نتائج البحث - "Matthew L Pearn"

1

دورية أكاديمية

An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.

المصدر: PLoS ONE, Vol 11, Iss 3, p e0152471 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4811554?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/e6e5615e619c41a0ad64eafb049c71c7

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2

دورية أكاديمية

A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP.

المؤلفون: April M Weissmiller, Orlangie Natera-Naranjo, Sol M Reyna, Matthew L Pearn, Xiaobei Zhao, Phuong Nguyen, Soan Cheng, Lawrence S B Goldstein, Rudolph E Tanzi, Steven L Wagner, William C Mobley, Chengbiao Wu

المصدر: PLoS ONE, Vol 10, Iss 2, p e0118379 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/67d94cb4c74847f09dd63eb7f1a20f27

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3

دورية أكاديمية

Loss of caveolin-1 accelerates neurodegeneration and aging.

المؤلفون: Brian P Head, Jason N Peart, Mathivadhani Panneerselvam, Takaakira Yokoyama, Matthew L Pearn, Ingrid R Niesman, Jacqueline A Bonds, Jan M Schilling, Atsushi Miyanohara, John Headrick, Sameh S Ali, David M Roth, Piyush M Patel, Hemal H Patel

المصدر: PLoS ONE, Vol 5, Iss 12, p e15697 (2010)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3009734?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/e9ff5077de67451e9e57a9790d69abee

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4

دورية أكاديمية

Real-time Imaging of Axonal Transport of Quantum Dot-labeled BDNF in Primary Neurons

المؤلفون: Xiaobei Zhao, author¹, Yue Zhou, author², April M. Weissmiller, author¹, Matthew L. Pearn, author^{3, 4}, William C. Mobley, author¹, Chengbiao Wu, author¹

المصدر: Journal of Visualized Experiments. (91)

الإتاحة: http://www.jove.com/video/51899

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5

Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model

المؤلفون: Xu-Qiao Chen, Phuong Nguyen, William C. Mobley, Maria Maccecchini, Alexander M. Kleschevnikov, Matthew L. Pearn, Ahmad Salehi, Cassia R. Overk

المصدر: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 17, iss 2
Alzheimer's & Dementia

مصطلحات موضوعية: 0301 basic medicine, early endosome, Aging, Posiphen, Epidemiology, Physostigmine, Down syndrome, Tropomyosin receptor kinase B, Neurodegenerative, Alzheimer's Disease, Mice, Amyloid beta-Protein Precursor, 0302 clinical medicine, Amyloid precursor protein, Ts65Dn mouse, 2.1 Biological and endogenous factors, Phosphorylation, Aetiology, Neurons, education.field_of_study, biology, Kinase, Health Policy, Theoretical Article, Alzheimer's disease, Cell biology, neurotrophin signaling, Psychiatry and Mental health, Phenotype, Neurological, Signal transduction, Amyloid beta, Intellectual and Developmental Disabilities (IDD), Population, Clinical Sciences, Endosomes, CREB, 03 medical and health sciences, Cellular and Molecular Neuroscience, Developmental Neuroscience, Alzheimer Disease, mental disorders, Acquired Cognitive Impairment, Genetics, Animals, Humans, education, Protein kinase B, Amyloid beta-Peptides, Animal, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Brain Disorders, Disease Models, Animal, 030104 developmental biology, Geriatrics, Disease Models, biology.protein, Dementia, Neurology (clinical), Cholinesterase Inhibitors, Geriatrics and Gerontology, APP, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691143f65dfced6635b43343f8af2cf7
https://escholarship.org/uc/item/4d04n1ns

6

Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTRin Nociception

المؤلفون: Kijung Sung, Wanlin Yang, William C. Mobley, Michael T. Maloney, Luiz F. Ferrari, Matthew L. Pearn, ChiHye Chung, Chengbiao Wu, Yingli Gu, Jon D. Levine, Bianxiao Cui, Kai Zhang, Xiaobei Zhao, Suzhen Lin

