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1دورية أكاديمية
المؤلفون: Lale Ozcan, Canan Kasikara, Arif Yurdagul, George Kuriakose, Brian Hubbard, Michael H Serrano-Wu, Ira Tabas
المصدر: PLoS ONE, Vol 16, Iss 5, p e0246600 (2021)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1932-6203
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2دورية أكاديمية
المؤلفون: Matthew C Clifton, David M Dranow, Alison Leed, Ben Fulroth, James W Fairman, Jan Abendroth, Kateri A Atkins, Ellen Wallace, Dazhong Fan, Guoping Xu, Z J Ni, Doug Daniels, John Van Drie, Guo Wei, Alex B Burgin, Todd R Golub, Brian K Hubbard, Michael H Serrano-Wu
المصدر: PLoS ONE, Vol 10, Iss 4, p e0125010 (2015)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1932-6203
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المؤلفون: Louis Borrillo, Brian K. Hubbard, Deborah T. Hung, Jean-Philippe Côté, Kristina Klobucar, Jakob Magolan, Jeffrey L Gaulin, Eric D. Brown, Shawn French, Jarrod W. Johnson, Amelia Bing Ya Guo, Michael H Serrano-Wu, Katie K Lee
المصدر: ACS chemical biology. 16(5)
مصطلحات موضوعية: 0301 basic medicine, Acinetobacter baumannii, Lipopolysaccharides, Cell Membrane Permeability, Lipopolysaccharide, medicine.drug_class, Polymyxin, 01 natural sciences, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Cell Wall, Vancomycin, Quinoxalines, Amphiphile, medicine, Escherichia coli, Inner membrane, Spiro Compounds, Polymyxins, Enzyme Inhibitors, biology, 010405 organic chemistry, Chemistry, Drug Synergism, General Medicine, biology.organism_classification, 0104 chemical sciences, Anti-Bacterial Agents, High-Throughput Screening Assays, Klebsiella pneumoniae, 030104 developmental biology, Mechanism of action, Pseudomonas aeruginosa, Biophysics, Molecular Medicine, medicine.symptom, Bacterial outer membrane, Bacteria, Intracellular, Bacterial Outer Membrane Proteins
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المؤلفون: Dirk Schnappinger, Rebecca E Audette, Kristine M. Guinn, Michael Fitzgerald, Michelle Gardner, Carolina Trujillo, Joshua Davis, Joshua B. Wallach, Jessica T. Pinkham, Deborah T. Hung, Nirmalya Bandyopadhyay, Mary Stanley, Natalia Betancourt, Christina Gallo, Megan K. Proulx, Jennifer A McConnell, Christopher M. Sassetti, Sofia Kennedy, Elisabeth Meyer, James Gomez, Kayla Delano, Paula A Pino, Emily LaVerriere, K. G. Papavinasasundaram, Eric S. Lander, Eric J. Rubin, Michael H Serrano-Wu, Emma Office, Caitlin E Moss, Naomi Song, Nadine Ruecker, Thomas R. Ioerger, Israel Da Silva, Matthew Thompson, Christopher Watson, Sabine Ehrt, Shoko Wakabayashi, Brian K. Hubbard, Tomohiko Kawate, Kenan C. Murphy, Rebecca Korn, Raymond M. Nietupski, Eachan O. D. Johnson, Aaron Golas
المصدر: Nature. 571:72-78
مصطلحات موضوعية: medicine.drug_class, Antibiotics, Antitubercular Agents, Microbial Sensitivity Tests, Drug resistance, Computational biology, DNA gyrase, Substrate Specificity, Small Molecule Libraries, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, Folic Acid, RNA polymerase, Drug Discovery, medicine, Topoisomerase II Inhibitors, Tuberculosis, Molecular Targeted Therapy, Gene, 030304 developmental biology, 0303 health sciences, Multidisciplinary, biology, 030306 microbiology, Drug discovery, Tryptophan, Reproducibility of Results, Drug Resistance, Microbial, biology.organism_classification, Mycolic Acids, chemistry, DNA Gyrase, Chemical genetics, Gene Deletion
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5
المؤلفون: George Kuriakose, Arif Yurdagul, Brian K. Hubbard, Ira Tabas, Lale Ozcan, Canan Kasikara, Michael H. Serrano-Wu
مصطلحات موضوعية: Necrosis, Triglyceride, business.industry, Fibrous cap, Type 2 diabetes, Metabolism, Pharmacology, Carbohydrate metabolism, medicine.disease, Lesion, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Medicine, Glucose homeostasis, medicine.symptom, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::07f52ddd0248eb7bb92e004f83085af3
https://doi.org/10.1101/2021.01.12.426264 -
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المؤلفون: Mary Stanley, Joshua B. Wallach, Michael H Serrano-Wu, Eachan O. D. Johnson, Paula A Pino, Aaron Golas, Rebecca Korn, Naomi Song, Caitlin E Moss, Eric S. Lander, Jessica T. Pinkham, Joshua Davis, Nadine Ruecker, Dirk Schnappinger, Christina Gallo, Tomohiko Kawate, Nirmalya Bandyopadhyay, Deborah T. Hung, Elisabeth Meyer, Michelle Gardner, Jennifer A McConnell, Thomas R. Ioerger, Carolina Trujillo, Megan K. Proulx, Israel Da Silva, Michael Fitzgerald, Kayla Delano, Emma Office, Kristine M. Guinn, Rebecca E Audette, Christopher Watson, K. G. Papavinasasundaram, Eric J. Rubin, Christopher M. Sassetti, Emily LaVerriere, Brian K. Hubbard, Ray Nietupski, Kenan C. Murphy, James Gomez, Matthew Thompson, Sabine Ehrt, Shoko Wakabayashi, Natalia Betancourt
