المؤلفون: Leifelt J; Department of Cellular and Molecular Medicine, The Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Dziegiel MH; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Immunology, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark., Brahm J; Department of Cellular and Molecular Medicine, The Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

المصدر: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2024 Mar 01; Vol. 326 (3), pp. C905-C916. Date of Electronic Publication: 2024 Jan 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Urea Transporters* , Urea* , Methylurea Compounds*, Humans ; Thiourea/pharmacology ; Erythrocytes

المؤلفون: Kang JM; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea., Kwon SO; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea., Ann J; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea., Blumberg PM; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea., Ha H; Medifron DBT, Seoul 08502, Republic of Korea., Yoo YD; Medifron DBT, Seoul 08502, Republic of Korea., Frank-Foltyn R; Grünenthal Innovation, Grünenthal GmbH, D-52078 Aachen, Germany., Lesch B; Grünenthal Innovation, Grünenthal GmbH, D-52078 Aachen, Germany., Bahrenberg G; Grünenthal Innovation, Grünenthal GmbH, D-52078 Aachen, Germany., Stockhausen H; Grünenthal Innovation, Grünenthal GmbH, D-52078 Aachen, Germany., Christoph T; Grünenthal Innovation, Grünenthal GmbH, D-52078 Aachen, Germany., Lee J; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: jeewoo@snu.ac.kr.

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2020 Dec 01; Vol. 30 (23), pp. 127548. Date of Electronic Publication: 2020 Sep 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Indazoles/*pharmacology , Methylurea Compounds/*pharmacology , Pyrazoles/*pharmacology , TRPV Cation Channels/*antagonists & inhibitors, Analgesics/chemical synthesis ; Analgesics/pharmacology ; Animals ; Body Temperature/drug effects ; CHO Cells ; Capsaicin/pharmacology ; Cricetulus ; Humans ; Indazoles/chemical synthesis ; Methylurea Compounds/chemical synthesis ; Mice ; Molecular Structure ; Pyrazoles/chemical synthesis ; Structure-Activity Relationship ; TRPV Cation Channels/agonists

المؤلفون: Yang J; School of Materials Science and Engineering , Shijiazhuang Tiedao University , Shijiazhuang , Hebei Province 050043 , China., Liu T; School of Materials Science and Engineering , Shijiazhuang Tiedao University , Shijiazhuang , Hebei Province 050043 , China.; Key Laboratory of Non-point Source Pollution Control, Ministry of Agriculture, Institute of Agricultural Resources and Regional Planning , Chinese Academy of Agricultural Sciences , Beijing 100081 , China., Liu H; Key Laboratory of Non-point Source Pollution Control, Ministry of Agriculture, Institute of Agricultural Resources and Regional Planning , Chinese Academy of Agricultural Sciences , Beijing 100081 , China., Zhai L; Key Laboratory of Non-point Source Pollution Control, Ministry of Agriculture, Institute of Agricultural Resources and Regional Planning , Chinese Academy of Agricultural Sciences , Beijing 100081 , China., Wang M; School of Materials Science and Engineering , Shijiazhuang Tiedao University , Shijiazhuang , Hebei Province 050043 , China., Du Y; School of Materials Science and Engineering , Shijiazhuang Tiedao University , Shijiazhuang , Hebei Province 050043 , China., Chen Y; School of Materials Science and Engineering , Shijiazhuang Tiedao University , Shijiazhuang , Hebei Province 050043 , China., Yang C; School of Materials Science and Engineering , Shijiazhuang Tiedao University , Shijiazhuang , Hebei Province 050043 , China., Xiao H; Department of Chemical Engineering , University of New Brunswick , Fredericton , NB E3B 5A3 Canada., Wang H; Key Laboratory of Non-point Source Pollution Control, Ministry of Agriculture, Institute of Agricultural Resources and Regional Planning , Chinese Academy of Agricultural Sciences , Beijing 100081 , China.

