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1دورية أكاديمية
المؤلفون: Mohammad Arastoo, Michael P. Mazanetz, Sonya Miller, Helen Shiells, Claire Hull, Keith Robinson, John M. D. Storey, Charles R. Harrington, Claude M. Wischik
المصدر: International Journal of Molecular Sciences, Vol 24, Iss 18, p 13747 (2023)
مصطلحات موضوعية: hydromethylthionine, hypoxaemia, anti-hypoxaemia, COVID-19, SARS-CoV-2, Biology (General), QH301-705.5, Chemistry, QD1-999
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Michael P. Mazanetz, Charles A. Laughton, Peter M. Fischer
المصدر: Molecules, Vol 19, Iss 7, Pp 9134-9159 (2014)
مصطلحات موضوعية: active site pressurisation, kinase, structure-based drug design, protein flexibility, molecular dynamics, Organic chemistry, QD241-441
وصف الملف: electronic resource
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المؤلفون: Ewa I. Chudyk, Michael P. Mazanetz, Charlotte H F Goode
المصدر: Current Medicinal Chemistry. 27:6458-6479
مصطلحات موضوعية: 0301 basic medicine, Computer science, Big data, Ligands, 01 natural sciences, Biochemistry, 03 medical and health sciences, Drug Discovery, Pharmacology, Virtual screening, business.industry, Drug discovery, Organic Chemistry, Timeline, Data science, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Workflow, Drug development, Analytics, Drug Design, Paradigm shift, Molecular Medicine, business, Software
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c078a79f2dd982bf7b214e47ddcb2f
https://doi.org/10.2174/0929867326666190409141016 -
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المؤلفون: Tom Coulter, Michael P. Mazanetz, Richard D. Perrins, Yinping Ma, Yubo Wu, Angela Robinson, John Porter, Kelly Conlon, Yao Ding, Sarah J.M. Hale
المصدر: Bioorganic & Medicinal Chemistry Letters. 30:127634
مصطلحات موضوعية: Models, Molecular, Drug, Carcinoma, Hepatocellular, media_common.quotation_subject, Clinical Biochemistry, Pharmaceutical Science, Nanoconjugates, Maytansinoid, 01 natural sciences, Biochemistry, Mice, chemistry.chemical_compound, In vivo, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Maytansine, Molecular Biology, media_common, 010405 organic chemistry, Liver Neoplasms, Organic Chemistry, medicine.disease, Antineoplastic Agents, Phytogenic, Tubulin Modulators, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Colloidal gold, Hepatocellular carcinoma, Drug delivery, Cancer research, Molecular Medicine, Nanomedicine, Gold, Growth inhibition
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5
المؤلفون: Charles A. Laughton, Michael P. Mazanetz, Peter Fischer
المصدر: Molecules, Vol 19, Iss 7, Pp 9134-9159 (2014)
Molecules
Molecules; Volume 19; Issue 7; Pages: 9134-9159مصطلحات موضوعية: kinase, active site pressurisation, Pharmaceutical Science, Computational biology, Disease, Molecular Dynamics Simulation, Protein Structure, Secondary, Article, Analytical Chemistry, lcsh:QD241-441, Adenosine Triphosphate, lcsh:Organic chemistry, Alzheimer Disease, Catalytic Domain, Drug Discovery, Enzyme Stability, Humans, Physical and Theoretical Chemistry, Protein Kinase Inhibitors, Flexibility (engineering), Principal Component Analysis, biology, ATP synthase, Kinase, Cyclin-dependent kinase 5, protein flexibility, Organic Chemistry, Active site, structure-based drug design, molecular dynamics, Biochemistry, Chemistry (miscellaneous), Drug Design, biology.protein, Molecular Medicine, Protein Kinases, Protein Binding
وصف الملف: application/pdf
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6
المؤلفون: Julien Michel, Michael P. Mazanetz, Michelle Southey, Georgios Gerogiokas, Richard H. Henchman, Alexander Heifetz, Michael J. Bodkin, Richard J. Law
