يعرض 1 - 10 نتائج من 133 نتيجة بحث عن '"Martine, Schmitt"', وقت الاستعلام: 0.91s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Coumarin Derivatives Exert Anti-Lung Cancer Activity by Inhibition of Epithelial–Mesenchymal Transition and Migration in A549 Cells

    المؤلفون: Rodrigo Santos Aquino de Araújo, Julianderson de Oliveira dos Santos Carmo, Simone Lara de Omena Silva, Camila Radelley Azevedo Costa da Silva, Tayhana Priscila Medeiros Souza, Natália Barbosa de Mélo, Jean-Jacques Bourguignon, Martine Schmitt, Thiago Mendonça de Aquino, Renato Santos Rodarte, Ricardo Olímpio de Moura, José Maria Barbosa Filho, Emiliano Barreto, Francisco Jaime Bezerra Mendonça-Junior

    المصدر: Pharmaceuticals, Vol 15, Iss 1, p 104 (2022)

    مصطلحات موضوعية: anticancer activity, lung cancer, non-small-cell lung cancer, epithelial–mesenchymal transition, metastasis, coumarin derivative, Medicine, Pharmacy and materia medica, RS1-441

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/1424-8247/15/1/104; https://doaj.org/toc/1424-8247

    URL الوصول: https://doaj.org/article/3495e3abf91948e2ace37a27b7d62bbc

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  2. 2
    دورية أكاديمية
    Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice

    المؤلفون: Cyril Rivat, Chamroeun Sar, Ilana Mechaly, Jean-Philippe Leyris, Lucie Diouloufet, Corinne Sonrier, Yann Philipson, Olivier Lucas, Sylvie Mallié, Antoine Jouvenel, Adrien Tassou, Henri Haton, Stéphanie Venteo, Jean-Philippe Pin, Eric Trinquet, Fabienne Charrier-Savournin, Alexandre Mezghrani, Willy Joly, Julie Mion, Martine Schmitt, Alexandre Pattyn, Frédéric Marmigère, Pierre Sokoloff, Patrick Carroll, Didier Rognan, Jean Valmier

    المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

    مصطلحات موضوعية: Science

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2041-1723

    URL الوصول: https://doaj.org/article/87fd7efd827f43ad990381c8a9541b42

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  3. 3
    دورية أكاديمية
    A phenol-enriched cuticle is ancestral to lignin evolution in land plants

    المؤلفون: Hugues Renault, Annette Alber, Nelly A. Horst, Alexandra Basilio Lopes, Eric A. Fich, Lucie Kriegshauser, Gertrud Wiedemann, Pascaline Ullmann, Laurence Herrgott, Mathieu Erhardt, Emmanuelle Pineau, Jürgen Ehlting, Martine Schmitt, Jocelyn K. C. Rose, Ralf Reski, Danièle Werck-Reichhart

    المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)

    مصطلحات موضوعية: Science

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2041-1723

    URL الوصول: https://doaj.org/article/867ea0f682b44076add9006ed0d9b915

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  4. 4
    دورية أكاديمية
    Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model

    المؤلفون: Maud Bollenbach, Simona Nemska, Patrick Wagner, Guillaume Camelin, François Daubeuf, Adeline Obrecht, Pascal Villa, Didier Rognan, Frédéric Bihel, Jean-Jacques Bourguignon, Martine Schmitt, Nelly Frossard

    المصدر: Molecules, Vol 26, Iss 2, p 391 (2021)

    مصطلحات موضوعية: Pyridine-2-yl guanidine, MSK1, kinase inhibitors, inflammation, asthma, Organic chemistry, QD241-441

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/1420-3049/26/2/391; https://doaj.org/toc/1420-3049

    URL الوصول: https://doaj.org/article/be77ee75372d43f0ba33a96af0aa47d9

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  5. 5
    Diastereoselective Synthesis of Nonplanar 3-Amino-1,2,4-oxadiazine Scaffold: Structure Revision of Alchornedine

    المؤلفون: Shuang-Qi Tang, Frédéric Bihel, Delphine Garnier, Martine Schmitt, Jacques Bricard, Séverine Schneider, Maeva Leloire, Julie Mohr, Patrick Gizzi