المصدر: Journal of agricultural and food chemistry [J Agric Food Chem] 2019 Jul 10; Vol. 67 (27), pp. 7616-7625. Date of Electronic Publication: 2019 Jun 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem

مواضيع طبية MeSH: Fertilizers*/analysis, Crops, Agricultural/*growth & development , Methylurea Compounds/*administration & dosage , Nitrogen/*administration & dosage, Agriculture/methods ; Delayed-Action Preparations ; Methylurea Compounds/chemical synthesis ; Methylurea Compounds/chemistry ; Spectroscopy, Fourier Transform Infrared ; Triticum/growth & development ; Zea mays/growth & development

المؤلفون: Shen Y; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute , Icahn School of Medicine at Mount Sinai , New York , New York 10029 , United States., McCorvy JD; Department of Pharmacology and National Institute of Mental Health Psychoactive Drug Screening Program, School of Medicine , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.; Department of Cell Biology, Neurobiology and Anatomy , Medical College of Wisconsin , Milwaukee , Wisconsin 53226 , United States., Martini ML; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute , Icahn School of Medicine at Mount Sinai , New York , New York 10029 , United States., Rodriguiz RM; Departments of Psychiatry and Behavioral Sciences, Cell Biology, and Neurobiology , Duke University Medical Center , Durham , North Carolina 27710 , United States., Pogorelov VM; Departments of Psychiatry and Behavioral Sciences, Cell Biology, and Neurobiology , Duke University Medical Center , Durham , North Carolina 27710 , United States., Ward KM; Worldwide Research and Development , Internal Medicine Research Unit, Pfizer , Cambridge , Massachusetts 02139 , United States., Wetsel WC; Departments of Psychiatry and Behavioral Sciences, Cell Biology, and Neurobiology , Duke University Medical Center , Durham , North Carolina 27710 , United States., Liu J; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute , Icahn School of Medicine at Mount Sinai , New York , New York 10029 , United States., Roth BL; Department of Pharmacology and National Institute of Mental Health Psychoactive Drug Screening Program, School of Medicine , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States., Jin J; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute , Icahn School of Medicine at Mount Sinai , New York , New York 10029 , United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2019 May 09; Vol. 62 (9), pp. 4755-4771. Date of Electronic Publication: 2019 Apr 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Dopamine Agonists/*pharmacology , GTP-Binding Protein alpha Subunits, Gi-Go/*metabolism , Isoquinolines/*pharmacology , Methylurea Compounds/*pharmacology , Receptors, Dopamine D2/*agonists, Animals ; Antipsychotic Agents/chemical synthesis ; Antipsychotic Agents/metabolism ; Antipsychotic Agents/pharmacology ; Dopamine Agonists/chemical synthesis ; Dopamine Agonists/metabolism ; Drug Design ; Drug Partial Agonism ; Female ; HEK293 Cells ; Humans ; Isoquinolines/chemical synthesis ; Isoquinolines/metabolism ; Locomotion/drug effects ; Male ; Methylurea Compounds/chemical synthesis ; Methylurea Compounds/metabolism ; Mice, Inbred C57BL ; Molecular Docking Simulation ; Molecular Structure ; Piperazines/chemistry ; Receptors, Dopamine D2/metabolism ; Signal Transduction/drug effects ; Structure-Activity Relationship ; beta-Arrestin 2/metabolism