المصدر: Gerogiokas, G, Southey, M W Y, Mazanetz, M P, Heifetz, A, Bodkin, M, Law, R J, Henchman, R H & Michel, J 2016, ' Assessment of Hydration Thermodynamics at Protein Interfaces with Grid Cell Theory ', Journal of Physical Chemistry B (Soft Condensed Matter and Biophysical Chemistry) . https://doi.org/10.1021/acs.jpcb.6b07993
Gerogiokas, G, Southey, M W Y, Mazanetz, M P, Heifetz, A, Bodkin, M, Law, R J, Henchman, R H & Michel, J 2016, ' Assessment of Hydration Thermodynamics at Protein Interfaces with Grid Cell Theory ', Journal of Physical Chemistry B, vol. 120, no. 40, pp. 10442-10452 . https://doi.org/10.1021/acs.jpcb.6b07993مصطلحات موضوعية: 0301 basic medicine, Static Electricity, Thermodynamics, Molecular Dynamics Simulation, 010402 general chemistry, Ligands, 01 natural sciences, 03 medical and health sciences, Molecular dynamics, Manchester Institute of Biotechnology, Materials Chemistry, Molecule, Physical and Theoretical Chemistry, Amino Acids, chemistry.chemical_classification, Binding Sites, Continuum electrostatics, Proteins, Water, Grid cell, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, 0104 chemical sciences, Surfaces, Coatings and Films, Amino acid, Protein Structure, Tertiary, 030104 developmental biology, chemistry, Polar
وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6779a77fb243fde9b24657f322433a52
https://www.pure.ed.ac.uk/ws/files/28060020/Gerogiokas_GCTproteins_JPCB_2016_OA.pdf -
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المؤلفون: Michael P. Mazanetz
المصدر: In Silico Drug Discovery and Design. :64-79
مصطلحات موضوعية: Physics, Drug discovery, Nanotechnology, Quantum
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f9c2adffa016f0a9b50518e4708d420e
https://doi.org/10.4155/ebo.13.291 -
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المؤلفون: Michael P. Mazanetz, Osamu Ichihara, Yuri Alexeev, Dmitri G. Fedorov
المصدر: Current Topics in Medicinal Chemistry. 12:2013-2033
مصطلحات موضوعية: Models, Molecular, Chemistry, Ab initio, Computational Biology, Nanotechnology, General Medicine, Ligands, Method development, Computational science, Fragment (logic), Drug Design, Drug Discovery, Quantum Theory, GAMESS, Quantum, Software, Fragment molecular orbital, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06dab74837eccab76104555d6fa87ef2
https://doi.org/10.2174/156802612804910269 -
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المؤلفون: Alexander Heifetz, Mark J. Gemkow, Michael P. Mazanetz, Richard J. Law, Clemens Möller, Andreas Ebneth, Adam James Davenport
المصدر: ASSAY and Drug Development Technologies. 8:781-789
مصطلحات موضوعية: Models, Molecular, Patch-Clamp Techniques, In silico, hERG, Biology, Pharmacology, Structure-Activity Relationship, chemistry.chemical_compound, Cricetulus, Cricetinae, Drug Discovery, medicine, Animals, Humans, Receptors, Histamine H3, Computer Simulation, Channel blocker, Antagonist, medicine.disease, Ether-A-Go-Go Potassium Channels, High-Throughput Screening Assays, chemistry, Drug Design, biology.protein, Molecular Medicine, Histamine H3 receptor, Pharmacophore, Histamine, Histamine H3 Antagonists, Narcolepsy
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6909e1bceaad34b6d9bf166428dcdd8
https://doi.org/10.1089/adt.2010.0322 -
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المصدر: QSAR & Combinatorial Science. 28:878-884
مصطلحات موضوعية: Flexibility (engineering), Quantitative structure–activity relationship, biology, Chemistry, Organic Chemistry, Active site, Variance (accounting), Computer Science Applications, Molecular dynamics, Computational chemistry, Distortion, Drug Discovery, biology.protein, Target protein, Binding site, Biological system
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