المؤلفون: Ashworth, Alan, McDade, SS, Henry, AE, Pivato, GP, Kozarewa, I, Mitsopoulos, C, Fenwick, K, Assiotis, I, Hakas, J, Zvelebil, M, Orr, N

URL الوصول: https://escholarship.org/uc/item/4179q2xw

المؤلفون: Corry, SM, McCorry, AMB, Lannagan, TRM, Leonard, NA, Fisher, NC, Byrne, RM, Tsantoulis, P, Cortes-Lavaud, X, Amirkhah, R, Redmond, KL, McCooey, AJ, Malla, SB, Rogan, E, Sakhnevych, S, Gillespie, MA, White, M, Richman, SD, Jackstadt, R-F, Campbell, AD, Maguire, S, S:CORT and ACRCelerate consortia, McDade, SS, Longley, DB, Loughrey, MB, Coleman, HG, Kerr, EM, Tejpar, S, Maughan, T, Leedham, SJ, Small, DM, Ryan, AE, Sansom, OJ, Lawler, M, Dunne, PD

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::804014afd058d973a5ee285f53d67e53
https://eprints.whiterose.ac.uk/186302/6/gutjnl-2021-326183.full.pdf

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المؤلفون: Roy Chaudhuri T; Department of Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, New York., Lin Q; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Stachowiak EK; Department of Pathology and Anatomical Sciences, University at Buffalo, State University of New York, Buffalo, New York., Rosario SR; Department of Bioinformatics and Biostatistics, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Spernyak JA; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Ma WW; Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio., Stachowiak MK; Department of Pathology and Anatomical Sciences, University at Buffalo, State University of New York, Buffalo, New York., Greene MK; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom., Quinn GP; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom., McDade SS; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom., Clynes M; The National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland., Scott CJ; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom., Straubinger RM; Department of Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, New York.; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Apr 01; Vol. 30 (7), pp. 1367-1381.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Pancreatic Neoplasms*/drug therapy , Pancreatic Neoplasms*/genetics , Pancreatic Neoplasms*/metabolism , Carcinoma, Pancreatic Ductal*/drug therapy , Carcinoma, Pancreatic Ductal*/genetics , Carcinoma, Pancreatic Ductal*/metabolism, Humans ; Animals ; Heterografts ; Hedgehog Proteins/genetics ; Hedgehog Proteins/metabolism ; Signal Transduction ; Disease Models, Animal ; Cell Line, Tumor

المؤلفون: Abed A; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7AE, United Kingdom.; Pharmacological and Diagnostic Research Centre, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman 19111, Jordan., Greene MK; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7AE, United Kingdom., Alsa'd AA; Pharmacological and Diagnostic Research Centre, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman 19111, Jordan.; School of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, United Kingdom., Lees A; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7AE, United Kingdom., Hindley A; Clinical Haematology, Belfast City Hospital, 97 Lisburn Road, Belfast, BT9 7AB, United Kingdom., Longley DB; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7AE, United Kingdom., McDade SS; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7AE, United Kingdom., Scott CJ; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7AE, United Kingdom.

المصدر: Molecular pharmaceutics [Mol Pharm] 2024 Mar 04; Vol. 21 (3), pp. 1246-1255. Date of Electronic Publication: 2024 Feb 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Histone Deacetylase Inhibitors*/pharmacology , Histone Deacetylase Inhibitors*/therapeutic use , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use , Benzamides* , Pyridines* , Pyrrolidines* , para-Aminobenzoates*, Humans ; Animals ; Mice ; Tumor Suppressor Protein p53/metabolism ; Apoptosis ; Cell Line, Tumor ; Drug Combinations ; Proto-Oncogene Proteins c-mdm2

المؤلفون: Sessler T; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Quinn GP; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Wappett M; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Rogan E; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Sharkey D; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Ahmaderaghi B; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Lawler M; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Longley DB; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., McDade SS; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK. s.mcdade@qub.ac.uk.

المصدر: Scientific reports [Sci Rep] 2023 Dec 13; Vol. 13 (1), pp. 22093. Date of Electronic Publication: 2023 Dec 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Software* , Neoplasms*/genetics, Humans ; Survival Analysis ; Kaplan-Meier Estimate

المؤلفون: Taylor K; Division of Medical Oncology & Haematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, Northern Ireland, UK., Zou J; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Magalhaes M; Division of Medical Oncology & Haematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Oliva M; Division of Medical Oncology & Haematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Spreafico A; Division of Medical Oncology & Haematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Hansen AR; Division of Medical Oncology & Haematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., McDade SS; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, Northern Ireland, UK., Coyle VM; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, Northern Ireland, UK., Lawler M; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, Northern Ireland, UK., Elimova E; Division of Medical Oncology & Haematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Bratman SV; Department of Radiation Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Siu LL; Division of Medical Oncology & Haematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada. Electronic address: lillian.siu@uhn.ca.

