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1دورية أكاديمية
المؤلفون: Maria I. Edilova, Jaclyn C. Law, Safoura Zangiabadi, Kenneth Ting, Achire N. Mbanwi, Andrea Arruda, David Uehling, Methvin Isaac, Michael Prakesch, Rima Al-awar, Mark D. Minden, Ali A. Abdul-Sater, Tania H. Watts
المصدر: OncoImmunology, Vol 10, Iss 1 (2021)
مصطلحات موضوعية: chronic lymphocytic leukemia, tnfr-associated factors (trafs), protein kinase n1, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2162-402X
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2دورية أكاديمية
المؤلفون: Nardin Nano, Francisca Ugwu, Thiago V. Seraphim, Tangzhi Li, Gina Azer, Methvin Isaac, Michael Prakesch, Leandro R. S. Barbosa, Carlos H. I. Ramos, Alessandro Datti, Walid A. Houry
المصدر: Biomolecules, Vol 10, Iss 4, p 605 (2020)
مصطلحات موضوعية: RUVBL2, RUVBL1, Sorafenib, AAA+ proteins, Inhibition, Microbiology, QR1-502
وصف الملف: electronic resource
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المؤلفون: David R. Kaplan, Rima Al-awar, Jeffrey L. Wrana, Meredith S. Irwin, Methvin Isaac, Michael Prakesch, David Uehling, Mayumi Fujitani, Alessandro Datti, Natalie Grinshtein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2375d4cb47fae034b866f25bfa60c921
https://doi.org/10.1158/0008-5472.22391145 -
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المؤلفون: David R. Kaplan, Rima Al-awar, Jeffrey L. Wrana, Meredith S. Irwin, Methvin Isaac, Michael Prakesch, David Uehling, Mayumi Fujitani, Alessandro Datti, Natalie Grinshtein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::816c2e31dec70e8865a37b7f78ef49d4
https://doi.org/10.1158/0008-5472.c.6503166.v1 -
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المؤلفون: John David Konda, Craig Strathdee, Taira Kiyota, David Uehling, Kim Chan Chung, Richard Marcellus, Rima Al-awar, Methvin Isaac, Rodger E. Tiedemann, Chungyee Leung-Hagesteijn, Spencer Ler, Ahmed Aman, Michael Prakesch, Carly Griffin, Andrew X Zhang, Ayome Abibi, Gennady Poda, Babu Joseph, Julie Grouleff, Ratheesh Subramaniam
المصدر: Journal of medicinal chemistry. 64(15)
مصطلحات موضوعية: Models, Molecular, Cell Survival, Antineoplastic Agents, 03 medical and health sciences, Mice, Structure-Activity Relationship, 0302 clinical medicine, Drug Discovery, medicine, Animals, Humans, Receptor, IC50, Protein Kinase Inhibitors, Multiple myeloma, 030304 developmental biology, Cell Proliferation, 0303 health sciences, Gene knockdown, G protein-coupled receptor kinase, Dose-Response Relationship, Drug, Molecular Structure, Bortezomib, Kinase, Chemistry, medicine.disease, G-Protein-Coupled Receptor Kinases, Small molecule, 3. Good health, 030220 oncology & carcinogenesis, Drug Design, Cancer research, Quinazolines, Molecular Medicine, Drug Screening Assays, Antitumor, Multiple Myeloma, medicine.drug
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المؤلفون: Safoura Zangiabadi, Tania H. Watts, Methvin Isaac, Achire N. Mbanwi, Jaclyn C. Law, Michael Prakesch, Maria I. Edilova, Rima Al-awar, Kenneth Ting, Ali A. Abdul-Sater, Mark D. Minden, Andrea Arruda, David Uehling
المصدر: OncoImmunology, Vol 10, Iss 1 (2021)
Oncoimmunology
