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1دورية أكاديمية
المؤلفون: Gergely Tóth, Shyra J Gardai, Wagner Zago, Carlos W Bertoncini, Nunilo Cremades, Susan L Roy, Mitali A Tambe, Jean-Christophe Rochet, Celine Galvagnion, Gaia Skibinski, Steven Finkbeiner, Michael Bova, Karin Regnstrom, San-San Chiou, Jennifer Johnston, Kari Callaway, John P Anderson, Michael F Jobling, Alexander K Buell, Ted A Yednock, Tuomas P J Knowles, Michele Vendruscolo, John Christodoulou, Christopher M Dobson, Dale Schenk, Lisa McConlogue
المصدر: PLoS ONE, Vol 9, Iss 2, p e87133 (2014)
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Karin Regnström, Jiangli Yan, Lan Nguyen, Kari Callaway, Yanli Yang, Linnea Diep, Weimei Xing, Anirban Adhikari, Paul Beroza, Roy K Hom, Brigit Riley, Don Rudolph, Michael F Jobling, Jeanne Baker, Jennifer Johnston, Andrei Konradi, Michael P Bova, Dean R Artis
المصدر: PLoS ONE, Vol 8, Iss 7, p e66879 (2013)
وصف الملف: electronic resource
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3
المؤلفون: Amandine Berthet, Daniel Schwizer, David A. Agard, Eliezer Masliah, Mariano C. Tabios, Thomas Neumann, Ted Yednock, Gergely Tóth, Stephen Ballaron, Brian Spencer, Lisa McConlogue, Nunilo Cremades, John P. Anderson, Hans-Dieter Junker, Jean-Christophe Rochet, Dale Schenk, Xiao-Hua Chen, John Christodoulou, Renate Sekul, Wenxian Mao, Michael F. Jobling, Carlos W. Bertoncini, Mitali A. Tambe, Inge Ott, Balazs G. Szoke, Shyra J. Gardai, Wherly P. Hoffman, Phuong Nguyen, Michael P. Bova, Jiahui Tao
المساهمون: Cremades, Nunilo [0000-0002-9138-6687], Agard, David A [0000-0003-3512-695X], Apollo - University of Cambridge Repository, Agard, David A. [0000-0003-3512-695X]
المصدر: Scientific reports, vol 9, iss 1
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instnameمصطلحات موضوعية: Amyloid, Protein Folding, 82/47, lcsh:Medicine, Neurodegenerative, Therapeutic targeting, 13, Neuroprotection, Cell Line, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Rare Diseases, Phagocytosis, Fluorescence Resonance Energy Transfer, Humans, Surface plasmon resonance, lcsh:Science, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Parkinson's Disease, Drug discovery, Chemistry, Extramural, lcsh:R, Neurosciences, 631/154, article, Surface Plasmon Resonance, Small molecule, In vitro, 3. Good health, Brain Disorders, High-Throughput Screening Assays, Intrinsically Disordered Proteins, Orphan Drug, 5.1 Pharmaceuticals, Neurological, Synuclein, Biophysics, alpha-Synuclein, lcsh:Q, α synuclein, Development of treatments and therapeutic interventions, 631/378, 030217 neurology & neurosurgery, Neuroscience, Biotechnology
وصف الملف: application/pdf; application/zip; text/xml
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51b2ff3cd4ab186a8300f90d79cdb8d
https://www.repository.cam.ac.uk/handle/1810/300238 -
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المؤلفون: Michael F. Jobling, Donald Rudolph, Karin Regnstrom, Michael P. Bova, Danny Tam, Shendong Yuan, Ying-Zi Xu, David W. G. Wone, Dean R. Artis, Harry Cheung, Hing L. Sham, Zhao Ren, Xiaohua Chen
المصدر: SLAS Discovery. 18:695-704