المصدر: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2023 Jul; Vol. 188, pp. 29-38. Date of Electronic Publication: 2023 Apr 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0852 (Electronic) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Circulating Tumor DNA*/genetics , Head and Neck Neoplasms*/drug therapy , Head and Neck Neoplasms*/genetics , Neoplasms, Squamous Cell*, Humans ; Squamous Cell Carcinoma of Head and Neck/drug therapy ; Squamous Cell Carcinoma of Head and Neck/genetics ; Kinetics ; Biomarkers, Tumor/genetics ; Neoplasm Recurrence, Local/genetics

المؤلفون: Steiner I; Prostate Oncobiology Group, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK., Flores-Tellez TDNJ; Prostate Oncobiology Group, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK., Mevel R; Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK., Ali A; Prostate Oncobiology Group, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK; Belfast-Manchester Movember Centre of Excellence, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK., Wang P; Prostate Oncobiology Group, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK., Schofield P; Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK., Behan C; Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK., Forsythe N; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, BT9 7BL Northern Ireland, UK; Belfast-Manchester Movember Centre of Excellence, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK., Ashton G; Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK., Taylor C; The Christie NHS Foundation Trust, Manchester Academic Health Sciences Centre, M20 4BX Manchester, UK., Mills IG; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, BT9 7BL Northern Ireland, UK; Belfast-Manchester Movember Centre of Excellence, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK; Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, OX3 9DU Oxford, UK; Department of Clinical Sciences and Centre for Cancer Biomarkers, University of Bergen, 7804 Bergen, Norway., Oliveira P; Department of Pathology, The Christie NHS Foundation Trust, M20 4BX Manchester, UK., McDade SS; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, BT9 7BL Northern Ireland, UK; Belfast-Manchester Movember Centre of Excellence, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK., Zaiss DM; Department of Immune Medicine, University Regensburg, Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, and Leibniz Institute for Immunotherapy (LIT), 93053 Regensburg, Germany., Choudhury A; The Christie NHS Foundation Trust, Manchester Academic Health Sciences Centre, M20 4BX Manchester, UK; The University of Manchester, Manchester Cancer Research Centre, M20 4BX Manchester, UK; Belfast-Manchester Movember Centre of Excellence, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK., Lacaud G; Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK., Baena E; Prostate Oncobiology Group, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK; Belfast-Manchester Movember Centre of Excellence, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, SK10 4TG Macclesfield, UK. Electronic address: esther.baena@cruk.manchester.ac.uk.

المصدر: Cell reports [Cell Rep] 2023 Apr 25; Vol. 42 (4), pp. 112377. Date of Electronic Publication: 2023 Apr 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Androgens*/metabolism , Prostatic Neoplasms, Castration-Resistant*/metabolism, Animals ; Male ; Mice ; Androgen Antagonists/pharmacology ; Cell Adhesion Molecules/metabolism ; Cell Line, Tumor ; GPI-Linked Proteins/metabolism ; Mitogen-Activated Protein Kinases/metabolism ; Prostate/metabolism ; Receptors, Androgen/metabolism

المؤلفون: McCabe A; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.; The SFI Centre for Research Training in Genomics Data Science, Galway, Ireland., Zaheed O; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.; The SFI Centre for Research Training in Genomics Data Science, Galway, Ireland., McDade SS; The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, Northern Ireland, United Kingdom., Dean K; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.

المصدر: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2023 Feb 13; Vol. 11, pp. 1104514. Date of Electronic Publication: 2023 Feb 13 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE

المؤلفون: Khawaja H; Drug Resistance Group, Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, United Kingdom., Briggs R; Drug Resistance Group, Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, United Kingdom., Latimer CH; Drug Resistance Group, Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, United Kingdom., Rassel M; Drug Resistance Group, Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, United Kingdom., Griffin D; Drug Resistance Group, Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, United Kingdom., Hanson L; AstraZeneca, Cambridge, United Kingdom., Bardelli A; Department of Oncology, University of Torino, Candiolo, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Torino, Italy., Di Nicolantonio F; Department of Oncology, University of Torino, Candiolo, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Torino, Italy., McDade SS; Drug Resistance Group, Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, United Kingdom., Scott CJ; Drug Resistance Group, Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, United Kingdom., Lambe S; Drug Resistance Group, Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, United Kingdom., Maurya M; Precision Medicine Centre of Excellence, Health Sciences Building, Queen's University Belfast, Belfast, United Kingdom., Lindner AU; Centre of Systems Medicine, Royal College of Surgeons in Ireland University of Medicine and Health Sciences, Dublin 2, Ireland., Prehn JHM; Centre of Systems Medicine, Royal College of Surgeons in Ireland University of Medicine and Health Sciences, Dublin 2, Ireland., Sousa J; Drug Resistance Group, Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, United Kingdom.; Personal Health Data Science Group, Sano. Centre for Computational Personalised Medicine, Krakow, Poland., Winnington C; Drug Resistance Group, Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, United Kingdom., LaBonte MJ; Drug Resistance Group, Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, United Kingdom., Ross S; AstraZeneca, Cambridge, United Kingdom., Van Schaeybroeck S; Drug Resistance Group, Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, United Kingdom.

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2023 Jan 03; Vol. 22 (1), pp. 135-149.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/genetics, Humans ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins p21(ras)/genetics ; Proto-Oncogene Proteins p21(ras)/metabolism ; Cell Line, Tumor ; Apoptosis ; bcl-X Protein/genetics ; bcl-X Protein/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism