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1دورية أكاديمية
المؤلفون: Marloes M. Oosterhof, Louis Coussement, Alienke van Pijkeren, Marcel Kwiatkowski, Martijn R. H. Zwinderman, Frank J. Dekker, Tim de Meyer, Vera A. Reitsema, Rainer Bischoff, Victor Guryev, Hjalmar R. Bouma, Rob H. Henning, Marianne G. Rots
المصدر: Epigenetics Communications, Vol 4, Iss 1, Pp 1-14 (2024)
مصطلحات موضوعية: HDAC, HAT, RNA sequencing, Epigenetics, Histone acetylation, WGBS, Genetics, QH426-470
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2730-7034
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2دورية أكاديمية
المؤلفون: Martijn R. H. Zwinderman, Sander de Weerd, Frank J. Dekker
المصدر: Epigenomes, Vol 3, Iss 3, p 19 (2019)
مصطلحات موضوعية: asthma, COPD, inflammation, NF-κB, HDAC, acetylation, post translational modification (PTM), inhibitor, drug design, co-repressor complex, review, Genetics, QH426-470, Biotechnology, TP248.13-248.65
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Fangyuan Cao, Martijn R. H. Zwinderman, Frank J. Dekker
المصدر: Molecules, Vol 23, Iss 3, p 551 (2018)
مصطلحات موضوعية: histone deacetylase 3 (HDAC3), selective, drug discovery, inhibitor, isoenzyme, Organic chemistry, QD241-441
وصف الملف: electronic resource
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المؤلفون: Martijn R. H. Zwinderman, Peter M. Lansdorp, Marcel A. T. M. van Vugt, Petra E van der Wouden, Frank J. Dekker, Victor Guryev, Diana C.J. Spierings, Thamar Jessurun Lobo
المساهمون: Chemical and Pharmaceutical Biology, Stem Cell Aging Leukemia and Lymphoma (SALL), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Groningen Research Institute for Asthma and COPD (GRIAC), Medicinal Chemistry and Bioanalysis (MCB), Biopharmaceuticals, Discovery, Design and Delivery (BDDD)
المصدر: ACS Chemical Biology
ACS chemical biology, 16(11), 2193-2201. AMER CHEMICAL SOCمصطلحات موضوعية: DNA Replication, Cell Cycle Proteins, Ataxia Telangiectasia Mutated Proteins, Biochemistry, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Stress, Physiological, BINDING, Humans, Hydroxyurea, Sister chromatids, HELICASE, Replication protein A, Polymerase, 030304 developmental biology, DAMAGE, 0303 health sciences, biology, Chemistry, DNA replication, Articles, General Medicine, Processivity, Chromatin, Cell biology, ATR, Gene Expression Regulation, Replication Initiation, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Tumor Suppressor Protein p53, DNA
وصف الملف: application/pdf
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المؤلفون: Peter M. Lansdorp, van Vugt Ma, Frank J. Dekker, Guryev, Van der Wouden P, Diana C.J. Spierings, Jessurun Lobo T, Martijn R. H. Zwinderman
مصطلحات موضوعية: chemistry.chemical_compound, Histone, biology, Replication Initiation, Chemistry, biology.protein, DNA replication, Sister chromatids, Processivity, Deposition (chemistry), Polymerase, DNA, Cell biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c2dfbb2c315193f8cfd94bf8cb736845
https://doi.org/10.1101/2021.04.20.440573 -
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المؤلفون: Martijn R. H. Zwinderman
المساهمون: Dekker, Frank, Haisma, Hidde, Chemical and Pharmaceutical Biology
مصطلحات موضوعية: Genetics, Inheritance (object-oriented programming), Histone, biology, biology.protein
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3eff95b9e62061ce0b7902628a4f65d
https://research.rug.nl/en/publications/0d30d677-b630-4cf2-8ed4-a4684d6c8e8f -
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المؤلفون: Frank J. Dekker, Sander de Weerd, Martijn R. H. Zwinderman
المصدر: Epigenomes
Epigenomes, Vol 3, Iss 3, p 19 (2019)مصطلحات موضوعية: 0301 basic medicine, COREPRESSOR COMPLEX, Health, Toxicology and Mutagenesis, NF-KAPPA-B, lcsh:Medicine, Biochemistry, NF-κB, chemistry.chemical_compound, 0302 clinical medicine, HDAC, lcsh:QH301-705.5, COPD, biology, GENE-EXPRESSION PROGRAM, post translational modification (PTM), NF-kappa B, HISTONE DEACETYLASE INHIBITORS, PROSTATE-CANCER, inhibitor, CORTICOSTEROID RESISTANCE, Histone, 030220 oncology & carcinogenesis, medicine.symptom, GLUCOCORTICOID-RECEPTOR-BETA, STRUCTURAL BASIS, drug design, review, Pulmonary disease, Inflammation, Biochemistry, Genetics and Molecular Biology (miscellaneous), co-repressor complex, 03 medical and health sciences, Genetics, medicine, BREAST-CANCER, Asthma, acetylation, business.industry, lcsh:R, asthma, medicine.disease, NFKB1, 030104 developmental biology, TRANSCRIPTIONAL REPRESSION, chemistry, lcsh:Biology (General), Acetylation, inflammation, biology.protein, Cancer research, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5edcacd094ca3c180ab844661a2b672
