المؤلفون: Chung, CH, Guthrie, VB, Masica, DL, Tokheim, C, Kang, H, Richmon, J, Agrawal, N, Fakhry, C, Quon, H, Subramaniam, RM, Zuo, Z, Seiwert, T, Chalmers, ZR, Frampton, GM, Ali, SM, Yelensky, R, Stephens, PJ, Miller, VA, Karchin, R, Bishop, JA

المصدر: Annals of Oncology. 26(6)

مصطلحات موضوعية: Rare Diseases, Human Genome, Dental/Oral and Craniofacial Disease, Cancer, Genetics, Infectious Diseases, Clinical Research, Sexually Transmitted Infections, Biotechnology, Good Health and Well Being, Adult, Aged, Aged, 80 and over, Biomarkers, Tumor, Carcinoma, Squamous Cell, Cyclin-Dependent Kinase Inhibitor p16, DNA Copy Number Variations, DNA, Viral, Databases, Genetic, Female, Fixatives, Formaldehyde, Gene Expression Profiling, Genetic Association Studies, Genetic Predisposition to Disease, Head and Neck Neoplasms, High-Throughput Nucleotide Sequencing, Human Papillomavirus DNA Tests, Humans, Immunohistochemistry, In Situ Hybridization, Male, Middle Aged, Mutation, Papillomaviridae, Paraffin Embedding, Phenotype, Predictive Value of Tests, Prognosis, Squamous Cell Carcinoma of Head and Neck, Tissue Fixation, DNA mutation, copy number variation, human papillomavirus, head and neck squamous cell carcinoma, Oncology and Carcinogenesis, Oncology & Carcinogenesis

وصف الملف: application/pdf

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المؤلفون: McLaughlin RT; Genomics Research Center, AbbVie, Redwood City, CA, USA. robert.mclaughlin@abbvie.com., Asthana M; Agricultural and Biological Engineering at Purdue University, West Lafayette, IN, USA., Di Meo M; Johns Hopkins University, Baltimore, MD, USA., Ceccarelli M; Department of Electrical Engineering and Information Technology, University of Naples 'Federico II', Naples, Italy.; Biogem, Instituto di Biologia e Genetica Molecolare, Ariano Irpino, Italy., Jacob HJ; Genomics Research Center, AbbVie, Redwood City, CA, USA., Masica DL; Genomics Research Center, AbbVie, Redwood City, CA, USA. david.masica@abbvie.com.

المصدر: NPJ precision oncology [NPJ Precis Oncol] 2023 Jan 07; Vol. 7 (1), pp. 4. Date of Electronic Publication: 2023 Jan 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE

المؤلفون: Lambert SL; Oncology Early Development., Zhang C; Discovery and Exploratory Statistics., Guo C; Discovery and Exploratory Statistics., Turan T; Genomics Research Center., Masica DL; Genomics Research Center., Englert S; Data and Statistical Sciences, AbbVie Deutschland GmbH & Co KG, Ludwigshafen, Germany., Fang Y; Drug Metabolism, Pharmacokinetics, AbbVie Inc, Redwood City, CA., Sheridan J; Drug Metabolism, Pharmacokinetics, AbbVie Inc, Redwood City, CA., McLaughlin RT; Genomics Research Center., Tribouley C; Oncology Early Development., Vosganian G; Oncology Early Development., Afar D; Oncology Early Development.

المصدر: Journal of immunotherapy (Hagerstown, Md. : 1997) [J Immunother] 2022 Apr 01; Vol. 45 (3), pp. 167-179.

