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1دورية أكاديمية
المؤلفون: Maupin KA; Van Andel Institute, Grand Rapids, MI, USA., Diegel CR; Van Andel Institute, Grand Rapids, MI, USA., Stevens PD; Van Andel Institute, Grand Rapids, MI, USA., Dick D; Van Andel Institute, Grand Rapids, MI, USA., Williams BO; Van Andel Institute, Grand Rapids, MI, USA.
مؤلفون مشاركون: VAI Vivarium and Transgenic Core; Van Andel Institute, Grand Rapids, MI, USA.
المصدر: FEBS open bio [FEBS Open Bio] 2022 Oct; Vol. 12 (10), pp. 1717-1728. Date of Electronic Publication: 2022 Sep 14.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 101580716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-5463 (Electronic) Linking ISSN: 22115463 NLM ISO Abbreviation: FEBS Open Bio Subsets: MEDLINE
مواضيع طبية MeSH: Cancellous Bone*/growth & development , Cortical Bone*/growth & development , Galectin 3*/genetics, Androgens ; Animals ; Arginine ; Female ; Fibroblasts/metabolism ; Humans ; Male ; Mice ; Mice, Knockout ; Mutation ; Polysaccharides ; Serine/genetics
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2دورية أكاديمية
المؤلفون: Zamarioli A; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, United States.; Department of Orthopaedics and Anaesthesiology, Ribeirão Preto Medical School, São Paulo, Brazil., Adam G; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, United States., Maupin KA; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, United States., Childress PJ; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, United States., Brinker A; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, United States., Ximenez JPB; Laboratory of Molecular Biology, Blood Center of Ribeirão Preto, Medical School, São Paulo, Brazil., Chakraborty N; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD, United States., Gautam A; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD, United States., Hammamieh R; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD, United States., Kacena MA; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, United States.; Richard L. Roudebush VA Medical Center, Indianapolis, IN, United States.
المصدر: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2022 Aug 15; Vol. 13, pp. 910901. Date of Electronic Publication: 2022 Aug 15 (Print Publication: 2022).
نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
مواضيع طبية MeSH: Femoral Fractures*/diagnostic imaging , Femoral Fractures*/etiology , Space Flight*, Animals ; Bone Morphogenetic Protein 2 ; Bone and Bones ; Male ; Mice ; X-Ray Microtomography
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3دورية أكاديمية
المؤلفون: Bhatti FUR; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA; Richard L. Roudebush VA Medical Center, IN, USA., Dadwal UC; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA; Richard L. Roudebush VA Medical Center, IN, USA., Valuch CR; Department of Biology, Indiana University Purdue University Indianapolis, IN, USA., Tewari NP; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA., Awosanya OD; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA., de Andrade Staut C; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA., Sun S; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA., Mendenhall SK; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA., Perugini AJ 3rd; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA., Nagaraj RU; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA., Battina HL; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA., Nazzal MK; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA., Blosser RJ; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA; Richard L. Roudebush VA Medical Center, IN, USA., Maupin KA; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA., Childress PJ; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA; Richard L. Roudebush VA Medical Center, IN, USA., Li J; Department of Biology, Indiana University Purdue University Indianapolis, IN, USA., Kacena MA; Department of Orthopaedic Surgery, Indiana University School of Medicine, IN, USA; Richard L. Roudebush VA Medical Center, IN, USA. Electronic address: mkacena@iupui.edu.
المصدر: Bone [Bone] 2021 May; Vol. 146, pp. 115883. Date of Electronic Publication: 2021 Feb 11.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8504048 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2763 (Electronic) Linking ISSN: 18732763 NLM ISO Abbreviation: Bone Subsets: MEDLINE
مواضيع طبية MeSH: Diabetes Mellitus, Experimental* , Femoral Fractures*, Animals ; Cell Proliferation ; Diet, High-Fat/adverse effects ; Endothelial Cells ; Mice
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4دورية أكاديمية
المؤلفون: Zamarioli A; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Orthopaedics and Anaesthesiology, Ribeirão Preto Medical School, Ribeirão Preto, SP, Brazil., Campbell ZR; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.; Marian University College of Osteopathic Medicine, Indianapolis, IN, USA., Maupin KA; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA., Childress PJ; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA., Ximenez JPB; Laboratory of Molecular Biology, Blood Center of Ribeirão Preto, Medical School, Ribeirão Pre, SP, Brazil., Adam G; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA., Chakraborty N; Medical Readiness Systems Biology, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Geneva Foundation, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Gautam A; Medical Readiness Systems Biology, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Hammamieh R; Medical Readiness Systems Biology, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Kacena MA; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA. mkacena@iupui.edu.; Richard L. Roudebush VA Medical Center, Indianapolis, IN, USA. mkacena@iupui.edu.
