المؤلفون: Nadezhda Dyrkheeva, Rashid Anarbaev, Natalia Lebedeva, Maxim Kuprushkin, Alexandra Kuznetsova, Nikita Kuznetsov, Nadejda Rechkunova, Olga Lavrik

المصدر: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

مصطلحات موضوعية: tyrosyl-DNA phosphodiesterase 1, 3′-phosphoglycolate, glycerol, alcohol, ethanol, spinocerebellar ataxia with axonal neuropathy type 1, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2020.604732/full; https://doaj.org/toc/2296-634X

URL الوصول: https://doaj.org/article/40520c18ecda4b93b43b6f07b7ba2575

المؤلفون: Alexandra Kuznetsova, Nadejda I. Rechkunova, N. K. Lebedeva, Nadezhda S Dyrkheeva, Maxim Kuprushkin, Rashid O. Anarbaev, Olga I. Lavrik, Nikita A. Kuznetsov

المصدر: Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, DNA repair, DNA damage, glycerol, Primary alcohol, 03 medical and health sciences, chemistry.chemical_compound, Cell and Developmental Biology, lcsh:QH301-705.5, Original Research, 030102 biochemistry & molecular biology, Phospholipase D, alcohol, Cell Biology, Tyrosyl-DNA Phosphodiesterase 1, 3′-phosphoglycolate, tyrosyl-DNA phosphodiesterase 1, 030104 developmental biology, chemistry, lcsh:Biology (General), Phosphodiester bond, ethanol, TDP1, DNA, Developmental Biology, spinocerebellar ataxia with axonal neuropathy type 1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7187af36819af31a1baf1c43e0d410b1
https://pubmed.ncbi.nlm.nih.gov/33425909

المؤلفون: Nariman F. Salakhutdinov, D. K. Nilov, Alexandra L. Zakharenko, Olga I. Lavrik, Olga A. Luzina, Maxim Kuprushkin, Aleksandr Filimonov, I. V. Gushchina, Ekaterina S Ilina, Olga D. Zakharova, Vytas K. Švedas, Nadezhda S Dyrkheeva

المصدر: Planta medica. 85(2)

مصطلحات موضوعية: Phosphodiesterase Inhibitors, Pharmaceutical Science, Context (language use), 01 natural sciences, Analytical Chemistry, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, Escherichia coli, Moiety, Humans, MTT assay, Benzofurans, Pharmacology, biology, 010405 organic chemistry, Phosphoric Diester Hydrolases, Topoisomerase, Organic Chemistry, Usnic acid, Phosphodiesterase, Biological activity, Tyrosyl-DNA Phosphodiesterase 1, 0104 chemical sciences, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, HEK293 Cells, Complementary and alternative medicine, chemistry, Biochemistry, biology.protein, MCF-7 Cells, Molecular Medicine, Microorganisms, Genetically-Modified

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661ba7647700609c99f40817c53436e1
https://pubmed.ncbi.nlm.nih.gov/30142660

المؤلفون: Olga D. Zakharova, Maxim Kuprushkin, Ivanhoe K. H. Leung, Jinal Patel, Raina Chand, Olga I. Lavrik, Nadezhda S Dyrkheeva, D. S. Khachatryan, Jóhannes Reynisson, N.F. Salakhutdinov, Arina A Chepanova, Aleksander S Filimonov, Daniel M Ayine-Tora, A. V. Kolotaev, Alexandra L. Zakharenko, Konstantin P. Volcho, Ekaterina S Ilina, Olga A. Luzina

المصدر: Molecules, Vol 24, Iss 20, p 3711 (2019)
Molecules
Volume 24
Issue 20

مصطلحات موضوعية: Models, Molecular, Phosphodiesterase Inhibitors, Molecular Conformation, Pharmaceutical Science, Pharmacology, 01 natural sciences, Analytical Chemistry, chemistry.chemical_compound, Drug Discovery, QD, media_common, 0303 health sciences, Molecular Structure, biology, Chemistry, Usnic acid, Phosphodiesterase, Combination chemotherapy, topoisomerase 1, inhibiting activity, Chemistry (miscellaneous), Molecular Medicine, Pharmacophore, Protein Binding, medicine.drug, Drug, Cell Survival, media_common.quotation_subject, tyrosyl-dna phosphodiesterase 1 (tdp1), Article, lcsh:QD241-441, Structure-Activity Relationship, 03 medical and health sciences, topotecan, lcsh:Organic chemistry, medicine, Humans, Structure–activity relationship, Physical and Theoretical Chemistry, Benzofurans, 030304 developmental biology, Dose-Response Relationship, Drug, Phosphoric Diester Hydrolases, molecular modeling, 010405 organic chemistry, Topoisomerase, usnic acid, Organic Chemistry, synergetic effect, 0104 chemical sciences, Thiazoles, biology.protein, Topotecan

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179759de17dd21c07501413d260618e8
https://doi.org/10.3390/molecules24203711