article-version (VoR) Version of Recordمصطلحات موضوعية: Chronic lymphocytic leukemia, Immunology, TRAF1, tnfr-associated factors (trafs), chemistry.chemical_compound, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, medicine, Humans, Immunology and Allergy, Naphthyridines, education, Protein Kinase Inhibitors, Protein Kinase C, Protein kinase C, RC254-282, B cell, Original Research, protein kinase n1, 030304 developmental biology, 0303 health sciences, education.field_of_study, Kinase, Chemistry, Venetoclax, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC581-607, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, TNF Receptor-Associated Factor 1, Raji cell, 3. Good health, Protein kinase N1, Tnfr superfamily, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Cancer research, chronic lymphocytic leukemia, Immunologic diseases. Allergy, Refractory Chronic Lymphocytic Leukemia, business, Adaptor molecule, Research Article, Signal Transduction, 030215 immunology
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المؤلفون: Michael Prakesch, Rima Al-awar, Ahmed Aman, Pierre Maisonneuve, Lauren Caldwell, Derek F. Ceccarelli, Ganna Posternak, Theo Goullet de Rugy, Mikko Taipale, Igor Kurinov, Julia Kitaygorodsky, Pavel Mader, Karen Colwill, Gennady Poda, Brett Larsen, Anne-Claude Gingras, Kin Chan, Jeff Wrana, Ting Jin, Salima Daou, Marc Therrien, Stephen Orlicky, Hugo Lavoie, Daniel Durocher, Xiaojing Tang, Cassandra J. Wong, Frank Sicheri, David Uehling, Robert A. Batey, Zhe Yin, Stefan Maier
المصدر: Nat Chem Biol
مصطلحات موضوعية: MAPK/ERK pathway, Models, Molecular, Proto-Oncogene Proteins B-raf, MAP Kinase Signaling System, Mutant, Antineoplastic Agents, Apoptosis, Plasma protein binding, Biology, Article, 03 medical and health sciences, Mice, Structure-Activity Relationship, Cell Line, Tumor, Animals, Humans, Molecular Targeted Therapy, Phosphorylation, Extracellular Signal-Regulated MAP Kinases, Molecular Biology, Protein Kinase Inhibitors, neoplasms, 030304 developmental biology, Cell Proliferation, Regulation of gene expression, Mitogen-Activated Protein Kinase Kinases, 0303 health sciences, Molecular Structure, Cell growth, Kinase, Ubiquitin, 030302 biochemistry & molecular biology, Cell Biology, digestive system diseases, Thalidomide, Gene Expression Regulation, Drug Resistance, Neoplasm, Drug Design, Mutation, Proteolysis, Cancer research, Intercellular Signaling Peptides and Proteins, Female, Signal transduction, Peptides, V600E, Protein Binding, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d3e2daaba5123ff078df9ce3f29cce
https://europepmc.org/articles/PMC7862923/ -
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المؤلفون: Gennady Poda, Marko Jakopović, Levon Halabelian, Methvin Isaac, Nikolina Radulovich, Michael Prakesch, Caroline Huard, Ahmed Aman, Dhananjay Joshi, Zhong Yao, Manuel Chan, Wiebke Schormann, Richard Marcellus, Babu Joseph, Rima Al-awar, Luka Drecun, Mohammed Mohammed, Li Niu, Brigitte L. Thériault, María Sánchez-Osuna, David Uehling, Ahmed Mamai, Ming-Sound Tsao, Jasmin Coulombe-Huntington, Taira Kiyota, Evelyne Lima-Fernandes, Punit Saraon, Ankit Rai, Jamie Snider, David W. Andrews, Cheryl H. Arrowsmith, Farzaneh Aboualizadeh, Natasha B. Leighl, Miroslav Samaržija, Victoria Wong, Anna Lyakisheva, Mike Tyers, Ratheesh Subramanian, Adrian G. Sacher, Fengling Li, Masoud Vedadi, Igor Stagljar, Shivanthy Pathmanathan
المصدر: Journal of Molecular Biology. 433:167294
مصطلحات موضوعية: Mutant, Coatomer Protein, Receptor tyrosine kinase, Structural Biology, Drug Discovery, medicine, Humans, Epidermal growth factor receptor, Lung cancer, Protein Kinase Inhibitors, Molecular Biology, Secretory pathway, coatomer protein complex beta 2 (COPB2), epidermal growth factor receptor (EGFR), lung cancer, endoplasmic reticulum stress, receptor tyrosine kinase, Gene knockdown, biology, Chemistry, Endoplasmic reticulum, Receptor Protein-Tyrosine Kinases, Endoplasmic Reticulum Stress, medicine.disease, COPB2, ErbB Receptors, Gene Expression Regulation, Neoplastic, Mutation, Cancer research, biology.protein, Drug Screening Assays, Antitumor, Protein Processing, Post-Translational, Signal Transduction
