المؤلفون: Shokat, Kevan, Wohlbold, L, Merrick, KA, De, S, Amat, R, Kim, JH, Larochelle, S, Allen, JJ, Zhang, C, Shokat, KM, Petrini, JHJ

URL الوصول: https://escholarship.org/uc/item/0692b8sb

المؤلفون: Suarez-Lopez, L, De la Rosa, X, Sriram, G, Kong, YW, Morandell, S, Merrick, KA, Hernandez, Y, Villablanca, EJ, Haigis, KM, Yaffe, MB

المصدر: SHOCK. 51(6):41-42

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:141638381

المؤلفون: Chen JK; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Merrick KA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Kong YW; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Izrael-Tomasevic A; Genentech Biotechnology company, South San Francisco, CA 94080, USA., Eng G; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Handly ED; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Patterson JC; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Cannell IG; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Suarez-Lopez L; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Hosios AM; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Dinh A; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Kirkpatrick DS; Genentech Biotechnology company, South San Francisco, CA 94080, USA., Yu K; Genentech Biotechnology company, South San Francisco, CA 94080, USA., Rose CM; Genentech Biotechnology company, South San Francisco, CA 94080, USA., Hernandez JM; Surgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Hwangbo H; Curriculum in Bioinformatics and Computational Biology, UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Pharmacology, Computational Medicine Program, and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Palmer AC; Department of Pharmacology, Computational Medicine Program, and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Vander Heiden MG; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02215, USA., Yilmaz ÖH; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Yaffe MB; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Surgery, Beth Israel Medical Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.; Surgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Apr 29. Date of Electronic Publication: 2023 Apr 29.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Bronner SM; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States. Electronic address: sbronner@mazetx.com., Merrick KA; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Murray J; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Salphati L; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Moffat JG; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Pang J; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Sneeringer CJ; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Dompe N; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Cyr P; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Purkey H; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Boenig GL; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Li J; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Kolesnikov A; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Larouche-Gauthier R; Paraza Pharma, Inc., 2525 Ave. Marie-Curie, Montreal, QC H4S 2E1, Canada., Lai KW; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Shen X; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Aubert-Nicol S; Paraza Pharma, Inc., 2525 Ave. Marie-Curie, Montreal, QC H4S 2E1, Canada., Chen YC; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Cheong J; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Crawford JJ; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Hafner M; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Haghshenas P; Paraza Pharma, Inc., 2525 Ave. Marie-Curie, Montreal, QC H4S 2E1, Canada., Jakalian A; Paraza Pharma, Inc., 2525 Ave. Marie-Curie, Montreal, QC H4S 2E1, Canada., Leclerc JP; Paraza Pharma, Inc., 2525 Ave. Marie-Curie, Montreal, QC H4S 2E1, Canada., Lim NK; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., O'Brien T; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Plise EG; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Shalan H; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Sturino C; Paraza Pharma, Inc., 2525 Ave. Marie-Curie, Montreal, QC H4S 2E1, Canada., Wai J; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Xiao Y; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Yin J; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Zhao L; Paraza Pharma, Inc., 2525 Ave. Marie-Curie, Montreal, QC H4S 2E1, Canada., Gould S; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Olivero A; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Heffron TP; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States. Electronic address: heffron.timothy@gene.com.

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Aug 15; Vol. 29 (16), pp. 2294-2301. Date of Electronic Publication: 2019 Jun 26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Antineoplastic Agents/*pharmacology , Brain Neoplasms/*drug therapy , Cyclin-Dependent Kinase 4/*antagonists & inhibitors , Cyclin-Dependent Kinase 6/*antagonists & inhibitors , Glioblastoma/*drug therapy , Protein Kinase Inhibitors/*pharmacology, Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cyclin-Dependent Kinase 4/metabolism ; Cyclin-Dependent Kinase 6/metabolism ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Humans ; MCF-7 Cells ; Molecular Structure ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Structure-Activity Relationship

المؤلفون: Suarez-Lopez L; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142.; Center for Personalized Cancer Medicine, David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142.; Cancer Research Institute and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Sriram G; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142.; Center for Personalized Cancer Medicine, David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142., Kong YW; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142.; Center for Personalized Cancer Medicine, David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142., Morandell S; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142.; Center for Personalized Cancer Medicine, David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142., Merrick KA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142.; Center for Personalized Cancer Medicine, David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142., Hernandez Y; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142.; Center for Personalized Cancer Medicine, David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142., Haigis KM; Cancer Research Institute and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Harvard Digestive Disease Center, Harvard Medical School, Boston, MA 02215., Yaffe MB; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142; myaffe@mit.edu.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142.; Center for Personalized Cancer Medicine, David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142.; Divisions of Acute Care Surgery, Trauma, and Surgical Critical Care and Surgical Oncology, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 May 01; Vol. 115 (18), pp. E4236-E4244. Date of Electronic Publication: 2018 Apr 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Colorectal Neoplasms/*blood supply , Colorectal Neoplasms/*epidemiology , Intracellular Signaling Peptides and Proteins/*metabolism , Macrophages/*enzymology , Neoplasm Proteins/*metabolism , Neovascularization, Pathologic/*enzymology , Protein Serine-Threonine Kinases/*metabolism, Animals ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Intracellular Signaling Peptides and Proteins/genetics ; Macrophages/pathology ; Mice ; Mice, Knockout ; Neoplasm Proteins/genetics ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/pathology ; Protein Serine-Threonine Kinases/genetics

