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1دورية أكاديمية
المؤلفون: Peter S Kutchukian, Nadya Y Vasilyeva, Jordan Xu, Mika K Lindvall, Michael P Dillon, Meir Glick, John D Coley, Natasja Brooijmans
المصدر: PLoS ONE, Vol 7, Iss 11, p e48476 (2012)
وصف الملف: electronic resource
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المؤلفون: Viktor Pisarenko, Anja Muzdalo, Danny A. Bitton, Petr Mejzlik, Gregory L. Adams, Meir Glick, Kamila Clarova, Esteban Jenkins, Dzianis Hancharyk, Javier L. Baylon, Anna Gromek, Martin Spale, David Bednar, Charlie Chang, Anne Mai Wassermann, Oleg Ursu
المصدر: Journal of chemical information and modeling. 62(5)
مصطلحات موضوعية: chemistry.chemical_classification, Computer science, Drug discovery, General Chemical Engineering, Cheminformatics, Proteins, Peptide, Computational biology, General Chemistry, Library and Information Sciences, chEMBL, Small molecule, Visualization, Computer Science Applications, Lead (geology), chemistry, Amino Acid Sequence, Peptides, Peptide sequence, Sequence Alignment
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المؤلفون: Elizabeth Joshi, Andy Liaw, Prabha Karnachi, Meir Glick, Yuting Xu, Matthew Tudor, Robert P. Sheridan, Falgun Shah, Juan C. Alvarez, Alan C. Cheng
المصدر: Journal of Chemical Information and Modeling. 60:1969-1982
مصطلحات موضوعية: Quantitative structure–activity relationship, geography, geography.geographical_feature_category, 010304 chemical physics, Computer science, General Chemical Engineering, Uncertainty, Quantitative Structure-Activity Relationship, General Chemistry, Limiting, Library and Information Sciences, computer.software_genre, 01 natural sciences, Chemical space, 0104 chemical sciences, Computer Science Applications, Structure-Activity Relationship, 010404 medicinal & biomolecular chemistry, 0103 physical sciences, Cliff, Kurtosis, Scientific Experimental Error, Data mining, Noise (video), computer
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المؤلفون: Kelly Slocum, Jianmei Fan, Michael Dore, Palermo Mark G, Zhan Deng, Bakary-Barry Toure, Jorge Garcia-Fortanet, Dyuti Majumdar, Martin F. Hentemann, Nick Keen, Suzanne Zhu, Christopher Towler, Michael Shultz, William R. Sellers, Simon Mathieu, Denise Grunenfelder, Robert Koenig, Douglas C. Bauer, Shumei Liu, Jay Larrow, Victoriano Tamez, David Dunstan, Andreea Argintaru, Timothy Michael Ramsey, Zhouliang Chen, Gang Liu, Ying-Nan Chen, Rukundo Ntaganda, Bing Yu, Joanna Slisz, Hongyun Wang, Pascal D. Fortin, Christopher Sean Straub, Ji-Hu Zhang, Ping Wang, Laura R. LaBonte, Mitsunori Kato, Matthew J. Meyer, Fan Yang, Patrick James Sarver, Samuel B. Ho, Brant Firestone, Rajesh Karki, John F. Reilly, Troy Smith, Ho Man Chan, Cary Fridrich, John William Giraldes, Julie Boisclair, Chen Christine Hiu-Tung, Meir Glick, Zhao B. Kang, Morvarid Mohseni, Lawrence Blas Perez, Michael G. Acker, Sarah Williams, Matthew J. LaMarche, Martin Sendzik, Michelle Fodor, Huia-Xiang Hao, Peter Fekkes, Minying Pu, Travis Stams, Stanley Spence, Andriana Jouk
المصدر: Journal of medicinal chemistry. 63(22)
مصطلحات موضوعية: Drug, Programmed cell death, media_common.quotation_subject, Allosteric regulation, Antineoplastic Agents, Protein Tyrosine Phosphatase, Non-Receptor Type 11, Protein tyrosine phosphatase, Pharmacology, 01 natural sciences, 03 medical and health sciences, Mice, Dogs, Allosteric Regulation, In vivo, Neoplasms, Drug Discovery, medicine, Tumor Cells, Cultured, Animals, Humans, Enzyme Inhibitors, Gene, 030304 developmental biology, media_common, 0303 health sciences, Chemistry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, 0104 chemical sciences, Rats, PTPN11, 010404 medicinal & biomolecular chemistry, Macaca fascicularis, Molecular Medicine
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المؤلفون: Victoria Kutilek, Zhao Wang, Rafael Fernandez, James R. Tata, Li Zheng, Xuan Mo, Brian D. Dill, Meir Glick, Nirodhini Siriwardana, Jonathan D. Mortison, Ivan Cornella-Taracido, Brian M. Andresen, Julie Di Bernardo, Yuting Xu, Andy Liaw, Matthew Christopher, Oleg Ursu, Benjamin Ruprecht, Huijun Wang, An Chi
المصدر: Nature chemical biology. 16(10)
مصطلحات موضوعية: Lung cancer cell, Chemistry, Proteome, Cancer research, Cell Biology, Drug action, Mass spectrometry, Molecular Biology
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المؤلفون: James R. Tata, Oleg Ursu, Nirodhini Siriwardana, Brian M. Andresen, Li Zheng, Brian D. Dill, Benjamin Ruprecht, Huijun Wang, Matthew Christopher, Julie Di Bernardo, Ivan Cornella-Taracido, Zhao Wang, Victoria Kutilek, Jonathan D. Mortison, Andy Liaw, Meir Glick, An Chi, Yuting Xu, Rafael Fernandez, Xuan Mo
