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المؤلفون: Holger Sellner, Emilie Chapeau, Pascal Furet, Markus Voegtle, Bahaa Salem, Mickaël Le Douget, Vincent Bordas, Jean‐Marc Groell, Anne‐Laure Le Goff, Christine Rouzet, Thomas Wietlisbach, Thomas Zimmermann, Joseph McKenna, Cara E. Brocklehurst, Patrick Chène, Markus Wartmann, Clemens Scheufler, Joerg Kallen, Gareth Williams, Stephanie Harlfinger, Martin Traebert, Bérengère M. Dumotier, Tobias Schmelzle, Nicolas Soldermann
المصدر: ChemMedChem.
مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry
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المؤلفون: Pascal Furet, Vincent Bordas, Mickaël Le Douget, Bahaa Salem, Yannick Mesrouze, Patricia Imbach‐Weese, Holger Sellner, Markus Voegtle, Nicolas Soldermann, Emilie Chapeau, Markus Wartmann, Clemens Scheufler, Cesar Fernandez, Joerg Kallen, Vito Guagnano, Patrick Chène, Tobias Schmelzle
المصدر: ChemMedChem. 17
مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry
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3
المؤلفون: Pascal Furet, Vincent Bordas, Mickaël Le Douget, Bahaa Salem, Yannick Mesrouze, Patricia Imbach‐Weese, Holger Sellner, Markus Voegtle, Nicolas Soldermann, Emilie Chapeau, Markus Wartmann, Clemens Scheufler, Cesar Fernandez, Joerg Kallen, Vito Guagnano, Patrick Chène, Tobias Schmelzle
المصدر: ChemMedChem. 17(19)
مصطلحات موضوعية: Pharmacology, Neoplasms, Organic Chemistry, Drug Discovery, Molecular Medicine, Humans, YAP-Signaling Proteins, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry, Adaptor Proteins, Signal Transducing, Transcription Factors
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4
المؤلفون: Tobias Schmelzle, Emilie Chapeau, Daniel Bauer, Patrick Chene, Jason Faris, Cesar Fernandez, Pascal Furet, Giorgio Galli, Jiachang Gong, Stephanie Harlfinger, Francesco Hofmann, Eloisa Jimenez Nunez, Joerg Kallen, Thanos Mourikis, Laurent Sansregret, Paulo Santos, Clemens Scheufler, Holger Sellner, Markus Voegtle, Markus Wartmann, Peter Wessels, Frederic Zecri, Nicolas Soldermann
المصدر: Cancer Research. 83:LB319-LB319
مصطلحات موضوعية: Cancer Research, Oncology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ad77e2db1f0369ac9729c839360bd713
https://doi.org/10.1158/1538-7445.am2023-lb319 -
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المؤلفون: Jean-Michel Rondeau, Heinrich Rueeger, Rainer Martin Lueoend, Laura H. Jacobson, Markus Voegtle, Rainer Machauer, Grit Laue, Philipp Holzer, Konstanze Hurth, Siem Jacob Veenstra, Matthias Staufenbiel, Marina Tintelnot-Blomley, Ulf Neumann, Mathias Frederiksen
المصدر: Journal of Medicinal Chemistry. 64:4677-4696
مصطلحات موضوعية: Central nervous system, Thiazines, Molecular Dynamics Simulation, Pharmacology, Crystallography, X-Ray, 01 natural sciences, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Alzheimer Disease, Oxazines, Drug Discovery, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Potency, Enzyme Inhibitors, Picolinic Acids, 030304 developmental biology, 0303 health sciences, Amyloid beta-Peptides, Binding Sites, Trifluoromethyl, Treatment regimen, Brain, Penetration (firestop), Rats, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, medicine.anatomical_structure, chemistry, β secretase, Molecular Medicine, Efflux, Amyloid Precursor Protein Secretases, Lead compound, Half-Life
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6
المؤلفون: Strang Ross Sinclair, Markus Streiff, Daniel J. McKay, Johannes Ottl, Andreas Billich, Claudia Betschart, Stephanie Harlfinger, Eloísa Jiménez-Núñez, Nigel Graham Cooke, Christine Guntermann, Markus Voegtle, Janet Dawson, Samuel Hintermann, Klemens Kaupmann, Rowan Stringer, Christian Beerli, Nathalie Gobeau, Juergen Wagner, Klemens Hoegenauer, Joerg Kallen, Peter Ertl
