المؤلفون: McKay NS; Mallinckrodt Institute of Radiology, Washington University School of Medicine., Millar PR; Department of Neurology, Washington University School of Medicine., Nicosia J; Department of Neurology, Washington University School of Medicine., Aschenbrenner AJ; Department of Neurology, Washington University School of Medicine., Gordon BA; Mallinckrodt Institute of Radiology, Washington University School of Medicine., Benzinger TLS; Mallinckrodt Institute of Radiology, Washington University School of Medicine., Cruchaga CC; Department of Psychiatry, Washington University School of Medicine., Schindler SE; Department of Neurology, Washington University School of Medicine., Morris JC; Department of Neurology, Washington University School of Medicine., Hassenstab J; Department of Neurology, Washington University School of Medicine.

المصدر: Neuropsychology [Neuropsychology] 2024 Jul; Vol. 38 (5), pp. 443-464. Date of Electronic Publication: 2024 Apr 11.

نوع المنشور: Journal Article; Comparative Study

بيانات الدورية: Publisher: American Psychological Association Country of Publication: United States NLM ID: 8904467 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1931-1559 (Electronic) Linking ISSN: 08944105 NLM ISO Abbreviation: Neuropsychology Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/psychology , Neuropsychological Tests*, Humans ; Female ; Male ; Aged ; Aged, 80 and over ; Attention/physiology ; Middle Aged ; Memory, Episodic ; Memory, Short-Term/physiology ; Cognition/physiology ; Cognitive Dysfunction/diagnosis

المؤلفون: Wisch JK; Department of Neurology, Washington University in St Louis, St Louis, MO, USA. Electronic address: julie.wisch@wustl.edu., McKay NS; Department of Radiology, Washington University in St Louis, St Louis, MO, USA., Boerwinkle AH; McGovern Medical School, University of Texas in Houston, Houston, TX, USA., Kennedy J; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Flores S; Department of Radiology, Washington University in St Louis, St Louis, MO, USA., Handen BL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Christian BT; Department of Medical Physics and Psychiatry, University of Wisconsin-Madison, Madison, WI, USA., Head E; Department of Pathology, Gillespie Neuroscience Research Facility, University of California, Irvine, CA, USA., Mapstone M; Department of Neurology, University of California Irvine School of Medicine, Irvine, CA, USA., Rafii MS; Alzheimer's Therapeutic Research Institute, Keck School of Medicine of USC, Los Angeles, CA, USA., O'Bryant SE; Institute for Translational Research Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA., Price JC; Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA., Laymon CM; Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA., Krinsky-McHale SJ; Department of Psychology, New York State Institute for Basic Research in Developmental Disabilities, New York, NY, USA., Lai F; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA., Rosas HD; Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA., Hartley SL; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA., Zaman S; Cambridge Intellectual and Developmental Disabilities Research Group, University of Cambridge, Cambridge, UK., Lott IT; Department of Pediatrics, University of California Irvine School of Medicine, Irvine, CA, USA., Tudorascu D; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Zammit M; Department of Medical Physics and Psychiatry, University of Wisconsin-Madison, Madison, WI, USA., Brickman AM; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Lee JH; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA; Department of Epidemiology, Columbia University Irving Medical Center, New York, NY, USA., Bird TD; Department of Neurology, University of Washington, Seattle, WA, USA., Cohen A; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Chrem P; Centro de Memoria y Envejecimiento, Buenos Aires, Argentina., Daniels A; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Chhatwal JP; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA., Cruchaga C; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA; Hope Center for Neurological Disorders, Washington University in St Louis, St Louis, MO, USA., Ibanez L; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA., Jucker M; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Karch CM; Department of Neurology, Washington University in St Louis, St Louis, MO, USA; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA; German Center for Neurodegenerative Diseases, Tübingen, Germany., Day GS; Department of Neurology, Mayo Clinic Florida, Jacksonville, FL, USA., Lee JH; Department of Neurology, University of Ulsan College of Medicine, Asian Medical Center, Seoul, South Korea., Levin J; Department of Neurology, LMU University Hospital, LMU Munich, Munich, Germany; German Center for Neurodegenerative Diseases, site Munich, Munich, Germany; Munich Cluster for Systems Neurology, Munich, Germany., Llibre-Guerra J; Hope Center for Neurological Disorders, Washington University in St Louis, St Louis, MO, USA., Li Y; Department of Neurology, Washington University in St Louis, St Louis, MO, USA; Department of Biostatistics, Washington University in St Louis, St Louis, MO, USA., Lopera F; Grupo de Neurociencias de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia., Roh JH; Departments of Physiology and Neurology, Korea University College of Medicine, Seoul, South Korea., Ringman JM; Alzheimer's Therapeutic Research Institute, Keck School of Medicine of USC, Los Angeles, CA, USA., Supnet-Bell C; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., van Dyck CH; School of Medicine, Yale University, New Haven, CT, USA., Xiong C; Department of Biostatistics, Washington University in St Louis, St Louis, MO, USA., Wang G; Department of Neurology, Washington University in St Louis, St Louis, MO, USA; Department of Biostatistics, Washington University in St Louis, St Louis, MO, USA., Morris JC; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., McDade E; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Bateman RJ; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Benzinger TLS; Department of Radiology, Washington University in St Louis, St Louis, MO, USA., Gordon BA; Department of Radiology, Washington University in St Louis, St Louis, MO, USA., Ances BM; Department of Neurology, Washington University in St Louis, St Louis, MO, USA.