نوع المنشور: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9706083 Publication Model: Print Cited Medium: Internet ISSN: 1537-4513 (Electronic) Linking ISSN: 15249557 NLM ISO Abbreviation: J Immunother Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/therapeutic use , Carcinoma, Non-Small-Cell Lung*/pathology , Head and Neck Neoplasms*/drug therapy , Lung Neoplasms*/genetics, Antibodies, Monoclonal/therapeutic use ; Antibodies, Monoclonal, Humanized ; B7-H1 Antigen ; Biomarkers ; Biomarkers, Tumor/metabolism ; Humans ; Immune Checkpoint Inhibitors ; Squamous Cell Carcinoma of Head and Neck/drug therapy

المؤلفون: Springer S; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA., Masica DL; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Biomedical Engineering, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, MD 21287, USA.; Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD 21287, USA., Dal Molin M; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA., Douville C; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Biomedical Engineering, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, MD 21287, USA.; Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD 21287, USA., Thoburn CJ; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA., Afsari B; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University, Baltimore, MD 21287, USA., Li L; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA., Cohen JD; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Biomedical Engineering, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, MD 21287, USA., Thompson E; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA., Allen PJ; Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA., Klimstra DS; Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA., Schattner MA; Department of Gastroenterology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA., Schmidt CM; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Yip-Schneider M; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Simpson RE; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Fernandez-Del Castillo C; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Mino-Kenudson M; Department of Histopathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Brugge W; Department of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Brand RE; Department of Medicine, University of Pittsburgh, Pittsburgh PA 15213, USA., Singhi AD; Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Scarpa A; ARC-Net Research Centre, University and Hospital Trust of Verona, Verona 37134, Italy.; Department of Pathology and Diagnostics, University and Hospital Trust of Verona, Verona 37134, Italy., Lawlor R; ARC-Net Research Centre, University and Hospital Trust of Verona, Verona 37134, Italy.; Department of Pathology and Diagnostics, University and Hospital Trust of Verona, Verona 37134, Italy., Salvia R; General and Pancreatic Surgery, Pancreas Institute, University and Hospital Trust of Verona, Verona 37134, Italy., Zamboni G; Department of Pathology, Ospedale Sacro Cuore-Don Calabria, Negrar 37024, Italy., Hong SM; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, South Korea., Hwang DW; Hepatobiliary and Pancreas Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, South Korea., Jang JY; Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, South Korea., Kwon W; Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, South Korea., Swan N; Department of Histopathology, St. Vincent's University Hospital, Dublin D04 T6F4, Ireland., Geoghegan J; Department of Surgery, St. Vincent's University Hospital, Dublin D04 T6F4, Ireland., Falconi M; Division of Pancreatic Surgery, Department of Surgery, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy., Crippa S; Division of Pancreatic Surgery, Department of Surgery, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy., Doglioni C; Department of Pathology, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy., Paulino J; Department of Surgery, Centro Hepatobiliopancreático e Transplantação, Hospital Curry Cabral, Lisbon 1050-099, Portugal., Schulick RD; Department of Surgery, University of Colorado, Aurora, CO 80045, USA., Edil BH; Department of Surgery, University of Colorado, Aurora, CO 80045, USA., Park W; Department of Medicine, Stanford University Medical Center, Palo Alto, CA 94304, USA., Yachida S; Department of Hepatobiliary and Pancreatic Surgery, Pathology and Cancer Genomics, National Cancer Center Hospital and National Cancer Center Research Institute, Tokyo 104-0045, Japan., Hijioka S; Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya 464-8681, Japan., van Hooft J; Department of Gastroenterology and Hepatology, Amsterdam Medical Center, Amsterdam 1017 ZX, Netherlands., He J; Department of Surgery, Johns Hopkins University, Baltimore, MD 21287, USA., Weiss MJ; Department of Surgery, Johns Hopkins University, Baltimore, MD 21287, USA., Burkhart R; Department of Surgery, Johns Hopkins University, Baltimore, MD 21287, USA., Makary M; Department of Surgery, Johns Hopkins University, Baltimore, MD 21287, USA., Canto MI; Department of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA., Goggins MG; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA., Ptak J; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA., Dobbyn L; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA., Schaefer J; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA., Sillman N; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA., Popoli M; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA., Klein AP; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University, Baltimore, MD 21287, USA., Tomasetti C; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA. bertvog@gmail.com amlennon@jhmi.edu cwolfga2@jhmi.edu rhruban@jhmi.edu ctomasetti@jhu.edu karchin@jhu.edu.; Department of Biostatistics and Bioinformatics, Johns Hopkins University, Baltimore, MD 21287, USA., Karchin R; Department of Biomedical Engineering, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, MD 21287, USA.; Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA. bertvog@gmail.com amlennon@jhmi.edu cwolfga2@jhmi.edu rhruban@jhmi.edu ctomasetti@jhu.edu karchin@jhu.edu., Papadopoulos N; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA., Kinzler KW; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA., Vogelstein B; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA. bertvog@gmail.com amlennon@jhmi.edu cwolfga2@jhmi.edu rhruban@jhmi.edu ctomasetti@jhu.edu karchin@jhu.edu.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA., Wolfgang CL; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA. bertvog@gmail.com amlennon@jhmi.edu cwolfga2@jhmi.edu rhruban@jhmi.edu ctomasetti@jhu.edu karchin@jhu.edu.; Department of Oncology, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Surgery, Johns Hopkins University, Baltimore, MD 21287, USA., Hruban RH; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University, Baltimore, MD 21287, USA.; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA. bertvog@gmail.com amlennon@jhmi.edu cwolfga2@jhmi.edu rhruban@jhmi.edu ctomasetti@jhu.edu karchin@jhu.edu., Lennon AM; Ludwig Center and Howard Hughes Medical Institute at the Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA. bertvog@gmail.com amlennon@jhmi.edu cwolfga2@jhmi.edu rhruban@jhmi.edu ctomasetti@jhu.edu karchin@jhu.edu.; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Surgery, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Radiology, Johns Hopkins University, Baltimore, MD 21287, USA.

