المؤلفون: Digles D, Zdrazil B, Jm, Neefs, Van Vlijmen H, Herhaus C, Caracoti A, Brea J, Roibás B, Mi, Loza, Queralt-Rosinach N, Li, Furlong, Anna Gaulton, Bartek L, Senger S, Chichester C, Engkvist O, Ct, Evelo, Ni, Franklin, Marren D, Gf, Ecker

المصدر: Europe PubMed Central

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0726c399cf1eb3721965f060c6d6ce51
http://europepmc.org/abstract/med/27774140

المؤلفون: Jf, López-Giménez, Villazón M, Jose Brea, Mi, Loza, Jm, Palacios, Mengod G, Mt, Vilaró

المصدر: Europe PubMed Central

مصطلحات موضوعية: Binding Sites, Protein Conformation, Inositol Phosphates, Brain, CHO Cells, Transfection, Tritium, Recombinant Proteins, Serotonin Receptor Agonists, Fluorobenzenes, Piperidines, Cricetinae, Receptors, Serotonin, Animals, Autoradiography, Humans, Receptor, Serotonin, 5-HT2A, Serotonin Antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::919fe73c25f050e95ab2d558005f7536
http://europepmc.org/abstract/med/11562430

المؤلفون: Borrajo ML; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University de Santiago de Compostela, Av. Barcelona s/n, Campus Vida, Santiago de Compostela, 15782, Spain.; Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain.; IDIS Research Institute, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain., Lou G; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University de Santiago de Compostela, Av. Barcelona s/n, Campus Vida, Santiago de Compostela, 15782, Spain.; IDIS Research Institute, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain., Anthiya S; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University de Santiago de Compostela, Av. Barcelona s/n, Campus Vida, Santiago de Compostela, 15782, Spain.; IDIS Research Institute, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain., Lapuhs P; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University de Santiago de Compostela, Av. Barcelona s/n, Campus Vida, Santiago de Compostela, 15782, Spain.; IDIS Research Institute, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain., Álvarez DM; Biofarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University of Santiago de Compostela, Av. Barcelona s/n, Campus Vida, Santiago de Compostela, 15782, Spain., Tobío A; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University de Santiago de Compostela, Av. Barcelona s/n, Campus Vida, Santiago de Compostela, 15782, Spain.; Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain.; IDIS Research Institute, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain., Loza MI; Biofarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University of Santiago de Compostela, Av. Barcelona s/n, Campus Vida, Santiago de Compostela, 15782, Spain., Vidal A; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University de Santiago de Compostela, Av. Barcelona s/n, Campus Vida, Santiago de Compostela, 15782, Spain.; IDIS Research Institute, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain., Alonso MJ; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University de Santiago de Compostela, Av. Barcelona s/n, Campus Vida, Santiago de Compostela, 15782, Spain. mariaj.alonso@usc.es.; Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain. mariaj.alonso@usc.es.; IDIS Research Institute, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain. mariaj.alonso@usc.es.

المصدر: Drug delivery and translational research [Drug Deliv Transl Res] 2024 Aug; Vol. 14 (8), pp. 2046-2061. Date of Electronic Publication: 2024 May 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101540061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2190-3948 (Electronic) Linking ISSN: 2190393X NLM ISO Abbreviation: Drug Deliv Transl Res Subsets: MEDLINE

مواضيع طبية MeSH: Administration, Intranasal* , Nanocapsules*/chemistry , mRNA Vaccines* , Emulsions* , COVID-19 Vaccines*/administration & dosage , COVID-19 Vaccines*/immunology, Animals ; Mice ; COVID-19/prevention & control ; Nanoparticles/administration & dosage ; Nanoparticles/chemistry ; Humans ; SARS-CoV-2/immunology ; Female ; Quaternary Ammonium Compounds/chemistry ; Mice, Inbred BALB C ; Fatty Acids, Monounsaturated/chemistry ; RNA, Messenger/administration & dosage ; Drug Carriers/chemistry ; Drug Carriers/administration & dosage