مؤلفون مشاركون: Alzheimer's Biomarker Consortium-Down syndrome, Dominantly Inherited Alzheimer Network

المصدر: The Lancet. Neurology [Lancet Neurol] 2024 May; Vol. 23 (5), pp. 500-510.

نوع المنشور: Observational Study; Journal Article

بيانات الدورية: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 101139309 Publication Model: Print Cited Medium: Internet ISSN: 1474-4465 (Electronic) Linking ISSN: 14744422 NLM ISO Abbreviation: Lancet Neurol Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/genetics , Down Syndrome* , Cognitive Dysfunction*/pathology, Male ; Female ; Humans ; Adult ; Cross-Sectional Studies ; Amyloid beta-Peptides/metabolism ; tau Proteins/metabolism ; Amyloid ; Magnetic Resonance Imaging/methods ; Positron-Emission Tomography/methods

المؤلفون: Joseph-Mathurin N; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Feldman RL; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Lu R; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Shirzadi Z; Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Toomer C; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA.; Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Saint Clair JR; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA.; Meharry School of Medicine, Meharry College, Nashville, Tennessee, USA., Ma Y; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., McKay NS; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Strain JF; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Kilgore C; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Friedrichsen KA; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Chen CD; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Gordon BA; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Chen G; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Hornbeck RC; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Massoumzadeh P; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., McCullough AA; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Wang Q; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Li Y; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Wang G; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Keefe SJ; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Schultz SA; Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Cruchaga C; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Preboske GM; Mayo Clinic, Rochester, Minnesota, USA., Jack CR Jr; Mayo Clinic, Rochester, Minnesota, USA., Llibre-Guerra JJ; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Allegri RF; Institute for Neurological Research FLENI, Montañeses, Buenos Aires, Argentina., Ances BM; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Berman SB; University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA., Brooks WS; Neuroscience Research Australia, Sydney, NSW, Australia.; University of New South Wales, Sydney, NSW, Australia., Cash DM; UK Dementia Research Institute and Dementia Research Centre, UCL Queen Square Institute of Neurology, University College London, London, UK., Day GS; Mayo Clinic, Jacksonville, Florida, USA., Fox NC; UK Dementia Research Institute and Dementia Research Centre, UCL Queen Square Institute of Neurology, University College London, London, UK., Fulham M; Royal Prince Alfred Hospital, Camperdown, NSW, Australia., Ghetti B; Indiana University School of Medicine, Indianapolis, Indiana, USA., Johnson KA; Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Jucker M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Klunk WE; University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA., la Fougère C; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; University hospital Tübingen, Tübingen, Germany., Levin J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Ludwig Maximilian University of Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Niimi Y; The University of Tokyo, Bunkyo City, Tokyo, Japan., Oh H; Brown University, Providence, Rhode Island, USA., Perrin RJ; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Reischl G; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; University hospital Tübingen, Tübingen, Germany., Ringman JM; Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Saykin AJ; Indiana University School of Medicine, Indianapolis, Indiana, USA., Schofield PR; Neuroscience Research Australia, Sydney, NSW, Australia.; University of New South Wales, Sydney, NSW, Australia., Su Y; Banner Alzheimer Institute, Banner Health, Phoenix, Arizona, USA., Supnet-Bell C; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Vöglein J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Ludwig Maximilian University of Munich, Munich, Germany., Yakushev I; Department of Nuclear Medicine, Technical University of Munich, Munich, Germany., Brickman AM; Columbia University Medical Center, New York, New York, USA., Morris JC; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., McDade E; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Xiong C; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Bateman RJ; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA., Chhatwal JP; Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Benzinger TLS; Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA.

