المؤلفون: Matchett, KP, Wilson-Kanamori, JR, Portman, JR, Kapourani, CA, Fercoq, F, May, S, Zajdel, E, Beltran, M, Sutherland, EF, Mackey, JBG, Brice, M, Wilson, GC, Wallace, SJ, Kitto, L, Younger, NT, Dobie, R, Mole, DJ, Oniscu, GC, Wigmore, SJ, Ramachandran, P, Vallejos, CA, Carragher, NO, Saeidinejad, MM, Quaglia, A, Jalan, R, Simpson, KJ, Kendall, TJ, Rule, JA, Lee, WM, Hoare, M, Weston, CJ, Marioni, JC, Teichmann, SA, Bird, TG, Carlin, LM, Henderson, NC

المصدر: Nature. 629(630):158-165

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:158226172

المؤلفون: Dobie, R, Wilson-Kanamori, JR, Henderson, BEP, Smith, JR, Matchett, KP, Portman, JR, Wallenborg, K, Picelli, S, Zagorska, A, Pendem, SV, Hudson, TE, Wu, MM, Budas, GR, Breckenridge, DG, Harrison, EM, Mole, DJ, Wigmore, SJ, Ramachandran, P, Ponting, CP, Teichmann, SA, Marioni, JC, Henderson, NC

المصدر: Cell reports. 29(7):1832

مصطلحات موضوعية: Medicin och hälsovetenskap, Klinisk medicin, Gastroenterologi, Medicinska och farmaceutiska grundvetenskaper, Cell- och molekylärbiologi

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:142320271

المؤلفون: Ramachandran, P, Dobie, R, Wilson-Kanamori, Dora, EF, Henderson, BEP, Luu, NT, Portman, Matchett, KP, Brice, M, Marwick, JA, Taylor, RS, Efremova, M, Vento-Tormo, R, Carragher, NO, Kendall, TJ, Fallowfield, JA, Harrison, EM, Mole, DJ, Wigmore, SJ, Newsome, PN, Weston, CJ, Iredale, JP, Tacke, F, Pollard, JW, Ponting, CP, Marioni, JC, Teichmann, SA, Henderson, NC

مصطلحات موضوعية: Liver Cirrhosis, Male, Membrane Glycoproteins, Receptor, Platelet-Derived Growth Factor alpha, Macrophages, Transendothelial and Transepithelial Migration, Endothelial Cells, Membrane Proteins, Receptors, Cell Surface, Tetraspanin 29, 3. Good health, Mice, Phenotype, Liver, Case-Control Studies, Hepatic Stellate Cells, Hepatocytes, Animals, Humans, Cell Lineage, Female, Receptors, Immunologic, Single-Cell Analysis, Duffy Blood-Group System, Transcriptome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::58bdba740e74720f66c9a3a24263014e

المؤلفون: Matchett KP; Centre for Inflammation Research, Institute for Regeneration and Repair, Edinburgh BioQuarter, University of Edinburgh, Edinburgh, UK., Paris J; Centre for Inflammation Research, Institute for Regeneration and Repair, Edinburgh BioQuarter, University of Edinburgh, Edinburgh, UK., Teichmann SA; Wellcome Sanger Institute, Cambridge, UK.; Department of Physics, Cavendish Laboratory, University of Cambridge, Cambridge, UK., Henderson NC; Centre for Inflammation Research, Institute for Regeneration and Repair, Edinburgh BioQuarter, University of Edinburgh, Edinburgh, UK. Neil.Henderson@ed.ac.uk.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK. Neil.Henderson@ed.ac.uk.