مصطلحات موضوعية: Streptavidin, High-throughput screening, Hydantoin, Sensitivity and Specificity, Biochemistry, Analytical Chemistry, Small Molecule Libraries, Inhibitory Concentration 50, chemistry.chemical_compound, Biotin, Alzheimer Disease, mental disorders, Amyloid precursor protein, Aspartic Acid Endopeptidases, Humans, Sulfamide, chemistry.chemical_classification, biology, Hydantoins, Ligand binding assay, Combinatorial chemistry, High-Throughput Screening Assays, Enzyme, chemistry, biology.protein, Molecular Medicine, Amyloid Precursor Protein Secretases, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c411e985b4be97bfe6438dd1b4d1b05f
https://doi.org/10.1177/1087057113482138 -
5
المؤلفون: Yunjiang Feng, Thomas Fex, Linda Öster, Anthony R. Carroll, Malcolm Stewart Buchanan, Ronald J. Quinn, Yafeng Xue, Vicky M. Avery, Michael F. Jobling, Johanna Deinum, Rohan A. Davis, Deborah Wessling, John N. A. Hooper
المصدر: Journal of Medicinal Chemistry. 51:3583-3587
مصطلحات موضوعية: Models, Molecular, Magnetic Resonance Spectroscopy, medicine.drug_mechanism_of_action, Stereochemistry, Factor Xa Inhibitor, Chemical Fractionation, Crystallography, X-Ray, Guanidines, chemistry.chemical_compound, Fibrinolytic Agents, Drug Discovery, Antithrombotic, medicine, Animals, IC50, Phenylacetates, chemistry.chemical_classification, Serine protease, Biological Products, Natural product, Molecular Structure, biology, Hydrogen Bonding, Biological activity, Porifera, Enzyme, chemistry, Factor Xa, biology.protein, Molecular Medicine, Fibrinolytic agent, Factor Xa Inhibitors
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المؤلفون: Maria Jose Pajares, Shraddha A. Ravani, Sergei Koslov, Martin J. Lavin, Michael F. Jobling, Julia Kirshner, Mary Helen Barcellos-Hoff, Adam B. Glick, Yosef Shiloh
المصدر: Cancer Research. 66:10861-10869
مصطلحات موضوعية: Keratinocytes, Cancer Research, Infrared Rays, DNA damage, Receptor, Transforming Growth Factor-beta Type I, Cell Cycle Proteins, Ataxia Telangiectasia Mutated Proteins, Protein Serine-Threonine Kinases, Biology, Transforming Growth Factor beta1, Mice, TGF beta signaling pathway, medicine, Animals, Humans, Phosphorylation, Kinase activity, Mice, Inbred BALB C, Tumor Suppressor Proteins, Cell Cycle, Epithelial Cells, Transforming growth factor beta, medicine.disease, Molecular biology, Cell biology, DNA-Binding Proteins, Mice, Inbred C57BL, Oncology, Ataxia-telangiectasia, biology.protein, Signal transduction, Activin Receptors, Type I, Receptors, Transforming Growth Factor beta, DNA Damage, Signal Transduction, Transforming growth factor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80cd6593422cdd7d1ca30b757a6191f5
https://doi.org/10.1158/0008-5472.can-06-2565 -
7
المؤلفون: Roberto Cappai, Andrew J. Thompson, Anthony R. White, Michael F. Jobling, Genevieve Whitty, Colin J. Barrow, Colin L. Masters, Konrad Beyreuther, John A. Hamilton
المصدر: Brain Research. 940:49-54
مصطلحات موضوعية: Male, Macrophage colony-stimulating factor, Time Factors, Amyloid, Cell Survival, Prions, Amyloid beta, medicine.medical_treatment, Biology, Mice, Immune system, medicine, Animals, Macrophage, Molecular Biology, Cells, Cultured, Amyloid beta-Peptides, Dose-Response Relationship, Drug, Microglia, Macrophage Colony-Stimulating Factor, Macrophages, General Neuroscience, Growth factor, DNA, medicine.disease, Peptide Fragments, medicine.anatomical_structure, Immunology, biology.protein, Cancer research, Female, Neurology (clinical), Alzheimer's disease, Cell Division, Developmental Biology