المؤلفون: Grott SC; Environmental Engineering Post-Graduation Program, University of Blumenau, Blumenau, SC, Brazil., Israel N; Center for Studies in Aquatic Toxicology, CETAq/FURB, Brazil., Lima D; Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry, Department of Biochemistry, Federal University of Santa Catarina, UFSC, Florianópolis, SC, Brazil., Bitschinski D; Center for Studies in Aquatic Toxicology, CETAq/FURB, Brazil., Abel G; Center for Studies in Aquatic Toxicology, CETAq/FURB, Brazil., Alves TC; Environmental Engineering Post-Graduation Program, University of Blumenau, Blumenau, SC, Brazil., da Silva EB; Department of Natural Science, University of Blumenau, Blumenau, SC, Brazil., de Albuquerque CAC; Department of Natural Science, University of Blumenau, Blumenau, SC, Brazil., Mattos JJ; Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry, Department of Biochemistry, Federal University of Santa Catarina, UFSC, Florianópolis, SC, Brazil., Bainy ACD; Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry, Department of Biochemistry, Federal University of Santa Catarina, UFSC, Florianópolis, SC, Brazil., de Almeida EA; Environmental Engineering Post-Graduation Program, University of Blumenau, Blumenau, SC, Brazil. Electronic address: eduardoalves@furb.br.

المصدر: Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2022 Aug; Vol. 94, pp. 103910. Date of Electronic Publication: 2022 Jun 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9612020 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7077 (Electronic) Linking ISSN: 13826689 NLM ISO Abbreviation: Environ Toxicol Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Herbicides*/metabolism , Herbicides*/toxicity, Animals ; Larva ; Metamorphosis, Biological ; Methylurea Compounds ; Rana catesbeiana ; Temperature ; Thyroid Gland ; Thyroid Hormone Receptors beta

المؤلفون: Su M; College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding, China., Jia L; College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding, China.; Hebei Medical University, Shijiazhuang, China., Wu X; College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding, China., Sun H; College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding, China.

المصدر: Journal of the science of food and agriculture [J Sci Food Agric] 2018 Oct; Vol. 98 (13), pp. 4845-4853. Date of Electronic Publication: 2018 Jun 01.

نوع المنشور: Evaluation Study; Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 0376334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0010 (Electronic) Linking ISSN: 00225142 NLM ISO Abbreviation: J Sci Food Agric Subsets: MEDLINE

مواضيع طبية MeSH: Chromatography, High Pressure Liquid/*methods , Food Contamination/*analysis , Herbicides/*analysis , Methylurea Compounds/*analysis , Pesticide Residues/*analysis , Phenylurea Compounds/*analysis , Solid Phase Extraction/*methods , Vegetables/*chemistry, Herbicides/isolation & purification ; Methylurea Compounds/isolation & purification ; Pesticide Residues/isolation & purification ; Phenylurea Compounds/isolation & purification ; Polymers/chemical synthesis ; Polymers/chemistry ; Solid Phase Extraction/instrumentation

المؤلفون: de Lima EW; Department of Plant Production, College of Agricultural and Technological Sciences, São Paulo State University (UNESP), Dracena, SP, 17900-000, Brazil., Brunaldi BP; Department of Plant Production, College of Agricultural and Technological Sciences, São Paulo State University (UNESP), Dracena, SP, 17900-000, Brazil., Frias YA; Department of Plant Production, College of Agricultural and Technological Sciences, São Paulo State University (UNESP), Dracena, SP, 17900-000, Brazil., de Almeida Moreira BR; Department of Plant Production, College of Agricultural and Technological Sciences, São Paulo State University (UNESP), Dracena, SP, 17900-000, Brazil., da Silva Alves L; Department of Plant Production, College of Agricultural and Technological Sciences, São Paulo State University (UNESP), Dracena, SP, 17900-000, Brazil., Lopes PRM; Department of Plant Production, College of Agricultural and Technological Sciences, São Paulo State University (UNESP), Dracena, SP, 17900-000, Brazil. prm.lopes@unesp.br.

