المؤلفون: Vogel-Scibilia SE, McNulty KC, Baxter B, Miller S, Dine M, Frese FJ III

المصدر: Community Mental Health Journal; Dec2009, Vol. 45 Issue 6, p405-414, 10p

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: Mohammad HP; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Smitheman KN; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Kamat CD; Oncology Department, Johns Hopkins University, Baltimore, MD 21231, USA., Soong D; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Federowicz KE; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Van Aller GS; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Schneck JL; Platform Technology and Sciences, GlaxoSmithKline, Collegeville, PA 19426, USA., Carson JD; Platform Technology and Sciences, GlaxoSmithKline, Collegeville, PA 19426, USA., Liu Y; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Butticello M; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Bonnette WG; Platform Technology and Sciences, GlaxoSmithKline, Collegeville, PA 19426, USA., Gorman SA; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Degenhardt Y; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Bai Y; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., McCabe MT; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Pappalardi MB; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Kasparec J; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Tian X; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., McNulty KC; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Rouse M; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., McDevitt P; Platform Technology and Sciences, GlaxoSmithKline, Collegeville, PA 19426, USA., Ho T; Platform Technology and Sciences, GlaxoSmithKline, Collegeville, PA 19426, USA., Crouthamel M; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Hart TK; Safety Assessment Department, GlaxoSmithKline, Upper Merion, PA 19406, USA., Concha NO; Platform Technology and Sciences, GlaxoSmithKline, Collegeville, PA 19426, USA., McHugh CF; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Miller WH; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Dhanak D; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Tummino PJ; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Carpenter CL; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Johnson NW; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA., Hann CL; Oncology Department, Johns Hopkins University, Baltimore, MD 21231, USA., Kruger RG; Cancer Epigenetics Department, GlaxoSmithKline, Collegeville, PA 19426, USA. Electronic address: ryan.g.kruger@gsk.com.

المصدر: Cancer cell [Cancer Cell] 2015 Jul 13; Vol. 28 (1), pp. 57-69.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*administration & dosage , Benzoates/*administration & dosage , Cyclopropanes/*administration & dosage , DNA Methylation/*drug effects , Enzyme Inhibitors/*administration & dosage , Histone Demethylases/*antagonists & inhibitors , Lung Neoplasms/*drug therapy , Small Cell Lung Carcinoma/*drug therapy, Administration, Oral ; Animals ; Antineoplastic Agents/pharmacology ; Benzoates/pharmacology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cyclopropanes/pharmacology ; Enzyme Inhibitors/pharmacology ; Epigenesis, Genetic/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Histone Demethylases/genetics ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Mice ; Molecular Sequence Data ; Small Cell Lung Carcinoma/genetics ; Small Cell Lung Carcinoma/pathology ; Xenograft Model Antitumor Assays

المؤلفون: Seefeld MA; Oncology Chemistry, GlaxoSmithKline, Collegeville, PA 19426, USA., Rouse MB, McNulty KC, Sun L, Wang J, Yamashita DS, Luengo JI, Zhang S, Minthorn EA, Concha NO, Heerding DA

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Apr 15; Vol. 19 (8), pp. 2244-8. Date of Electronic Publication: 2009 Feb 27.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery*/methods, Protein Kinase Inhibitors/*chemical synthesis , Proto-Oncogene Proteins c-akt/*antagonists & inhibitors , Pyridines/*chemical synthesis , Pyridines/*pharmacology , Thiophenes/*chemistry, Animals ; Crystallography, X-Ray ; Humans ; Mice ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Thienopyridines ; Thiophenes/chemical synthesis ; Thiophenes/pharmacology

المؤلفون: Rouse MB; Oncology Chemistry, GlaxoSmithKline, Collegeville, PA 19426, USA., Seefeld MA, Leber JD, McNulty KC, Sun L, Miller WH, Zhang S, Minthorn EA, Concha NO, Choudhry AE, Schaber MD, Heerding DA

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Mar 01; Vol. 19 (5), pp. 1508-11. Date of Electronic Publication: 2009 Jan 09.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Oxadiazoles/*chemical synthesis , Protein Kinase Inhibitors/*chemical synthesis , Proto-Oncogene Proteins c-akt/*antagonists & inhibitors, Animals ; Cell Line ; Cell Line, Tumor ; Crystallography, X-Ray ; Humans ; Oxadiazoles/chemistry ; Oxadiazoles/pharmacology ; Oxadiazoles/therapeutic use ; Protein Kinase Inhibitors/pharmacology ; Protein Structure, Secondary/physiology ; Proto-Oncogene Proteins c-akt/metabolism ; Structure-Activity Relationship