المصدر: NPJ microgravity [NPJ Microgravity] 2021 Mar 26; Vol. 7 (1), pp. 12. Date of Electronic Publication: 2021 Mar 26.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Springer Nature Country of Publication: United States NLM ID: 101703605 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8065 (Print) Linking ISSN: 23738065 NLM ISO Abbreviation: NPJ Microgravity Subsets: PubMed not MEDLINE
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5دورية أكاديمية
المؤلفون: Kanagasabapathy D; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Blosser RJ; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Maupin KA; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Hong JM; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN 46202, USA., Alvarez M; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Ghosh J; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Mohamad SF; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Aguilar-Perez A; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN 46202, USA., Srour EF; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Kacena MA; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Bruzzaniti A; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN 46202, USA.
المصدر: Aging [Aging (Albany NY)] 2020 Jul 07; Vol. 12 (14), pp. 15121-15133. Date of Electronic Publication: 2020 Jul 07.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural
بيانات الدورية: Publisher: Impact Journals, LLC Country of Publication: United States NLM ID: 101508617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1945-4589 (Electronic) Linking ISSN: 19454589 NLM ISO Abbreviation: Aging (Albany NY) Subsets: MEDLINE
مواضيع طبية MeSH: Bone Marrow*/metabolism , Bone Marrow*/pathology, Aging/*physiology , Bone Resorption/*metabolism , Megakaryocytes/*physiology , Osteogenesis/*physiology , RANK Ligand/*metabolism , Receptors, Thrombopoietin/*metabolism , Thrombopoietin/*metabolism, Age Factors ; Animals ; Cell Differentiation ; Cell Proliferation ; Estrogens/metabolism ; Mice ; Sex Factors ; Signal Transduction/physiology
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6دورية أكاديمية
المؤلفون: Maupin KA; Program for Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI, USA., Dick D; Program for Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI, USA., Lee J; Program for Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI, USA., Williams BO; Program for Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI, USA. bart.williams@vai.org.
المصدر: Calcified tissue international [Calcif Tissue Int] 2020 Mar; Vol. 106 (3), pp. 283-293. Date of Electronic Publication: 2019 Nov 19.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7905481 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0827 (Electronic) Linking ISSN: 0171967X NLM ISO Abbreviation: Calcif Tissue Int Subsets: MEDLINE
مواضيع طبية MeSH: Cortical Bone*/diagnostic imaging , Cortical Bone*/drug effects, Galectin 3/*genetics , Osteoporosis/*etiology, Androgens/pharmacology ; Animals ; Body Composition ; Cancellous Bone/diagnostic imaging ; Cancellous Bone/drug effects ; Castration ; Dihydrotestosterone/pharmacology ; Estrogens/pharmacology ; Female ; Male ; Mice ; Mice, Knockout ; Osteoporosis/diagnostic imaging ; Osteoporosis/genetics
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7دورية أكاديمية
المؤلفون: Maupin KA; Indiana University School of Medicine, Indiana, USA., Himes ER; Indiana University School of Medicine, Indiana, USA., Plett AP; Indiana University School of Medicine, Indiana, USA., Chua HL; Indiana University School of Medicine, Indiana, USA., Singh P; Indiana University School of Medicine, Indiana, USA., Ghosh J; Indiana University School of Medicine, Indiana, USA., Mohamad SF; Indiana University School of Medicine, Indiana, USA., Abeysekera I; Indiana University School of Medicine, Indiana, USA., Fisher A; Indiana University School of Medicine, Indiana, USA., Sampson C; Indiana University School of Medicine, Indiana, USA., Hong JM; Indiana University School of Dentistry, Indiana, USA., Childress P; Indiana University School of Medicine, Indiana, USA., Alvarez M; Indiana University School of Medicine, Indiana, USA., Srour EF; Indiana University School of Medicine, Indiana, USA., Bruzzaniti A; Indiana University School of Dentistry, Indiana, USA., Pelus LM; Indiana University School of Medicine, Indiana, USA., Orschell CM; Indiana University School of Medicine, Indiana, USA., Kacena MA; Indiana University School of Medicine, Indiana, USA. Electronic address: mkacena@iupui.edu.
المصدر: Bone [Bone] 2019 Oct; Vol. 127, pp. 452-459. Date of Electronic Publication: 2019 Jul 09.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural
بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8504048 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2763 (Electronic) Linking ISSN: 18732763 NLM ISO Abbreviation: Bone Subsets: MEDLINE
مواضيع طبية MeSH: Aging/*physiology , Bone and Bones/*anatomy & histology , Megakaryocytes/*cytology , Osteoblasts/*cytology, Adoptive Transfer ; Animals ; Bone Marrow/metabolism ; Bone and Bones/diagnostic imaging ; Cell Count ; Cell Proliferation ; GATA1 Transcription Factor/metabolism ; Hematopoietic Stem Cells/metabolism ; Male ; Mice, Inbred C57BL ; Organ Size ; Phenotype ; X-Ray Microtomography
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8دورية أكاديمية
المؤلفون: Maupin KA; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA., Childress P; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA.; 2Richard L. Roudebush VA Medical Center, Indianapolis, IN USA., Brinker A; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA., Khan F; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA., Abeysekera I; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA., Aguilar IN; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA., Olivos DJ 3rd; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA.; 3Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN USA.; 4Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN USA., Adam G; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA., Savaglio MK; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA., Ganesh V; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA., Gorden R; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA., Mannfeld R; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA., Beckner E; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA., Horan DJ; 2Richard L. Roudebush VA Medical Center, Indianapolis, IN USA.; 5Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN USA., Robling AG; 2Richard L. Roudebush VA Medical Center, Indianapolis, IN USA.; 5Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN USA., Chakraborty N; 6U.S. Army Center for Environmental Health Research, Fort Detrick, MD USA.; 7Geneva Foundation, Fort Detrick, MD USA., Gautam A; 7Geneva Foundation, Fort Detrick, MD USA., Hammamieh R; 7Geneva Foundation, Fort Detrick, MD USA., Kacena MA; 1Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN USA.; 2Richard L. Roudebush VA Medical Center, Indianapolis, IN USA.; 5Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN USA.