المصدر: Journal of Medicinal Chemistry. 62:10816-10832
مصطلحات موضوعية: chemistry.chemical_classification, Orphan receptor, 0303 health sciences, Chemistry, Carboxylic acid, Retinoic acid, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, Proinflammatory cytokine, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, In vivo, Lipophilic efficiency, RAR-related orphan receptor gamma, Drug Discovery, Molecular Medicine, 030304 developmental biology, ADME
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المؤلفون: Ulf Neumann, Rainer Machauer, Markus Voegtle, Marina Tintelnot-Blomley, Konstanze Hurth, Grit Laue, Siem Jacob Veenstra, Rainer Martin Lueoend, Karen Beltz, Jean-Michel Rondeau, Laura H. Jacobson, Heinrich Rueeger
المصدر: Journal of medicinal chemistry. 64(20)
مصطلحات موضوعية: Male, Central nervous system, Disease, Pharmacology, Cell Line, Rats, Sprague-Dawley, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Dogs, Pharmacokinetics, Alzheimer Disease, Drug Discovery, Oxazines, medicine, Potency, Animals, Aspartic Acid Endopeptidases, Humans, Enzyme Inhibitors, Trifluoromethyl, Dose-Response Relationship, Drug, Molecular Structure, Rats, Mice, Inbred C57BL, medicine.anatomical_structure, chemistry, β secretase, Molecular Medicine, Efflux, Amyloid Precursor Protein Secretases, Lead compound
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8
المؤلفون: Klemens, Hoegenauer, Joerg, Kallen, Eloísa, Jiménez-Núñez, Ross, Strang, Peter, Ertl, Nigel G, Cooke, Samuel, Hintermann, Markus, Voegtle, Claudia, Betschart, Daniel J J, McKay, Juergen, Wagner, Johannes, Ottl, Christian, Beerli, Andreas, Billich, Janet, Dawson, Klemens, Kaupmann, Markus, Streiff, Nathalie, Gobeau, Stephanie, Harlfinger, Rowan, Stringer, Christine, Guntermann
المصدر: Journal of medicinal chemistry. 62(23)
مصطلحات موضوعية: Male, Models, Molecular, Dose-Response Relationship, Drug, Molecular Structure, Imidazoles, Administration, Oral, Nuclear Receptor Subfamily 1, Group F, Member 3, Rats, Drug Design, Fluorescence Resonance Energy Transfer, Animals, Female, Hypersensitivity, Delayed, Half-Life
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9
المؤلفون: Markus Voegtle, Laura H. Jacobson, Heinrich Rueeger, Mathias Frederiksen, Ulf Neumann, Rainer Martin Lueoend, Rainer Machauer, Marina Tintelnot-Blomley, Jean-Michel Rondeau, Philipp Holzer, Siem Jacob Veenstra, Konstanze Hurth, Matthias Staufenbiel
المصدر: Bioorganic & Medicinal Chemistry Letters. 28:2195-2200
مصطلحات موضوعية: Models, Molecular, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Oxazines, 01 natural sciences, Biochemistry, Madin Darby Canine Kidney Cells, Mice, Structure-Activity Relationship, Dogs, Drug Discovery, Hydrolase, Animals, Aspartic Acid Endopeptidases, Potency, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Dose-Response Relationship, Drug, 010405 organic chemistry, Chemistry, Treatment regimen, Organic Chemistry, Cell model, Permeation, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Molecular Medicine, Amyloid Precursor Protein Secretases
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المؤلفون: Andreas Marzinzik, Markus Voegtle
المصدر: QSAR & Combinatorial Science. 23:440-459
مصطلحات موضوعية: chemistry.chemical_compound, Solid-phase synthesis, Chemistry, Drug discovery, Phase (matter), Organic Chemistry, Drug Discovery, Quinazoline, Organic chemistry, General Medicine, Combinatorial chemistry, Computer Science Applications