المؤلفون: Patel SB; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama, Birmingham, AL; Division of Hematology, University of Colorado Anschutz Medical Campus, Aurora, CO., Kuznetsova V; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama, Birmingham, AL., Matkins VR; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama, Birmingham, AL., Franceski AM; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama, Birmingham, AL., Bassal MA; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA; Cancer Institute of Singapore, National University of Singapore, Singapore, Singapore., Welner RS; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama, Birmingham, AL. Electronic address: rwelner@uab.edu.

المصدر: Experimental hematology [Exp Hematol] 2022 Nov; Vol. 115, pp. 1-13. Date of Electronic Publication: 2022 Sep 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Inc Country of Publication: Netherlands NLM ID: 0402313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2399 (Electronic) Linking ISSN: 0301472X NLM ISO Abbreviation: Exp Hematol Subsets: MEDLINE

مواضيع طبية MeSH: Transcriptome* , Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy, Mice ; Animals ; Neoplastic Stem Cells/metabolism ; Transforming Growth Factor beta/metabolism

المؤلفون: Patel SB; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA., Nemkov T; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Stefanoni D; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Benavides GA; Department of Pathology, Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, USA., Bassal MA; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Cancer Institute of Singapore, National University of Singapore, Singapore, Singapore., Crown BL; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA., Matkins VR; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA., Camacho V; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA., Kuznetsova V; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA., Hoang AT; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA., Tenen DE; Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Wolock SL; Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Park J; Dicerna Pharmaceuticals, Inc., Lexington, MA, USA., Ying L; Cancer Institute of Singapore, National University of Singapore, Singapore, Singapore., Yue Z; Informatics Institute, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Chen JY; Informatics Institute, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Yang H; Cancer Institute of Singapore, National University of Singapore, Singapore, Singapore., Tenen DG; Cancer Institute of Singapore, National University of Singapore, Singapore, Singapore., Ferrell PB; Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA., Lu R; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA., Darley-Usmar V; Department of Pathology, Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, USA., D'Alessandro A; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Bhatia R; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA., Welner RS; Department of Medicine, Division of Hematology/Oncology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA. rwelner@uab.edu.

المصدر: Leukemia [Leukemia] 2021 Dec; Vol. 35 (12), pp. 3371-3382. Date of Electronic Publication: 2021 Jun 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm* , Metabolome* , Transcriptome*, Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy , Neoplastic Stem Cells/*drug effects , STAT3 Transcription Factor/*metabolism , Small Molecule Libraries/*pharmacology, Animals ; Apoptosis ; Female ; Glycolysis ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/metabolism ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; Male ; Mice ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Protein Kinase Inhibitors/pharmacology ; STAT3 Transcription Factor/genetics

المؤلفون: Camacho V; Division of Hematology-Oncology., Matkins VR; Division of Hematology-Oncology., Patel SB; Division of Hematology-Oncology., Lever JM; Nephrology Research and Training Center, Division of Nephrology, Department of Medicine, and., Yang Z; Division of Cardiothoracic Surgery, Department of Surgery, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Ying L; Cancer Science Institute of Singapore & Department of Biochemistry, National University of Singapore, Singapore., Landuyt AE; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Dean EC; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA., George JF; Division of Cardiothoracic Surgery, Department of Surgery, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Yang H; Cancer Science Institute of Singapore & Department of Biochemistry, National University of Singapore, Singapore., Ferrell PB; Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Maynard CL; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Weaver CT; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Turnquist HR; Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Welner RS; Division of Hematology-Oncology.

المصدر: JCI insight [JCI Insight] 2020 Nov 19; Vol. 5 (22). Date of Electronic Publication: 2020 Nov 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Hematopoiesis*, Bone Marrow Cells/*physiology , Hematopoietic Stem Cells/*physiology , Interleukin-10/*metabolism , Mesenchymal Stem Cells/*physiology , Stromal Cells/*physiology , T-Lymphocytes, Regulatory/*immunology, Animals ; Bone Marrow Cells/cytology ; Bone Marrow Cells/immunology ; Cell Communication ; Cell Proliferation ; Cells, Cultured ; Coculture Techniques ; Female ; Hematopoietic Stem Cells/cytology ; Hematopoietic Stem Cells/immunology ; Male ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/immunology ; Mice ; Mice, Inbred C57BL ; Stromal Cells/cytology ; Stromal Cells/immunology