المؤلفون: Intranuovo F; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari ALDO MORO, via Orabona 4, 70125 Bari, Italy., Majellaro M; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, 15782 Santiago, Spain.; Departamento de Quimica Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain., Mastropasqua F; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari ALDO MORO, via Orabona 4, 70125 Bari, Italy., Delre P; Institute of Crystallography, National Research Council of Italy, Via Amendola, 122/o, 70126 Bari, Italy., Abatematteo FS; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari ALDO MORO, via Orabona 4, 70125 Bari, Italy., Mangiatordi GF; Institute of Crystallography, National Research Council of Italy, Via Amendola, 122/o, 70126 Bari, Italy., Stefanachi A; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari ALDO MORO, via Orabona 4, 70125 Bari, Italy., Brea J; Innopharma Screening Platform, BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.; Department of Pharmacology, Pharmacy and Pharmaceutical Technology. School of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain., Loza MI; Innopharma Screening Platform, BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.; Department of Pharmacology, Pharmacy and Pharmaceutical Technology. School of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain., Riganti C; Dipartimento di Oncologia, Università degli Studi di Torino, 10124 Torino, Italy., Ligresti A; National Research Council of Italy, Institute of Biomolecular Chemistry, 80078 Pozzuoli (NA), Italy., Kumar P; National Research Council of Italy, Institute of Biomolecular Chemistry, 80078 Pozzuoli (NA), Italy., Esposito D; National Research Council of Italy, Institute of Biomolecular Chemistry, 80078 Pozzuoli (NA), Italy., Cristino L; National Research Council of Italy, Institute of Biomolecular Chemistry, 80078 Pozzuoli (NA), Italy., Nicois A; National Research Council of Italy, Institute of Biomolecular Chemistry, 80078 Pozzuoli (NA), Italy., González L; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, 15782 Santiago, Spain.; Departamento de Quimica Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain., Perrone MG; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari ALDO MORO, via Orabona 4, 70125 Bari, Italy., Colabufo NA; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari ALDO MORO, via Orabona 4, 70125 Bari, Italy., Sotelo E; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, 15782 Santiago, Spain.; Departamento de Quimica Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain., Abate C; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari ALDO MORO, via Orabona 4, 70125 Bari, Italy., Contino M; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari ALDO MORO, via Orabona 4, 70125 Bari, Italy.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Jul 11; Vol. 67 (13), pp. 11003-11023. Date of Electronic Publication: 2024 Jun 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Receptor, Cannabinoid, CB2*/metabolism , Fluorescent Dyes*/chemistry , Fluorescent Dyes*/chemical synthesis , Microglia*/metabolism, Humans ; Animals ; Quinolines/chemistry ; Quinolines/chemical synthesis ; Adamantane/analogs & derivatives ; Adamantane/chemistry ; Adamantane/chemical synthesis ; Adamantane/pharmacology ; Ligands ; Structure-Activity Relationship

