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1
المؤلفون: Elizabeth Ann Gleason, L. Nathan Tumey, Steven M. Murphy, George Mbella Ekema, Bruce Sherf, Robert W. Mays, Joel Danzig, Jianping Song, John J. Harrington, Marc Palmer, Doug Hanniford, Gary Pawlowski, Michael J. Robarge, Chris Doucette, Margaret Loftus, Karen Hunady, Youssef L. Bennani, Alain Stricker-Krongrad, Kurt R. Brunden
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:3287-3290
مصطلحات موضوعية: Indoles, Receptors, Prostaglandin, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Chemical synthesis, Thromboxane A2, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Receptors, Immunologic, Molecular Biology, Prostaglandin D2 receptor, Indole test, Sulfonamides, Esterification, Chemistry, Organic Chemistry, Antagonist, In vitro, Molecular Medicine, Prostaglandin D2, Ramatroban, medicine.drug
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2
المؤلفون: William F. Hodnick, Luis Llamas, Thomas C. Dent, Jianping Song, Youssef L. Bennani, Michael J. Robarge, John J. Harrington, Alain Stricker-Krongrad, Kurt R. Brunden, Bayard Huck, Chris Crumrine
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:4130-4134
مصطلحات موضوعية: Agonist, Nitrogen, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Structure-Activity Relationship, Dogs, Drug Discovery, medicine, Animals, Structure–activity relationship, Receptor, Molecular Biology, G protein-coupled receptor, chemistry.chemical_classification, Organic Chemistry, Biological activity, Feeding Behavior, Rats, Serotonin Receptor Agonists, chemistry, Drug Design, Molecular Medicine, 5-HT2C receptor agonist, Serotonin 5-HT2 Receptor Agonists, Half-Life, Tricyclic
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3
المؤلفون: Luis Llamas, William F. Hodnick, Michael J. Robarge, Bayard Huck, Chris Crumrine, Youssef L. Bennani, John J. Harrington, Thomas C. Dent, Alain Stricker-Krongrad, Kurt R. Brunden, Jianping Song
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:2891-2894
مصطلحات موضوعية: Agonist, Pyrimidine, medicine.drug_class, media_common.quotation_subject, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Bridged Bicyclo Compounds, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Receptor, Serotonin, 5-HT2C, medicine, Animals, Amines, Receptor, Molecular Biology, media_common, Octane, Aza Compounds, Molecular Structure, Organic Chemistry, Stereoisomerism, Appetite, Small molecule, Rats, 5-HT2C receptor, Pyrimidines, chemistry, Molecular Medicine, Serotonin 5-HT2 Receptor Agonists
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4
المؤلفون: John J. Harrington, Chris Doucette, Karen Hunady, Doug Hanniford, Margaret Loftus, Varga Norbert, L. Nathan Tumey, Daniel P. Silver, Elizabeth Ann Gleason, David C. Bom, Jianping Song, Joel Danzig, Marc Palmer, Steven M. Murphy, Michael J. Robarge, Gary Pawlowski, Youssef L. Bennani, George Mbella Ekema, Bruce Sherf, Robert W. Mays, Alain Stricker-Krongrad, Kurt R. Brunden
المصدر: Bioorganic & Medicinal Chemistry Letters. 15:1749-1753
مصطلحات موضوعية: Isostere, Receptors, Prostaglandin, Clinical Biochemistry, Carbazoles, Molecular Conformation, Pharmaceutical Science, Prostaglandin, Pharmacology, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Isomerism, Drug Discovery, medicine, Anti-Asthmatic Agents, Receptors, Immunologic, Receptor, Molecular Biology, Sulfonamides, Molecular Structure, Organic Chemistry, Antagonist, Chemotaxis, Eosinophil, medicine.anatomical_structure, Models, Chemical, chemistry, Molecular Medicine, Ramatroban, Prostaglandin D2, medicine.drug
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5
المؤلفون: Robert R. Luedtke, Michael J. Robarge, Amy Hauck Newman, Christina J Bennett, Jianjing Cao, Rebekah A Freeman
المصدر: Bioorganic & Medicinal Chemistry Letters. 13:2179-2183