المؤلفون: Cannell IG, Merrick KA, Morandell S, Zhu CQ, Braun CJ, Grant RA, Cameron ER, Tsao MS, Hemann MT, Yaffe MB

المصدر: Cancer cell [Cancer Cell] 2015 Dec 14; Vol. 28 (6), pp. 831. Date of Electronic Publication: 2015 Dec 14.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: PubMed not MEDLINE

المؤلفون: Schachter MM; Department of Structural and Chemical Biology, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029-6574, USA., Merrick KA, Larochelle S, Hirschi A, Zhang C, Shokat KM, Rubin SM, Fisher RP

المصدر: Molecular cell [Mol Cell] 2013 Apr 25; Vol. 50 (2), pp. 250-60.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: G1 Phase* , Protein Processing, Post-Translational*, Cyclin-Dependent Kinase 4/*metabolism , Cyclin-Dependent Kinases/*metabolism, Amino Acid Motifs ; Cell Proliferation ; Cyclin D/metabolism ; Cyclin H/metabolism ; Cyclin-Dependent Kinase 2/metabolism ; Cyclin-Dependent Kinase 4/genetics ; Cyclin-Dependent Kinase 6/metabolism ; Cyclin-Dependent Kinases/genetics ; Enzyme Activation ; Epistasis, Genetic ; HCT116 Cells ; Humans ; Phosphorylation ; Retinoblastoma Protein/metabolism ; S Phase ; Cyclin-Dependent Kinase-Activating Kinase

المؤلفون: Wohlbold L; Department of Structural and Chemical Biology, Mount Sinai School of Medicine, New York, New York, USA., Merrick KA, De S, Amat R, Kim JH, Larochelle S, Allen JJ, Zhang C, Shokat KM, Petrini JH, Fisher RP

المصدر: PLoS genetics [PLoS Genet] 2012 Aug; Vol. 8 (8), pp. e1002935. Date of Electronic Publication: 2012 Aug 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Radiation, Ionizing*, Cell Cycle Proteins/*metabolism , Cyclin-Dependent Kinase 2/*metabolism , DNA Damage/*radiation effects , Nuclear Proteins/*metabolism, Acid Anhydride Hydrolases ; Cell Cycle ; DNA Repair ; DNA Repair Enzymes/metabolism ; DNA-Binding Proteins/metabolism ; MRE11 Homologue Protein ; Phosphorylation

المؤلفون: Merrick KA; Department of Structural and Chemical Biology, Mount Sinai School of Medicine, New York, NY, USA., Fisher RP

المصدر: Cell cycle (Georgetown, Tex.) [Cell Cycle] 2012 Jul 15; Vol. 11 (14), pp. 2600-5. Date of Electronic Publication: 2012 Jul 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137841 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1551-4005 (Electronic) Linking ISSN: 15514005 NLM ISO Abbreviation: Cell Cycle Subsets: MEDLINE

مواضيع طبية MeSH: Cyclin-Dependent Kinases/*metabolism, Cyclin-Dependent Kinase 2/metabolism ; Cyclin-Dependent Kinases/antagonists & inhibitors ; Cyclins/metabolism ; Drug Evaluation, Preclinical ; G1 Phase ; Gene Targeting ; HCT116 Cells ; Humans ; S Phase

المؤلفون: Horiuchi D; Department of Medicine, University of California, San Francisco, CA 94143, USA., Huskey NE, Kusdra L, Wohlbold L, Merrick KA, Zhang C, Creasman KJ, Shokat KM, Fisher RP, Goga A

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 Apr 24; Vol. 109 (17), pp. E1019-27. Date of Electronic Publication: 2012 Apr 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Cell Transformation, Neoplastic* , Oncogenes*, Cyclin-Dependent Kinase 2/*physiology, Animals ; Cell Adhesion ; Cell Line, Tumor ; Cell Proliferation ; Colonic Neoplasms/enzymology ; Colonic Neoplasms/pathology ; Cyclin-Dependent Kinase 2/antagonists & inhibitors ; Cyclin-Dependent Kinase 2/chemistry ; Cyclin-Dependent Kinase 2/genetics ; Gene Knockdown Techniques ; Humans ; Mice ; RNA, Small Interfering