المؤلفون: Delgado-Martin, C, Meyer, LK, Huang, BJ, Shimano, KA, Zinter, MS, Nguyen, JV, Smith, GA, Taunton, J, Winter, SS, Roderick, JR, Kelliher, MA, Horton, TM, Wood, BL, Teachey, DT, Hermiston, ML

المصدر: Leukemia. 31(12)

مصطلحات موضوعية: Cell Line, Tumor, Animals, Humans, Mice, Disease Models, Animal, Dexamethasone, Proto-Oncogene Proteins c-bcl-2, Antineoplastic Agents, Interleukin-7, Glucocorticoids, Xenograft Model Antitumor Assays, Signal Transduction, Drug Resistance, Neoplasm, STAT Transcription Factors, Janus Kinases, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Bcl-2-Like Protein 11, Janus Kinase Inhibitors, Pediatric Cancer, Cancer, Hematology, Pediatric, Childhood Leukemia, Clinical Research, Rare Diseases, 5.1 Pharmaceuticals, Immunology, Clinical Sciences, Oncology and Carcinogenesis

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المؤلفون: Meyer LK; University of Washington., Nichols KE; St. Jude Children's Research Hospital.

المصدر: Blood [Blood] 2024 Aug 22; Vol. 144 (8), pp. 802-804.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: T-Lymphocytes, Cytotoxic*/immunology , Lymphohistiocytosis, Hemophagocytic*/diagnosis , Lymphohistiocytosis, Hemophagocytic*/immunology, Humans

المؤلفون: Keenan C; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN., Albeituni S; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN., Oak N; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN., Stroh A; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN., Tillman HS; Department of Comparative Pathology Core, St. Jude Children's Research Hospital, Memphis, TN., Wang Y; Preclinical PK Shared Resource, St. Jude Children's Research Hospital, Memphis, TN., Freeman BB 3rd; Preclinical PK Shared Resource, St. Jude Children's Research Hospital, Memphis, TN., Alemán-Arteaga S; Experimental Therapeutics & Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas/Universidad de Salamanca, Salamanca, Spain., Meyer LK; Department of Pediatrics, University of Washington, Seattle, WA., Woods R; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN., Verbist KC; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN., Zhou Y; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN., Cheng C; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN., Nichols KE; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN.

المصدر: Blood [Blood] 2024 Jun 06; Vol. 143 (23), pp. 2386-2400.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Nitriles* , Pyrimidines*/pharmacology , Lymphohistiocytosis, Hemophagocytic*/drug therapy , Lymphohistiocytosis, Hemophagocytic*/chemically induced , Lymphohistiocytosis, Hemophagocytic*/pathology , Pyrazoles*/pharmacology , Pyrazoles*/therapeutic use , Disease Models, Animal*, Animals ; Mice ; Janus Kinase 1/antagonists & inhibitors ; Janus Kinase 1/metabolism ; Janus Kinase 1/genetics ; Pyrroles/pharmacology ; Pyrroles/therapeutic use ; Janus Kinase 2/antagonists & inhibitors ; Janus Kinase 2/genetics ; Janus Kinase 2/metabolism ; Mice, Inbred C57BL ; Sulfonamides/pharmacology ; Sulfonamides/therapeutic use ; STAT1 Transcription Factor/metabolism ; STAT1 Transcription Factor/genetics ; Janus Kinase Inhibitors/pharmacology ; Janus Kinase Inhibitors/therapeutic use ; Piperidines/pharmacology ; Humans ; Benzenesulfonamides ; Bridged-Ring Compounds ; Pyrrolidines

المؤلفون: Meyer LK; Department of Pediatrics, University of Washington, Seattle, Washington, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, California, USA., Huang I; Department of Pathology and Laboratory Medicine, University of California San Francisco, San Francisco, California, USA., Huang BJ; Department of Pediatrics, University of California San Francisco, San Francisco, California, USA., Chung JH; Department of Pediatrics, University of California Davis, Davis, California, USA., Pawar A; Department of Pediatrics, University of California Davis, Davis, California, USA., Hermiston ML; Department of Pediatrics, University of California San Francisco, San Francisco, California, USA., Loh ML; Department of Pediatrics, University of Washington, Seattle, Washington, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, California, USA., Ohgami RS; Department of Pathology and Laboratory Medicine, University of California San Francisco, San Francisco, California, USA.; Department of Pathology, University of Utah, Salt Lake City, Utah, USA., Ruiz-Cordero R; Department of Pathology and Laboratory Medicine, University of California San Francisco, San Francisco, California, USA.; Department of Pathology and Laboratory Medicine, University of Miami, Miami, Florida, USA., Bhargava P; Department of Pathology and Laboratory Medicine, University of California San Francisco, San Francisco, California, USA., Marinoff AE; Department of Pediatrics, University of California San Francisco, San Francisco, California, USA.

