المؤلفون: Meadows AM; Laboratory of Mitochondrial Biology and Metabolism, NHLBI, NIH, Bethesda, MD, USA.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK., Han K; Laboratory of Mitochondrial Biology and Metabolism, NHLBI, NIH, Bethesda, MD, USA., Singh K; Laboratory of Mitochondrial Biology and Metabolism, NHLBI, NIH, Bethesda, MD, USA., Murgia A; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK., McNally BD; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK., West JA; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK., Huffstutler RD; Cardiovascular Branch, NHLBI, NIH, Bethesda, MD, USA., Powell-Wiley TM; Social Determinants of Obesity and Cardiovascular Risk Laboratory, NHLBI, NIH, Bethesda, MD, USA., Baumer Y; Social Determinants of Obesity and Cardiovascular Risk Laboratory, NHLBI, NIH, Bethesda, MD, USA., Griffin JL; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK.; The Rowett Institute, School of Medicine, Medical Sciences and Nutrition, Foresterhill Campus, Aberdeen, UK., Sack MN; Laboratory of Mitochondrial Biology and Metabolism, NHLBI, NIH, Bethesda, MD, USA.; Cardiovascular Branch, NHLBI, NIH, Bethesda, MD, USA.

المصدر: IScience [iScience] 2023 Apr 06; Vol. 26 (5), pp. 106578. Date of Electronic Publication: 2023 Apr 06 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

المؤلفون: McNally BD; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., Ashley DF; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., Hänschke L; Life & Medical Sciences Institute (LIMES) Development, Genetics & Molecular Physiology Unit, University of Bonn, Carl-Troll-Straße, 31, 53115, Bonn, Germany., Daou HN; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK., Watt NT; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK., Murfitt SA; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., MacCannell ADV; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK., Whitehead A; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK., Bowen TS; Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Sanders FWB; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., Vacca M; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK.; Clinica Medica 'Frugoni', Interdisciplinar Department of Medicine, University of Bari 'Aldo Moro', Bari, Italy., Witte KK; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK., Davies GR; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Bauer R; Life & Medical Sciences Institute (LIMES) Development, Genetics & Molecular Physiology Unit, University of Bonn, Carl-Troll-Straße, 31, 53115, Bonn, Germany., Griffin JL; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Roberts LD; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK. L.D.Roberts@leeds.ac.uk.

المصدر: Nature communications [Nat Commun] 2022 Apr 01; Vol. 13 (1), pp. 1748. Date of Electronic Publication: 2022 Apr 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Ceramides*/metabolism , Endoplasmic Reticulum Stress*/physiology, Animals ; Endoplasmic Reticulum/metabolism ; Mice ; Muscle, Skeletal/metabolism ; Unfolded Protein Response

المؤلفون: O'Brien KA; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3EG, UK. ko337@cam.ac.uk., McNally BD; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Sanger Building Tennis Court Road, Cambridge, CB2 1GA, UK., Sowton AP; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3EG, UK., Murgia A; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Sanger Building Tennis Court Road, Cambridge, CB2 1GA, UK., Armitage J; Global Investigative Safety, GlaxoSmithKline R&D, Park Road, Ware, Hertfordshire, SG12 0DP, UK., Thomas LW; Department of Medicine, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK., Krause FN; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Sanger Building Tennis Court Road, Cambridge, CB2 1GA, UK., Maddalena LA; Department of Medicine, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK., Francis I; Ultrastructure and Cellular Bioimaging, GlaxoSmithKline R&D, Park Road, Ware, Hertfordshire, SG12 0DP, UK., Kavanagh S; Oncology Safety Sciences, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, CB2 OAA, Cambridge, UK., Williams DP; Functional and Mechanistic Safety, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, CB2 OAA, Cambridge, UK., Ashcroft M; Department of Medicine, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK., Griffin JL; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Sanger Building Tennis Court Road, Cambridge, CB2 1GA, UK.; Section of Biomolecular Medicine, Department of Digestion, Metabolism and Reproduction, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK., Lyon JJ; Global Investigative Safety, GlaxoSmithKline R&D, Park Road, Ware, Hertfordshire, SG12 0DP, UK., Murray AJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3EG, UK. ajm267@cam.ac.uk.

