المؤلفون: Christian M. Nefzger, author^{1, 2}, Sara Alaei, author^{1, 2}, Anja S. Knaupp, author^{1, 2}, Melissa L. Holmes, author^{1, 2}, Jose M. Polo, author^{1, 2}

المصدر: Journal of Visualized Experiments. (91)

الإتاحة: http://www.jove.com/video/51728

المؤلفون: Cheng Huang, Jaber Firas, Partha Pratim Das, Yu Bo Yang Sun, Anja S Knaupp, Joseph Chen, Melissa L. Holmes, Christian M. Nefzger, Fernando J. Rossello, Pratibha Tripathi, Trung V. Nguyen, Ralf B. Schittenhelm, Sue Mei Lim, Kayla Wong, Xiaodong Liu, Monika Mohenska, Jody J. Haigh, Jan Schröder, Ryan Lister, Jahnvi Pflueger, Kathryn C. Davidson, Ethan Ford, Jose M. Polo, Michael R. Larcombe

المصدر: Stem Cell Reports

مصطلحات موضوعية: 0301 basic medicine, Homeobox protein NANOG, Human Embryonic Stem Cells, iPSCs, TINC, Biology, Nanog, Biochemistry, Article, single-locus pull-down, 03 medical and health sciences, 0302 clinical medicine, Genetics, Humans, Epigenetics, Induced pluripotent stem cell, Gene, Transcription factor, RCOR2, reprogramming, Nanog Homeobox Protein, Cell Biology, Epigenome, pluripotency, 3. Good health, Cell biology, 030104 developmental biology, Genetic Loci, Multiprotein Complexes, transcriptional complex, Co-Repressor Proteins, Reprogramming, 030217 neurology & neurosurgery, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb069fae910ab47ceb5d6cea44adf7d
https://doi.org/10.1016/j.stemcr.2020.11.005

المؤلفون: Sara Alaei, Minna-Liisa Änkö, Melissa L. Holmes, Anja S Knaupp, Jose M. Polo, Sue Mei Lim, Christian M. Nefzger, Joseph Chen

المصدر: Stem Cell Research, Vol 17, Iss 1, Pp 49-53 (2016)

مصطلحات موضوعية: Transcriptional Activation, 0301 basic medicine, Octamer Transcription Factor-3, Cellular differentiation, Induced Pluripotent Stem Cells, Kruppel-Like Transcription Factors, Biology, Proto-Oncogene Proteins c-myc, Kruppel-Like Factor 4, Mice, 03 medical and health sciences, Transactivation, Plasmid, Animals, Induced pluripotent stem cell, Gene, lcsh:QH301-705.5, Cells, Cultured, Genetics, Medicine(all), SOXB1 Transcription Factors, Teratoma, Cell Differentiation, General Medicine, Cell Biology, Fibroblasts, Cellular Reprogramming, Cell biology, 030104 developmental biology, lcsh:Biology (General), Tetracyclines, Reprogramming, Plasmids, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90f9a2861d80e2c5f3cceb1010bc486

المؤلفون: Matt E. Oates, Harukazu Suzuki, Christian M. Nefzger, Owen J. L. Rackham, Jose M. Polo, Alistair R. R. Forrest, Carsten O. Daub, Enrico Petretto, Yoshihide Hayashizaki, Jaber Firas, Jay W. Shin, Hai Fang, Julian Gough, Anja S Knaupp, Melissa L. Holmes

المصدر: Rackham, O J L, Firas, J, Fang, H, Oates, M E, Holmes, M L, Knaupp, A S, Suzuki, H, Nefzger, C M, Daub, C O, Shin, J W, Petretto, E, Forrest, A R R, Hayashizaki, Y & Polo, J M & Gough, J 2016, ' A predictive computational framework for direct reprogramming between human cell types ', Nature Genetics, vol. 48, no. 3, pp. 331-335 . https://doi.org/10.1038/ng.3487

مصطلحات موضوعية: 0301 basic medicine, Cell type, Induced Pluripotent Stem Cells, Cell, Computational biology, Biology, Regenerative Medicine, Bioinformatics, Regenerative medicine, 03 medical and health sciences, Genetics, medicine, Humans, Gene Regulatory Networks, Tissue engineering, Transcription factor, Regulation of gene expression, System analysis, Transdifferentiation, Cell Differentiation, Fibroblasts, Human cell, Cellular Reprogramming, Gene regulation, 030104 developmental biology, medicine.anatomical_structure, Cell Transdifferentiation, Reprogramming, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a441d839ee3859233a23cecc47bc9649
https://doi.org/10.1038/ng.3487

المؤلفون: Sam Buckberry, Sara Alaei, Susan J. Clark, Alex de Mendoza, Sue Mei Lim, Fernando J. Rossello, Christian M. Nefzger, Jaber Firas, Jahnvi Pflueger, Ryan Lister, Melissa L. Holmes, Anja S Knaupp, Ethan Ford, Michael R. Larcombe, Shalima S. Nair, Jose M. Polo

المصدر: Cell Stem Cell. 21:834-845.e6

مصطلحات موضوعية: 0301 basic medicine, Cell Biology, Biology, Embryonic stem cell, Chromatin remodeling, Chromatin, Cell biology, ChIP-sequencing, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, SOX2, Genetics, Molecular Medicine, sense organs, Induced pluripotent stem cell, Transcription factor, Reprogramming, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1d993661ae3321d29967ef16d0550188
https://doi.org/10.1016/j.stem.2017.11.007