مؤلفون مشاركون: Dominantly Inherited Alzheimer Network

المصدر: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Apr; Vol. 20 (4), pp. 2680-2697. Date of Electronic Publication: 2024 Feb 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/diagnostic imaging , Alzheimer Disease*/genetics , Alzheimer Disease*/pathology , Amyloidosis* , Cerebral Small Vessel Diseases*/diagnostic imaging , Cerebral Small Vessel Diseases*/genetics , Cerebral Small Vessel Diseases*/complications, Humans ; Diffusion Tensor Imaging ; Magnetic Resonance Imaging ; Mutation/genetics ; Presenilin-1/genetics

SCR Disease Name: Alzheimer disease type 1

المؤلفون: Wang Q; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Schindler SE; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Chen G; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Mckay NS; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., McCullough A; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Flores S; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Liu J; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Sun Z; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Wang S; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Wang W; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Hassenstab J; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Cruchaga C; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Perrin RJ; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Fagan AM; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Morris JC; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Wang Y; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO., Benzinger TLS; From the Mallinckrodt Institute of Radiology (Q.W., G.C., N.S.M., A.M., S.F., Y.W., T.L.S.B.), Knight Alzheimer Disease Research Center (Q.W., S.E.S., G.C., N.S.M., A.M., J.H., R.J.P., A.M.F., J.C.M., T.L.S.B.), Department of Neurology (S.E.S., J.H., C.C., A.M.F., J.C.M.), Department of Surgery (J.L.), Department of Biomedical Engineering (Z.S.), Department of Electrical and System Engineering (S.W., W.W., Y.W.), Department of Psychiatry (C.C.), Department of Pathology & Immunology (R.J.P.), Department of Obstetrics & Gynecology (Y.W.), and Department of Neurosurgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO.

المصدر: Neurology [Neurology] 2024 Feb; Vol. 102 (4), pp. e208013. Date of Electronic Publication: 2024 Feb 05.

نوع المنشور: Observational Study; Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/pathology , White Matter*/diagnostic imaging , White Matter*/pathology , Cognitive Dysfunction*, Humans ; Female ; Aged ; Male ; Cross-Sectional Studies ; Retrospective Studies ; tau Proteins ; Neuroinflammatory Diseases ; Biomarkers ; Amyloid beta-Peptides ; Peptide Fragments

المؤلفون: Chen G; Departments of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., McKay NS; Departments of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Gordon BA; Departments of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Liu J; Department of Surgery, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Joseph-Mathurin N; Departments of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Schindler SE; Department of Neurology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Hassenstab J; Department of Neurology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Aschenbrenner AJ; Knight Alzheimer's Disease Research Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Wang Q; Departments of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Schultz SA; Department of Neurology Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Su Y; Banner Alzheimer's Institute, Phoenix, AZ, USA., LaMontagne PJ; Departments of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Keefe SJ; Departments of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Massoumzadeh P; Departments of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Cruchaga C; Department of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Xiong C; Divison of Biostatistics, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Morris JC; Departments of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Benzinger TLS; Departments of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University in St. Louis School of Medicine, St. Louis, MO, USA. Electronic address: benzingert@wustl.edu.