المصدر: Science translational medicine [Sci Transl Med] 2019 Jul 17; Vol. 11 (501).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Algorithms*, Pancreatic Cyst/*diagnosis, Aged ; Female ; Humans ; Machine Learning ; Male ; Middle Aged ; Pancreatic Cyst/genetics ; Pancreatic Cyst/pathology ; Pancreatic Cyst/surgery

المؤلفون: Felsenstein M; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany., Noë M; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Masica DL; Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA., Hosoda W; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Chianchiano P; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Fischer CG; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Lionheart G; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Brosens LAA; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., Pea A; Department of Surgery, University and Hospital Trust of Verona, Verona, Italy., Yu J; Department of Surgery, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Gemenetzis G; Department of Surgery, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Groot VP; Department of Surgery, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands., Makary MA; Department of Surgery, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., He J; Department of Surgery, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Weiss MJ; Department of Surgery, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Cameron JL; Department of Surgery, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Wolfgang CL; Department of Surgery, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Hruban RH; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Roberts NJ; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Karchin R; Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA., Goggins MG; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Wood LD; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

المصدر: Gut [Gut] 2018 Sep; Vol. 67 (9), pp. 1652-1662. Date of Electronic Publication: 2018 Mar 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE

مواضيع طبية MeSH: Biomarkers, Tumor/*genetics , Carcinoma, Pancreatic Ductal/*genetics , Mutation/*genetics , Pancreatic Neoplasms/*genetics, Adenocarcinoma, Mucinous/genetics ; Aged ; Carcinoma, Pancreatic Ductal/diagnosis ; Carcinoma, Pancreatic Ductal/mortality ; Carcinoma, Papillary/genetics ; Chromogranins/genetics ; DNA-Binding Proteins/genetics ; Female ; Follow-Up Studies ; GTP-Binding Protein alpha Subunits, Gs/genetics ; Genes, p16 ; Humans ; Male ; Middle Aged ; Mutation, Missense/genetics ; Neoplasm Invasiveness ; Oncogene Proteins/genetics ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/mortality ; Predictive Value of Tests ; Prevalence ; Retrospective Studies ; Sensitivity and Specificity ; Severity of Illness Index ; Smad4 Protein/genetics ; Survival Analysis ; Ubiquitin-Protein Ligases ; United States

المؤلفون: Beleva Guthrie V; Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD., Masica DL; Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD., Fraser A; Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD., Federico J; Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD., Fan Y; Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD., Camps M; Department of Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA., Karchin R; Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD.; Department of Oncology, Johns Hopkins University Medicine, Baltimore, MD.