المؤلفون: Kossatz E; Integrative Pharmacology and Systems Neuroscience Research Group, Hospital del Mar Research Institute, Barcelona, Spain., Diez-Alarcia R; Department of Pharmacology, University of the Basque Country/Euskal Herriko Unibertsitatea, Leioa, Bizkaia, Spain.; Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, Madrid, Spain.; Instituto de Investigación Sanitaria Biobizkaia, Barakaldo, Bizkaia, Spain., Gaitonde SA; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, Québec, H3T 1J4, Canada., Ramon-Duaso C; Cell-type mechanisms in normal and pathological behaviour Research Group, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain., Stepniewski TM; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Research Institute, Barcelona, Spain.; InterAx Biotech AG, PARK InnovAARE, 5234, Villigen, Switzerland., Aranda-Garcia D; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Research Institute, Barcelona, Spain.; Department of Medicine and Life Sciences, Pompeu Fabra University, Barcelona, Spain., Muneta-Arrate I; Department of Pharmacology, University of the Basque Country/Euskal Herriko Unibertsitatea, Leioa, Bizkaia, Spain.; Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, Madrid, Spain., Tepaz E; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, Québec, H3T 1J4, Canada., Saen-Oon S; NBD NOSTRUM BIODISCOVERY, Av. de Josep Tarradellas, 8-10, 3-2, 08029, Barcelona, Spain., Soliva R; NBD NOSTRUM BIODISCOVERY, Av. de Josep Tarradellas, 8-10, 3-2, 08029, Barcelona, Spain., Shahraki A; Pharmaceutical Chemistry, University of Marburg, Marbacher Weg 8, Marburg, 35037, Germany., Moreira D; Innopharma Drug Screening and Pharmacogenomics Platform. BioFarma research group. Center for Research in Molecular Medicine and Chronic Diseases (CiMUS). Department of Pharmacology, Pharmacy and Pharmaceutical Technology, University of Santiago de Compostela, Santiago de Compostela, Spain.; Health Research Institute of Santiago de Compostela (IDIS), University Hospital of Santiago de Compostela (SERGAS), Trav. Choupana s/n, 15706, Santiago de Compostela, Spain., Brea J; Pharmaceutical Chemistry, University of Marburg, Marbacher Weg 8, Marburg, 35037, Germany.; Innopharma Drug Screening and Pharmacogenomics Platform. BioFarma research group. Center for Research in Molecular Medicine and Chronic Diseases (CiMUS). Department of Pharmacology, Pharmacy and Pharmaceutical Technology, University of Santiago de Compostela, Santiago de Compostela, Spain., Loza MI; Innopharma Drug Screening and Pharmacogenomics Platform. BioFarma research group. Center for Research in Molecular Medicine and Chronic Diseases (CiMUS). Department of Pharmacology, Pharmacy and Pharmaceutical Technology, University of Santiago de Compostela, Santiago de Compostela, Spain.; Health Research Institute of Santiago de Compostela (IDIS), University Hospital of Santiago de Compostela (SERGAS), Trav. Choupana s/n, 15706, Santiago de Compostela, Spain., de la Torre R; Integrative Pharmacology and Systems Neuroscience Research Group, Hospital del Mar Research Institute, Barcelona, Spain., Kolb P; Pharmaceutical Chemistry, University of Marburg, Marbacher Weg 8, Marburg, 35037, Germany., Bouvier M; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, Québec, H3T 1J4, Canada., Meana JJ; Department of Pharmacology, University of the Basque Country/Euskal Herriko Unibertsitatea, Leioa, Bizkaia, Spain.; Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, Madrid, Spain.; Instituto de Investigación Sanitaria Biobizkaia, Barakaldo, Bizkaia, Spain., Robledo P; Integrative Pharmacology and Systems Neuroscience Research Group, Hospital del Mar Research Institute, Barcelona, Spain. probledo@imim.es., Selent J; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Research Institute, Barcelona, Spain. jana.selent@upf.edu.; Department of Medicine and Life Sciences, Pompeu Fabra University, Barcelona, Spain. jana.selent@upf.edu.

المصدر: Nature communications [Nat Commun] 2024 May 29; Vol. 15 (1), pp. 4307. Date of Electronic Publication: 2024 May 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Memory Disorders*/metabolism , Psychotic Disorders*/metabolism , Psychotic Disorders*/drug therapy , Receptor, Serotonin, 5-HT2A*/metabolism , Serotonin*/metabolism, Animals ; Female ; Humans ; Male ; Mice ; Brain/metabolism ; GTP-Binding Protein alpha Subunits, Gq-G11/metabolism ; GTP-Binding Protein alpha Subunits, Gq-G11/genetics ; HEK293 Cells ; Schizophrenia/metabolism ; Signal Transduction