المصدر: NeuroImage. Clinical [Neuroimage Clin] 2024; Vol. 41, pp. 103551. Date of Electronic Publication: 2023 Dec 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101597070 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-1582 (Electronic) Linking ISSN: 22131582 NLM ISO Abbreviation: Neuroimage Clin Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/diagnostic imaging , Cognitive Dysfunction*/diagnostic imaging, Humans ; Cross-Sectional Studies ; Amyloid beta-Peptides/metabolism ; Amyloid/metabolism ; Brain/diagnostic imaging ; Brain/metabolism ; Biomarkers ; Positron-Emission Tomography/methods ; Longitudinal Studies

المؤلفون: Wagemann O; Department of Neurology, Washington University St. Louis, St. Louis, Missouri, USA.; Department of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany., Li Y; Department of Biostatistics, Washington University St. Louis, St. Louis, Missouri, USA., Hassenstab J; Department of Neurology, Washington University St. Louis, St. Louis, Missouri, USA., Aschenbrenner AJ; Department of Neurology, Washington University St. Louis, St. Louis, Missouri, USA., McKay NS; Department of Radiology, Washington University St. Louis, St. Louis, Missouri, USA., Gordon BA; Department of Radiology, Washington University St. Louis, St. Louis, Missouri, USA., Benzinger TLS; Department of Radiology, Washington University St. Louis, St. Louis, Missouri, USA., Xiong C; Department of Biostatistics, Washington University St. Louis, St. Louis, Missouri, USA., Cruchaga C; Department of Psychiatry, Washington University St. Louis, St. Louis, Missouri, USA., Renton AE; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Perrin RJ; Department of Neurology, Washington University St. Louis, St. Louis, Missouri, USA.; Department of Pathology and Immunology, Washington University St. Louis, St. Louis, Missouri, USA., Berman SB; Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Chhatwal JP; Department of Neurology, Massachusetts General and Brigham & Female's Hospitals, Harvard Medical School, Boston, Massachusetts, USA., Farlow MR; Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Day GS; Department of Neurology, Mayo Clinic Florida, Jacksonville, Florida, USA., Ikeuchi T; Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan., Jucker M; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Lopera F; Grupo de Neurociencias de Antioquia (GNA), Universidad de Antioquia, Medellin, Colombia., Mori H; Department of Clinical Neuroscience, Osaka Metropolitan University Medical School, Nagaoka Sutoku University, Osaka, Japan., Noble JM; Department of Neurology, Columbia University Irving Medical Center, New York, New York, USA., Sánchez-Valle R; Department of Neurology, Hospital Clínic de Barcelona (IDIBAPS), University of Barcelona, Barcelona, Spain., Schofield PR; Neuroscience Research Australia, Sydney, New South Wales, Australia.; School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia., Morris JC; Department of Neurology, Washington University St. Louis, St. Louis, Missouri, USA., Daniels A; Department of Neurology, Washington University St. Louis, St. Louis, Missouri, USA., Levin J; Department of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Bateman RJ; Department of Neurology, Washington University St. Louis, St. Louis, Missouri, USA., McDade E; Department of Neurology, Washington University St. Louis, St. Louis, Missouri, USA., Llibre-Guerra JJ; Department of Neurology, Washington University St. Louis, St. Louis, Missouri, USA.

مؤلفون مشاركون: Dominantly Inherited Alzheimer Network

المصدر: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Jan; Vol. 20 (1), pp. 47-62. Date of Electronic Publication: 2023 Sep 23.

