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المؤلفون: O'Sullivan SS, Massey LA, Williams DR, Silveira-Moriyama L, Kempster PA, Holton JL, Revesz T, Lees AJ, O'Sullivan, S S, Massey, L A, Williams, D R, Silveira-Moriyama, L, Kempster, P A, Holton, J L, Revesz, T, Lees, A J

المصدر: Brain: A Journal of Neurology; May2008, Vol. 131 Issue 5, p1362-1372, 11p

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المؤلفون: Hou WC; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92122., Massey LA; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92122., Rhoades D; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92122., Wu Y; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92122., Ren W; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92122., Frank C; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92122., Overkleeft HS; Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden 2333 CC, The Netherlands., Kelly JW; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92122.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Aug 20; Vol. 121 (34), pp. e2320257121. Date of Electronic Publication: 2024 Aug 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Phosphatidylinositol 3-Kinases*/metabolism , Lysosomes*/metabolism , Lysosomes*/drug effects , Glucosylceramidase*/metabolism , Glucosylceramidase*/genetics , Fibroblasts*/metabolism , Fibroblasts*/drug effects , Lysosomal Storage Diseases*/drug therapy , Lysosomal Storage Diseases*/genetics , Lysosomal Storage Diseases*/metabolism, Humans ; Gaucher Disease/drug therapy ; Gaucher Disease/genetics ; Gaucher Disease/metabolism ; Phosphoinositide-3 Kinase Inhibitors/pharmacology

المؤلفون: Hardy MA; Department of Chemistry, University of California, Berkeley, CA 94720, USA., Hayward Cooke J; Department of Chemistry, University of California, Berkeley, CA 94720, USA., Feng Z; Department of Chemistry, University of California, Davis, CA 95616, USA., Noda K; Department of Chemistry, University of California, Berkeley, CA 94720, USA., Kerschgens I; Department of Chemistry, University of California, Berkeley, CA 94720, USA., Massey LA; Department of Chemistry, University of California, Berkeley, CA 94720, USA., Tantillo DJ; Department of Chemistry, University of California, Davis, CA 95616, USA., Sarpong R; Department of Chemistry, University of California, Berkeley, CA 94720, USA.

المصدر: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Jan 22; Vol. 63 (4), pp. e202317348. Date of Electronic Publication: 2023 Dec 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Elsasser S; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Elia LP; Center for Systems and Therapeutics and Taube/Koret Center for Neurodegenerative Disease Research, San Francisco, CA, USA.; The J. David Gladstone Institutes, San Francisco, CA, USA., Morimoto RI; Department of Molecular Biosciences, Rice Institute for Biomedical Research, Northwestern University, Evanston, IL, USA., Powers ET; Department of Chemistry, The Scripps Research Institute, La Jolla, CA USA., Finley D; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Costa B; Center for Systems and Therapeutics and Taube/Koret Center for Neurodegenerative Disease Research, San Francisco, CA, USA.; The J. David Gladstone Institutes, San Francisco, CA, USA., Budron M; Center for Systems and Therapeutics and Taube/Koret Center for Neurodegenerative Disease Research, San Francisco, CA, USA.; The J. David Gladstone Institutes, San Francisco, CA, USA., Tokuno Z; Center for Systems and Therapeutics and Taube/Koret Center for Neurodegenerative Disease Research, San Francisco, CA, USA.; The J. David Gladstone Institutes, San Francisco, CA, USA., Wang S; Center for Systems and Therapeutics and Taube/Koret Center for Neurodegenerative Disease Research, San Francisco, CA, USA.; The J. David Gladstone Institutes, San Francisco, CA, USA., Iyer RG; Center for Systems and Therapeutics and Taube/Koret Center for Neurodegenerative Disease Research, San Francisco, CA, USA.; The J. David Gladstone Institutes, San Francisco, CA, USA., Barth B; Center for Systems and Therapeutics and Taube/Koret Center for Neurodegenerative Disease Research, San Francisco, CA, USA.; The J. David Gladstone Institutes, San Francisco, CA, USA., Mockler E; Center for Systems and Therapeutics and Taube/Koret Center for Neurodegenerative Disease Research, San Francisco, CA, USA.; The J. David Gladstone Institutes, San Francisco, CA, USA., Finkbeiner S; Center for Systems and Therapeutics and Taube/Koret Center for Neurodegenerative Disease Research, San Francisco, CA, USA.; The J. David Gladstone Institutes, San Francisco, CA, USA.; Departments of Neurology and Physiology, UCSF, San Francisco, CA, USA., Gestwicki JE; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.; Institute for Neurodegenerative Disease, University of California San Francisco, San Francisco, CA, USA., Richardson RAK; Center for Genetic Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Institute on Complex Systems (NICO), Northwestern University, Evanston, IL, USA.; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL USA., Stoeger T; Center for Genetic Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Institute on Complex Systems (NICO), Northwestern University, Evanston, IL, USA.; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL USA., Tan EP; Department of Chemistry, The Scripps Research Institute, La Jolla, CA USA., Xiao Q; Department of Chemistry, The Scripps Research Institute, La Jolla, CA USA., Cole CM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA USA., Massey LA; Department of Chemistry, The Scripps Research Institute, La Jolla, CA USA., Garza D; Department of Chemistry, The Scripps Research Institute, La Jolla, CA USA., Kelly JW; Department of Chemistry, The Scripps Research Institute, La Jolla, CA USA.; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA., Rainbolt TK; Department of Biology and Genetics, Stanford University, Stanford, CA, USA., Chou CC; Department of Biology and Genetics, Stanford University, Stanford, CA, USA., Masto VB; Department of Biology and Genetics, Stanford University, Stanford, CA, USA., Frydman J; Department of Biology and Genetics, Stanford University, Stanford, CA, USA., Nixon RA; Center for Dementia Research, Nathan S. Kline Institute, Orangeburg, NY, USA.; Department of Psychiatry, New York University Langone Health, New York, NY, USA.; Department of Cell Biology, New York University Langone Health, New York, NY, USA.; NYU Neuroscience Institute, New York University Langone Health, New York, NY, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 24. Date of Electronic Publication: 2023 Mar 24.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Marichev KO; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Dong K; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Massey LA; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Deng Y; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., De Angelis L; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Wang K; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Arman H; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Doyle MP; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA. michael.doyle@utsa.edu.

