المؤلفون: Bruno Sopko, Gracian Tejral, Guissepe Bitti, Marianna Abate, Martina Medvedikova, Marian Hajduch, Jan Chloupek, Jolana Fajmonova, Misa Skoric, Evzen Amler, Tomas Erban

المصدر: ACS Omega, Vol 6, Iss 23, Pp 14848-14857 (2021)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2470-1343

URL الوصول: https://doaj.org/article/0a77d557d8aa4c80b3878c92ebb7c07b

المؤلفون: Martina Medvedíková, Václav Ranc, Ján Vančo, Zdeněk Trávníček, Pavel Anzenbacher

المصدر: Pharmaceutics, Vol 15, Iss 4, p 1314 (2023)

مصطلحات موضوعية: copper(II) complexes, quinolinonato derivatives, cytochrome P450, isothermal titration calorimetry, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/4/1314; https://doaj.org/toc/1999-4923

URL الوصول: https://doaj.org/article/3f0b4d22e590414d9dd82aed747689e3

المؤلفون: Jiří Hodoň, Ivo Frydrych, Zdeňka Trhlíková, Jan Pokorný, Lucie Borková, Sandra Benická, Martin Vlk, Barbora Lišková, Agáta Kubíčková, Martina Medvedíková, Martin Pisár, Jan Šarek, Viswanath Das, Anna Ligasová, Karel Koberna, Petr Džubák, Marián Hajdúch, Milan Urban

المصدر: European journal of medicinal chemistry. 243

مصطلحات موضوعية: Pharmacology, Membrane Potential, Mitochondrial, Pyridines, Organic Chemistry, Antineoplastic Agents, General Medicine, Antineoplastic Agents, Phytogenic, Triterpenes, Drug Resistance, Neoplasm, Pyrazines, Cell Line, Tumor, Drug Discovery, Humans, Prodrugs, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac86c8ad10d87acca5c19bd417f0f70
https://pubmed.ncbi.nlm.nih.gov/36174412

المؤلفون: Jan Chloupek, Marian Hajduch, Martina Medvedíková, Guissepe Bitti, Bruno Sopko, Marianna Abate, Evzen Amler, Gracian Tejral, Tomas Erban, Jolana Fajmonova, Misa Skoric

المصدر: ACS Omega, Vol 6, Iss 23, Pp 14848-14857 (2021)
ACS Omega

مصطلحات موضوعية: Cell growth, General Chemical Engineering, General Chemistry, Pharmacology, Sperm, Article, In vitro, Eukaryotic translation elongation factor 1 alpha 1, chemistry.chemical_compound, Chemistry, chemistry, In vivo, Glyphosate, Protein biosynthesis, Shikimate pathway, QD1-999

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a2857e39850ffc16940fc0209a2e7e
https://doaj.org/article/0a77d557d8aa4c80b3878c92ebb7c07b

المؤلفون: Pavla Perlíková, Marian Hajduch, Blanka Klepetářová, Martina Medvedíková, Nemanja Milisavljevic, Helena Mertlíková-Kaiserová, Petr Džubák, Barbora Lišková, Jana Trylčová, Eva Tloušťová, Radek Pohl, Michal Tichý, Michal Hocek, Ondřej Hodek, Lucia Veselovská, Soňa Gurská, Natálie Kudlová

المصدر: Chemistry – A European Journal. 26:13002-13015

مصطلحات موضوعية: Glycosylation, Pyrimidine, 010405 organic chemistry, Stereochemistry, Organic Chemistry, Total synthesis, Antineoplastic Agents, General Chemistry, 010402 general chemistry, Antiviral Agents, 01 natural sciences, Catalysis, 0104 chemical sciences, Structure-Activity Relationship, chemistry.chemical_compound, chemistry, Nucleophile, Purines, Pyridine, Ribonucleosides, Derivatization, Selectivity, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc07fdfb9d5d82341afc0bcd299b3771
https://doi.org/10.1002/chem.202001124

المؤلفون: Josef Srovnal Ed. ), Anna Janošťáková, Viswanath Das, Natálie Kudlová, Jana Stránská, Renata Buriánová, Jana Kotulová, Ermin Schadich, Martin Ondra, Agáta Kubíčková, Soňa Gurská, Pavla Flodrová, Patrik Flodr, Daniela Kurfürstová, Gabriela Kořínková, Mariam Gachechiladze, Tereza Buchtová, Martin Mistrík, Radek Trojanec, Zuzana Šporiková, Jiří Řehulka, Anna Ligasová, Karel Koberna, Jarmila Stanková, Ivo Frydrych, Khushboo Agrawal, Matthew Lacey, Zdeněk Škrott, Vlastimil Mašek, Martina Medvedíková, Ján Gurský, Petr Džubák, Juan B. De Sanctis, Lenka Hrubá, Jana Václavková, Dušan Holub, Tomáš Oždian, Martina Jakoubková, Miloš Petřík, Zbyněk Nový, Narendran Annadurai, Alejandro Carazo, Barbora Lišková, Vladimíra Koudeláková, Vaishali Uniyal, Jiří Drábek, Zuzana Macečková, Hanuš Slavík, Josef Srovnal, Alona Řehulková, Karolína Bartáková, Rastislav Slavkovský

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::81f58b62c89602863dbe4640e595f609
https://doi.org/10.5507/lf.22.24460499