نوع المنشور: Observational Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/diagnostic imaging , Alzheimer Disease*/genetics , Alzheimer Disease*/cerebrospinal fluid, Humans ; Female ; Male ; Amyloid beta-Peptides/cerebrospinal fluid ; Cross-Sectional Studies ; Sex Characteristics ; Positron-Emission Tomography ; Mutation/genetics ; Biomarkers

المؤلفون: McKay NS; Washington University in St. Louis, St. Louis, MO, USA., Gordon BA; Washington University in St. Louis, St. Louis, MO, USA., Hornbeck RC; Washington University in St. Louis, St. Louis, MO, USA., Dincer A; Washington University in St. Louis, St. Louis, MO, USA., Flores S; Washington University in St. Louis, St. Louis, MO, USA., Keefe SJ; Washington University in St. Louis, St. Louis, MO, USA., Joseph-Mathurin N; Washington University in St. Louis, St. Louis, MO, USA., Jack CR; Mayo Clinic, Rochester, MN, USA., Koeppe R; University of Michigan, Ann Arbor, MI, USA., Millar PR; Washington University in St. Louis, St. Louis, MO, USA., Ances BM; Washington University in St. Louis, St. Louis, MO, USA., Chen CD; Washington University in St. Louis, St. Louis, MO, USA., Daniels A; Washington University in St. Louis, St. Louis, MO, USA., Hobbs DA; Washington University in St. Louis, St. Louis, MO, USA., Jackson K; Washington University in St. Louis, St. Louis, MO, USA., Koudelis D; Washington University in St. Louis, St. Louis, MO, USA., Massoumzadeh P; Washington University in St. Louis, St. Louis, MO, USA., McCullough A; Washington University in St. Louis, St. Louis, MO, USA., Nickels ML; Washington University in St. Louis, St. Louis, MO, USA., Rahmani F; Washington University in St. Louis, St. Louis, MO, USA., Swisher L; Washington University in St. Louis, St. Louis, MO, USA., Wang Q; Washington University in St. Louis, St. Louis, MO, USA., Allegri RF; Institute of Neurological Research Fleni, Buenos Aires, Argentina., Berman SB; University of Pittsburgh, Pittsburgh, PA, USA., Brickman AM; Columbia University Irving Medical Center, New York, NY, USA., Brooks WS; Neuroscience Research Australia, Sydney, New South Wales, Australia., Cash DM; UK Dementia Research Institute at University College London, London, UK.; University College London, London, UK., Chhatwal JP; Massachusetts General and Brigham & Women's Hospitals, Harvard Medical School, Boston, MA, USA., Day GS; Mayo Clinic, Jacksonville, FL, USA., Farlow MR; Indiana University School of Medicine, Bloomington, IN, USA., la Fougère C; Department of Radiology, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Fox NC; UK Dementia Research Institute at University College London, London, UK.; University College London, London, UK., Fulham M; Royal Prince Alfred Hospital, Sydney, New South Wales, Australia., Ghetti B; Indiana University School of Medicine, Bloomington, IN, USA., Graff-Radford N; Mayo Clinic, Jacksonville, FL, USA., Ikeuchi T; Niigata University, Niigata, Japan., Klunk W; University of Pittsburgh, Pittsburgh, PA, USA., Lee JH; Asan Medical Center, Seoul, South Korea., Levin J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Martins R; Edith Cowan University, Joondalup, Western Australia, Australia., Masters CL; University of Melbourne, Melbourne, Victoria, Australia., McConathy J; University of Alabama at Birmingham, Birmingham, AL, USA., Mori H; Osaka City University, Osaka, Japan., Noble JM; Columbia University Irving Medical Center, New York, NY, USA., Reischl G; Department of Radiology, University of Tübingen, Tübingen, Germany., Rowe C; University of Melbourne, Melbourne, Victoria, Australia., Salloway S; Brown University. Butler Hospital, Providence, RI, USA., Sanchez-Valle R; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain., Schofield PR; Neuroscience Research Australia, Sydney, New South Wales, Australia.; School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia., Shimada H; Osaka City University, Osaka, Japan., Shoji M; Hirosaki University, Hirosaki, Japan., Su Y; Banner Alzheimer's Institute, Phoenix, AZ, USA., Suzuki K; University of Tokyo, Tokyo, Japan., Vöglein J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Department of Neurology, Ludwig-Maximilians-Universität München, München, Germany., Yakushev I; School of Medicine, Technical University of Munich, Munich, Germany., Cruchaga C; Washington University in St. Louis, St. Louis, MO, USA., Hassenstab J; Washington University in St. Louis, St. Louis, MO, USA., Karch C; Washington University in St. Louis, St. Louis, MO, USA., McDade E; Washington University in St. Louis, St. Louis, MO, USA., Perrin RJ; Washington University in St. Louis, St. Louis, MO, USA., Xiong C; Washington University in St. Louis, St. Louis, MO, USA., Morris JC; Washington University in St. Louis, St. Louis, MO, USA., Bateman RJ; Washington University in St. Louis, St. Louis, MO, USA., Benzinger TLS; Washington University in St. Louis, St. Louis, MO, USA. benzingert@wustl.edu.