المؤلفون: Dileepa Diyagama, Gordon K. Smyth, Melissa L. Holmes, Matthew E. Ritchie, Alicia Oshlack, Jeremy D. Silver, Andrew J. Holloway

المصدر: Bioinformatics. 23:2700-2707

مصطلحات موضوعية: Statistics and Probability, False discovery rate, Normalization (statistics), Microarray, Microarray analysis techniques, Computer science, Reproducibility of Results, Estimator, In situ hybridization, Image Enhancement, Sensitivity and Specificity, Biochemistry, Computer Science Applications, Computational Mathematics, Microscopy, Fluorescence, Multiphoton, Computational Theory and Mathematics, Background Correction, Image Interpretation, Computer-Assisted, Statistics, DNA microarray, Artifacts, Molecular Biology, In Situ Hybridization, Fluorescence, Oligonucleotide Array Sequence Analysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a1a2000f1e67d5e91611262e843730
https://doi.org/10.1093/bioinformatics/btm412

المؤلفون: Melissa L. Holmes, Clare Pridans, Sebastian Carotta, Stephen L. Nutt

المصدر: Carotta, S, Holmes, ML, Pridans, C & Nutt, SL 2006, ' Pax5 maintains cellular identity by repressing gene expression throughout B cell differentiation. ', Cell Cycle, vol. 5, no. 21, pp. 2452 . < http://www.ncbi.nlm.nih.gov/pubmed/17102626 >

مصطلحات موضوعية: Transcription, Genetic, Cell Survival, PAX5 Transcription Factor, Cellular differentiation, Plasma Cells, B-Lymphocytes/cytology, Immunoglobulins, Biology, Lymphocyte Activation, Models, Biological, immune system diseases, hemic and lymphatic diseases, Plasma cell differentiation, medicine, Hematopoietic Stem Cells/metabolism, Animals, Humans, Gene silencing, Cell Lineage, B-Lymphocytes/metabolism, Lymphopoiesis, Molecular Biology, Psychological repression, B cell, Genetics, Regulation of gene expression, Immunoglobulins/metabolism, B-Lymphocytes, Cell Differentiation, Cell Biology, B-Cell-Specific Activator Protein/metabolism, Hematopoietic Stem Cells, Plasma Cells/cytology, medicine.anatomical_structure, Gene Expression Regulation, B-Cell-Specific Activator Protein/physiology, Signal Transduction, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443f35bb4fa42c53d93ff83c3de94791
https://doi.org/10.4161/cc.5.21.3396

المؤلفون: Sebastian Carotta, Stephen L. Nutt, Melissa L. Holmes, Lynn M. Corcoran

المصدر: Genes & Development. 20:933-938

مصطلحات موضوعية: Chromatin Immunoprecipitation, PAX5 Transcription Factor, Electrophoretic Mobility Shift Assay, Biology, Polymerase Chain Reaction, Cell Line, Mice, Research Communication, fluids and secretions, immune system diseases, Transcription (biology), hemic and lymphatic diseases, Genetics, Animals, Cell Lineage, Progenitor cell, Receptor, Transcription factor, Psychological repression, B-Lymphocytes, Gene Expression Regulation, Developmental, hemic and immune systems, Flow Cytometry, fms-Like Tyrosine Kinase 3, embryonic structures, Fms-Like Tyrosine Kinase 3, Chromatin immunoprecipitation, Protein Binding, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04888017e6fd982c3e956aedd1ce68db
https://doi.org/10.1101/gad.1396206

المؤلفون: Stuart H. Orkin, Karin M.L. Gaensler, Merlin Crossley, Beng H. Chong, Robert Czoli, Jeremy Turner, Philip Koh, Andrew C. Perkins, Melissa L. Holmes, Yuko Fujiwara, Haidi Yang

المصدر: Blood Cells, Molecules, and Diseases. 31:125-170

مصطلحات موضوعية: Silence, Genetics, Co repressor, BASIC KRUPPEL-LIKE FACTOR, Gene expression, Molecular Medicine, Repressor, Cell Biology, Hematology, Biology, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c82dfa2a5acae6e72bb5b7fa6e8cc8cf
https://doi.org/10.1016/s1079-9796(03)00043-3

المؤلفون: Levon M. Khachigian, Anthea L. Newton, Merlin Crossley, Beng H. Chong, Michael Eisbacher, Philip J. Hogg, Melissa L. Holmes

المصدر: Molecular and Cellular Biology. 23:3427-3441

مصطلحات موضوعية: DNA, Complementary, Proto-Oncogene Protein c-fli-1, Recombinant Fusion Proteins, Cellular differentiation, Amino Acid Motifs, Blotting, Western, Immunoblotting, Cell Separation, Biology, Transfection, DNA-binding protein, Genes, Reporter, Proto-Oncogene Proteins, Two-Hybrid System Techniques, Humans, GATA1 Transcription Factor, Promoter Regions, Genetic, Molecular Biology, Transcription factor, Gene Library, Glutathione Transferase, Transcriptional Regulation, Zinc finger transcription factor, Zinc finger, ETS transcription factor family, fungi, Cell Differentiation, Zinc Fingers, Promoter, DNA, Cell Biology, Blotting, Northern, Flow Cytometry, Precipitin Tests, Molecular biology, Protein Structure, Tertiary, DNA-Binding Proteins, Kinetics, Trans-Activators, Erythroid-Specific DNA-Binding Factors, RNA, Erratum, K562 Cells, Megakaryocytes, HeLa Cells, Protein Binding, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f2143a275eb0021fdabe0849d81c8f
https://doi.org/10.1128/mcb.23.10.3427-3441.2003