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المؤلفون: Edelberg JM; Clinical Development, Cardiovascular Global Drug Development, MyoKardia, Inc., A Wholly Owned Subsidiary of Bristol Myers Squibb, Brisbane, CA, USA., Sehnert AJ; Clinical Development, Cardiovascular Global Drug Development, MyoKardia, Inc., A Wholly Owned Subsidiary of Bristol Myers Squibb, Brisbane, CA, USA., Mealiffe ME; Early Clinical Development, MyoKardia, Inc., A Wholly Owned Subsidiary of Bristol Myers Squibb, Brisbane, CA, USA., Del Rio CL; Clinical Development, Cardiovascular Global Drug Development, MyoKardia, Inc., A Wholly Owned Subsidiary of Bristol Myers Squibb, Brisbane, CA, USA., McDowell R; Research & Early Development, MyoKardia, Inc., A Wholly Owned Subsidiary of Bristol Myers Squibb, 1000 Sierra Point Parkway, Brisbane, CA, 94005, USA. rsmcdowell@earthlink.net.

المصدر: American journal of cardiovascular drugs : drugs, devices, and other interventions [Am J Cardiovasc Drugs] 2022 Sep; Vol. 22 (5), pp. 497-510. Date of Electronic Publication: 2022 Apr 18.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 100967755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-187X (Electronic) Linking ISSN: 11753277 NLM ISO Abbreviation: Am J Cardiovasc Drugs Subsets: MEDLINE

مواضيع طبية MeSH: Cardiomyopathy, Hypertrophic*/drug therapy , Cardiomyopathy, Hypertrophic*/metabolism, Benzylamines/metabolism ; Benzylamines/therapeutic use ; Humans ; Sarcomeres/metabolism ; Uracil/analogs & derivatives ; Uracil/metabolism ; Uracil/therapeutic use

المؤلفون: Ho CY; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address: cho@bwh.harvard.edu., Mealiffe ME; MyoKardia, Inc., Brisbane, California., Bach RG; Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri., Bhattacharya M; MyoKardia, Inc., Brisbane, California., Choudhury L; Bluhm Cardiovascular Institute, Northwestern Memorial Hospital, Chicago, Illinois., Edelberg JM; MyoKardia, Inc., Brisbane, California., Hegde SM; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Jacoby D; Department of Internal Medicine, Section of Cardiovascular Diseases, Yale University School of Medicine, New Haven, Connecticut., Lakdawala NK; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Lester SJ; Department of Cardiovascular Diseases, Mayo Clinic Arizona, Phoenix, Arizona., Ma Y; MyoKardia, Inc., Brisbane, California., Marian AJ; Center for Cardiovascular Genetics, Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, Houston, Texas., Nagueh SF; Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital, Houston, Texas., Owens A; Heart and Vascular Center, Perelman Center for Advanced Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Rader F; Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California., Saberi S; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan., Sehnert AJ; MyoKardia, Inc., Brisbane, California., Sherrid MV; Hypertrophic Cardiomyopathy Program, New York University School of Medicine, New York, New York., Solomon SD; Department of Internal Medicine, Section of Cardiovascular Diseases, Yale University School of Medicine, New Haven, Connecticut., Wang A; Duke Cardiology, Duke Health Center at Southpoint, Durham, North Carolina., Wever-Pinzon O; Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah., Wong TC; Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Heitner SB; Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon.

المصدر: Journal of the American College of Cardiology [J Am Coll Cardiol] 2020 Jun 02; Vol. 75 (21), pp. 2649-2660.