    المساهمون: Laboratoire d'Innovation Thérapeutique (LIT), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC), Unité de Catalyse et Chimie du Solide - UMR 8181 (UCCS), Centrale Lille Institut (CLIL)-Université d'Artois (UA)-Centrale Lille-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Lille, Plate-forme de chimie biologique intégrative de Strasbourg (PCBiS), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), PhD grant for S-Q T, China Scholarship Council (201608310124), Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université d'Artois (UA)-Centrale Lille-Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: Journal of Organic Chemistry
    Journal of Organic Chemistry, American Chemical Society, In press, ⟨10.1021/acs.joc.0c01764⟩
    Journal of Organic Chemistry, In press, ⟨10.1021/acs.joc.0c01764⟩

    مصطلحات موضوعية: Steric effects, Scaffold, Natural product, [CHIM.ORGA]Chemical Sciences/Organic chemistry, 010405 organic chemistry, Reducing agent, Stereochemistry, Organic Chemistry, 010402 general chemistry, Ring (chemistry), 01 natural sciences, 3. Good health, 0104 chemical sciences, chemistry.chemical_compound, chemistry, [CHIM]Chemical Sciences, Moiety, Mitsunobu reaction, Guanidine

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b72e269e2f2c2b67b432e748bbfa018
    https://doi.org/10.1021/acs.joc.0c01764

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  6. 6
    POxAP Precatalysts and the Negishi Cross-Coupling Reaction

    المؤلفون: Shuang-Qi Tang, Frédéric Bihel, Martine Schmitt

    المساهمون: Laboratoire d'Innovation Thérapeutique (LIT), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC)

    المصدر: SYNTHESIS
    SYNTHESIS, Georg Thieme Verlag, 2019, 52 (01), pp.51-59. ⟨10.1055/s-0039-1690728⟩

    مصطلحات موضوعية: organozinc, organohalides, chemistry.chemical_element, 010402 general chemistry, 01 natural sciences, Catalysis, Coupling reaction, chemistry.chemical_compound, Negishi cross-coupling, XPhos, [CHIM]Chemical Sciences, organozinc reagents, Negishi cross-coupling reaction, POxAP, 010405 organic chemistry, Chemistry, Negishi coupling, Organic Chemistry, palladium, Combinatorial chemistry, 0104 chemical sciences, Reagent, precatalyst, organohalide, Palladium

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57eaa008baea8036276d2818c901fe4c
    https://doi.org/10.1055/s-0039-1690728

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  7. 7
    Identification of an N -acylated- D Arg-Leu-NH 2 Dipeptide as a Highly Selective Neuropeptide FF1 Receptor Antagonist That Potently Prevents Opioid-Induced Hyperalgesia

    المؤلفون: Patrick Gizzi, Brigitte Ilien, Raphaëlle Quillet, Valérie Kugler, Frédéric Simonin, Valérie Simonneaux, Martine Schmitt, Frédéric Bihel, Khadija Elhabazi, Valérie Utard, Jo B. Henningsen, Armand Drieu la Rochelle, Séverine Schneider

    المساهمون: Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS), Laboratoire d'Innovation Thérapeutique (LIT), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC), Institut des Neurosciences Cellulaires et Intégratives (INCI), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Plate-forme de chimie biologique intégrative de Strasbourg (PCBiS), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), ANR-17-EURE-0022,EURIDOL,Ecole Universitaire de Recherche Interdisciplinaire sur la Douleur(2017), ANR-10-LABX-0034,Medalis,Medalis Drug Discovery Center(2010)

    المصدر: Journal of Medicinal Chemistry
    Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (11), pp.7555-7564. ⟨10.1021/acs.jmedchem.1c00256⟩

    مصطلحات موضوعية: 0303 health sciences, Chemistry, medicine.drug_class, Antagonist, Chronic pain, Neuropeptide, Pharmacology, Receptor antagonist, medicine.disease, 01 natural sciences, 3. Good health, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Drug Discovery, Hyperalgesia, medicine, Molecular Medicine, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Neuropeptide FF, medicine.symptom, Receptor, Opioid-induced hyperalgesia, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc033340f680288639fd0c6e10518c96
    https://hal.archives-ouvertes.fr/hal-03363456/document

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  8. 8
    Identification of an