مؤلفون مشاركون: Dominantly Inherited Alzheimer Network

المصدر: Nature neuroscience [Nat Neurosci] 2023 Aug; Vol. 26 (8), pp. 1449-1460. Date of Electronic Publication: 2023 Jul 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/diagnostic imaging , Alzheimer Disease*/genetics , Arthrogryposis*, Humans ; Positron-Emission Tomography ; Magnetic Resonance Imaging ; Neuroimaging ; Mutation/genetics ; Amyloid beta-Peptides/genetics

المؤلفون: Chen CD; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA.; Washington University School of Medicine, 660 South Euclid, Campus Box 8225, St. Louis, MO, 63110, USA., McCullough A; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Gordon B; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Joseph-Mathurin N; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Flores S; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., McKay NS; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Hobbs DA; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Hornbeck R; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Fagan AM; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Cruchaga C; Department of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA., Goate AM; Department of Genetics and Genomic Sciences, Ichan School of Medicine at Mount Sinai, New York, NY, USA., Perrin RJ; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA., Wang G; Department of Biostatistics, Washington University in St. Louis, St. Louis, MO, USA., Li Y; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Shi X; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Xiong C; Department of Biostatistics, Washington University in St. Louis, St. Louis, MO, USA., Pontecorvo MJ; Avid Radiopharmaceuticals, Philadelphia, PA, USA.; Eli Lilly and Company, Indianapolis, IN, USA., Klein G; F. Hoffmann-La Roche Ltd., Basel, Switzerland., Su Y; Banner Alzheimer's Institute, Banner Health, Phoenix, AZ, USA.; Arizona Alzheimer's Consortium, Phoenix, AZ, USA., Klunk WE; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Jack C; Department of Radiology, Mayo Clinic, Rochester, MN, USA., Koeppe R; Department of Radiology, University of Michigan, Ann Arbor, MI, USA., Snider BJ; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Berman SB; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., Roberson ED; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Brosch J; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA., Surti G; Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA., Jiménez-Velázquez IZ; Department of Medicine, University of Puerto Rico School of Medicine, San Juan, PR, USA., Galasko D; Department of Neurology, University of California San Diego, San Diego, CA, USA., Honig LS; Department of Neurology, Columbia University, New York, NY, USA., Brooks WS; Prince of Wales Medical Research Institute, University of New South Wales, Sydney, NSW, Australia., Clarnette R; Department of Internal Medicine, University of Western Australia, Crawley, WA, Australia., Wallon D; Department of Neurology and CNR-MAJ, Normandie Univ, UNIROUEN, INSERM U1245, CHU Rouen, F-76000, Rouen, France., Dubois B; Sorbonne Université, AP-HP, GRC No. 21, APM, Hôpital de La Pitié-Salpêtrière, Paris, France.; Institut du Cerveau Et de La Moelle Épinière, INSERM U1127, CNRS UMR 7225, Paris, France.; Institut de La Mémoire Et de La Maladie d'Alzheimer, Département de Neurologie, Hôpital de La Pitié-Salpêtrière, Paris, France., Pariente J; Department of Neurology, Hôpital Pierre-Paul Riquet, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.; Toulouse NeuroImaging Centre, Université de Toulouse, INSERM, UPS, Toulouse, France., Pasquier F; Univ. Lille, INSERM, CHU Lille, 59000, Lille, France.; CNR-MAJ, Labex DISTALZ, LiCEND, 59000, Lille, France., Sanchez-Valle R; Alzheimer's Disease and Other Cognitive Disorders Unit, Hospital ClínicInstitut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Fundació Clínic Per a La Recerca Biomèdica, University of Barcelona, Barcelona, Spain., Shcherbinin S; Eli Lilly and Company, Indianapolis, IN, USA., Higgins I; Eli Lilly and Company, Indianapolis, IN, USA., Tunali I; Eli Lilly and Company, Indianapolis, IN, USA., Masters CL; The Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia., van Dyck CH; Yale School of Medicine, New Haven, CT, USA., Masellis M; Sunnybrook Research Institute, Toronto, ON, Canada., Hsiung R; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada., Gauthier S; Douglas Mental Health University Institute, Montreal, QC, Canada., Salloway S; Alpert Medical School of Brown University, Providence, RI, USA., Clifford DB; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Mills S; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Supnet-Bell C; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., McDade E; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Bateman RJ; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Benzinger TLS; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA. benzingert@wustl.edu.

