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المؤلفون: Kaori Hiraga, Peter Corbett Liu, Yan Li, Yang Shen, Marshall Snavely
المصدر: Journal of Biomolecular Screening
مصطلحات موضوعية: Immunoconjugates, media_common.quotation_subject, education, cell-based assay, Fluorescent Antibody Technique, Antineoplastic Agents, Endocytosis, Biochemistry, antibody screening, Analytical Chemistry, Antigen, Downregulation and upregulation, Cell Line, Tumor, quencher dye, Humans, Cytotoxic T cell, Internalization, Direct fluorescent antibody, Fluorescent Dyes, Original Research, degradation, media_common, biology, flow cytometry, Antibodies, Monoclonal, Primary and secondary antibodies, Molecular biology, High-Throughput Screening Assays, Cell biology, internalization, Protein Transport, Proteolysis, biology.protein, Molecular Medicine, fluorescent dye, Drug Screening Assays, Antitumor, Antibody, antibody labeling, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31141da1eddb2dc2b4c19df01d04b1d4
https://doi.org/10.1177/1087057115588511 -
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المؤلفون: David Surguladze, Kris Persaud, Douglas Burtrum, Sudhakar Chintharlapalli, Aiping Zhu, Marie Prewett, Sagit Hindi, Paul Balderes, Ruslan Novosyadlyy, Yun (Kenneth) Kang, Haifan Zhang, Scott W. Eastman, Juqun Shen, Yang Shen, Lin Zeng, Zhenping Zhu, Nicole Covino, Michael Topper, Marshall Snavely, Dale L. Ludwig, Andrew Ihor Korytko, Amelie Forest, Victor J. Wroblewski
المصدر: mAbs
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Angiogenesis, medicine.medical_treatment, Antibody Affinity, Receptor, IGF Type 1, angiogenesis, antibody fusion, Mice, Antibodies, Bispecific, Immunology and Allergy, Chromatography, High Pressure Liquid, degradation, Microscopy, Confocal, Protein Stability, Antibodies, Monoclonal, Ligand (biochemistry), VEGF, Cell biology, bispecific antibody, VEGFR2, VEGFR1, Female, Signal transduction, Antibody, medicine.drug_class, IGF-IR, Recombinant Fusion Proteins, Immunology, Immunoblotting, Mice, Nude, bi-functional antibody, Enzyme-Linked Immunosorbent Assay, Biology, Monoclonal antibody, Antibody receptor, Report, medicine, Animals, Humans, Immunoprecipitation, Growth factor, Receptors, Somatomedin, Neoplasms, Experimental, Surface Plasmon Resonance, Fusion protein, Molecular biology, Antibodies, Neutralizing, Xenograft Model Antitumor Assays, internalization, biology.protein
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المؤلفون: Jacqueline Lypowy, Marshall Snavely, Kris Persaud, Amtul Bari, Wei Zhu, Zhiping Weng, Brian G. Pierce, Jaafar N. Haidar, Dale L. Ludwig, Xenia Luna
المصدر: Journal of Molecular Biology. 426:1583-1599
مصطلحات موضوعية: chemistry.chemical_classification, Protein Conformation, Stereochemistry, Hydrogen bond, Chemistry, Entropy, Receptors, Antigen, T-Cell, Protein Data Bank (RCSB PDB), Immunoglobulins, Surface Plasmon Resonance, Conformational entropy, Complementarity Determining Regions, Protein Structure, Secondary, Amino acid, Affinity maturation, Crystallography, Structural Biology, Side chain, Entropy (information theory), Databases, Protein, Molecular Biology, Protein secondary structure, Protein Binding
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المؤلفون: Dipa Patel, Qinwei Zhou, Aiping Zhu, Kris Persaud, Tim Blanc, Marshall Snavely, Dale L. Ludwig, Paul Balderes, Anthony Pennello, Yang Shen, David Surguladze, Yun Kenneth Kang, Stanley Ng, Lin Zeng, Sagit Hindi, Amtul Bari
المصدر: mAbs
مصطلحات موضوعية: Hot Temperature, Immunology, Plasma protein binding, CHO Cells, Immunoglobulin light chain, Immunoglobulin G, lambda light chain, Serine, serine, Cricetulus, Cricetinae, Report, antibody, Animals, Humans, Immunology and Allergy, Amino Acid Sequence, Cysteine, Cytotoxicity, stability and serine deletion, Antibody-dependent cell-mediated cytotoxicity, biology, Chemistry, Protein Stability, IgG1, Lc, Antibody-Dependent Cell Cytotoxicity, Antibodies, Monoclonal, IgG1λ, light chain, HEK293 Cells, Biochemistry, Mutation, biology.protein, Biophysics, Mutagenesis, Site-Directed, Immunoglobulin Light Chains, disulfide bond, Antibody, Protein Binding