    المؤلفون: Raphaëlle, Quillet, Séverine, Schneider, Valérie, Utard, Armand, Drieu la Rochelle, Khadija, Elhabazi, Jo Beldring, Henningsen, Patrick, Gizzi, Martine, Schmitt, Valérie, Kugler, Valérie, Simonneaux, Brigitte, Ilien, Frédéric, Simonin, Frédéric, Bihel

    المصدر: Journal of medicinal chemistry. 64(11)

    مصطلحات موضوعية: Male, Receptors, Neuropeptide, Neuropeptides, Dipeptides, Luteinizing Hormone, Analgesics, Opioid, Fentanyl, Mice, Inbred C57BL, Mice, Structure-Activity Relationship, Hyperalgesia, Cricetinae, Receptors, Opioid, Animals, Humans, Protein Isoforms, Female, Half-Life

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::1e529d376378670e47de2cac05128375
    https://pubmed.ncbi.nlm.nih.gov/34008968

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  9. 9
    Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes

    المؤلفون: Thiago Mendonça de Aquino, Raiza Raianne Luz Rodrigues, Magna Suzana Alexandre-Moreira, Johnnatan D. de Freitas, Paulo Henrique Barcellos França, Jean-Jacques Bourguignon, Morgana Vital de Araújo, Mario R. Meneghetti, Mariana da Silva Santos, Paulo Fernando da Silva Santos-Júnior, Klinger Antonio da Franca Rodrigues, Pedro G. V. Aquino, Edeildo Ferreira da Silva-Júnior, Jacques Bricard, Martine Schmitt, João Xavier de Araújo-Júnior, Érica E E S Rodrigues, Aline Cavalcanti de Queiroz, Igor José Dos Santos Nascimento

    المساهمون: Laboratoire d'Innovation Thérapeutique (LIT), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC)

    المصدر: Medicinal Chemistry
    Medicinal Chemistry, Bentham Science Publishers, In press, ⟨10.2174/1573406417666210216154428⟩

    مصطلحات موضوعية: medicine.drug_class, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Pharmacology, 01 natural sciences, 03 medical and health sciences, thiosemicarbazone, Drug Discovery, medicine, antileishmanial activity, Amastigote, Trypanosoma cruzi, 030304 developmental biology, 0303 health sciences, biology, Chemistry, Leishmania chagasi, structure-activity relationship, Biological activity, Aminoguanidine hydrazone, molecular docking, Leishmania, biology.organism_classification, medicine.disease, 3. Good health, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Visceral leishmaniasis, Antiprotozoal, Pentamidine, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42eea8176730925daef2211b49190258
    https://hal.archives-ouvertes.fr/hal-03407968

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  10. 10
    Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model

    المؤلفون: François Daubeuf, Patrick Wagner, Frédéric Bihel, Martine Schmitt, Guillaume Camelin, Adeline Obrecht, Didier Rognan, Nelly Frossard, Simona Nemska, Jean-Jacques Bourguignon, Maud Bollenbach, Pascal Villa

    المساهمون: Laboratoire d'Innovation Thérapeutique (LIT), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC)

    المصدر: Molecules, Vol 26, Iss 391, p 391 (2021)
    Molecules
    Volume 26
    Issue 2
    Molecules, MDPI, 2021, 26 (2), pp.391. ⟨10.3390/molecules26020391⟩

    مصطلحات موضوعية: MSK1, Pharmaceutical Science, Inflammation, Pharmacology, Guanidines, Ribosomal Protein S6 Kinases, 90-kDa, 01 natural sciences, Article, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, lcsh:Organic chemistry, Psoriasis, Drug Discovery, medicine, Humans, [CHIM]Chemical Sciences, kinase inhibitors, Physical and Theoretical Chemistry, Guanidine, Protein Kinase Inhibitors, Transcription factor, Cells, Cultured, 030304 developmental biology, Asthma, 0303 health sciences, Molecular Structure, biology, 010405 organic chemistry, Chemistry, Kinase, Organic Chemistry, asthma, medicine.disease, Pyridine-2-yl guanidine, In vitro, 0104 chemical sciences, 3. Good health, Chemistry (miscellaneous), inflammation, Drug Design, Mitogen-activated protein kinase, biology.protein, Molecular Medicine, medicine.symptom

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aceeb21fe0934551e0f90fc0ed2db523
    https://www.mdpi.com/1420-3049/26/2/391

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