المصدر: Scientific reports [Sci Rep] 2022 Jun 02; Vol. 12 (1), pp. 9225. Date of Electronic Publication: 2022 Jun 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Microbiota* , Soil Pollutants*/metabolism, Bacteria/metabolism ; Carbon Dioxide ; Methylurea Compounds ; Soil

المؤلفون: Nishimura Y; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Esaki T; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Isshiki Y; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Okamoto N; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Furuta Y; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Kotake T; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Watanabe Y; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Ohta M; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Nakagawa T; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Noda H; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Shimizu M; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Saito H; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Tamura T; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan., Sato H; Research Division , Chugai Pharmaceutical Co., Ltd. , Komakado 1-135 , Gotemba , Shizuoka 412-8513 , Japan.

المصدر: Journal of medicinal chemistry [J Med Chem] 2018 Jul 26; Vol. 61 (14), pp. 5949-5962. Date of Electronic Publication: 2018 Jul 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery*, Hypoparathyroidism/*drug therapy , Methylurea Compounds/*therapeutic use , Receptor, Parathyroid Hormone, Type 1/*agonists , Small Molecule Libraries/*pharmacokinetics , Small Molecule Libraries/*pharmacology , Sulfones/*therapeutic use , Urea/*pharmacokinetics , Urea/*pharmacology, Administration, Oral ; Biological Availability ; Cell Line ; Humans ; Methylurea Compounds/administration & dosage ; Methylurea Compounds/pharmacology ; Small Molecule Libraries/administration & dosage ; Small Molecule Libraries/therapeutic use ; Sulfones/administration & dosage ; Sulfones/pharmacology ; Urea/administration & dosage ; Urea/therapeutic use

المؤلفون: Patil-Sen Y; School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK., Dennison SR; School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK., Snape TJ; School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK. Electronic address: tjsnape@uclan.ac.uk.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2016 Sep 15; Vol. 24 (18), pp. 4241-4245. Date of Electronic Publication: 2016 Jul 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents/*pharmacology , Cell Membrane/*drug effects , Methylurea Compounds/*pharmacology , Phenylurea Compounds/*pharmacology , Surface-Active Agents/*pharmacology, Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Cell Membrane/metabolism ; Cell Membrane Permeability ; Escherichia coli/drug effects ; Methylurea Compounds/chemical synthesis ; Methylurea Compounds/chemistry ; Molecular Conformation ; Molecular Structure ; Phenylurea Compounds/chemical synthesis ; Phenylurea Compounds/chemistry ; Polymyxin B/pharmacology ; Staphylococcus aureus/drug effects ; Surface-Active Agents/chemical synthesis ; Surface-Active Agents/chemistry

المؤلفون: Kobayashi S; a Graduate School of Biosphere Science , Hiroshima University , Higashi-Hiroshima , Japan., Fujii S; a Graduate School of Biosphere Science , Hiroshima University , Higashi-Hiroshima , Japan., Koga A; a Graduate School of Biosphere Science , Hiroshima University , Higashi-Hiroshima , Japan., Wakai S; b Graduate School of Science Technology and Innovation , Kobe University , Kobe , Japan., Matubayasi N; c Graduate School of Engineering Science , Osaka University , Osaka , Japan.; d Elements Strategy Initiative for Catalysts and Batteries , Kyoto University , Kyoto , Japan., Sambongi Y; a Graduate School of Biosphere Science , Hiroshima University , Higashi-Hiroshima , Japan.

المصدر: Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2017 Jul; Vol. 81 (7), pp. 1274-1278. Date of Electronic Publication: 2017 Mar 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9205717 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-6947 (Electronic) Linking ISSN: 09168451 NLM ISO Abbreviation: Biosci Biotechnol Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*chemistry , Cytochrome c Group/*chemistry , Methylurea Compounds/*chemistry , Pseudomonas aeruginosa/*chemistry , Urea/*analogs & derivatives , Urea/*chemistry, Bacterial Proteins/isolation & purification ; Cytochrome c Group/isolation & purification ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Gene Expression ; Methylurea Compounds/pharmacology ; Protein Denaturation/drug effects ; Pseudomonas aeruginosa/enzymology ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification ; Structure-Activity Relationship ; Thermodynamics ; Urea/pharmacology