المؤلفون: Areias F; Centre of Chemistry of University of Minho (CQUM), Campus de Gualtar, Universidade do Minho, 4710-057 Braga, Portugal.; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, Avda de Barcelona, E-15782 Santiago de Compostela, Spain.; School of Chemical Sciences & Engineering, Yachay Tech University, Yachay City of Knowledge, Urcuqui 100119, Ecuador., Correia C; Centre of Chemistry of University of Minho (CQUM), Campus de Gualtar, Universidade do Minho, 4710-057 Braga, Portugal., Rocha A; Centre of Chemistry of University of Minho (CQUM), Campus de Gualtar, Universidade do Minho, 4710-057 Braga, Portugal., Teixeira S; Centre of Chemistry of University of Minho (CQUM), Campus de Gualtar, Universidade do Minho, 4710-057 Braga, Portugal., Castro M; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, Avda de Barcelona, E-15782 Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Travesía da Choupana s/n, E-15706 Santiago de Compostela, Spain., Brea J; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, Avda de Barcelona, E-15782 Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Travesía da Choupana s/n, E-15706 Santiago de Compostela, Spain., Hu H; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, SE-75124 Uppsala, Sweden., Carlsson J; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, SE-75124 Uppsala, Sweden., Loza MI; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, Avda de Barcelona, E-15782 Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Travesía da Choupana s/n, E-15706 Santiago de Compostela, Spain., Proença MF; Centre of Chemistry of University of Minho (CQUM), Campus de Gualtar, Universidade do Minho, 4710-057 Braga, Portugal., Carvalho MA; Centre of Chemistry of University of Minho (CQUM), Campus de Gualtar, Universidade do Minho, 4710-057 Braga, Portugal.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2024 May 28; Vol. 29 (11). Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Purinergic P1 Receptor Antagonists*/pharmacology , Purinergic P1 Receptor Antagonists*/chemistry, Humans ; Structure-Activity Relationship ; Receptors, Purinergic P1/metabolism ; Molecular Structure ; Adenine/analogs & derivatives ; Adenine/chemistry ; Adenine/pharmacology ; Morpholines/chemistry ; Morpholines/pharmacology ; Purines/chemistry ; Purines/pharmacology ; Purines/chemical synthesis ; CHO Cells

المؤلفون: Rama-Garda R; Discovery Chemistry Research & Technologies, Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain.; BioFarma, Universidad de Santiago de Compostela (USC), Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CIMUS), A Coruña, Spain., Domínguez E; Genomic Medicine, Universidad de Santiago de Compostela (USC), Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CIMUS), A Coruña, Spain., Loza MI; BioFarma, Universidad de Santiago de Compostela (USC), Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CIMUS), A Coruña, Spain., Lallena MJ; Discovery Chemistry Research & Technologies, Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain., de Blas J; Discovery Chemistry Research & Technologies, Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain., Toledo MÁ; Discovery Chemistry Research & Technologies, Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain., Haro R; Discovery Chemistry Research & Technologies, Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain.

المصدر: Assay and drug development technologies [Assay Drug Dev Technol] 2024 May-Jun; Vol. 22 (4), pp. 192-202. Date of Electronic Publication: 2024 Apr 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101151468 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8127 (Electronic) Linking ISSN: 1540658X NLM ISO Abbreviation: Assay Drug Dev Technol Subsets: MEDLINE

مواضيع طبية MeSH: High-Throughput Screening Assays* , DNA*/chemistry, Immobilized Proteins/chemistry ; Gene Library ; Ligands

المؤلفون: Brea J; Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CiMUS), School of Pharmacy, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Health Research Institute of Santiago de Compostela (IDIS), University Hospital of Santiago de Compostela (SERGAS), Trav. Choupana s/n, Santiago de Compostela 15706, Spain. Electronic address: pepo.brea@usc.es., Varela MJ; Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CiMUS), School of Pharmacy, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain., Daudey GA; Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CiMUS), School of Pharmacy, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain., Loza MI; Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CiMUS), School of Pharmacy, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Health Research Institute of Santiago de Compostela (IDIS), University Hospital of Santiago de Compostela (SERGAS), Trav. Choupana s/n, Santiago de Compostela 15706, Spain. Electronic address: mabel.loza@usc.es.

المصدر: SLAS discovery : advancing life sciences R & D [SLAS Discov] 2024 Apr; Vol. 29 (3), pp. 100149. Date of Electronic Publication: 2024 Mar 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101697563 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2472-5560 (Electronic) Linking ISSN: 24725552 NLM ISO Abbreviation: SLAS Discov Subsets: MEDLINE

مواضيع طبية MeSH: Solubility* , High-Throughput Screening Assays*/methods , Small Molecule Libraries*/chemistry , Water*/chemistry, Nephelometry and Turbidimetry/methods