نوع المنشور: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Biomedical Country of Publication: United States NLM ID: 8301365 Publication Model: Print Cited Medium: Internet ISSN: 1558-3597 (Electronic) Linking ISSN: 07351097 NLM ISO Abbreviation: J Am Coll Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Benzylamines/*therapeutic use , Cardiomyopathy, Hypertrophic/*drug therapy , Uracil/*analogs & derivatives, Adult ; Aged ; Benzylamines/adverse effects ; Biomarkers/blood ; Cardiomyopathy, Hypertrophic/blood ; Cardiomyopathy, Hypertrophic/diagnostic imaging ; Double-Blind Method ; Echocardiography ; Female ; Humans ; Male ; Middle Aged ; Uracil/adverse effects ; Uracil/therapeutic use

المؤلفون: Mealiffe ME; Perlegen Sciences, Inc, Mountain View, CA, USA., Stokowski RP, Rhees BK, Prentice RL, Pettinger M, Hinds DA

المصدر: Journal of the National Cancer Institute [J Natl Cancer Inst] 2010 Nov 03; Vol. 102 (21), pp. 1618-27. Date of Electronic Publication: 2010 Oct 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 7503089 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2105 (Electronic) Linking ISSN: 00278874 NLM ISO Abbreviation: J Natl Cancer Inst Subsets: MEDLINE

مواضيع طبية MeSH: Models, Statistical* , Polymorphism, Single Nucleotide*, Breast Neoplasms/*diagnosis , Breast Neoplasms/*genetics , White People/*genetics, Age Factors ; Age of Onset ; Aged ; Area Under Curve ; Biomarkers, Tumor/analysis ; Biopsy ; Breast Neoplasms/chemistry ; Case-Control Studies ; Female ; Genetic Predisposition to Disease ; Humans ; Linear Models ; Logistic Models ; Mass Screening ; Menarche ; Middle Aged ; Odds Ratio ; Parturition ; Postmenopause ; Predictive Value of Tests ; ROC Curve ; Receptors, Estrogen/analysis ; Reproducibility of Results ; Risk Assessment ; Risk Factors

المؤلفون: Salipante SJ; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA., Mealiffe ME, Wechsler J, Krem MM, Liu Y, Namkoong S, Bhagat G, Kirchhoff T, Offit K, Lynch H, Wiernik PH, Roshal M, McMaster ML, Tucker M, Fromm JR, Goldin LR, Horwitz MS

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2009 Sep 01; Vol. 106 (35), pp. 14920-5. Date of Electronic Publication: 2009 Aug 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Chromosomes, Human, Pair 2* , Chromosomes, Human, Pair 3* , Mutation*, Antigens, Neoplasm/*genetics , Cell Nucleus/*genetics , Hodgkin Disease/*genetics, 5' Untranslated Regions ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Animals ; Base Sequence ; Female ; Genetic Predisposition to Disease ; Hodgkin Disease/pathology ; Humans ; Male ; Middle Aged ; Pedigree ; Reed-Sternberg Cells/metabolism ; Sequence Alignment ; Sequence Homology, Nucleic Acid ; Young Adult

المؤلفون: Horwitz MS; Division of Medical Genetics, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA. horwitz@u.washington.edu, Duan Z, Korkmaz B, Lee HH, Mealiffe ME, Salipante SJ

المصدر: Blood [Blood] 2007 Mar 01; Vol. 109 (5), pp. 1817-24. Date of Electronic Publication: 2006 Oct 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0006-4971 (Print) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Leukocyte Elastase/*metabolism , Neutropenia/*enzymology , Neutropenia/*pathology, Animals ; Cell Differentiation ; Genotype ; Humans ; Leukocyte Elastase/genetics ; Models, Biological ; Mutation/genetics ; Neutropenia/congenital ; Neutropenia/genetics

المؤلفون: Horwitz MS, Mealiffe ME

المصدر: Leukemia [Leukemia] 2007 Feb; Vol. 21 (2), pp. 351. Date of Electronic Publication: 2006 Dec 07.

نوع المنشور: Comment; Letter; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0887-6924 (Print) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: Databases, Factual/*statistics & numerical data , Hodgkin Disease/*genetics, Family ; Female ; Hodgkin Disease/epidemiology ; Humans ; Male ; Sweden/epidemiology