مصطلحات موضوعية: Chemical Phenomena, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Carboxamide, CHO Cells, Transfection, Biochemistry, Chemical synthesis, Piperazines, Structure-Activity Relationship, Neurochemical, Dopamine receptor D3, Dopamine, Cricetinae, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, Bicyclic molecule, Chemistry, Physical, Receptors, Dopamine D2, Chemistry, Organic Chemistry, Receptors, Dopamine D3, Stereoisomerism, Dopamine D2 Receptor Antagonists, Lipophilicity, Butanes, Dopamine Antagonists, Molecular Medicine, Indicators and Reagents, medicine.drug
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6
المؤلفون: and Andrew Thurkauf, Andrzej Kieltyka, Amy Hauck Newman, Michael J. Robarge, Robbin Brodbeck, Stephen M. Husbands
المصدر: Journal of Medicinal Chemistry. 44:3175-3186
مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Carboxamide, CHO Cells, Ligands, Binding, Competitive, Chemical synthesis, Piperazines, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Neurochemical, Dopamine receptor D3, Cricetinae, Drug Discovery, medicine, Animals, Combinatorial Chemistry Techniques, Humans, Receptor, Fluorenes, Receptors, Dopamine D2, Chinese hamster ovary cell, Receptors, Dopamine D4, Receptors, Dopamine D3, Amides, Piperazine, Biochemistry, chemistry, Drug Design, Molecular Medicine, Linker
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7
المصدر: Journal of Medicinal Chemistry. 42:3502-3509
مصطلحات موضوعية: Male, Models, Molecular, Molecular model, Stereochemistry, Dopamine, Nerve Tissue Proteins, Rats, Sprague-Dawley, chemistry.chemical_compound, Cocaine, Dopamine Uptake Inhibitors, Drug Discovery, medicine, Animals, Dopamine transporter, Dopamine Plasma Membrane Transport Proteins, Binding Sites, Membrane Glycoproteins, biology, Bicyclic molecule, Brain, Membrane Transport Proteins, Tropane, Benztropine, Rats, chemistry, biology.protein, Molecular Medicine, Carrier Proteins, Protein Binding, Tropanes, Binding domain, medicine.drug
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8
المؤلفون: Sari Izenwasser, Jonathan L. Katz, Clifford George, Michael J. Robarge, Ileana M. Howard, Theresa A. Kopajtic, Sharine L. Wittkopp, Amy Hauck Newman
المصدر: Journal of medicinal chemistry. 44(4)
مصطلحات موضوعية: Male, Serotonin, Stereochemistry, Dopamine, Nerve Tissue Proteins, In Vitro Techniques, Binding, Competitive, Rats, Sprague-Dawley, chemistry.chemical_compound, Norepinephrine, Structure-Activity Relationship, Drug Discovery, Dopamine Uptake Inhibitors, medicine, Animals, Biogenic Monoamines, Serotonin transporter, Dopamine transporter, Serotonin Plasma Membrane Transport Proteins, Dopamine Plasma Membrane Transport Proteins, Membrane Glycoproteins, Norepinephrine Plasma Membrane Transport Proteins, biology, Symporters, Receptor, Muscarinic M1, Brain, Membrane Transport Proteins, Tropane, Nisoxetine, Receptors, Muscarinic, Benztropine, Rats, Monoamine neurotransmitter, chemistry, Norepinephrine transporter, biology.protein, Molecular Medicine, Carrier Proteins, medicine.drug, Tropanes
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9
المؤلفون: Gregory E. Agoston, Jonathan L. Katz, Clifford George, Michael J. Robarge, Sari Izenwasser, Theresa A. Kopajtic, Amy Hauck Newman
المصدر: Journal of medicinal chemistry. 43(6)
مصطلحات موضوعية: Male, Models, Molecular, Stereochemistry, Dopamine Plasma Membrane Transport Proteins, Dopamine, Dopamine Agents, Stereoisomerism, Nerve Tissue Proteins, Ligands, Binding, Competitive, Rats, Sprague-Dawley, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Dopamine Uptake Inhibitors, medicine, Animals, Dopamine transporter, Membrane Glycoproteins, biology, Receptor, Muscarinic M1, Putamen, Membrane Transport Proteins, Tropane, Receptors, Muscarinic, Benztropine, Rats, chemistry, biology.protein, Molecular Medicine, Carrier Proteins, Binding domain, medicine.drug, Tropanes