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8
المؤلفون: Catriona McLean, Michael F. Jobling, Fran Maher, Roberto Cappai, Steven J. Collins, Leanne R. Stewart, Anthony R. White, Konrad Beyreuther, Colin L. Masters, Anna M Friedhuber, Colin J. Barrow
المصدر: Journal of Neurochemistry. 73:1557-1565
مصطلحات موضوعية: Circular dichroism, Cell Survival, Prions, Molecular Sequence Data, Neurotoxins, Mutant, Mice, Inbred Strains, Peptide, Biology, Fibril, Biochemistry, Protein Structure, Secondary, Serine, Mice, Structure-Activity Relationship, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Nephelometry and Turbidimetry, Cerebellum, Animals, Humans, Amino Acid Sequence, Protein secondary structure, Cells, Cultured, Sequence Deletion, Mice, Knockout, Neurons, Alanine, chemistry.chemical_classification, Circular Dichroism, Peptide Fragments, Congo red, Mice, Inbred C57BL, Amino Acid Substitution, chemistry, Peptides
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المؤلفون: Shyra J. Gardai, Alexander K. Buell, Nunilo Cremades, Jennifer Johnston, Michael P. Bova, Michael F. Jobling, Gergely Toth, Steven Finkbeiner, Lisa McConlogue, John P. Anderson, Carlos W. Bertoncini, Tuomas P. J. Knowles, Susan L. Roy, John Christodoulou, Karin Regnstrom, Jean-Christophe Rochet, Mitali A. Tambe, Kari Callaway, Ted Yednock, Michele Vendruscolo, Céline Galvagnion, Dale Schenk, San-San Chiou, Gaia Skibinski, Wagner Zago, Christopher M. Dobson
المصدر: PLoS ONE, Vol 9, Iss 2, p e87133 (2014)
PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICETمصطلحات موضوعية: Models, Molecular, Pathology, Parkinson's disease, lcsh:Medicine, Descubrimiento de fármacos, Química Computacional, purl.org/becyt/ford/1 [https], Synapse, Mice, Molecular Cell Biology, Neurobiology of Disease and Regeneration, Molecular Targeted Therapy, lcsh:Science, Phagocytes, Multidisciplinary, Vesicle, Dopaminergic, Parkinson Disease, Molecular Pharmacology, Small molecule, 3. Good health, Neurology, Enfermedad de Parkinson, alpha-Synuclein, Medicine, Biophysic Al Simulations, Membranes and Sorting, CIENCIAS NATURALES Y EXACTAS, Research Article, Biotechnology, medicine.medical_specialty, Drugs and Devices, Drug Research and Development, Neurite, Otras Ciencias Biológicas, Biology, Intrinsically disordered proteins, Models, Biological, Ciencias Biológicas, Small Molecule Libraries, medicine, Animals, Humans, purl.org/becyt/ford/1.6 [https], Binding Sites, Dopaminergic Neurons, lcsh:R, Computational Biology, medicine.disease, nervous system diseases, Intrinsically Disordered Proteins, nervous system, Nerve Degeneration, Synapses, Biología Estructural, lcsh:Q, Pharmacogenomics, Neuroscience
وصف الملف: application/pdf
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المؤلفون: Michael F. Jobling, Colin J. Barrow, Roberto Cappai, Colin L. Masters, Xudong Huang, Konrad Beyreuther, Ashley I. Bush, Anthony R. White
المصدر: Journal of Neurochemistry. 76:1509-1520
مصطلحات موضوعية: Hyperhomocysteinemia, Methionine, biology, Homocysteine, Amyloid beta, Neurotoxicity, Glutathione, Pharmacology, medicine.disease_cause, medicine.disease, Biochemistry, Cellular and Molecular Neuroscience, chemistry.chemical_compound, chemistry, Toxicity, biology.protein, medicine, Oxidative stress