المصدر: Molecular biology and evolution [Mol Biol Evol] 2018 Jun 01; Vol. 35 (6), pp. 1507-1519.

نوع المنشور: Evaluation Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 8501455 Publication Model: Print Cited Medium: Internet ISSN: 1537-1719 (Electronic) Linking ISSN: 07374038 NLM ISO Abbreviation: Mol Biol Evol Subsets: MEDLINE

مواضيع طبية MeSH: Adaptation, Biological* , Evolution, Molecular* , Models, Genetic* , Mutation*, beta-Lactamases/*genetics, Phylogeny

المؤلفون: Zeng Q; Johns Hopkins School of Medicine, Baltimore, Maryland., Fu J; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland., Korrer M; Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee., Gorbounov M; Johns Hopkins School of Medicine, Baltimore, Maryland., Murray PJ; Johns Hopkins Hospital, Baltimore, Maryland; Max Planck Institute of Biochemistry, Munich, Germany., Pardoll D; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland., Masica DL; Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland., Kim YJ; Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee. y2.kim@vanderbilt.edu.; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.

المصدر: Cancer immunology research [Cancer Immunol Res] 2018 May; Vol. 6 (5), pp. 566-577. Date of Electronic Publication: 2018 Apr 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE

مواضيع طبية MeSH: Cell Proliferation*, Caspase 1/*physiology , Myeloid-Derived Suppressor Cells/*metabolism , Neoplasms/*pathology , T-Lymphocytes/*physiology, Adoptive Transfer ; Animals ; Caspase 1/metabolism ; Cells, Cultured ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Myeloid-Derived Suppressor Cells/pathology ; Myeloid-Derived Suppressor Cells/transplantation ; Neoplasms/immunology ; Neoplasms/metabolism ; Neoplasms/therapy

المؤلفون: Guidugli L; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Shimelis H; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Masica DL; Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD 21205, USA., Pankratz VS; Division of Nephrology, University of New Mexico, Albuquerque, NM 87131, USA., Lipton GB; Department of Statistical Science, Duke University, Durham, NC 27708, USA., Singh N; Department of Structural Biology, University of California, San Diego, San Diego, CA 92093, USA., Hu C; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Monteiro ANA; Cancer Epidemiology Program, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA., Lindor NM; Department of Health Sciences Research, Mayo Clinic, Scottsdale, AZ 85259, USA., Goldgar DE; Huntsman Cancer Institute and Department of Dermatology, University of Utah, Salt Lake City, UT 84132, USA., Karchin R; Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA., Iversen ES; Department of Statistical Science, Duke University, Durham, NC 27708, USA., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: couch.fergus@mayo.edu.

المصدر: American journal of human genetics [Am J Hum Genet] 2018 Feb 01; Vol. 102 (2), pp. 233-248. Date of Electronic Publication: 2018 Jan 25.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

مواضيع طبية MeSH: Algorithms* , Amino Acid Substitution* , Mutation, Missense*, BRCA2 Protein/*genetics , Breast Neoplasms/*genetics , Neoplasm Proteins/*genetics, Amino Acid Sequence ; Bayes Theorem ; Breast Neoplasms/diagnosis ; Breast Neoplasms/pathology ; Computational Biology/methods ; Databases, Genetic ; Female ; Gene Expression ; Genetic Testing ; Humans ; ROC Curve ; Sequence Alignment ; Sequence Homology, Amino Acid