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1دورية أكاديميةDual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF
المؤلفون: Martin L. Decaris, Johanna R. Schaub, Chun Chen, Jacob Cha, Gail G. Lee, Megi Rexhepaj, Steve S. Ho, Vikram Rao, Megan M. Marlow, Prerna Kotak, Erine H. Budi, Lisa Hooi, Jianfeng Wu, Marina Fridlib, Shamra P. Martin, Shaoyi Huang, Ming Chen, Manuel Muñoz, Timothy F. Hom, Paul J. Wolters, Tushar J. Desai, Fernando Rock, Katerina Leftheris, David J. Morgans, Eve-Irene Lepist, Patrick Andre, Eric A. Lefebvre, Scott M. Turner
المصدر: Respiratory Research, Vol 22, Iss 1, Pp 1-14 (2021)
مصطلحات موضوعية: Transforming growth factor-β, Precision-cut lung slice, Antifibrotic, αv integrin, PLN-74809, Diseases of the respiratory system, RC705-779
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1465-993X
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2دورية أكاديمية
المؤلفون: Fuchao Xu, Russell Butler, Kyle May, Megi Rexhepaj, Dayu Yu, Jiachen Zi, Yi Chen, Yonghong Liang, Jia Zeng, Joan Hevel, Jixun Zhan
المصدر: Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-14 (2019)
مصطلحات موضوعية: Nonribosomal peptide synthetase, Methyltransferase domain, Substrate specificity, Domain removal, Heterologous expression, In vitro reaction, Biology (General), QH301-705.5
وصف الملف: electronic resource
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المؤلفون: Jun Siong Low, Josipa Jerak, M. Alejandra Tortorici, Matthew McCallum, Dora Pinto, Antonino Cassotta, Mathilde Foglierini, Federico Mele, Rana Abdelnabi, Birgit Weynand, Julia Noack, Martin Montiel-Ruiz, Siro Bianchi, Fabio Benigni, Nicole Sprugasci, Anshu Joshi, John E. Bowen, Cameron Stewart, Megi Rexhepaj, Alexandra C. Walls, David Jarrossay, Diego Morone, Philipp Paparoditis, Christian Garzoni, Paolo Ferrari, Alessandro Ceschi, Johan Neyts, Lisa A. Purcell, Gyorgy Snell, Davide Corti, Antonio Lanzavecchia, David Veesler, Federica Sallusto
المساهمون: University of Zurich, Low, Jun Siong, Veesler, David, Sallusto, Federica
المصدر: Science. 377:735-742
مصطلحات موضوعية: 1000 Multidisciplinary, Multidisciplinary, SARS-CoV-2, Antibodies, Monoclonal, COVID-19, 610 Medicine & health, Antibodies, Viral, Antibodies, Neutralizing, 10199 Clinic for Clinical Pharmacology and Toxicology, Spike Glycoprotein, Coronavirus, Animals, Humans, Angiotensin-Converting Enzyme 2, Peptides, Broadly Neutralizing Antibodies, Protein Binding
وصف الملف: Print-Electronic; science.abq2679.pdf - application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b27630ac54e43ea5e98780e8348874
https://doi.org/10.1126/science.abq2679 -
4Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF
المؤلفون: Patrick Andre, Martin Decaris, Chun Chen, Munoz Manuel, Hom Timothy, Scott M. Turner, Ming Chen, Tushar J. Desai, Megan M. Marlow, Cha Jacob, Eric Lefebvre, Steve S. Ho, Paul J. Wolters, Shaoyi Huang, Eve-Irene Lepist, Katerina Leftheris, David J Morgans, Lisa Hooi, Johanna R. Schaub, Vikram R. Rao, Jianfeng Wu, Marina Fridlib, Fernando Rock, Megi Rexhepaj, Erine H. Budi, Prerna Kotak, Gail Lee, Shamra Martin
المصدر: Respiratory research, vol 22, iss 1
Respiratory Research, Vol 22, Iss 1, Pp 1-14 (2021)مصطلحات موضوعية: Precision-cut lung slice, Respiratory System, αv integrin, alpha(v) integrin, Cardiorespiratory Medicine and Haematology, Inbred C57BL, Mice, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, Receptors, Pulmonary fibrosis, Phosphorylation, alpha 1 Chain, Lung, biology, Transforming growth factor-β, Pirfenidone, Transforming growth factor-beta, medicine.anatomical_structure, 5.1 Pharmaceuticals, Respiratory, Nintedanib, Antifibrotic Agents, Development of treatments and therapeutic interventions, Cell activation, Type I collagen, Signal Transduction, medicine.drug, Integrin, Clinical Sciences, Collagen Type I, Cell Line, Diseases of the respiratory system, Bleomycin, Rare Diseases, medicine, Animals, Humans, Vitronectin, Smad3 Protein, PLN-74809, RC705-779, Integrin alpha6beta1, Animal, Epithelial Cells, Fibroblasts, medicine.disease, Coculture Techniques, Idiopathic Pulmonary Fibrosis, chemistry, Disease Models, Cancer research, biology.protein, Antifibrotic
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8943da51a8a3553a1e3711bc9a9ed07
https://escholarship.org/uc/item/5q12m0vq -
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المؤلفون: Eric Lefebvre, Maureen Reilly, Chun Chen, Katerina Leftheris, Vikram R. Rao, Lisa Hooi, Jianfeng Wu, Eduard Gorina, Scott Turner, Gail Lee, Jake Cha, Tony Chen, Johanna R. Schaub, Martin Decaris, Prerna Kotak, Munoz Manuel, Patrick Andre, Hom Timothy, Shamra Martin, Megi Rexhepaj, Cooper Nicole
المصدر: Idiopathic interstitial pneumonias.
مصطلحات موضوعية: biology, Integrin Inhibition, business.industry, Integrin, Pirfenidone, respiratory system, Lung injury, medicine.disease, Bleomycin, respiratory tract diseases, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Fibrosis, biology.protein, Cancer research, Medicine, Nintedanib, business, Fibroblast, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::38c605362d65a6584058ceae0e0ba3df
https://doi.org/10.1183/13993003.congress-2019.pa1286 -
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المؤلفون: Ambro van Hoof, Lindsey K. Lott, Alejandra Klauer King, Lacy L. Taylor, Megi Rexhepaj, Ryan N. Jackson, Sean J. Johnson
المصدر: Nucleic Acids Research
Chemistry and Biochemistry Faculty Publicationsمصطلحات موضوعية: Models, Molecular, Saccharomyces cerevisiae Proteins, Polyadenylation, Ratchet, Biology, Protein Structure, Secondary, DEAD-box RNA Helicases, 03 medical and health sciences, 0302 clinical medicine, Protein structure, RNA unwinding, Genetics, arch domain, 030304 developmental biology, 0303 health sciences, Nucleic Acid Enzymes, Helicase, RNA, RNA Helicase A, Protein Structure, Tertiary, Cell biology, Chemistry, Mtr4 ratchet helix, Mutation, Helix, TRAMP complex, biology.protein, Poly A, 030217 neurology & neurosurgery, Protein Binding
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d4f3c2d2eb4cf93e1ba2dbfc61d4a1
https://doi.org/10.1093/nar/gku1208