مصطلحات موضوعية: medicine.drug_class, Drug discovery, Antibiotics, Computational biology, Folate biosynthesis, Biology, biology.organism_classification, DNA gyrase, Mycobacterium tuberculosis, chemistry.chemical_compound, chemistry, RNA polymerase, medicine, Gene, Chemical genetics
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1a1b6871077bae65e4d61671b2b402
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المؤلفون: Robert H. Bates, Deborah T. Hung, Eva Maria Lopez-Roman, Brian K. Hubbard, Katie K. Lee, David Barros-Aguirre, Laura Guijarro-López, Stewart L. Fisher, Zuozhong Peng, James Gomez, Michael H Serrano-Wu, Yunxing Yin, Raquel Fernandez-Menendez, Chao Fang, Raymond M. Nietupski
المصدر: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madridمصطلحات موضوعية: 0301 basic medicine, In vivo efficacy, Quinoline-2-carboxamide, Clinical Biochemistry, Antitubercular Agents, Drug Evaluation, Preclinical, Pharmaceutical Science, Microbial Sensitivity Tests, 010402 general chemistry, 01 natural sciences, Biochemistry, Article, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Bacterial Proteins, In vivo, Coumarins, Drug Discovery, Structure–activity relationship, Animals, Tuberculosis, Anti tubercular, Molecular Biology, ADME, chemistry.chemical_classification, biology, Chemistry, Organic Chemistry, Quinoline, FadD32 inhibitor, Structure-activity relationship, biology.organism_classification, Coumarin, Combinatorial chemistry, 0104 chemical sciences, Disease Models, Animal, 030104 developmental biology, Enzyme, Quinolines, Molecular Medicine
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المؤلفون: Serge Cremers, Devram Sampat Ghorpade, Shi-Xian Deng, Brian K. Hubbard, Michael H. Serrano-Wu, Donald W. Landry, Xiaoming Xu, Matthias Gaestel, Lale Ozcan, Ira Tabas, Tiffany Thomas
المصدر: Diabetes
مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Mice, Obese, Type 2 diabetes, Protein Serine-Threonine Kinases, Biology, Mice, Insulin resistance, Ca2+/calmodulin-dependent protein kinase, Internal medicine, Internal Medicine, medicine, Animals, Glucose homeostasis, Enzyme Inhibitors, Protein kinase A, Mice, Knockout, MAPKAPK2, Intracellular Signaling Peptides and Proteins, medicine.disease, Metformin, Insulin receptor, Metabolism, Endocrinology, biology.protein, Insulin Resistance, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90d1762ed9a3c4a096aed1725c3453b
https://doi.org/10.2337/db14-1945 -
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المؤلفون: Brendan R. D'Souza, James W. Fairman, Ben Fulroth, Michael H Serrano-Wu, Virendar K. Kaushik, Todd R. Golub, Brian K. Hubbard, Guo Wei, Chao Fang, Patrick McCarren, Clementine Feau, Christopher F. Thompson, Yikai Wang, Alison Leed, Matthew C. Clifton, Lili Wang, Michelle Palmer
المصدر: ACS Medicinal Chemistry Letters. 5:1308-1312
مصطلحات موضوعية: Myeloid, Stereochemistry, Organic Chemistry, Cell, Diastereomer, Biology, medicine.disease, Biochemistry, Leukemia, medicine.anatomical_structure, BH3 peptide, Direct binding, Drug Discovery, medicine, Molecule, MCL1
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المؤلفون: Michael H. Serrano-Wu, Alan D. Neubert, Katsumasa Nakajima, Jingzhou Li, Qing Yang, David Truong, Kevin B. Clairmont, Renee Commerford, Aaron Kanter, Thomas Daniels, Young-Shin Kwak, Paul V. Szklennik, Yongjin Gong, Vivienne Tedesco, Gary M. Coppola, Brian K. Hubbard, Ricardo E. Chatelain, Thomas A. Gilmore, Charles D. Meyers, Forster Cornelia J, Monish Jain, James Thompson
المصدر: Journal of medicinal chemistry. 60(11)
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Benzimidazole, medicine.medical_specialty, Adolescent, Administration, Oral, Body weight, Diet, High-Fat, Weight Gain, Placebos, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Dogs, Double-Blind Method, Internal medicine, Drug Discovery, medicine, Potency, Animals, Humans, Diacylglycerol O-Acyltransferase, Obesity, Enzyme Inhibitors, Triglycerides, Meal, Middle Aged, Postprandial Period, Small intestine, Bioavailability, Rats, 030104 developmental biology, Postprandial, medicine.anatomical_structure, Endocrinology, chemistry, 030220 oncology & carcinogenesis, Molecular Medicine, Female, Diet-induced obese
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