المؤلفون: Valeria Marrocco, Tuan Tran, Siying Zhu, Seung Hyuk Choi, Ana M. Gamo, Sijia Li, Qiangwei Fu, Marta Diez Cunado, Jason Roland, Mitch Hull, Van Nguyen-Tran, Sean Joseph, Arnab K. Chatterjee, Nikki Rogers, Matthew S. Tremblay, Weijun Shen

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3983-3993 (2021)

مصطلحات موضوعية: β cells, Unfolded protein response, Small molecules, Protein folding, Endoplasmic reticulum, Chaperones, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383521001842; https://doaj.org/toc/2211-3835

URL الوصول: https://doaj.org/article/aea36db9b3d54981b52e7e072f989c15

المؤلفون: Siying Zhu, Matthew S. Tremblay, Sean B. Joseph, Seung Hyuk Choi, Mitch Hull, Weijun Shen, Valeria Marrocco, Sijia Li, Marta Diez Cunado, Ana M. Gamo, Tuan Tran, Jason Roland, Arnab K. Chatterjee, Qiangwei Fu, Van Nguyen-Tran, Nikki Rogers

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3983-3993 (2021)

مصطلحات موضوعية: TG, thapsigargin, Cell signaling, ATF4, activating transcription factor 4, IKKβ, inhibitor of nuclear factor kappa-B kinase subunit beta, PERK, PKR-like ER kinase, XBP1, X-box-binding protein 1, OGTT, oral glucose tolerance test, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, Unfolded protein response, 0302 clinical medicine, UPR, unfolded protein response, GLuc, Gaussia luciferase, Chaperones, Protein biosynthesis, IL1β, interleukin 1β, General Pharmacology, Toxicology and Pharmaceutics, uHTS, ultra-high throughput screening, IRE1, inositol requiring enzyme 1α/β, 0303 health sciences, ASGR, asialoglycoprotein receptor 1, biology, Chemistry, Small molecules, Diabetes, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, ATF6, activating transcription factor 6α/β, β cells, i.p., intraperitoneal, Cell biology, Liver, 030220 oncology & carcinogenesis, T1/2D, type1/2 diabetes, Tm, tunicamycin, Protein folding, Original Article, ER stress, NASH, nonalcoholic steatohepatitis, INFγ, interferon gamma, TNFα, tumor necrosis factor alpha, RM1-950, GRPRP94, glucose-regulated protein 94, ER, endoplasmic reticulum, 03 medical and health sciences, SP1/2, serine protease1/2, GRP78, 78-kDa glucose-regulated protein, BID, twice a day, Pancreas, 030304 developmental biology, Reporter gene, Nod, non-obese diabetic, Activator (genetics), Endoplasmic reticulum, Metabolic diseases, Chaperone (protein), EGFP-VSVG, enhanced green fluorescence protein-vesicular stomatitis virus ts045 G protein, GSIS, glucose stimulated insulin secretion, biology.protein, Asialoglycoprotein receptor, Therapeutics. Pharmacology, CLuc, Cypridina luciferase, ERP72, endoplasmic reticulum proteins 72

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c176a631b2a5bf8251732009aad27d09
http://europepmc.org/articles/PMC8727761