المصدر: Nature reviews. Gastroenterology & hepatology [Nat Rev Gastroenterol Hepatol] 2024 Apr 23. Date of Electronic Publication: 2024 Apr 23.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500079 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-5053 (Electronic) Linking ISSN: 17595045 NLM ISO Abbreviation: Nat Rev Gastroenterol Hepatol Subsets: MEDLINE

المؤلفون: Lechertier T; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK., Reynolds LE; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK., Kim H; Cell Death & Inflammation, The Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK., Pedrosa AR; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK., Gómez-Escudero J; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK., Muñoz-Félix JM; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK., Batista S; Systems Oncology Group, Champalimaud Research, Champalimaud Centre for the Unknown Av. Brasília, Doca de Pedrouços, 1400-038, Lisbon, Portugal., Dukinfield M; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK., Demircioglu F; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK., Wong PP; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 510120, Guangzhou, China., Matchett KP; Centre for Inflammation Research, The Queen's Medical Research Institute, Edinburgh BioQuarter, University of Edinburgh, Edinburgh, UK., Henderson NC; Centre for Inflammation Research, The Queen's Medical Research Institute, Edinburgh BioQuarter, University of Edinburgh, Edinburgh, UK.; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh, UK., D'Amico G; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK., Parsons M; Nikon Imaging Centre@King's, Randall Division of Cell and Molecular Biophysics, Kings College London, Room 3.22B, New Hunts House Guys Campus, London, SE1 1UL, UK., Harwood C; Centre for Cell Biology and Cutaneous Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, UK., Meier P; Cell Death & Inflammation, The Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK., Hodivala-Dilke KM; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK. k.hodivala-dilke@qmul.ac.uk.

المصدر: Nature communications [Nat Commun] 2023 Sep 06; Vol. 14 (1), pp. 5446. Date of Electronic Publication: 2023 Sep 06.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: O'Sullivan ED; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK.; Kidney Health Service, Royal Brisbane and Women's Hospital, Brisbane, Queensland 4029, Australia., Mylonas KJ; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Xin C; Renal Division and Division of Engineering in Medicine, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Baird DP; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Carvalho C; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Docherty MH; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Campbell R; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Matchett KP; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Waddell SH; Cancer Research UK Scotland Centre and MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh EH4 2XU, UK., Walker AD; Cancer Research UK Scotland Centre and MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh EH4 2XU, UK., Gallagher KM; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK.; Department of Urology, Western General Hospital, Edinburgh EH4 2XU, UK., Jia S; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Leung S; Department of Urology, Western General Hospital, Edinburgh EH4 2XU, UK., Laird A; Department of Urology, Western General Hospital, Edinburgh EH4 2XU, UK., Wilflingseder J; Renal Division and Division of Engineering in Medicine, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.; Department of Physiology and Pathophysiology, University of Veterinary Medicine, Veterinärplatz 1, 1210 Vienna, Austria., Willi M; Laboratory of Genetics and Physiology, NIDDK, NIH, Bethesda, MD 20892, USA., Reck M; Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Finnie S; Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Pisco A; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA., Gordon-Keylock S; Centre for Regenerative Medicine. University of Edinburgh, Edinburgh EH16 4UU, UK., Medvinsky A; Centre for Regenerative Medicine. University of Edinburgh, Edinburgh EH16 4UU, UK., Boulter L; Cancer Research UK Scotland Centre and MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh EH4 2XU, UK., Henderson NC; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK.; Cancer Research UK Scotland Centre and MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh EH4 2XU, UK., Kirschner K; School of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK., Chandra T; Cancer Research UK Scotland Centre and MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh EH4 2XU, UK., Conway BR; Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Hughes J; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Denby L; Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Bonventre JV; Renal Division and Division of Engineering in Medicine, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Ferenbach DA; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK.; Renal Division and Division of Engineering in Medicine, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

المصدر: Science translational medicine [Sci Transl Med] 2023 May 31; Vol. 15 (698), pp. eabn0736. Date of Electronic Publication: 2023 May 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Hedgehog Proteins*/metabolism , Renal Insufficiency, Chronic*, Animals ; Humans ; Mice ; Fibrosis ; Inflammation ; NF-kappa B ; Tumor Necrosis Factors ; Zinc Finger Protein GLI1

