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1
المؤلفون: Donald P. McDonnell, John D. Norris, Dmitri Kazmin, Scott K. Thompson, Jaclyn R. Patterson, Marlys Hammond, Walter Trizna, Nicholas J. Laping, Jeffrey D. Bray, Christine G. Schnackenberg, Daniel E. Frigo, Andrea B. Sherk
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e83eb3282c67e787f8942ba5a7c35a
https://doi.org/10.1158/0008-5472.c.6498402 -
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المؤلفون: Donald P. McDonnell, John D. Norris, Dmitri Kazmin, Scott K. Thompson, Jaclyn R. Patterson, Marlys Hammond, Walter Trizna, Nicholas J. Laping, Jeffrey D. Bray, Christine G. Schnackenberg, Daniel E. Frigo, Andrea B. Sherk
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd34ad071b42869122db0e920ae8004b
https://doi.org/10.1158/0008-5472.22377012.v1 -
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المؤلفون: Eidam Hilary Schenck, Theresa J. Roethke, Linda S. Barton, Fox Ryan Michael, Steve Zhao, Kevin S. Thorneloe, David J. Behm, Guosen Ye, Patrick Stoy, Mui Cheung, Tram H. Hoang, Dennis A. Holt, Krista B. Goodman, Brian G. Lawhorn, Marlys Hammond, Mark A. Hilfiker, Carl Brooks, Jaclyn R. Patterson
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: TRPV4, 010405 organic chemistry, Chemistry, Organic Chemistry, Pharmacology, medicine.disease, Pulmonary edema, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Transient receptor potential channel, Pharmacokinetics, In vivo, Heart failure, Drug Discovery, medicine, Potency, Ion channel
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المؤلفون: Theresa J. Roethke, Guosen Ye, Hong Zhang, Robert T. Gampe, Robert A. Reid, Brian G. Lawhorn, Tram H. Hoang, Dennis A. Holt, Bob Willette, Marlys Hammond, David G. Washburn, Sharada Manns, Mark A. Hilfiker, Steve Zhao, Fox Ryan Michael, Joanne Prendergast, Eidam Hilary Schenck, Amy M. Quinn, Lara S. Kallander, Sarah E. Dowdell, Alan R. Rendina, Elsie Diaz, Xuan Hong
المصدر: ACS Medicinal Chemistry Letters. 9:736-740
مصطلحات موضوعية: 0301 basic medicine, Metalloproteinase, CYP3A4, Chemistry, Organic Chemistry, TLL1, Biochemistry, Small molecule, Bone morphogenetic protein 1, 03 medical and health sciences, 030104 developmental biology, In vivo, Drug Discovery, Hydrolase, Selectivity
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المؤلفون: Dennis A. Holt, Gatto Gregory J, Joanne Philp, Sharon Sweitzer, Marlys Hammond, Guofeng Zhang, Mui Cheung, Rachel D. Totoritis, Lisa M. Shewchuk, Liping Wang, Huizhen Zhao, Benjamin Schwartz, Joshua E. Cottom, Harvey E. Fries, Brian G. Lawhorn, Hu Li, Alan P. Graves, Hongwei Qi, Yongdong Zhao, Lara S. Kallander, Christopher Louer
المصدر: Journal of Medicinal Chemistry. 58:7431-7448
مصطلحات موضوعية: Male, Purine, Protein Conformation, Administration, Oral, Protein Serine-Threonine Kinases, Crystallography, X-Ray, Cell Line, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, Troponin I, Animals, Humans, Structure–activity relationship, Purine metabolism, Sulfonamides, MAP kinase kinase kinase, Kinase, MAP Kinase Kinase Kinases, In vitro, chemistry, Biochemistry, Purines, Molecular Medicine, Protein Binding
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المؤلفون: Marlys Hammond, David A. Griffith, Philip A. Carpino, Steven R. Schneider, Robert L. Dow, Paul DaSilva-Jardine, John R. Hadcock, Philip A. Iredale, Dennis O. Scott, Ernest S. Paight
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:5351-5354
