clinical Biochemistry, Allosteric regulation, Drug Evaluation, Preclinical, Pharmaceutical Science, Pharmacology, Receptors, Metabotropic Glutamate, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, Drug Discovery, Animals, Potency, Structure–activity relationship, Receptor, Molecular Biology, Chemistry, Organic Chemistry, Imidazoles, Glutamate receptor, Rats, Disease Models, Animal, 030104 developmental biology, Metabotropic receptor, Psychotic Disorders, Metabotropic glutamate receptor, Molecular Medicine, Metabotropic glutamate receptor 2, Locomotion, 030217 neurology & neurosurgery, Protein Binding