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المؤلفون: Susana R. Louros, Sang S. Seo, Beatriz Maio, Cristina Martinez-Gonzalez, Miguel A. Gonzalez-Lozano, Melania Muscas, Nick C. Verity, Jimi C. Wills, Ka Wan Li, Matthew F. Nolan, Emily K. Osterweil
المساهمون: Molecular and Cellular Neurobiology, AIMMS, Amsterdam Neuroscience - Cellular & Molecular Mechanisms, Amsterdam Neuroscience - Neurodegeneration
المصدر: Louros, S R, Seo, S S, Maio, B, Martinez-Gonzalez, C, Gonzalez-Lozano, M A, Muscas, M, Verity, N C, Wills, J C, Li, K W, Nolan, M F & Osterweil, E K 2023, ' Excessive proteostasis contributes to pathology in fragile X syndrome ', Neuron, vol. 111, no. 4, pp. 508-525.e7 . https://doi.org/10.1016/j.neuron.2022.11.012
Ribeiro dos Louros, S, Seo, S, Maio, B, Martinez Gonzalez, C, Gonzalez-Lozano, M A, Muscas, M, Verity, N, Wills, J, Li, K W, Nolan, M F & Osterweil, E 2022, ' Excessive proteostasis contributes to pathology in Fragile X Syndrome ', Neuron . https://doi.org/10.1016/j.neuron.2022.11.012
Neuron, 111(4), 508-525.e7. Cell Pressمصطلحات موضوعية: AGS, proteostasis, General Neuroscience, bortezomib, fragile X, PSMB5, UPS, inferior colliculus, proteasome, SDG 3 - Good Health and Well-being, FMR1, seizures
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8a1937580ea55c98a7617827e2f94e
https://doi.org/10.1016/j.neuron.2022.11.012 -
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المؤلفون: Sang S. Seo, Melania Muscas, Susana R. Louros, Emily K. Osterweil
المصدر: eNeuro
Muscas, M, Seo, S, Louros, S R & Osterweil, E 2020, ' A differential effect of lovastatin versus simvastatin in neurodevelopmental disorders ', eNeuro . https://doi.org/10.1523/ENEURO.0162-20.2020مصطلحات موضوعية: MAPK/ERK pathway, Drug, Simvastatin, Statin, medicine.drug_class, media_common.quotation_subject, autism, fragile X, lovastatin, Pharmacology, fmr1, polycyclic compounds, medicine, Humans, media_common, business.industry, organic chemicals, General Neuroscience, Anticholesteremic Agents, nutritional and metabolic diseases, General Medicine, medicine.disease, FMR1, Fragile X syndrome, ERK, Neurodevelopmental Disorders, Fragile X Syndrome, Commentary, Autism, lipids (amino acids, peptides, and proteins), Disorders of the Nervous System, Lovastatin, business, medicine.drug
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c288c29d6955089fbde1c9226e5881e0
https://pubmed.ncbi.nlm.nih.gov/32651266 -
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المؤلفون: Susana R. Louros, Melania Muscas, Emily K. Osterweil
المصدر: eNeuro
Muscas, M, Ribeiro dos Louros, S & Osterweil, E 2019, ' Lovastatin, not simvastatin, corrects core phenotypes in the fragile X mouse model ', eNeuro, vol. 6, no. 3 . https://doi.org/10.1523/ENEURO.0097-19.2019مصطلحات موضوعية: MAPK/ERK pathway, Male, Simvastatin, fragile X, lovastatin, Hippocampal formation, Pharmacology, Hippocampus, 0302 clinical medicine, polycyclic compounds, Hippocampus (mythology), Medicine, FMR1, media_common, 0303 health sciences, General Neuroscience, Anticholesteremic Agents, 3.1, General Medicine, New Research, Phenotype, Penetrance, 3. Good health, Fragile X syndrome, ERK, lipids (amino acids, peptides, and proteins), Lovastatin, medicine.drug, Drug, MAP Kinase Signaling System, media_common.quotation_subject, Mice, Transgenic, Epilepsy, Reflex, 03 medical and health sciences, Potency, Animals, 030304 developmental biology, business.industry, organic chemicals, nutritional and metabolic diseases, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, Acoustic Stimulation, Fragile X Syndrome, Protein Biosynthesis, Autism, Disorders of the Nervous System, business, 030217 neurology & neurosurgery
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9a0b6e299b202e14304e3e0dbc9de7
https://pubmed.ncbi.nlm.nih.gov/31147392 -
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المؤلفون: Sophie R, Thomson, Sang S, Seo, Stephanie A, Barnes, Susana R, Louros, Melania, Muscas, Owen, Dando, Caoimhe, Kirby, David J A, Wyllie, Giles E, Hardingham, Peter C, Kind, Emily K, Osterweil
المصدر: Neuron
مصطلحات موضوعية: Neurons, protein synthesis, Long-Term Synaptic Depression, fragile X, autism, Mice, Transgenic, Receptors, Metabotropic Glutamate, Hippocampus, Article, Methoxyhydroxyphenylglycol, TRAP, Disease Models, Animal, Fragile X Mental Retardation Protein, muscarinic receptor, Fragile X Syndrome, Protein Biosynthesis, m4, LTD, Animals, mglur theory, FMRP, FMR1