المصدر: Pediatric blood & cancer [Pediatr Blood Cancer] 2023 Dec; Vol. 70 (12), pp. e30677. Date of Electronic Publication: 2023 Sep 13.

نوع المنشور: Letter

بيانات الدورية: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE

المؤلفون: Meyer LK; University of Washington., Nichols KE; St. Jude Children's Research Hospital.

المصدر: Blood [Blood] 2023 Nov 16; Vol. 142 (20), pp. 1679-1681.

نوع المنشور: Editorial; Comment

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction* , Histiocytosis*, Humans ; Inflammation

المؤلفون: Levinson AL; Department of Pediatrics, University of California, San Francisco, CA., Tjoa K; Department of Pediatrics, University of California, San Francisco, CA., Huang B; Department of Pediatrics, University of California, San Francisco, CA., Meyer LK; Department of Pediatrics, University of California, San Francisco, CA., Kim MO; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA., Brady SW; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN., Zhang J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN., Shannon K; Department of Pediatrics, University of California, San Francisco, CA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA., Wandler AM; Department of Pediatrics, University of California, San Francisco, CA.

المصدر: Blood advances [Blood Adv] 2023 Jul 25; Vol. 7 (14), pp. 3479-3484.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/genetics , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/metabolism , Precursor Cell Lymphoblastic Leukemia-Lymphoma*/metabolism, Child ; Humans ; Mice ; Animals ; Glucocorticoids/pharmacology ; Glucocorticoids/therapeutic use ; Dexamethasone/pharmacology ; Receptors, Glucocorticoid/genetics ; Recurrence ; Repressor Proteins

المؤلفون: Meyer LK; University of Washington., Nichols KE; St. Jude Children's Research Hospital.

المصدر: Blood [Blood] 2023 May 11; Vol. 141 (19), pp. 2288-2290.

نوع المنشور: Editorial; Comment

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Lymphohistiocytosis, Hemophagocytic*/genetics, Humans ; Uncertainty ; Genotype ; Phenotype

المؤلفون: Steen EA; University of California, San Diego, CA, United States., Nichols KE; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, United States., Meyer LK; Department of Pediatrics, University of Washington, Seattle, WA, United States.

المصدر: Frontiers in immunology [Front Immunol] 2023 Mar 09; Vol. 14, pp. 1147603. Date of Electronic Publication: 2023 Mar 09 (Print Publication: 2023).

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Lymphohistiocytosis, Hemophagocytic*, Humans ; Animals ; Mice ; CD8-Positive T-Lymphocytes ; Killer Cells, Natural ; Cytotoxicity, Immunologic ; Cytokines/metabolism

المؤلفون: Meyer LK; Department of Pediatrics, University of California, San Francisco, California, USA., Delgado-Martin C; Department of Pediatrics, University of California, San Francisco, California, USA., Sharp PP; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA., Huang BJ; Department of Pediatrics, University of California, San Francisco, California, USA., McMinn D; Kezar Life Sciences, South San Francisco, California, USA., Vincent TL; Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Ryan T; Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Horton TM; Texas Children's Hospital, Houston, Texas, USA., Wood BL; Children's Hospital Los Angeles, Los Angeles, California, USA., Teachey DT; Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Taunton J; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA.; Kezar Life Sciences, South San Francisco, California, USA., Kirk CJ; Kezar Life Sciences, South San Francisco, California, USA., Hermiston ML; Department of Pediatrics, University of California, San Francisco, California, USA.

المصدر: British journal of haematology [Br J Haematol] 2022 Jul; Vol. 198 (1), pp. 137-141. Date of Electronic Publication: 2022 Apr 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE

مواضيع طبية MeSH: Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/metabolism , SEC Translocation Channels*/metabolism, Cytokines/metabolism ; Dexamethasone/pharmacology ; Glucocorticoids/pharmacology ; Humans ; Interleukin-7 ; Metabolism, Inborn Errors ; Receptors, Glucocorticoid/deficiency ; T-Lymphocytes/metabolism

SCR Disease Name: Glucocorticoid Receptor Deficiency