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المؤلفون: Methvin Isaac, Walid A. Houry, Thiago V. Seraphim, Alessandro Datti, Carlos H.I. Ramos, Francisca Ugwu, Leandro R.S. Barbosa, Tangzhi Li, Michael Prakesch, Gina Azer, Nardin Nano
المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Biomolecules
Volume 10
Issue 4
Biomolecules, Vol 10, Iss 605, p 605 (2020)مصطلحات موضوعية: 0301 basic medicine, Sorafenib, Telomerase, DNA damage, RUVBL2, AAA+ proteins, ATPase, lcsh:QR1-502, RUVBL1, medicine.disease_cause, Biochemistry, Article, lcsh:Microbiology, Chromatin remodeling, Inhibitory Concentration 50, Protein Aggregates, 03 medical and health sciences, 0302 clinical medicine, Inhibition, medicine, Humans, Enzyme Inhibitors, Molecular Biology, biology, Chemistry, DNA Helicases, ESPALHAMENTO DE RAIOS X A BAIXOS ÂNGULOS, AAA proteins, 3. Good health, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Cancer research, ATPases Associated with Diverse Cellular Activities, Mutant Proteins, Protein Multimerization, Carrier Proteins, Carcinogenesis, medicine.drug
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c49761871886eb79d88df2af7f9142d
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10
المؤلفون: Michael Prakesch, Ahmed Aman, Victoria Wong, Leanne E Wybenga-Groot, Michael F. Moran, Nika Vučković, Adrian G. Sacher, Luka Drecun, Miroslav Samaržija, Alessandro Datti, Nhu-An Pham, Zhong Yao, Gennady Poda, Punit Saraon, Marko Jakopović, Babu Joseph, Jenny Wang, Konstantin Weiss, Nikolina Radulovich, Anna Akhmanova, Jin H Park, Adriana Vučetić, Anna Lyakisheva, Ming-Sound Tsao, Ankit Rai, David Uehling, Farzaneh Aboualizadeh, Jamie Snider, Natasha B. Leighl, Frances A. Shepherd, Richard Marcellus, Rima Al-awar, Igor Stagljar, Yannis Kalaidzidis, Brigitte L. Thériault, Marino Zerial, Shivanthy Pathmanathan, Yuhui Wang
المساهمون: Sub Cell Biology, Celbiologie
المصدر: Nature Chemical Biology, 16(5), 577. Nature Publishing Group
مصطلحات موضوعية: Lung Neoplasms, Carcinoma, Non-Small-Cell Lung/drug therapy, CHECKPOINT KINASE INHIBITOR, Drug Resistance, PROTEIN, Non-Small-Cell Lung/drug therapy, Drug resistance, Receptor tyrosine kinase, Genes, Reporter, Carcinoma, Non-Small-Cell Lung, ErbB Receptors/antagonists & inhibitors, Small Molecule Libraries/pharmacology, Drug Discovery, High-Throughput Screening Assays/methods, Epidermal growth factor receptor, Luciferases/genetics, Phosphorylation, FLT3, Luciferases, 0303 health sciences, Tumor, biology, Kinase, Drug discovery, 030302 biochemistry & molecular biology, PHASE-I, RESISTANCE, AZD7762, AZD9291, Phosphorylation/drug effects, ErbB Receptors, DNA Nucleotidyltransferases, medicine.symptom, Tyrosine kinase, Staurosporine/analogs & derivatives, Drug Resistance, Neoplasm/genetics, Cell Line, Small Molecule Libraries, 03 medical and health sciences, Cell surface receptor, Cell Line, Tumor, medicine, Humans, Lung Neoplasms/drug therapy, Molecular Biology, Reporter, Protein Kinase Inhibitors, 030304 developmental biology, Neoplasm/genetics, Carcinoma, Reproducibility of Results, Cell Biology, Staurosporine, High-Throughput Screening Assays, Mechanism of action, Genes, Drug Resistance, Neoplasm, Protein Kinase Inhibitors/pharmacology, DNA Nucleotidyltransferases/genetics, Mutation, Cancer research, biology.protein
وصف الملف: application/pdf