المؤلفون: Gama, FHD, Dutra, LA, Hawgood, M, dos Reis, CV, Serafim, RAM, Ferreira, MA Jr, Teodoro, BVM, Takarada, J, Santiago, AS, Balourdas, DI, Nilsson, AS, Urien, B, Almeida, VM, Gileadi, C, Ramos, PZ, Salmazo, A, Vasconcelos, SNS, Cunha, MR, Mueller, S, Knapp, S, Massirer, KB, Elkins, JM, Gileadi, O, Mascarello, A, Lemmens, BBLG, Guimaraes, CRW, Azevedo, H, Counago, RM

المصدر: Journal of medicinal chemistry. 67(11):8609-8629

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:158249990

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المؤلفون: Cunha MR; State University of Campinas, Center of Molecular Biology and Genetic Engeneering, Dr. Andre Tosello avenue, 550, 13083-886, Campinas, BRAZIL., do Amaral BS; Instituto Federal de Educação Ciência e Tecnologia de São Paulo, Chemistry, BRAZIL., Takarada JE; State University of Campinas, Center of Medicinal Chemistry (CQMED), BRAZIL., Valderrama GV; State University of Campinas, Center of Medicinal Chemistry (CQMED), BRAZIL., Batista ANL; Universidade Federal Fluminense, Instituto de Química, BRAZIL., Batista JM Jr; Universidade Federal de Sao Paulo, Instituto de Ciência e Tecnologia, BRAZIL., Cass QB; Universidade Federal de São Carlos, Departamento de Química, BRAZIL., Couñago RM; University of North Carolina at Chapel Hill, Division of Chemical Biology and Medicinal Chemistry, UNITED STATES., Massirer KB; State University of Campinas, Center for Molecular Biology and Genetic Engeneering, Dr. Andre Tosello Av. 550, 13083-886, Campinas, BRAZIL.

المصدر: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Jun 25, pp. e202400506. Date of Electronic Publication: 2024 Jun 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE

المؤلفون: de Souza Gama FH; Aché Laboratórios Farmacêuticos S.A., Guarulhos, São Paulo 07034-904, Brazil., Dutra LA; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Hawgood M; Science for Life Laboratory, Sweden, Tomtebodavägen 23A, 17165 Solna, Sweden.; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Dos Reis CV; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Serafim RAM; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Ferreira MA Jr; Aché Laboratórios Farmacêuticos S.A., Guarulhos, São Paulo 07034-904, Brazil., Teodoro BVM; Aché Laboratórios Farmacêuticos S.A., Guarulhos, São Paulo 07034-904, Brazil., Takarada JE; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Santiago AS; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Balourdas DI; Institute of Pharmaceutical Chemistry, Johann Wolfgang Goethe University, Max-von-Laue-Str. 9, Frankfurt am Main 60438, Germany.; Structural Genomics Consortium (SGC), Buchmann Institute for Life Sciences, Johann Wolfgang Goethe University, Max-von-Laue-Str. 15, Frankfurt am Main 60438, Germany., Nilsson AS; Science for Life Laboratory, Sweden, Tomtebodavägen 23A, 17165 Solna, Sweden.; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Urien B; Science for Life Laboratory, Sweden, Tomtebodavägen 23A, 17165 Solna, Sweden.; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Almeida VM; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Gileadi C; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Ramos PZ; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Salmazo A; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Vasconcelos SNS; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Cunha MR; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Mueller S; Institute of Pharmaceutical Chemistry, Johann Wolfgang Goethe University, Max-von-Laue-Str. 9, Frankfurt am Main 60438, Germany.; Structural Genomics Consortium (SGC), Buchmann Institute for Life Sciences, Johann Wolfgang Goethe University, Max-von-Laue-Str. 15, Frankfurt am Main 60438, Germany., Knapp S; Institute of Pharmaceutical Chemistry, Johann Wolfgang Goethe University, Max-von-Laue-Str. 9, Frankfurt am Main 60438, Germany.; Structural Genomics Consortium (SGC), Buchmann Institute for Life Sciences, Johann Wolfgang Goethe University, Max-von-Laue-Str. 15, Frankfurt am Main 60438, Germany., Massirer KB; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Elkins JM; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Gileadi O; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil., Mascarello A; Aché Laboratórios Farmacêuticos S.A., Guarulhos, São Paulo 07034-904, Brazil., Lemmens BBLG; Science for Life Laboratory, Sweden, Tomtebodavägen 23A, 17165 Solna, Sweden.; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Guimarães CRW; Aché Laboratórios Farmacêuticos S.A., Guarulhos, São Paulo 07034-904, Brazil., Azevedo H; Aché Laboratórios Farmacêuticos S.A., Guarulhos, São Paulo 07034-904, Brazil., Couñago RM; Centro de Química Medicinal, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Av. Dr. André Tosello 550, 13083-886 Campinas, São Paulo Brazil.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Jun 13; Vol. 67 (11), pp. 8609-8629. Date of Electronic Publication: 2024 May 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/chemical synthesis , Protein Serine-Threonine Kinases*/antagonists & inhibitors , Protein Serine-Threonine Kinases*/metabolism , Pteridines*/pharmacology , Pteridines*/chemistry , Pteridines*/chemical synthesis, Humans ; Intracellular Signaling Peptides and Proteins/antagonists & inhibitors ; Intracellular Signaling Peptides and Proteins/metabolism ; Cell Proliferation/drug effects ; Structure-Activity Relationship ; Casein Kinase Idelta/antagonists & inhibitors ; Casein Kinase Idelta/metabolism ; Casein Kinase 1 epsilon/antagonists & inhibitors ; Casein Kinase 1 epsilon/metabolism ; Cell Line, Tumor

المؤلفون: Vergani-Junior CA; Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.; Program in Genetics and Molecular Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil., Moro RP; Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.; Program in Genetics and Molecular Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil., Pinto S; Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.; Program in Genetics and Molecular Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil., De-Souza EA; Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil., Camara H; Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.; Program in Genetics and Molecular Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.; Section on Integrative Physiology & Metabolism, Joslin Diabetes Center, Boston, MA, USA., Braga DL; Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.; Program in Genetics and Molecular Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil., Tonon-da-Silva G; Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.; Program in Genetics and Molecular Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil., Knittel TL; Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.; Program in Genetics and Molecular Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil., Ruiz GP; Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.; Program in Genetics and Molecular Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil., Ludwig RG; Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.; Program in Genetics and Molecular Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil., Massirer KB; Center for Molecular Biology and Genetic Engineering (CBMEG), Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.; Center of Medicinal Chemistry (CQMED), Universidade Estadual de Campinas, Campinas, São Paulo, Brazil., Mair WB; Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA, USA., Mori MA; Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil. morima@unicamp.br.; Program in Genetics and Molecular Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil. morima@unicamp.br.; Obesity and Comorbidities Research Center (OCRC), Universidade Estadual de Campinas, Campinas, São Paulo, Brazil. morima@unicamp.br.; Experimental Medicine Research Cluster (EMRC), Universidade Estadual de Campinas, Campinas, São Paulo, Brazil. morima@unicamp.br.

المصدر: Nature communications [Nat Commun] 2024 Apr 09; Vol. 15 (1), pp. 3070. Date of Electronic Publication: 2024 Apr 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Caenorhabditis elegans Proteins*/metabolism , MicroRNAs*/genetics , MicroRNAs*/metabolism, Animals ; Humans ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Oxidative Stress/genetics ; Glucagon-Like Peptide 1/metabolism ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism