نتائج البحث - "Maxim M, Bespalov"

المساهمون: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, Division of Pharmacology and Pharmacotherapy, Regenerative pharmacology group, Regenerative Neuroscience, Centre of Excellence in Stem Cell Metabolism, STEMM - Stem Cells and Metabolism Research Program, Drug Research Program, Timo Petteri Piepponen / Principal Investigator, Mart Saarma / Principal Investigator

المصدر: Movement Disorders

مصطلحات موضوعية: 0301 basic medicine, receptor tyrosine kinase RET agonist, Dopamine, Neurturin, Parkinson's disease, GENE DELIVERY, Mice, DOUBLE-BLIND, 0302 clinical medicine, PARKINSONS-DISEASE, Neurotrophic factors, Glial cell line-derived neurotrophic factor, Clustered Regularly Interspaced Short Palindromic Repeats, Research Articles, NEUROPROTECTION, glial cell line‐derived neurotrophic factor (GDNF), SUBSTANTIA-NIGRA, biology, Chemistry, Neurodegeneration, INFUSION, Parkinson Disease, dopamine neurons, 3. Good health, Cell biology, Substantia Nigra, Neurology, medicine.drug, Research Article, Agonist, Glial Cell Line-Derived Neurotrophic Factor Receptors, medicine.drug_class, Substantia nigra, Neuroprotection, 03 medical and health sciences, FACTOR GDNF, medicine, Animals, GFR-ALPHA-1, Glial Cell Line-Derived Neurotrophic Factor, Parkinson Disease, Secondary, Oxidopamine, CRISPR associated protein 9, Dopaminergic Neurons, Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated protein 9, glial cell line-derived neurotrophic factor (GDNF), 3112 Neurosciences, medicine.disease, Corpus Striatum, MODEL, 030104 developmental biology, nervous system, biology.protein, Neurology (clinical), NEURTURIN, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e84d74f4678924375a4685dbc5c959
http://hdl.handle.net/10138/320194

6

Human pluripotent reprogramming with CRISPR activators

المؤلفون: Ras Trokovic, Eeva-Mari Jouhilahti, Juha Kere, Jere Weltner, Diego Balboa, Maxim M. Bespalov, Kaarel Krjutškov, Shintaro Katayama, Timo Otonkoski

المساهمون: Centre of Excellence in Stem Cell Metabolism, Research Programs Unit, Research Programme for Molecular Neurology, Juha Kere / Principal Investigator, Children's Hospital, Timo Pyry Juhani Otonkoski / Principal Investigator, Clinicum, Lastentautien yksikkö, HUS Children and Adolescents

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Weltner, J, Balboa, D, Katayama, S, Bespalov, M, Krjutškov, K, Jouhilahti, E M, Trokovic, R, Kere, J & Otonkoski, T 2018, ' Human pluripotent reprogramming with CRISPR activators ', Nature Communications, vol. 9, no. 1, 2643, pp. 1-12 . https://doi.org/10.1038/s41467-018-05067-x
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, Transcription, Genetic, General Physics and Astronomy, 0302 clinical medicine, Neural Stem Cells, CRISPR-Associated Protein 9, MEDIATED REGULATION, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Induced pluripotent stem cell, lcsh:Science, Genetics, 0303 health sciences, Multidisciplinary, Gene Expression Regulation, Developmental, Nanog Homeobox Protein, Cellular Reprogramming, Cell biology, GENOME, DIFFERENTIATION, KLF4, embryonic structures, Stem cell, STEM-CELLS, Reprogramming, RNA, Guide, Kinetoplastida, EXPRESSION, Homeobox protein NANOG, FIBROBLASTS, REGULATORY ELEMENTS, Science, Rex1, Induced Pluripotent Stem Cells, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Kruppel-Like Factor 4, 03 medical and health sciences, SOX2, Alu Elements, Humans, Nucleotide Motifs, 030304 developmental biology, Base Sequence, Cas9, General Chemistry, Embryo, Mammalian, SINGLE-CELL TRANSCRIPTOME, ENHANCERS, HEK293 Cells, 030104 developmental biology, lcsh:Q, 3111 Biomedicine, 030217 neurology & neurosurgery, GENERATION

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1627a30ced3a13269de8ff17a45ce416
http://link.springer.com/article/10.1038/s41467-018-05067-x

Find this article in full text from ProQuest

7

Comparison of liquid chromatography-mass spectrometry and direct infusion microchip electrospray ionization mass spectrometry in global metabolomics of cell samples

المؤلفون: Risto Kostiainen, Päivi Pöhö, Maxim M. Bespalov, Tapio Kotiaho, Tiina Sikanen, Katriina Lipponen

المساهمون: Division of Pharmaceutical Chemistry and Technology, Divisions of Faculty of Pharmacy, Drug Research Program, STEMM - Stem Cells and Metabolism Research Program, Centre of Excellence in Stem Cell Metabolism, Tiina Sikanen / Chemical Microsystems Lab, Tapio Kotiaho / Principal Investigator, Department of Chemistry, Risto Kostiainen / Principal Investigator

مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, Electrospray, Electrospray ionization, Cells, Induced Pluripotent Stem Cells, Cell, 116 Chemical sciences, Microchip, Pharmaceutical Science, Ion suppression in liquid chromatography–mass spectrometry, 02 engineering and technology, Mass spectrometry, 030226 pharmacology & pharmacy, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Metabolomics, Liquid chromatography–mass spectrometry, medicine, Direct infusion mass spectrometry, Humans, Liquid chromatography-mass spectrometry, Chromatography, High Pressure Liquid, Chromatography, Chemistry, Small sample, MS, Fibroblasts, 021001 nanoscience & nanotechnology, medicine.anatomical_structure, 317 Pharmacy, DISCOVERY, Metabolome, 0210 nano-technology, STEM-CELLS