المؤلفون: Wang S; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Li K; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Pickholz E; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Dobie R; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Matchett KP; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Henderson NC; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh EH16 4TJ, UK., Carrico C; Gordian Biotechnology, San Francisco, CA 94107, USA., Driver I; Gordian Biotechnology, San Francisco, CA 94107, USA., Borch Jensen M; Gordian Biotechnology, San Francisco, CA 94107, USA., Chen L; PharmaNest Inc., Princeton, NJ 08540, USA., Petitjean M; PharmaNest Inc., Princeton, NJ 08540, USA., Bhattacharya D; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Fiel MI; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Liu X; Department of Surgery, University of California, San Diego, La Jolla, CA 92093, USA., Kisseleva T; Department of Surgery, University of California, San Diego, La Jolla, CA 92093, USA., Alon U; Department Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel., Adler M; Tananbaum Center for Theoretical and Analytical Human Biology, Yale University School of Medicine, New Haven, CT 06510, USA., Medzhitov R; Howard Hughes Medical Institute, Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA., Friedman SL; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

المصدر: Science translational medicine [Sci Transl Med] 2023 Jan 04; Vol. 15 (677), pp. eadd3949. Date of Electronic Publication: 2023 Jan 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Non-alcoholic Fatty Liver Disease*/pathology, Humans ; Mice ; Animals ; Hepatic Stellate Cells/pathology ; Autocrine Communication ; Fibrosis ; Liver Cirrhosis/pathology ; Liver

المؤلفون: Richter ML; Helmholtz Pioneer Campus (HPC), Helmholtz Zentrum München, Neuherberg, Germany., Deligiannis IK; Helmholtz Pioneer Campus (HPC), Helmholtz Zentrum München, Neuherberg, Germany., Yin K; Helmholtz Pioneer Campus (HPC), Helmholtz Zentrum München, Neuherberg, Germany.; University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge, United Kingdom., Danese A; Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany., Lleshi E; University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge, United Kingdom., Coupland P; University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge, United Kingdom., Vallejos CA; MRC Human Genetics Unit, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom., Matchett KP; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Little France Crescent, Edinburgh, United Kingdom., Henderson NC; MRC Human Genetics Unit, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Little France Crescent, Edinburgh, United Kingdom., Colome-Tatche M; Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany. maria.colome@helmholtz-muenchen.de.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany. maria.colome@helmholtz-muenchen.de.; Biomedical Center (BMC), Physiological Chemistry, Faculty of Medicine, LMU Munich, Munich, Germany. maria.colome@helmholtz-muenchen.de., Martinez-Jimenez CP; Helmholtz Pioneer Campus (HPC), Helmholtz Zentrum München, Neuherberg, Germany. celia.martinez@helmholtz-muenchen.de.; TUM School of Medicine, Technical University of Munich, Munich, Germany. celia.martinez@helmholtz-muenchen.de.

المصدر: Nature communications [Nat Commun] 2021 Jul 12; Vol. 12 (1), pp. 4264. Date of Electronic Publication: 2021 Jul 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Ploidies* , Sequence Analysis, RNA* , Single-Cell Analysis*, Liver/*metabolism, Animals ; Biomarkers/metabolism ; Cell Nucleus/metabolism ; Chronic Disease ; Frozen Sections ; Gene Expression Profiling ; Gene Expression Regulation ; Gene Ontology ; Hepatocytes/metabolism ; Liver/pathology ; Liver Diseases/pathology ; Mice, Inbred C57BL ; Regeneration ; Stem Cells/metabolism ; Transcription Factors/metabolism ; Transcription, Genetic ; Mice

