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1كتاب إلكترونيThe Design, Development, and Evaluation of BACE1 Inhibitors for the Treatment of Alzheimer’s Disease
المؤلفون: Ghosh, Arun K.Aff11, Aff12, Cárdenas, Emilio L.Aff11, Osswald, Heather L.Aff11
المساهمون: Bernstein, Peter R., Series editorAff1, Georg, Gunda I., Series editorAff2, Keller, Thomas, Series editorAff3, Lowe, John A., Series editorAff4, Meanwell, Nicholas A., Series editorAff5, Saxena, Anil Kumar, Series editorAff6, Stilz, Ulrich, Series editorAff7, Supuran, Claudiu T., Series editorAff8, Zhang, Ao, Series editorAff9, Wolfe, Michael S., editorAff10
المصدر: Alzheimer’s Disease II. 24:27-85
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2دورية أكاديمية
المؤلفون: Tang, JordanAff1, Aff2, IDArt203299_cor1, Ghosh, Arun K., Hong, Lin, Koelsch, Gerald, Turner, Robert T.Aff1, Aff2, Chang, Wanpin
المصدر: Journal of Molecular Neuroscience. 20(3):299-304
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المؤلفون: Nagaswamy Kumaragurubaran, Koena Ghosh, Andrew D. Mesecar, Arun K. Ghosh, Emma K. Lendy, Jordan Tang, Margherita Brindisi, Yu-Chen Yen, Xiangping Huang
المساهمون: Ghosh, A. K., Ghosh, K., Brindisi, M., Lendy, E. K., Yen, Y. -C., Kumaragurubaran, N., Huang, X., Tang, J., Mesecar, A. D.
مصطلحات موضوعية: 0301 basic medicine, Amide, Clinical Biochemistry, Carboxylic Acids, Pharmaceutical Science, Crystallography, X-Ray, 01 natural sciences, Biochemistry, Isoxazole, Catalytic Domain, Drug Discovery, Aspartic Acid Endopeptidases, β-secretase, Aspartic Acid Endopeptidase, Amyloid Precursor Protein Secretase, Memapsin 2, Alanine, Crystallography, biology, Bicyclic molecule, Molecular Structure, Chemistry, BACE-1, Alzheimer's disease, symbols, Molecular Medicine, van der Waals force, Carboxylic Acid, Human, Stereochemistry, Isoxazoline, Amides, Amyloid Precursor Protein Secretases, Bridged Bicyclo Compounds, Cysteine, Humans, Isoxazoles, Protease Inhibitors, 010402 general chemistry, Article, 03 medical and health sciences, symbols.namesake, mental disorders, Hydrolase, Molecule, Molecular Biology, Ligand, Organic Chemistry, Active site, 0104 chemical sciences, 030104 developmental biology, biology.protein, X-Ray, Bridged Bicyclo Compound
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ab8582625d739744a324e7c35a80f3
http://hdl.handle.net/11588/771102 -
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المؤلفون: Andrew D. Mesecar, Thippeswamy Devasamudram, Xiao Ming Xu, Jordan Tang, Yu-Chen Yen, Xiangping Huang, Gerald Koelsch, Arun K. Ghosh, Geoffrey Bilcer, Margherita Brindisi, Hui Lei
المساهمون: Ghosh, Arun K., Brindisi, Margherita, Yen, Yu Chen, Xu, Xiaoming, Huang, Xiangping, Devasamudram, Thippeswamy, Bilcer, Geoffrey, Lei, Hui, Koelsch, Gerald, Mesecar, Andrew D., Tang, Jordan
المصدر: Bioorganic & Medicinal Chemistry Letters. 25:668-672
مصطلحات موضوعية: Protease Inhibitor, Clinical Biochemistry, Pharmaceutical Science, Pyrazole, Crystallography, X-Ray, Ligands, Biochemistry, chemistry.chemical_compound, Catalytic Domain, Drug Discovery, β-secretase, Moiety, Amyloid Precursor Protein Secretase, Alzheimer's disease, BACE-1, Memapsin 2, Protease inhibitors, Amyloid Precursor Protein Secretases, Binding Sites, Kinetics, Molecular Dynamics Simulation, Protease Inhibitors, Protein Binding, Pyrazoles, Structure-Activity Relationship, Thiazoles, Drug Design, Molecular Medicine, Molecular Biology, 3003, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, Crystallography, biology, Stereochemistry, Ligand, Article, Structure–activity relationship, Binding site, Thiazole, Kinetic, Binding Site, Active site, Combinatorial chemistry, chemistry, X-Ray, biology.protein, Amyloid precursor protein secretase
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المؤلفون: Andrew D. Mesecar, Emilio L. Cárdenas, Jordan Tang, Yu-Chen Yen, Margherita Brindisi, Xiangping Huang, Nagaswamy Kumaragurubaran, Jean Rene Ella-Menye, Arun K. Ghosh
المساهمون: Ghosh, Arun K., Brindisi, Margherita, Yen, Yu-Chen, Cã¡rdenas, Emilio L., Ella-Menye, Jean-Rene, Kumaragurubaran, Nagaswamy, Huang, Xiangping, Tang, Jordan, Mesecar, Andrew D.
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Clinical Biochemistry, Phthalic Acids, Pharmaceutical Science, Crystal structure, 01 natural sciences, Biochemistry, Piperazines, Article, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, β-Secretase, mental disorders, Drug Discovery, Aspartic Acid Endopeptidases, Structure–activity relationship, Aspartic Acid Endopeptidase, Amyloid Precursor Protein Secretase, Memapsin 2, Phthalic Acid, Piperazine, Molecular Biology, Bicyclic molecule, 010405 organic chemistry, BACE-1, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, X-ray, Protease inhibitors, Alzheimer's disease, 0104 chemical sciences, Phthalic acid, 030104 developmental biology, Design synthesis, chemistry, Protease inhibitor, β secretase, Amyloid Precursor Protein Secretases, Molecular Medicine, 3003
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae81974b3994c5ead563c93b995ec91
http://hdl.handle.net/11588/771128 -
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المؤلفون: Gerald Koelsch, Wan-Pin Chang, Xiangyuan He, Jordan Tang
المصدر: FEBS Letters. 524:183-187
مصطلحات موضوعية: DNA, Complementary, ADP ribosylation factor, Endosome, β-Secretase, Molecular Sequence Data, Biophysics, GGA2, GGA1, Biology, Endocytosis, Biochemistry, 03 medical and health sciences, Cytosol, 0302 clinical medicine, Structural Biology, Endopeptidases, Genetics, Aspartic Acid Endopeptidases, Humans, Amino Acid Sequence, Cloning, Molecular, Binding site, Memapsin 2, Molecular Biology, Peptide sequence, 030304 developmental biology, 0303 health sciences, Binding Sites, Sequence Homology, Amino Acid, ADP-Ribosylation Factors, Proteins, Cell Biology, Cell biology, Adaptor Proteins, Vesicular Transport, Memapsin 1, biology.protein, Amyloid Precursor Protein Secretases, Carrier Proteins, Alzheimer’s disease, Amyloid precursor protein secretase, 030217 neurology & neurosurgery
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7دورية أكاديمية
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8دورية أكاديمية
لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل. -
9دورية أكاديمية
لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل. -
10دورية أكاديمية
لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.