المصدر: NPJ microgravity [NPJ Microgravity] 2019 Sep 24; Vol. 5, pp. 21. Date of Electronic Publication: 2019 Sep 24 (Print Publication: 2019).
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Springer Nature Country of Publication: United States NLM ID: 101703605 Publication Model: eCollection Cited Medium: Print ISSN: 2373-8065 (Print) Linking ISSN: 23738065 NLM ISO Abbreviation: NPJ Microgravity Subsets: PubMed not MEDLINE
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9دورية أكاديمية
المؤلفون: Dadwal UC; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.; Richard L. Roudebush VA Medical Center, Indianapolis, IN, USA., Maupin KA; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA., Zamarioli A; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.; Ribeirão Preto Medical School, Ribeirão Preto, SP, Brazil., Tucker A; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA., Harris JS; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA., Fischer JP; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA., Rytlewski JD; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA., Scofield DC; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA., Wininger AE; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA., Bhatti FUR; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.; Richard L. Roudebush VA Medical Center, Indianapolis, IN, USA., Alvarez M; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.; Richard L. Roudebush VA Medical Center, Indianapolis, IN, USA., Childress PJ; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.; Richard L. Roudebush VA Medical Center, Indianapolis, IN, USA., Chakraborty N; U.S. Army Center for Environmental Health Research, Fort Detrick, MD, USA.; Geneva Foundation, Fort Detrick, MD, USA., Gautam A; U.S. Army Center for Environmental Health Research, Fort Detrick, MD, USA., Hammamieh R; U.S. Army Center for Environmental Health Research, Fort Detrick, MD, USA., Kacena MA; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA. mkacena@iupui.edu.; Richard L. Roudebush VA Medical Center, Indianapolis, IN, USA. mkacena@iupui.edu.
المصدر: Scientific reports [Sci Rep] 2019 Aug 06; Vol. 9 (1), pp. 11419. Date of Electronic Publication: 2019 Aug 06.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
مواضيع طبية MeSH: Space Flight*, Bone Density/*physiology , Fracture Healing/*physiology , Fractures, Bone/*surgery, Animals ; Disease Models, Animal ; Female ; Femur/diagnostic imaging ; Femur/physiology ; Fractures, Bone/diagnostic imaging ; Fractures, Bone/physiopathology ; Humans ; Male ; Mandible/diagnostic imaging ; Mandible/physiology ; Mice ; Tibia/diagnostic imaging ; Tibia/physiology ; Weight-Bearing/physiology ; X-Ray Microtomography
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10دورية أكاديمية
المؤلفون: Alvarez MB; 1 Department of Orthopaedic Surgery, Indiana University School of Medicine , Indianapolis, Indiana., Xu L; 2 Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana., Childress PJ; 1 Department of Orthopaedic Surgery, Indiana University School of Medicine , Indianapolis, Indiana., Maupin KA; 1 Department of Orthopaedic Surgery, Indiana University School of Medicine , Indianapolis, Indiana., Mohamad SF; 2 Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana., Chitteti BR; 2 Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana., Himes E; 1 Department of Orthopaedic Surgery, Indiana University School of Medicine , Indianapolis, Indiana., Olivos DJ 3rd; 1 Department of Orthopaedic Surgery, Indiana University School of Medicine , Indianapolis, Indiana., Cheng YH; 1 Department of Orthopaedic Surgery, Indiana University School of Medicine , Indianapolis, Indiana., Conway SJ; 3 Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine , Indianapolis, Indiana., Srour EF; 2 Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana.; 3 Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine , Indianapolis, Indiana., Kacena MA; 1 Department of Orthopaedic Surgery, Indiana University School of Medicine , Indianapolis, Indiana.
المصدر: Stem cells and development [Stem Cells Dev] 2018 May 15; Vol. 27 (10), pp. 671-682.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101197107 Publication Model: Print Cited Medium: Internet ISSN: 1557-8534 (Electronic) Linking ISSN: 15473287 NLM ISO Abbreviation: Stem Cells Dev Subsets: MEDLINE
مواضيع طبية MeSH: Hematopoiesis/*physiology , Hematopoietic Stem Cells/*cytology , Megakaryocytes/*cytology , Osteoblasts/*cytology, Animals ; Cells, Cultured ; Coculture Techniques/methods ; Female ; Hematopoietic Stem Cells/metabolism ; Male ; Megakaryocytes/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Osteoblasts/metabolism ; Thrombopoietin/metabolism