المؤلفون: Cundy NJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Arciszewski J; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Gates EWJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Acton SL; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Passley KD; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Awoonor-Williams E; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Boyd EK; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Xu N; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Pierson É; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Fernandez-Ansieta C; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Albert MR; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., McNeil NMR; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Adhikary G; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine Baltimore Maryland 21201 USA., Eckert RL; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine Baltimore Maryland 21201 USA., Keillor JW; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca.

المصدر: RSC medicinal chemistry [RSC Med Chem] 2022 Dec 28; Vol. 14 (2), pp. 378-385. Date of Electronic Publication: 2022 Dec 28 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101759460 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8682 (Electronic) Linking ISSN: 26328682 NLM ISO Abbreviation: RSC Med Chem Subsets: PubMed not MEDLINE

المؤلفون: McNeil NMR; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada., Gates EWJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada., Firoozi N; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada., Cundy NJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada., Leccese J; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada., Eisinga S; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada., Tyndall JDA; School of Pharmacy, University of Otago, Dunedin, 9054, New Zealand., Adhikary G; Department of Biochemistry and Molecular Biology, and the Greenebaum Comprehensive Cancer Center, The University of Maryland School of Medicine, Baltimore, MD, 21021, USA., Eckert RL; Department of Biochemistry and Molecular Biology, and the Greenebaum Comprehensive Cancer Center, The University of Maryland School of Medicine, Baltimore, MD, 21021, USA., Keillor JW; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada. Electronic address: jkeillor@uottawa.ca.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2022 Mar 15; Vol. 232, pp. 114172. Date of Electronic Publication: 2022 Feb 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Peptidomimetics*/pharmacology , Transglutaminases*/chemistry , Transglutaminases*/genetics , Transglutaminases*/metabolism, Enzyme Inhibitors/chemistry ; Protein Glutamine gamma Glutamyltransferase 2 ; Structure-Activity Relationship

المؤلفون: Akbar A; Department of Chemistry and Biomolecular Sciences, University of Ottawa , 10 Marie-Curie, Ottawa, Ontario K1N 6N5, Canada., McNeil NMR; Department of Chemistry and Biomolecular Sciences, University of Ottawa , 10 Marie-Curie, Ottawa, Ontario K1N 6N5, Canada., Albert MR; Department of Chemistry and Biomolecular Sciences, University of Ottawa , 10 Marie-Curie, Ottawa, Ontario K1N 6N5, Canada., Ta V; Department of Chemistry and Biomolecular Sciences, University of Ottawa , 10 Marie-Curie, Ottawa, Ontario K1N 6N5, Canada., Adhikary G; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine , Baltimore, Maryland 21201, United States., Bourgeois K; Department of Chemistry and Biomolecular Sciences, University of Ottawa , 10 Marie-Curie, Ottawa, Ontario K1N 6N5, Canada., Eckert RL; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine , Baltimore, Maryland 21201, United States., Keillor JW; Department of Chemistry and Biomolecular Sciences, University of Ottawa , 10 Marie-Curie, Ottawa, Ontario K1N 6N5, Canada.

المصدر: Journal of medicinal chemistry [J Med Chem] 2017 Sep 28; Vol. 60 (18), pp. 7910-7927. Date of Electronic Publication: 2017 Sep 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Enzyme Inhibitors/*chemistry , Enzyme Inhibitors/*pharmacology , GTP-Binding Proteins/*antagonists & inhibitors , Guanosine Triphosphate/*metabolism , Transglutaminases/*antagonists & inhibitors, Cell Line ; GTP-Binding Proteins/metabolism ; Humans ; Neoplastic Stem Cells/cytology ; Neoplastic Stem Cells/drug effects ; Neoplastic Stem Cells/metabolism ; Protein Binding/drug effects ; Protein Glutamine gamma Glutamyltransferase 2 ; Structure-Activity Relationship ; Transglutaminases/metabolism