https://hdl.handle.net/11370/36793d47-b49f-426f-8696-9ddec551cc4d -
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المؤلفون: Petra E. Ettema, Frank J. Dekker, Martijn R. H. Zwinderman, Wim J. Quax, Ronald van Merkerk, Fangyuan Cao
المساهمون: Chemical and Pharmaceutical Biology, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Nanotechnology and Biophysics in Medicine (NANOBIOMED), Medicinal Chemistry and Bioanalysis (MCB)
المصدر: European Journal of Medicinal Chemistry, 177, 457-466. ELSEVIER MASSON, CORPORATION OFFICE
مصطلحات موضوعية: Cell, Gene Expression, Histone Deacetylase 2, Nitric Oxide Synthase Type II, Histone Deacetylase 1, 01 natural sciences, chemistry.chemical_compound, Mice, Catalytic Domain, Drug Discovery, Gene expression, Anilides, 0303 health sciences, biology, Chemistry, Drug discovery, Entinostat, Stereoisomerism, General Medicine, Interleukin-10, Molecular Docking Simulation, HISTONE DEACETYLASE HDAC, medicine.anatomical_structure, Histone, Benzamides, medicine.symptom, Protein Binding, Gene isoform, Inflammation, Histone Deacetylases, 03 medical and health sciences, Structure-Activity Relationship, medicine, Animals, Humans, 030304 developmental biology, Pharmacology, 010405 organic chemistry, Interleukin-6, Tumor Necrosis Factor-alpha, Macrophages, Organic Chemistry, Cancer, NF-kappa B p50 Subunit, medicine.disease, 0104 chemical sciences, Histone Deacetylase Inhibitors, RAW 264.7 Cells, Cancer research, biology.protein
وصف الملف: application/pdf
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المؤلفون: Siwei Chen, Manon Aïssi, Deng Chen, Frank J. Dekker, Hidde J. Haisma, Dominik Kiemel, Anouk La Rose, Fangyuan Cao, Martijn R. H. Zwinderman, Bin Liu
المساهمون: Chemical and Pharmaceutical Biology, Medicinal Chemistry and Bioanalysis (MCB), Biopharmaceuticals, Discovery, Design and Delivery (BDDD)
المصدر: Nucleic Acids Research, 48(2), 517-532. Oxford University Press
Nucleic Acids Researchمصطلحات موضوعية: DNA End-Joining Repair, Histone acetylation and deacetylation, ACETYLATION, Histone Deacetylase 2, RECOMBINATION, Histone Deacetylase 1, CHROMATIN-STRUCTURE, Histones, Gene Knockout Techniques, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Chemical Biology and Nucleic Acid Chemistry, Genome editing, CRISPR-Associated Protein 9, Genetics, Humans, CRISPR, TRANSCRIPTION, CAS9, SPECIFICITY, 030304 developmental biology, Gene Editing, 0303 health sciences, Transcription activator-like effector nuclease, SITES, biology, Cas9, Histone deacetylase 2, DNA, Chromatin, Cell biology, Histone Deacetylase Inhibitors, Histone, chemistry, 030220 oncology & carcinogenesis, BACTERIA, biology.protein, CRISPR-Cas Systems, SYSTEM
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fe8fa74f19d11313c7519f17540dcf
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المؤلفون: Alexander Dömling, Ykelien L. Boersma, Frank J. Dekker, Nikolaos Eleftheriadis, Magdalena Wójcik, Martijn R. H. Zwinderman
المساهمون: Chemical and Pharmaceutical Biology, Molecular Biophysics, Drug Design, Medicinal Chemistry and Bioanalysis (MCB), Biopharmaceuticals, Discovery, Design and Delivery (BDDD)
المصدر: European Journal of Medicinal Chemistry, 161, 93-100. ELSEVIER MASSON, CORPORATION OFFICE
مصطلحات موضوعية: Streptococcus pyogenes, PROTEINS, 15-LIPOXYGENASE-1, Drug Evaluation, Preclinical, Virulence, Microbial Sensitivity Tests, medicine.disease_cause, 01 natural sciences, Microbiology, 03 medical and health sciences, Structure-Activity Relationship, Antibiotic resistance, Bacterial Proteins, Sortase, Drug Discovery, medicine, Enzyme Inhibitors, 030304 developmental biology, Pharmacology, 0303 health sciences, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Pathogenic bacteria, General Medicine, Antimicrobial, biology.organism_classification, Aminoacyltransferases, 0104 chemical sciences, Anti-Bacterial Agents, Cysteine Endopeptidases, Kinetics, TARGET, Sortase A, Drug Design, Bacteria, PATHOGENESIS
وصف الملف: application/pdf
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