المصدر: BMC biology [BMC Biol] 2021 Dec 15; Vol. 19 (1), pp. 265. Date of Electronic Publication: 2021 Dec 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007 (Electronic) Linking ISSN: 17417007 NLM ISO Abbreviation: BMC Biol Subsets: MEDLINE

مواضيع طبية MeSH: Lipid Metabolism* , Liver*/metabolism, Homeostasis ; Humans ; Hypoxia/metabolism ; Lipogenesis

المؤلفون: McKenna HT; Division of Surgery and Interventional Science, University College London, Royal Free Hospital, London, NW3 2QG, UK; Intensive Care Unit, Royal Free Hospital, London, NW3 2QG, UK; Peninsula Medical School, University of Plymouth, John Bull Building, Derriford, Plymouth, PL6 8BU, UK., O'Brien KA; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK., Fernandez BO; Clinical & Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, SO16 6YD, UK., Minnion M; Clinical & Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, SO16 6YD, UK., Tod A; Clinical & Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, SO16 6YD, UK., McNally BD; Department of Biochemistry and the Cambridge Systems Biology Centre, University of Cambridge, CB2 1GA, UK., West JA; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Department of Medicine, Jeffrey Cheah Biomedical Centre, University of Cambridge, CB2 0RE, UK., Griffin JL; Department of Biochemistry and the Cambridge Systems Biology Centre, University of Cambridge, CB2 1GA, UK; Section of Biomolecular Medicine, Department of Digestion, Metabolism and Reproduction, Imperial College London, SW7 2AZ, UK., Grocott MP; Anaesthesia Perioperative and Critical Care Research Group, Southampton National Institute of Health Research Biomedical Research Centre, University Hospital Southampton, SO16 6YD, UK., Mythen MG; University College London Hospitals and Great Ormond Street, National Institute of Health Research Biomedical Research Centres, London, WC1N 1EH, UK., Feelisch M; Clinical & Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, SO16 6YD, UK; Anaesthesia Perioperative and Critical Care Research Group, Southampton National Institute of Health Research Biomedical Research Centre, University Hospital Southampton, SO16 6YD, UK., Murray AJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK. Electronic address: ajm267@cam.ac.uk., Martin DS; Division of Surgery and Interventional Science, University College London, Royal Free Hospital, London, NW3 2QG, UK; Intensive Care Unit, Royal Free Hospital, London, NW3 2QG, UK; Peninsula Medical School, University of Plymouth, John Bull Building, Derriford, Plymouth, PL6 8BU, UK.

المصدر: Redox biology [Redox Biol] 2021 May; Vol. 41, pp. 101907. Date of Electronic Publication: 2021 Feb 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE

مواضيع طبية MeSH: Critical Illness* , Energy Metabolism*, Humans ; Mitochondria/metabolism ; Oxidation-Reduction ; Oxidative Stress ; Survivors

المؤلفون: Whitehead A; School of Medicine, University of Leeds, Leeds, UK., Krause FN; Department of Biochemistry, University of Cambridge, Cambridge, UK., Moran A; School of Medicine, University of Leeds, Leeds, UK., MacCannell ADV; School of Medicine, University of Leeds, Leeds, UK., Scragg JL; School of Medicine, University of Leeds, Leeds, UK., McNally BD; Department of Biochemistry, University of Cambridge, Cambridge, UK., Boateng E; School of Medicine, University of Leeds, Leeds, UK., Murfitt SA; Department of Biochemistry, University of Cambridge, Cambridge, UK., Virtue S; Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Wright J; School of Medicine, University of Leeds, Leeds, UK., Garnham J; School of Medicine, University of Leeds, Leeds, UK., Davies GR; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Dodgson J; Phenotypic Screening and High Content Imaging, Antibody Discovery & Protein Engineering, R&D, AstraZeneca, Cambridge, UK., Schneider JE; School of Medicine, University of Leeds, Leeds, UK., Murray AJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Church C; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Vidal-Puig A; Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Witte KK; School of Medicine, University of Leeds, Leeds, UK., Griffin JL; Department of Biochemistry, University of Cambridge, Cambridge, UK., Roberts LD; School of Medicine, University of Leeds, Leeds, UK. L.D.Roberts@leeds.ac.uk.