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 38, iss 14

مصطلحات موضوعية: Male, Nociception, 0301 basic medicine, sensory neuron, Tropomyosin receptor kinase A, Medical and Health Sciences, PC12 Cells, Rats, Sprague-Dawley, Mice, 0302 clinical medicine, Neurotrophic factors, Receptors, Nerve Growth Factor, Hereditary sensory and autonomic neuropathy, Hereditary Sensory and Autonomic Neuropathies, Receptor, Research Articles, Cells, Cultured, NGF, Cultured, TrkA, trophic, Chemistry, Growth Factor, General Neuroscience, Pain Research, 3T3 Cells, Cell biology, medicine.anatomical_structure, Neurological, Hyperalgesia, Chronic Pain, medicine.symptom, Signal transduction, Protein Binding, Signal Transduction, p75, Cells, Mutation, Missense, Nerve Tissue Proteins, Receptors, Nerve Growth Factor, Biology, 03 medical and health sciences, medicine, Animals, Humans, Receptors, Growth Factor, Receptor, trkA, Peripheral Neuropathy, Neurology & Neurosurgery, Psychology and Cognitive Sciences, Wild type, Neurosciences, medicine.disease, Sensory neuron, Rats, HEK293 Cells, 030104 developmental biology, Nerve growth factor, nervous system, Mutation, Sprague-Dawley, Missense, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cccb38002beb168e3299036c766c3a3
https://doi.org/10.1523/jneurosci.1686-17.2018

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Standards for preclinical research and publications in developmental anaesthetic neurotoxicity: expert opinion statement from the SmartTots preclinical working group

المؤلفون: Jeffrey W. Sall, Jerri Chen, Jennifer J. Lee, Gregory A. Chinn, Laszlo Vutskits, Vesna Jevtovic-Todorovic, Ansgar M. Brambrink, Cyrus D. Mintz, Andreas W. Loepke, Matthew L. Pearn, Zeljko J. Bosnjak, Lena S. Sun

المصدر: Br J Anaesth
British journal of anaesthesia, vol 124, iss 5

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b43478c1a0d61deeade354ead9eeca
https://pubmed.ncbi.nlm.nih.gov/32145876

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RhoA inhibition and Rac1 Activation Increases Mitochondrial Respiration in Propofol Induced Neonatal Neurotoxicity

المؤلفون: Matthew L. Pearn, Brian P. Head, Mehul Dhanani, Piyush M. Patel, Shanshan Wang, Joseph Leem, Hemal H. Patel

المصدر: The FASEB Journal. 33

مصطلحات موضوعية: RHOA, biology, Chemistry, Neurotoxicity, RAC1, Pharmacology, medicine.disease, Biochemistry, Mitochondrial respiration, Genetics, medicine, biology.protein, Propofol, Molecular Biology, Biotechnology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::999f09ff3caedb4e10e82880606b6141
https://doi.org/10.1096/fasebj.2019.33.1_supplement.813.16

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9

Membrane lipid rafts and neurobiology: age-related changes in membrane lipids and loss of neuronal function

المؤلفون: Piyush M. Patel, Brian P. Lemkuil, Matthew L. Pearn, Junji Egawa, Brian P. Head

المصدر: The Journal of Physiology. 594:4565-4579

مصطلحات موضوعية: 0301 basic medicine, Scaffold protein, Physiology, Membrane lipids, Cholesterol binding, Biology, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Neurotransmitter receptor, Caveolin, Signal transduction, Cytoskeleton, Lipid raft, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::991b01c6ed41936fad447899baaa2140
https://doi.org/10.1113/jp270590

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10

Inhibition of RhoA reduces propofol-mediated growth cone collapse, axonal transport impairment, loss of synaptic connectivity, and behavioural deficits

المؤلفون: Sushil K. Mahata, M. Kodama, McKenzie J. Fannon-Pavlich, M. Jian, J. Bertoglio, Jan M. Schilling, U. Nguyen, William C. Mobley, Junji Egawa, Brian P. Head, Chengbiao Wu, Ru-Quan Han, Piyush M. Patel, Matthew L. Pearn, Brian P. Lemkuil, Chitra D. Mandyam, Céline DerMardirossian, Hemal H. Patel

المصدر: British journal of anaesthesia. 120(4)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a65ca13dc131f5962d5e9a96ff2a2af
https://pubmed.ncbi.nlm.nih.gov/29576115

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