المصدر: Nature chemical biology. 16(10)
مصطلحات موضوعية: Proteomics, Lung Neoplasms, Proteome, medicine.drug_class, Antineoplastic Agents, Drug action, Computational biology, Mass Spectrometry, 03 medical and health sciences, Cell Line, Tumor, medicine, Humans, Molecular Biology, 030304 developmental biology, 0303 health sciences, Ceritinib, Chemistry, 030302 biochemistry & molecular biology, Autophagy, Cell Biology, ALK inhibitor, Gene Expression Regulation, Neoplastic, Proteostasis, Mechanism of action, medicine.symptom, medicine.drug
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المؤلفون: Meir Glick, Sean J. Fox, Charlie Chang, Erica Cook, Robert P. Sheridan, David M. Tellers, Iain M. Wallace, Dante A. Pertusi, Anne Mai Wassermann, Richard J. O. Barnard, Huijun Wang, Peter S. Kutchukian
المصدر: Drug Discovery Today. 23:151-160
مصطلحات موضوعية: 0301 basic medicine, Databases, Factual, Computer science, Automatic identification and data capture, 01 natural sciences, Set (abstract data type), 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Chemogenomics, Pharmaceutical industry, Pharmacology, Structure (mathematical logic), Biological data, business.industry, Genomics, Models, Theoretical, Data science, 0104 chemical sciences, Visualization, 010404 medicinal & biomolecular chemistry, Phenotype, 030104 developmental biology, chemistry, business, Model building
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المؤلفون: Michelle F. Homsher, Louis Locco, Shannon L. Stahler, Michael Weber, Jennifer E. Nothstein, Eleftheria N. Finger, Evelyn Boots, Mee Ra Heo, Amita Patel, Gregory O'Donnell, Alex Wolicki, Michael F.A. Finley, J. Christopher Culberson, Paul Zuck, Juncai Meng, Kenneth Roberts, David J. Bell, Peter S. Kutchukian, Gregory C. Adam, Carissa Quinn, Patrick Cocchiarella, Meir Glick, S. Alex May, Victor N. Uebele, Edward Hudak, Brian Squadroni, Daniel Riley, Andrew Rusinko, Kelli Solly, Michelle Hartnett, Dante A. Pertusi, Adam Amoss, Anthony Kreamer, Tara White, Anne Mai Wassermann
المصدر: SLAS Discovery. 22:995-1006
مصطلحات موضوعية: 0301 basic medicine, Prioritization, Engineering, Drug Evaluation, Preclinical, computer.software_genre, 01 natural sciences, Biochemistry, Analytical Chemistry, Machine Learning, User-Computer Interface, 03 medical and health sciences, Heuristics, Iterative and incremental development, Virtual screening, Drug discovery, business.industry, 0104 chemical sciences, Weighting, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Cheminformatics, Benchmark (computing), Molecular Medicine, Data mining, business, computer, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561e5ff95861fbde45cdff3f2132d673
https://doi.org/10.1177/2472555217706058 -
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المؤلفون: Peter Saradjian, John P. Santa Maria, Peter J. Dandliker, Chad Chamberlin, Gregory C. Adam, Nicholas Murgolo, Clifton E. Barry, Elliott B. Nickbarg, Paul Zuck, Peter S. Kutchukian, Charles G. Garlisi, Lihu Yang, Yumi Park, Helena I. Boshoff, Katherine Young, David B. Olsen, Meir Glick, Michael D. Altman
المصدر: ACS Chemical Biology. 12:2448-2456
مصطلحات موضوعية: 0301 basic medicine, Phenotypic screening, Antitubercular Agents, Drug Evaluation, Preclinical, Computational biology, Ligands, Bioinformatics, Biochemistry, Article, Mycobacterium tuberculosis, 03 medical and health sciences, Dihydrofolate reductase, High-Throughput Screening Assays, Humans, Tuberculosis, biology, General Medicine, biology.organism_classification, Molecular Docking Simulation, Tetrahydrofolate Dehydrogenase, 030104 developmental biology, biology.protein, Folic Acid Antagonists, Molecular Medicine, HeLa Cells
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المؤلفون: Chris L. Waller, Charlie Zhenyu Chang, Frank K Brown, Farida Kopti, Scott A. Johnson, Meir Glick
المصدر: The AAPS Journal. 19:1255-1263
مصطلحات موضوعية: 0301 basic medicine, Information management, Information Management, Computer science, Process (engineering), business.industry, Data manipulation language, Decision Making, 05 social sciences, 050301 education, Pharmaceutical Science, Information technology, Data science, Application lifecycle management, 03 medical and health sciences, 030104 developmental biology, Workflow, Data access, Drug Discovery, business, 0503 education, Agile software development