المؤلفون: Matthews O; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, United Kingdom., Morrison EE; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, United Kingdom., Tranter JD; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, United Kingdom., Starkey Lewis P; Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, United Kingdom., Toor IS; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, United Kingdom., Srivastava A; AstraZeneca, Clinical Pharmacology & Safety Sciences Department, Biopharmaceuticals Science Unit, Darwin Building 310, Cambridge Science Park, Milton Rd, Cambridge, CB4 0FZ. United Kingdom., Sargeant R; AstraZeneca, Clinical Pharmacology & Safety Sciences Department, Biopharmaceuticals Science Unit, Darwin Building 310, Cambridge Science Park, Milton Rd, Cambridge, CB4 0FZ. United Kingdom., Rollison H; AstraZeneca, Clinical Pharmacology & Safety Sciences Department, Biopharmaceuticals Science Unit, Darwin Building 310, Cambridge Science Park, Milton Rd, Cambridge, CB4 0FZ. United Kingdom., Matchett KP; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, United Kingdom., Kendall TJ; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, United Kingdom., Gray GA; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, United Kingdom., Goldring C; Department of Molecular and Clinical Pharmacology, MRC Centre for Drug Safety Science, University of Liverpool, United Kingdom., Park K; Department of Molecular and Clinical Pharmacology, MRC Centre for Drug Safety Science, University of Liverpool, United Kingdom., Denby L; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, United Kingdom., Dhaun N; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, United Kingdom., Bailey MA; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, United Kingdom., Henderson NC; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, United Kingdom; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, United Kingdom., Williams D; AstraZeneca, Clinical Pharmacology & Safety Sciences Department, Biopharmaceuticals Science Unit, Darwin Building 310, Cambridge Science Park, Milton Rd, Cambridge, CB4 0FZ. United Kingdom., Dear JW; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, United Kingdom. Electronic address: james.dear@ed.ac.uk.

المصدر: EBioMedicine [EBioMedicine] 2020 Dec; Vol. 62, pp. 103092. Date of Electronic Publication: 2020 Nov 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation* , RNA Interference*, Cytochrome P-450 CYP2E1/*genetics , Epithelial Cells/*metabolism , Hepatocytes/*metabolism , Kidney Tubules/*metabolism , MicroRNAs/*genetics, Animals ; Cytochrome P-450 CYP2E1/metabolism ; Female ; Kidney Tubules/cytology ; Male ; Mice ; Mice, Knockout ; Mice, Transgenic ; MicroRNAs/administration & dosage ; Organ Specificity/genetics

المؤلفون: Ramachandran P; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Matchett KP; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Dobie R; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Wilson-Kanamori JR; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Henderson NC; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK. Neil.Henderson@ed.ac.uk.; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK. Neil.Henderson@ed.ac.uk.

المصدر: Nature reviews. Gastroenterology & hepatology [Nat Rev Gastroenterol Hepatol] 2020 Aug; Vol. 17 (8), pp. 457-472. Date of Electronic Publication: 2020 Jun 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500079 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-5053 (Electronic) Linking ISSN: 17595045 NLM ISO Abbreviation: Nat Rev Gastroenterol Hepatol Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Profiling* , Single-Cell Analysis*, Liver/*metabolism , Liver Diseases/*genetics, Endothelial Cells/metabolism ; Endothelial Cells/physiology ; Fibroblasts/metabolism ; Fibroblasts/physiology ; Gastroenterology ; Hepatic Stellate Cells/metabolism ; Hepatic Stellate Cells/physiology ; Hepatocytes/metabolism ; Hepatocytes/physiology ; Humans ; Inflammation/immunology ; Kupffer Cells/immunology ; Liver/cytology ; Liver/immunology ; Liver/physiology ; Liver Cirrhosis/genetics ; Liver Cirrhosis/immunology ; Liver Cirrhosis/metabolism ; Liver Diseases/immunology ; Liver Diseases/metabolism ; Macrophages/immunology ; Muscle, Smooth, Vascular/cytology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/physiology ; Regeneration ; Sequence Analysis, RNA