المؤلفون: Marta Poblocka, Akang Leonard Bassey, Victoria M. Smith, Marta Falcicchio, Ana Sousa Manso, Mohammad Althubiti, XiaoBo Sheng, Andrew Kyle, Ruth Barber, Mark Frigerio, Salvador Macip

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/0025965e081a437187edf55f3e63aa33

المؤلفون: Nick Evans, Ruslan Grygorash, Paul Williams, Andrew Kyle, Terrence Kantner, Ravindra Pathak, XiaoBo Sheng, Fabio Simoes, Hiteshri Makwana, Ricardo Resende, Elena de Juan, Alan Jenkins, David Morris, Aurelie Michelet, Frances Jewitt, Felicity Rudge, Nicolas Camper, Anaïs Manin, William McDowell, Martin Pabst, Antony Godwin, Mark Frigerio, Matthew Bird

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: antibody drug conjugate (ADC), crown ether, cyclodextrin, in vivo, xenograft, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.764540/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/e322c470d7fb4d25b6de4ac481fa6602

المؤلفون: Katherine Griffiths, Uli Binder, William McDowell, Rita Tommasi, Mark Frigerio, William G. Darby, Chris G. Hosking, Lionel Renaud, Matthias Machacek, Peter Lloyd, Arne Skerra, Michael Foley

المصدر: mAbs, Vol 11, Iss 7, Pp 1331-1340 (2019)

مصطلحات موضوعية: Half-life extension, i-body, PA600, PEGylation, CXCR4, pharmacokinetics, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/7654a6ff13a34f68ab979ca90ac88158

المؤلفون: Kristoffer Valerie, Timothy van Meter, Lawrence F. Povirk, Mark J. O'Connor, Keith A. Menear, Laurent Rigoreau, Marc Hummersone, Wei Yee Chong, Xiaoling F. Cockcroft, Mark Frigerio, Isa Hussaini, Nicholas Valerie, Elizabeth Rosenberg, Sarah E. Golding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9427b6f42606cf9cfd80b7c24538468c
https://doi.org/10.1158/1535-7163.22485738.v1

المؤلفون: Kristoffer Valerie, Timothy van Meter, Lawrence F. Povirk, Mark J. O'Connor, Keith A. Menear, Laurent Rigoreau, Marc Hummersone, Wei Yee Chong, Xiaoling F. Cockcroft, Mark Frigerio, Isa Hussaini, Nicholas Valerie, Elizabeth Rosenberg, Sarah E. Golding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63df1a3370c90e12a492a8e058827180
https://doi.org/10.1158/1535-7163.c.6532065

المؤلفون: Akang Leonard Bassey, Ana Sousa Manso, Mohammad Althubiti, Mark Frigerio, Andrew F. Kyle, Victoria M. Smith, Marta Poblocka, Marta Falcicchio, Ruth C. Barber, XiaoBo Sheng, Salvador Macip

المساهمون: Universitat Oberta de Catalunya (UOC), University of Leicester, Babraham Research Campus

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
O2, repositorio institucional de la UOC
Universitat Oberta de Catalunya (UOC)
Scientific Reports

مصطلحات موضوعية: Senescence, Antibody-drug conjugate, Immunoconjugates, Science, Biology, Medical sciences, Epitope, Article, Cell Line, Duocarmycins, In vivo, Fibrosis, Senotherapeutics, target identification, Target identification, medicine, marcador biológico, Humans, identificació d'objectius, marcador biològic, Senolytic, Cellular Senescence, Ciències de la salut, identificación de objetivos, Multidisciplinary, medicine.disease, biological marker, Isotype, senescence cells, Ciencias de la salud, Gene Expression Regulation, cèl·lules senescents, biology.protein, Cancer research, Medicine, Antibody, Tumor Suppressor Protein p53, células senescentes, beta 2-Microglobulin

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72cffcb2cd40568d3010318bf31c8338
https://doaj.org/article/0025965e081a437187edf55f3e63aa33

المؤلفون: Nick, Evans, Ruslan, Grygorash, Paul, Williams, Andrew, Kyle, Terrence, Kantner, Ravindra, Pathak, XiaoBo, Sheng, Fabio, Simoes, Hiteshri, Makwana, Ricardo, Resende, Elena, de Juan, Alan, Jenkins, David, Morris, Aurelie, Michelet, Frances, Jewitt, Felicity, Rudge, Nicolas, Camper, Anaïs, Manin, William, McDowell, Martin, Pabst, Antony, Godwin, Mark, Frigerio, Matthew, Bird

المصدر: Frontiers in pharmacology. 13

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::c0c163869b09e4c7d83d87923217ec72
https://pubmed.ncbi.nlm.nih.gov/35784686

المؤلفون: Michael Foley, Rita Tommasi, Katherine Merne Griffiths, Mark Frigerio, Matthias Machacek, Lionel Renaud, Arne Skerra, Uli Binder, William G. Darby, William McDowell, Christopher G. Hosking, Peter Lloyd

المصدر: mAbs

مصطلحات موضوعية: Male, Receptors, CXCR4, Proline, Half-life extension, Immunology, Peptide, Bioengineering, Pharmacology, CXCR4, PA600, Polyethylene Glycols, Rats, Sprague-Dawley, 03 medical and health sciences, Mice, 0302 clinical medicine, Pharmacokinetics, Report, PEG ratio, Immunology and Allergy, Medicine, Animals, Humans, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Mice, Inbred ICR, Alanine, biology, i-body, business.industry, PEGylation, Half-life, Single-Domain Antibodies, Rats, Macaca fascicularis, chemistry, 030220 oncology & carcinogenesis, biology.protein, Antibody, business, Conjugate, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f974fbe950bbe3e9022c25191b4ea958
http://europepmc.org/articles/PMC6748587

المؤلفون: João M. Nunes, Mark Frigerio, Matthew Bird

المصدر: Methods in Molecular Biology ISBN: 9781493999286

مصطلحات موضوعية: chemistry.chemical_classification, Aqueous solution, Chemistry, Payload (computing), 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, Amino acid, law.invention, Homogeneous, law, Michael reaction, Recombinant DNA, 0210 nano-technology, Conjugate, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b31de86eb0052394bdf99c9bcaea5f98
https://doi.org/10.1007/978-1-4939-9929-3_8

المؤلفون: Matthew, Bird, Joao, Nunes, Mark, Frigerio

المصدر: Methods in molecular biology (Clifton, N.J.). 2078

مصطلحات موضوعية: Chromatography, Structure-Activity Relationship, Immunoconjugates, Drug Development, Antibodies, Monoclonal, Humans, Cysteine, Disulfides, Antibodies, Monoclonal, Humanized, Hydrophobic and Hydrophilic Interactions

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9b861e0856133d70a030a13d94c0f57c
https://pubmed.ncbi.nlm.nih.gov/31643053