المصدر: Nature communications [Nat Commun] 2019 Nov 22; Vol. 10 (1), pp. 5328. Date of Electronic Publication: 2019 Nov 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Azetines/*chemical synthesis , Cycloaddition Reaction/*methods, Amino Acids ; Azetidines ; Catalysis ; Chemistry Techniques, Synthetic/methods ; Diazonium Compounds ; Indicators and Reagents/chemical synthesis ; Stereoisomerism

المؤلفون: Marichev KO; Department of Chemistry, The University of Texas at San Antonio One UTSA Circle, San Antonio, TX, 78249, USA., Wang K; Department of Chemistry, The University of Texas at San Antonio One UTSA Circle, San Antonio, TX, 78249, USA., Dong K; Department of Chemistry, The University of Texas at San Antonio One UTSA Circle, San Antonio, TX, 78249, USA., Greco N; Department of Chemistry, The University of Texas at San Antonio One UTSA Circle, San Antonio, TX, 78249, USA., Massey LA; Department of Chemistry, The University of Texas at San Antonio One UTSA Circle, San Antonio, TX, 78249, USA., Deng Y; Department of Chemistry, The University of Texas at San Antonio One UTSA Circle, San Antonio, TX, 78249, USA., Arman H; Department of Chemistry, The University of Texas at San Antonio One UTSA Circle, San Antonio, TX, 78249, USA., Doyle MP; Department of Chemistry, The University of Texas at San Antonio One UTSA Circle, San Antonio, TX, 78249, USA.

المصدر: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2019 Nov 04; Vol. 58 (45), pp. 16188-16192. Date of Electronic Publication: 2019 Sep 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Jabbari E; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom.; Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, United Kingdom., Woodside J; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom.; Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, United Kingdom., Tan MMX; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom.; Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, United Kingdom., Pavese N; Division of Neuroscience, Newcastle University, Newcastle, United Kingdom., Bandmann O; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, United Kingdom., Ghosh BCP; Wessex Neurological Centre, University Hospitals Southampton NHS Foundation Trust, Southampton, United Kingdom., Massey LA; Department of Neurology, Poole Hospital NHS Foundation Trust, Poole, United Kingdom., Capps E; Care of the Elderly Department, Shrewsbury and Telford Hospital NHS Trust, Shrewsbury, United Kingdom., Warner TT; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London, United Kingdom.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, United Kingdom., Lees AJ; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London, United Kingdom.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, United Kingdom., Revesz T; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London, United Kingdom.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, United Kingdom., Holton JL; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London, United Kingdom.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, United Kingdom., Williams NM; Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, United Kingdom., Grosset DG; Department of Neurology, Institute of Neurological Sciences, Queen Elizabeth University Hospital, Glasgow, United Kingdom., Morris HR; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom.; Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, United Kingdom.

المصدر: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2019 Sep; Vol. 34 (9), pp. 1307-1314. Date of Electronic Publication: 2019 Jul 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8610688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8257 (Electronic) Linking ISSN: 08853185 NLM ISO Abbreviation: Mov Disord Subsets: MEDLINE

مواضيع طبية MeSH: Supranuclear Palsy, Progressive/*genetics , Supranuclear Palsy, Progressive/*pathology, Adult ; Age of Onset ; Aged ; Aged, 80 and over ; Diagnosis, Differential ; Disease Progression ; Female ; Gait Disorders, Neurologic/genetics ; Gait Disorders, Neurologic/pathology ; Genetic Testing ; Genotype ; Humans ; Male ; Middle Aged ; Parkinson Disease/genetics ; Parkinson Disease/pathology ; Predictive Value of Tests ; Tissue Banks ; Young Adult

المؤلفون: Cheng QQ; Department of Chemistry, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA., Massey LA; Department of Chemistry, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA., Willett BS; Department of Chemistry, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA., Deng Y; Department of Chemistry, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA.; Current address: Department of Chemistry, Western Kentucky University, Bowling Green, KY, 42101, USA., Arman H; Department of Chemistry, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA., Doyle MP; Department of Chemistry, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA.

المصدر: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2018 Aug 06; Vol. 57 (32), pp. 10343-10346. Date of Electronic Publication: 2018 Jul 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl

مواضيع طبية MeSH: Azo Compounds/*chemistry , Copper/*chemistry , Imides/*chemistry , Organometallic Compounds/*chemistry , Sulfur/*chemistry, Catalysis ; Cycloaddition Reaction ; Molecular Structure