المصدر: Nature communications [Nat Commun] 2021 Mar 26; Vol. 12 (1), pp. 1905. Date of Electronic Publication: 2021 Mar 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Adipose Tissue, Beige/*metabolism , Adipose Tissue, Brown/*metabolism , Energy Metabolism/*genetics , Homeostasis/*genetics , Signal Transduction/*genetics, Adipocytes, Brown/metabolism ; Adipocytes, White/metabolism ; Adipose Tissue, Beige/cytology ; Adipose Tissue, Brown/cytology ; Animals ; Cell Line ; Cells, Cultured ; Chromatography, Liquid ; Gas Chromatography-Mass Spectrometry ; Gene Expression Profiling/methods ; Humans ; Male ; Mass Spectrometry ; Metabolomics/methods ; Mice, Inbred C57BL ; Mice

المؤلفون: Lecommandeur E; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK., Cachón-González MB; Department of Medicine, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Boddie S; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK., McNally BD; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK., Nicholls AW; GlaxoSmithKline, Stevenage SG1 2NY, UK., Cox TM; Department of Medicine, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Griffin JL; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK.; Hammersmith Campus, UK Dementia Research Institute at Imperial College, Burlington Danes Building, Imperial College London, Du Cane Road, London W12 0NN, UK.; Section of Biomolecular Medicine, Department of Metabolism, Division of Systems Medicine, Digestion and Reproduction, The Sir Alexander Fleming Building, Exhibition Road, South Kensington, Imperial College London, London SW7 2AZ, UK.

المصدر: Metabolites [Metabolites] 2020 Dec 30; Vol. 11 (1). Date of Electronic Publication: 2020 Dec 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101578790 Publication Model: Electronic Cited Medium: Print ISSN: 2218-1989 (Print) Linking ISSN: 22181989 NLM ISO Abbreviation: Metabolites Subsets: PubMed not MEDLINE

المؤلفون: McNally BD; Medical Research Council - Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, U.K.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K., Moran A; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, U.K., Watt NT; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, U.K., Ashmore T; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, U.K., Whitehead A; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, U.K., Murfitt SA; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K., Kearney MT; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, U.K., Cubbon RM; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, U.K., Murray AJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, U.K., Griffin JL; Medical Research Council - Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, U.K.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, U.K., Roberts LD; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, U.K. l.d.roberts@leeds.ac.uk.

المصدر: Diabetes [Diabetes] 2020 May; Vol. 69 (5), pp. 893-901. Date of Electronic Publication: 2020 Feb 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

مواضيع طبية MeSH: Adipose Tissue, White/*drug effects , Adipose Tissue, White/*metabolism , Glucose/*metabolism , Nitrates/*pharmacology , Nitric Oxide/*metabolism , Xanthine Dehydrogenase/*metabolism, Adipocytes/drug effects ; Adipocytes/metabolism ; Animals ; Cells, Cultured ; Gene Expression Regulation, Enzymologic/drug effects ; Gene Expression Regulation, Enzymologic/physiology ; Male ; Metabolism ; Nitrates/administration & dosage ; Oxidation-Reduction ; Rats ; Rats, Wistar

المؤلفون: Sowton AP; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK.; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., Padmanabhan N; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK.; Centre for Trophoblast Research, University of Cambridge, Cambridge, CB2 3EG, UK., Tunster SJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK.; Centre for Trophoblast Research, University of Cambridge, Cambridge, CB2 3EG, UK., McNally BD; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., Murgia A; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., Yusuf A; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK., Griffin JL; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK.; Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, SW7 2AZ, UK., Murray AJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK.; Centre for Trophoblast Research, University of Cambridge, Cambridge, CB2 3EG, UK., Watson ED; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK.; Centre for Trophoblast Research, University of Cambridge, Cambridge, CB2 3EG, UK.