مؤلفون مشاركون: DIAN-TU Study Team

المصدر: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2023 Jul; Vol. 50 (9), pp. 2669-2682. Date of Electronic Publication: 2023 Apr 05.

نوع المنشور: Clinical Trial, Phase III; Clinical Trial, Phase II; Journal Article

بيانات الدورية: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/diagnostic imaging , Alzheimer Disease*/drug therapy, Humans ; Amyloid beta-Peptides/metabolism ; Positron-Emission Tomography/methods ; Aniline Compounds ; Ethylene Glycols ; Brain/metabolism

المؤلفون: Flores S; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., Chen CD; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., Su Y; Banner Alzheimer's Institute, Phoenix, Arizona., Dincer A; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., Keefe SJ; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., McKay NS; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., Paulick AM; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., Perez-Carrillo GG; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., Wang L; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., Hornbeck RC; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., Goyal M; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri.; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri.; Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Missouri; and., Vlassenko A; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri.; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri., Schwarz S; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., Nickels ML; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., Wong DF; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., Tu Z; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri., McConathy JE; University of Alabama at Birmingham, Birmingham, Alabama., Morris JC; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri.; Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Missouri; and., Benzinger TLS; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri.; Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Missouri; and., Gordon BA; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri; bagordon@wustl.edu.; Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Missouri; and.

المصدر: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2023 Feb; Vol. 64 (2), pp. 287-293. Date of Electronic Publication: 2022 Aug 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/metabolism , Cognitive Dysfunction*/metabolism, Humans ; Female ; Male ; Brain/metabolism ; Positron-Emission Tomography ; Skull/diagnostic imaging ; Skull/metabolism ; Amyloid beta-Peptides/metabolism ; Amyloid/metabolism ; tau Proteins/metabolism ; Carbolines/metabolism

المؤلفون: Dincer A; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Chen CD; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., McKay NS; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Koenig LN; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., McCullough A; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Flores S; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Keefe SJ; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Schultz SA; Massachusetts General Hospital, Boston, MA 02114, USA., Feldman RL; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Joseph-Mathurin N; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Hornbeck RC; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Cruchaga C; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO 63110, USA., Schindler SE; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Holtzman DM; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, Saint Louis, MO 63110, USA., Morris JC; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Fagan AM; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Benzinger TLS; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Gordon BA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Psychological and Brain Sciences, Washington University, Saint Louis, MO 63110, USA.

المصدر: Science translational medicine [Sci Transl Med] 2022 Nov 16; Vol. 14 (671), pp. eabl7646. Date of Electronic Publication: 2022 Nov 16.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Apolipoprotein E4*/genetics , Alzheimer Disease*/pathology, Female ; Humans ; tau Proteins/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Amyloid beta-Peptides/metabolism ; Apolipoproteins E/genetics ; Genotype ; Positron-Emission Tomography ; Brain/metabolism