مصطلحات موضوعية: Models, Molecular, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Hydrazide, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Piperidines, Receptor, Cannabinoid, CB1, Rimonabant, Drug Discovery, medicine, Animals, Humans, Moiety, Molecular Biology, Organic Chemistry, Imidazoles, Biological activity, Rats, chemistry, Pyrazoles, Molecular Medicine, Bioisostere, Cannabinoid, Pharmacophore, Isopropyl, medicine.drug
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المؤلفون: Rakesh Nagilla, Sharada Manns, Eugene L. Stewart, Marlys Hammond, Tram H. Hoang, Scott K. Thompson, Walter Trizna, Chaya Duraiswami, Eugene T. Grygielko, Thuy B. Tran, James S. Frazee, Kevin P. Madauss, Johnson Latisha C, Shawn P. Williams, Lindsay E. Glace, David G. Washburn, Jeffrey D. Bray
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:4664-4668
مصطلحات موضوعية: Agonist, medicine.drug_class, Stereochemistry, Clinical Biochemistry, hERG, Administration, Oral, Pharmaceutical Science, Pharmacology, Biochemistry, Partial agonist, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, Progesterone receptor, medicine, Animals, Humans, Pyrrolidinones, Molecular Biology, Binding Sites, biology, Organic Chemistry, Haplorhini, Ether-A-Go-Go Potassium Channels, Rats, Nuclear receptor, chemistry, biology.protein, Molecular Medicine, Receptors, Progesterone, Lead compound
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المؤلفون: Terrell A. Patterson, James V. Cassella, Paul DaSilva-Jardine, R W Stevenson, Li She, Diane M. Hargrove, Kelly A. Martin, Richard L. Elliott, Robert M. Oliver, Marlys Hammond, Christine M. Mack, J. Cory Kalvass, Tristan S. Maurer, Morgan Bradley P
المصدر: Journal of Medicinal Chemistry. 46:670-673
مصطلحات موضوعية: Male, Hydrochloride, Stereochemistry, In Vitro Techniques, Pancreatic Polypeptide, Chemical synthesis, Rats, Sprague-Dawley, Eating, chemistry.chemical_compound, In vivo, Nitriles, Drug Discovery, Tumor Cells, Cultured, Animals, Humans, Tissue Distribution, Rats, Wistar, Receptor, Cerebrospinal Fluid, Chemistry, Imidazoles, Antagonist, Brain, In vitro, Rats, Receptors, Neuropeptide Y, Benzonitrile, Anorectic, Molecular Medicine, Calcium, Cattle
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المؤلفون: Ralf Glatthar, Philip M. Harrington, Scott E. Schaus, Elaine Y. Kuo, Jia-Ning Xiang, Jun Liang, Andrew G. Myers, Yusheng Wu, Marlys Hammond
المصدر: Journal of the American Chemical Society. 124:5380-5401
مصطلحات موضوعية: Models, Molecular, Allylic rearrangement, Glycosylation, Intramolecular reaction, Tritium, Biochemistry, Catalysis, Silyl ether, chemistry.chemical_compound, Colloid and Surface Chemistry, Zinostatin, medicine, Organic chemistry, Carbon Radioisotopes, Antibiotics, Antineoplastic, Neocarzinostatin, Enantioselective synthesis, Total synthesis, Stereoisomerism, General Chemistry, Chromophore, chemistry, Isotope Labeling, Yield (chemistry), Enediynes, medicine.drug
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المؤلفون: Andrew G. Myers, Marlys Hammond, Michael E. Kort
المصدر: Journal of the American Chemical Society. 119:2965-2972
مصطلحات موضوعية: chemistry.chemical_classification, Neocarzinostatin, General Chemistry, Chromophore, Carbohydrate, Biochemistry, Catalysis, Residue (chemistry), chemistry.chemical_compound, Colloid and Surface Chemistry, chemistry, Enediyne, medicine, Thiol, Reactivity (chemistry), DNA, medicine.drug