المؤلفون: Ilango Balakrishnan, Etienne Danis, Angela Pierce, Krishna Madhavan, Dong Wang, Nathan Dahl, Bridget Sanford, Diane K. Birks, Nate Davidson, Dennis S. Metselaar, Michaël Hananja Meel, Rakeb Lemma, Andrew Donson, Trinka Vijmasi, Hiroaki Katagi, Ismail Sola, Susan Fosmire, Irina Alimova, Jenna Steiner, Ahmed Gilani, Esther Hulleman, Natalie J. Serkova, Rintaro Hashizume, Cynthia Hawkins, Angel M. Carcaboso, Nalin Gupta, Michelle Monje, Nada Jabado, Kenneth Jones, Nicholas Foreman, Adam Green, Rajeev Vibhakar, Sujatha Venkataraman

المصدر: Cell Reports, Vol 33, Iss 3, Pp 108286- (2020)

مصطلحات موضوعية: DIPG, RNAi screen, BMI1, PTC 028, BH3 mimetics, senescence, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124720312754; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/df550ba18a7344fb83017de0c06084bc

المؤلفون: Gertjan J.L. Kaspers, Bente Benedict, Dennis S. Metselaar, Esther Hulleman, Michaël Hananja Meel, Piotr Waranecki, Jan Koster

المساهمون: Pediatric surgery, CCA - Cancer biology and immunology, Oncogenomics, AII - Inflammatory diseases

المصدر: EBioMedicine, Vol 50, Iss, Pp 81-92 (2019)
EBioMedicine, 50, 81-92. Elsevier BV
Metselaar, D S, Meel, M H, Benedict, B, Waranecki, P, Koster, J, Kaspers, G J L & Hulleman, E 2019, ' Celastrol-induced degradation of FANCD2 sensitizes pediatric high-grade gliomas to the DNA-crosslinking agent carboplatin ', EBioMedicine, vol. 50, pp. 81-92 . https://doi.org/10.1016/j.ebiom.2019.10.062
EBioMedicine

مصطلحات موضوعية: Male, 0301 basic medicine, Research paper, lcsh:Medicine, Carboplatin, Mice, chemistry.chemical_compound, 0302 clinical medicine, hemic and lymphatic diseases, DNA-crosslinking, Child, Gene knockdown, lcsh:R5-920, Fanconi Anemia Complementation Group D2 Protein, Glioma, General Medicine, Celastrol, Cross-Linking Reagents, Child, Preschool, 030220 oncology & carcinogenesis, Female, Pentacyclic Triterpenes, lcsh:Medicine (General), Adolescent, Combination therapy, Cell Survival, DNA damage, Preclinical therapy development, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, In vivo, Cell Line, Tumor, FANCD2, medicine, Animals, Humans, business.industry, lcsh:R, medicine.disease, Xenograft Model Antitumor Assays, Triterpenes, Disease Models, Animal, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, Pediatric high-grade glioma, Proteolysis, Cancer research, Neoplasm Grading, business, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9daa52b3f7d2533ca01f7e5e92587e
http://www.sciencedirect.com/science/article/pii/S235239641930739X

المؤلفون: Gertjan J.L. Kaspers, Esther Hulleman, Michaël Hananja Meel

المساهمون: Pediatric surgery, CCA - Cancer biology and immunology

المصدر: Drug Resistance Updates, 44, 15-25. Churchill Livingstone
Meel, M H, Kaspers, G J L & Hulleman, E 2019, ' Preclinical therapeutic targets in diffuse midline glioma ', Drug Resistance Updates, vol. 44, pp. 15-25 . https://doi.org/10.1016/j.drup.2019.06.001

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, Intrinsic resistance, Antineoplastic Agents, Histone Deacetylases, Epigenesis, Genetic, Targeted therapy, Histones, 03 medical and health sciences, 0302 clinical medicine, Mesencephalon, Glioma, Internal medicine, medicine, Humans, Effective treatment, Pharmacology (medical), Molecular Targeted Therapy, Treatment resistance, Child, Pharmacology, Brain Neoplasms, business.industry, Cellular pathways, Cell Cycle Checkpoints, medicine.disease, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Infectious Diseases, Blood-Brain Barrier, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, business, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490284ecece9cab4dceb8c00e5615fb4
https://doi.org/10.1016/j.drup.2019.06.001