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المؤلفون: Lauren E Fitch, Vincent M. Isabella, Kristin J. Adolfsen, Munira Momin, Teodelinda Mirabella, Adam G Lawrence, James E. Spoonamore, Per Jr Greisen, Andres Abin-Fuentes, Isolde Callihan, Mary Castillo, Lauren Renaud, Carl J Weile, Catherine E Monahan, Lindong Weng, Jay H Konieczka
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communicationsمصطلحات موضوعية: Phenylalanine hydroxylase, Phenylalanine, High-throughput screening, Science, Mutant, General Physics and Astronomy, Biosensing Techniques, Phenylalanine ammonia-lyase, Protein Engineering, medicine.disease_cause, Article, General Biochemistry, Genetics and Molecular Biology, In vivo, Phenylketonurias, Escherichia coli, medicine, Humans, Synthetic biology, Phenylalanine Ammonia-Lyase, chemistry.chemical_classification, Multidisciplinary, biology, Escherichia coli Proteins, fungi, technology, industry, and agriculture, food and beverages, General Chemistry, humanities, Biological Therapy, Enzyme, Biochemistry, chemistry, Cinnamates, biology.protein, Molecular evolution
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2
المؤلفون: Aoife M. Brennan, Larry Blankstein, Mark R. Charbonneau, Mary Castillo, John A. Phillips, Benjamin D. Goodlett, William S. Denney, Caroline B. Kurtz, David A. Wagner, Jerry Vockley, Marja K. Puurunen, Stephanie Sacharow, Vincent M. Isabella, Vasu V. Sethuraman, Richard Riese, Shawn Searle
المصدر: Nature Metabolism. 3:1125-1132
مصطلحات موضوعية: Gastrointestinal tract, business.industry, Endocrinology, Diabetes and Metabolism, Hippuric acid, Phenylalanine, Cell Biology, Phenylalanine ammonia-lyase, Pharmacology, chemistry.chemical_compound, chemistry, Tolerability, Physiology (medical), Pharmacodynamics, Internal Medicine, Medicine, Tyrosine, Adverse effect, business
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المؤلفون: Elaine A. Merrill, Peter J Robinson, Camilla A Mauzy, Heidi G. Coia, Corey Holt, Eric S. Greenwood, Mark R. Charbonneau, Mary Castillo, David Lubkowicz, M. Tyler Nelson
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communicationsمصطلحات موضوعية: Primates, 0301 basic medicine, Phenotypic screening, Phenylalanine, Science, Microfluidics, General Physics and Astronomy, Computational biology, In Vitro Techniques, Biology, Blood phenylalanine, Models, Biological, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Synthetic biology, 0302 clinical medicine, Human gut, In vivo, Lab-On-A-Chip Devices, Phenylketonurias, Escherichia coli, medicine, Animals, Humans, Computer Simulation, Multidisciplinary, Bacteria, Strain (biology), Human gastrointestinal tract, General Chemistry, Gastrointestinal Microbiome, Biomarker (cell), Biological Therapy, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Synthetic Biology, Caco-2 Cells, Genetic Engineering, Metabolic engineering, HT29 Cells, Function (biology)
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المؤلفون: Aoife M. Brennan, Nicholas G. Horvath, William S. Denney, Mary Castillo, Pasquale Cantarella, Mark R. Charbonneau, Marja K. Puurunen
المصدر: Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)مصطلحات موضوعية: Primates, 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, QH301-705.5, Medicine (miscellaneous), Phenylalanine, Pharmacology, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Phenylketonurias, Healthy volunteers, Computational models, Animals, Humans, Medicine, In patient, Biology (General), Gastrointestinal tract, business.industry, Healthy subjects, nutritional and metabolic diseases, Human physiology, Healthy Volunteers, 030104 developmental biology, General Agricultural and Biological Sciences, business, 030217 neurology & neurosurgery
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المؤلفون: Putman Ryan, Carlin Dylan Alexander, Patrick M. Boyle, Silvia Galvan, Michael J. James, Caroline B. Kurtz, Ning Li, Christopher Bergeron, Kolea Zimmerman, Jain Rishi, Lauren Renaud, Mary Castillo, Mylene Perreault, Jian-Rong Gao, Tucker Alex C, Laura Stone, Scott Marr
مصطلحات موضوعية: Probiotic, chemistry.chemical_compound, Biochemistry, chemistry, law, Branched-chain amino acid, law.invention
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9db14f5bda666cb0897ab3cf478b0afc
https://doi.org/10.21203/rs.3.rs-318620/v1 -
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المؤلفون: Paul F. Miller, Mary Castillo, Caroline B. Kurtz, Kip A. West, Philippa J. Reeder, Binh Ha, Adam B. Fisher, Yves Millet, Vincent M. Isabella, Cami Leigh Anderson, David Lubkowicz, Dean Falb, Sarah Rowe, Christopher Bergeron, Sarah E. Guilmain, Ning Li, Munira Momin
المصدر: Nature Biotechnology. 36:857-864
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Biomedical Engineering, Neurotoxicity, Bioengineering, Phenylalanine, Urine, Biology, Pharmacology, medicine.disease_cause, medicine.disease, Applied Microbiology and Biotechnology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Enzyme, chemistry, Pharmacodynamics, medicine, Molecular Medicine, Escherichia coli, Gene, 030217 neurology & neurosurgery, Feces, Biotechnology
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المؤلفون: Mary Castillo, Adam B. Fisher, Paul S. Miller, Starsha Kolodziej, Ning Li, Jose M. Lora, Daniel S. Leventhal, Carey W. Gallant, Anna Sokolovska, Chris Plescia, Kip A. West
المصدر: Cancer Research. 78:LB-131
مصطلحات موضوعية: Cancer Research, Tumor microenvironment, medicine.medical_treatment, T cell, Immunotherapy, Biology, Acquired immune system, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine.anatomical_structure, Immune system, Oncology, chemistry, Antigen, 030220 oncology & carcinogenesis, medicine, Cancer research, Antigen-presenting cell, Kynurenine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2219757d5a0e403292a22db6e6fa84ed
https://doi.org/10.1158/1538-7445.am2018-lb-131 -
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المؤلفون: Mary Castillo, Vincent M. Isabella, Jose M. Lora, Ning Li, Paul S. Miller, Chris Plescia, Kip A. West, Anna Sokolovska, Dan Leventhal, Starsha Kolodziej, Adam B. Fisher
المصدر: Cancer Research. 78:2920-2920
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Tumor microenvironment, Tumor initiation, Biology, Adenosine, In vitro, Immune tolerance, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Immune system, Oncology, chemistry, In vivo, 030220 oncology & carcinogenesis, Cancer research, medicine, Kynurenine, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fc6fc4615c1ee134303ca434ec2b00a1
https://doi.org/10.1158/1538-7445.am2018-2920 -
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المؤلفون: John V. Thomas, Jose M. Lora, Binh Ha, Paul S. Miller, Lauren Renaud, Caroline B. Kurtz, Mary Castillo, Denise Wong, Yves Millet, Yossi Dagon
المصدر: Gastroenterology. 154:S-1078
مصطلحات موضوعية: 0301 basic medicine, Hepatology, Genetically engineered, Gastroenterology, Hyperammonemia, medicine.disease, Microbiology, 03 medical and health sciences, Ammonia, chemistry.chemical_compound, 030104 developmental biology, chemistry, medicine, Urea, Hepatic encephalopathy
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