المؤلفون: Martínez AL; BioFarma Research Group, Centro Singular de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain; Instituto de Investigacións Sanitarias de Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Brea J; BioFarma Research Group, Centro Singular de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain; Instituto de Investigacións Sanitarias de Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela, Spain., López D; BioFarma Research Group, Centro Singular de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain; Instituto de Investigacións Sanitarias de Santiago de Compostela (IDIS), Santiago de Compostela, Spain., Cosme N; BioFarma Research Group, Centro Singular de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain; Instituto de Investigacións Sanitarias de Santiago de Compostela (IDIS), Santiago de Compostela, Spain., Barro M; BioFarma Research Group, Centro Singular de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain; Instituto de Investigacións Sanitarias de Santiago de Compostela (IDIS), Santiago de Compostela, Spain., Monroy X; WeLab Barcelona, Parc Científic de Barcelona, Barcelona, Spain., Burgueño J; WeLab Barcelona, Parc Científic de Barcelona, Barcelona, Spain., Merlos M; WeLab Barcelona, Parc Científic de Barcelona, Barcelona, Spain., Loza MI; BioFarma Research Group, Centro Singular de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain; Instituto de Investigacións Sanitarias de Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela, Spain. Electronic address: mabel.loza@usc.es.

المصدر: Pharmacological research [Pharmacol Res] 2024 Apr; Vol. 202, pp. 107111. Date of Electronic Publication: 2024 Feb 19.

نوع المنشور: Review; Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-1186 (Electronic) Linking ISSN: 10436618 NLM ISO Abbreviation: Pharmacol Res Subsets: MEDLINE

مواضيع طبية MeSH: Neuralgia*/drug therapy, Humans ; Brain

المؤلفون: Prieto-Díaz R; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain., Fojo-Carballo H; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain., Majellaro M; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain. Electronic address: ma.majellaro@usc.es., Tandarić T; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Biomedical Centre, Uppsala 75124, Sweden., Azuaje J; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain., Brea J; Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CiMUS), Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain. Electronic address: pepo.brea@usc.es., Loza MI; Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CiMUS), Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain., Barbazán J; Grupo de Oncología Médica Traslacional (ONCOMET), Instituto de Investigación Sanitaria, Santiago de Compostela (IDIS), Hospital Universitario de Santiago de Compostela (SERGAS), Santiago de Compostela 15706, Spain. Electronic address: jorge.barbazan.garcia@sergas.es., Salort G; Unidad de Farmacología, Departamento de Patología y Terapéutica Experimental, Facultad de Medicina y Ciencias de la Salud, Instituto de Neurociencia, Universitat de Barcelona, L'Hospitalet de Llobregat 08907, Spain; Neuropharmacology and Pain Group, Neuroscience Program, Institut d'Investigació Biomèdica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat 08907, Spain; Laboratorio de Neurofarmacología, Institut Universitari d'Investigació en Ciències de la Salut (IUNICS), Institut d'investigació Sanitària Illes Balears (IdISBa), University of the Balearic Islands, Palma de Mallorca 07122, Spain., Chotalia M; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain., Rodríguez-Pampín I; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain., Mallo-Abreu A; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain., Rita Paleo M; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain., García-Mera X; Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain., Ciruela F; Unidad de Farmacología, Departamento de Patología y Terapéutica Experimental, Facultad de Medicina y Ciencias de la Salud, Instituto de Neurociencia, Universitat de Barcelona, L'Hospitalet de Llobregat 08907, Spain; Neuropharmacology and Pain Group, Neuroscience Program, Institut d'Investigació Biomèdica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat 08907, Spain., Gutiérrez-de-Terán H; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Biomedical Centre, Uppsala 75124, Sweden. Electronic address: hugo.gutierrez@icm.uu.se., Sotelo E; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain; Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain. Electronic address: e.sotelo@usc.es.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Apr; Vol. 173, pp. 116345. Date of Electronic Publication: 2024 Mar 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Colorectal Neoplasms*/drug therapy, Humans ; Purinergic P1 Receptor Antagonists ; Receptor, Adenosine A2B/metabolism ; Adenosine A2 Receptor Antagonists/pharmacology ; Structure-Activity Relationship