المصدر: Molecular genetics and metabolism reports [Mol Genet Metab Rep] 2020 Mar 24; Vol. 23, pp. 100580. Date of Electronic Publication: 2020 Mar 24 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101624422 Publication Model: eCollection Cited Medium: Print ISSN: 2214-4269 (Print) Linking ISSN: 22144269 NLM ISO Abbreviation: Mol Genet Metab Rep Subsets: PubMed not MEDLINE

المؤلفون: Charidemou E; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, United Kingdom., Ashmore T; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, United Kingdom., Li X; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, United Kingdom., McNally BD; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, United Kingdom., West JA; Division of Gastroenterology and Hepatology, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Liggi S; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, United Kingdom., Harvey M; Medical Research Council - Elsie Widdowson Laboratory, Cambridge, United Kingdom., Orford E; Medical Research Council - Elsie Widdowson Laboratory, Cambridge, United Kingdom., Griffin JL; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, United Kingdom.; Computational and Systems Medicine, Surgery and Cancer, Imperial College London, London, United Kingdom.

المصدر: JCI insight [JCI Insight] 2019 May 30; Vol. 4 (12). Date of Electronic Publication: 2019 May 30 (Print Publication: 2019).

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Lipogenesis*, Diet, High-Protein/*adverse effects , Feeding Behavior/*physiology , Liver/*metabolism , Triglycerides/*biosynthesis, Administration, Oral ; Adult ; Amino Acids/administration & dosage ; Amino Acids/adverse effects ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/prevention & control ; Dietary Proteins/administration & dosage ; Dietary Proteins/adverse effects ; Healthy Volunteers ; Hepatocytes/metabolism ; Humans ; Insulin/metabolism ; Insulin Resistance/physiology ; Liver/cytology ; Male ; Non-alcoholic Fatty Liver Disease/metabolism ; Non-alcoholic Fatty Liver Disease/prevention & control ; Obesity/etiology ; Obesity/metabolism ; Triglycerides/blood ; Young Adult

المؤلفون: Roberts LD; Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, U.K. l.d.roberts@leeds.ac.uk.; Medical Research Council-Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, U.K.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K., Ashmore T; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, U.K., McNally BD; Medical Research Council-Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, U.K.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K., Murfitt SA; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K., Fernandez BO; Faculty of Medicine, Clinical and Experimental Sciences, University of Southampton, Southampton General Hospital, Southampton, U.K., Feelisch M; Faculty of Medicine, Clinical and Experimental Sciences, University of Southampton, Southampton General Hospital, Southampton, U.K., Lindsay R; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, U.K., Siervo M; Human Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, U.K., Williams EA; Human Nutrition Unit, Department of Oncology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, U.K., Murray AJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, U.K., Griffin JL; Medical Research Council-Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, U.K.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K.

المصدر: Diabetes [Diabetes] 2017 Mar; Vol. 66 (3), pp. 674-688. Date of Electronic Publication: 2016 Dec 27.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

مواضيع طبية MeSH: Physical Conditioning, Animal*, Fibronectins/*drug effects , Muscle Fibers, Skeletal/*drug effects , Nitrates/*pharmacology , Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/*drug effects, Adipocytes/drug effects ; Adipocytes/metabolism ; Aged ; Aminoisobutyric Acids ; Animals ; Beta vulgaris ; Chromatography, Liquid ; Double-Blind Method ; Female ; Fibronectins/metabolism ; Fruit and Vegetable Juices ; Gas Chromatography-Mass Spectrometry ; Growth Hormone/metabolism ; Humans ; Immunohistochemistry ; In Vitro Techniques ; Insulin Resistance ; Male ; Mass Spectrometry ; Mice ; Mice, Transgenic ; Middle Aged ; Muscle Fibers, Fast-Twitch/drug effects ; Muscle Fibers, Fast-Twitch/metabolism ; Muscle Fibers, Skeletal/metabolism ; Muscle Fibers, Slow-Twitch/drug effects ; Muscle Fibers, Slow-Twitch/metabolism ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/metabolism ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/genetics ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Rats ; Rats, Wistar ; Transcriptome ; gamma-Aminobutyric Acid/drug effects ; gamma-Aminobutyric Acid/metabolism