المؤلفون: Soňa Gurská, Bohumír Grüner, Jana Štěpánková, Marian Hajduch, K. Pospisilova, Alice Nova, Pavlína Řezáčová, Václav Šícha, Milan Fábry, Vlastimil Mašek, Petr Džubák, Stanislava Matějková, Jan Nekvinda, Petr Pachl, Josef Holub, Viswanath Das, Jiří Brynda, Barbora Lišková, Martina Medvedíková, Vlastimil Král, M. Kugler

المصدر: Journal of Medicinal Chemistry. 62:9560-9575

مصطلحات موضوعية: Models, Molecular, Gene isoform, Mice, Catalytic Domain, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Doxorubicin, Boranes, Carbonic Anhydrase IX, Carbonic Anhydrase Inhibitors, chemistry.chemical_classification, biology, Chemistry, Active site, Biological Transport, Drug Synergism, Amides, Xenograft Model Antitumor Assays, Transmembrane protein, Cytosol, Enzyme, Cell culture, Drug Design, biology.protein, Cancer research, Molecular Medicine, Syngenic, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ed48e61de08139656b184ea62fe554
https://doi.org/10.1021/acs.jmedchem.9b00945

المؤلفون: Dominik Vítek, Marek Zatloukal, Jiří Voller, Marian Hajduch, Miroslav Strnad, Beata Monfort, Libor Havlíček, Veronika Ručilová, Alena Kadlecová, Prashant Khirsariya, Gabriel Gonzalez, Kamil Paruch, Miroslav Soural, Barbara Maková, Václav Mik, Martina Medvedíková, Barbora Lišková, Benoît D'Autréaux, Zoila Gándara Barreiro

المساهمون: Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Stress Oxydatif et Cancer (SOC), Département Biologie Cellulaire (BioCell), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), ANR-17-CE11-0021,FRATAXUR,Bases moléculaires et structurales de la biogenèse des centres fer-soufre permettant d'élucider la fonction moléculaire de la frataxine(2017)

المصدر: Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2021, 33, pp.115993. ⟨10.1016/j.bmc.2021.115993⟩
Bioorganic and Medicinal Chemistry, 2021, 33, pp.115993. ⟨10.1016/j.bmc.2021.115993⟩

مصطلحات موضوعية: Purine, Cell Survival, [SDV]Life Sciences [q-bio], Clinical Biochemistry, Cytokinin, Pharmaceutical Science, medicine.disease_cause, 01 natural sciences, Biochemistry, Neuroprotection, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, medicine, Humans, bioisostery – Friedreich́s ataxia, Molecular Biology, Cells, Cultured, Mitoprotection – familial dysautonomia, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Glutathione, Kinetin, In vitro, 0104 chemical sciences, 3. Good health, 010404 medicinal & biomolecular chemistry, Oxidative Stress, Mechanism of action, Cytoprotection, Purines, Molecular Medicine, medicine.symptom, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd9c8d687881f84bf5a1fe1e68f285b
https://pubmed.ncbi.nlm.nih.gov/33497938

المؤلفون: Viswanath Das, Jan Nekvinda, Jiří Brynda, K. Pospisilova, Marian Hajduch, Stanislava Matějková, Jana Dvořanová, Martina Medvedíková, Josef Holub, Soňa Gurská, Bohumír Grüner, Miroslav Havránek, Vlastimil Král, M. Kugler, Barbora Liskova, Pavlína Řezáčová, Suzan El Anwar, Václav Šícha, Milan Fábry, Petr Džubák

المصدر: European journal of medicinal chemistry. 200

مصطلحات موضوعية: Cell, Antineoplastic Agents, Breast Neoplasms, Mice, SCID, 01 natural sciences, 03 medical and health sciences, Mice, Structure-Activity Relationship, Dogs, Antigens, Neoplasm, Drug Discovery, medicine, Animals, Humans, Doxorubicin, Cytotoxicity, Carbonic Anhydrase IX, Carbonic Anhydrase Inhibitors, Cells, Cultured, 030304 developmental biology, ADME, Cell Proliferation, Pharmacology, chemistry.chemical_classification, 0303 health sciences, Mice, Inbred BALB C, Sulfonamides, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Active site, General Medicine, Neoplasms, Experimental, Recombinant Proteins, 0104 chemical sciences, Enzyme, medicine.anatomical_structure, chemistry, Biochemistry, Cell culture, biology.protein, Carborane, Drug Screening Assays, Antitumor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81bb479421d4d79625909803ff9b18a6
https://pubmed.ncbi.nlm.nih.gov/32505851

المؤلفون: Nikola Jakubcová, Richard Adamek, Barbora Lišková, Marian Hajduch, Lucie Borkova, Ivo Frydrych, Milan Urban, Martina Medvedíková, Soňa Gurská

المصدر: European Journal of Medicinal Chemistry. 185:111806

مصطلحات موضوعية: Antineoplastic Agents, Apoptosis, 01 natural sciences, Structure-Activity Relationship, 03 medical and health sciences, Microsomes, Drug Discovery, medicine, Humans, Cytotoxic T cell, Oleanolic Acid, Cytotoxicity, IC50, Cells, Cultured, Cell Proliferation, 030304 developmental biology, Membrane Potential, Mitochondrial, Pharmacology, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, Terpenes, 010405 organic chemistry, Chemistry, Organic Chemistry, Cancer, Biological activity, General Medicine, Fibroblasts, medicine.disease, Triterpenes, 0104 chemical sciences, Thiazoles, Biochemistry, Cell culture, Drug Screening Assays, Antitumor, K562 cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ecf70db912e61395cb7cf0e636bd83
https://doi.org/10.1016/j.ejmech.2019.111806