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1دورية أكاديمية
المؤلفون: Michael R. Brandt, Chad E. Beyer, Stephen M. Stahl
المصدر: Pharmaceuticals, Vol 5, Iss 2, Pp 114-132 (2012)
مصطلحات موضوعية: allelic variants, chronic pain, mechanotransduction, neuropathic pain, osteoarthritis, Transient Receptor Potential Vanilloid 1 (TRPV1), Medicine, Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
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2
المؤلفون: Michael R. Brandt, Pascal Bonaventure, Christine Dugovic, William G Bonnette, Lawrence Szewczuk, Ryan M Wyatt, Kristen M. Chevalier, Timothy W. Lovenberg, Brian Lord, Tatiana Koudriakova, Allison White, Ian Fraser, Peter J. Connolly, Kay Ahn, Michelle Wennerholm, Javier Suarez, Sujin Yun, Steven W. Sutton, Brahma Ghosh, Natalie Welty, Leslie Nguyen, Bin Zhu, Sui-Po Zhang, Gaochao Tian, Mark J. Macielag, Michael K. Ameriks, Christopher M. Flores
المصدر: Journal of Pharmacology and Experimental Therapeutics. 372:339-353
مصطلحات موضوعية: Male, 0301 basic medicine, Cannabinoid receptor, Pain, Sleep, REM, Pharmacology, Binding, Competitive, Piperazines, Substrate Specificity, Rats, Sprague-Dawley, Receptor, Cannabinoid, CB2, 03 medical and health sciences, 0302 clinical medicine, Receptor, Cannabinoid, CB1, In vivo, Escherichia coli, Animals, Humans, Enzyme Inhibitors, Receptor, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Brain, Long-term potentiation, Serine hydrolase, Endocannabinoid system, Monoacylglycerol Lipases, Mice, Inbred C57BL, Monoacylglycerol lipase, Kinetics, 030104 developmental biology, Leukocytes, Mononuclear, Molecular Medicine, 030217 neurology & neurosurgery, Endogenous agonist, HeLa Cells, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f425d2e399b62ec058deb114196dce30
https://doi.org/10.1124/jpet.119.262139 -
3
المؤلفون: Ning Qin, Michael F.A. Finley, Christopher M. Flores, Michael P. Neeper, Michael P. Winters, Michael R. Brandt, Wall Mark, Nalin L. Subasinghe, Raymond W. Colburn, Zhihua Sui, Craig R. Schneider, Mary Lou Lubin
المصدر: Bioorganic & Medicinal Chemistry Letters. 28:3780-3783
مصطلحات موضوعية: 010405 organic chemistry, Chemistry, Calcium channel, Organic Chemistry, Clinical Biochemistry, Patch clamp electrophysiology, Cell, Pharmaceutical Science, Pharmacology, N-type calcium channel, 010402 general chemistry, 01 natural sciences, Biochemistry, 0104 chemical sciences, medicine.anatomical_structure, Drug Discovery, Neuropathic pain, medicine, Molecular Medicine, Molecular Biology, Calcium influx
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4
المؤلفون: Kristen M. Chevalier, Sui-Po Zhang, Shu-Chen Lin, Haiyan Bian, Michael R. Brandt, Mark J. Macielag, Li Liu, Cynthia M. Milligan, Christopher M. Flores, Peter J. Connolly, Yue-Mei Zhang, Bin Zhu, Mark McDonnell
المصدر: Bioorganicmedicinal chemistry letters. 30(14)
مصطلحات موضوعية: Models, Molecular, medicine.medical_treatment, Clinical Biochemistry, Azetidine, Pharmaceutical Science, Pharmacology, Crystallography, X-Ray, 01 natural sciences, Biochemistry, Piperazines, chemistry.chemical_compound, Structure-Activity Relationship, Oral administration, Drug Discovery, medicine, Humans, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Endocannabinoid system, Amides, Monoacylglycerol Lipases, 0104 chemical sciences, Monoacylglycerol lipase, 010404 medicinal & biomolecular chemistry, Piperazine, Enzyme, chemistry, Molecular Medicine, Azetidines, Arachidonic acid, Adjuvant
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5
المؤلفون: Mark J, Wall, Nalin L, Subasinghe, Michael P, Winters, Mary Lou, Lubin, Michael F A, Finley, Ning, Qin, Michael R, Brandt, Michael P, Neeper, Craig R, Schneider, Raymond W, Colburn, Christopher M, Flores, Zhihua, Sui
المصدر: Bioorganicmedicinal chemistry letters. 28(23-24)
مصطلحات موضوعية: Male, Analgesics, Patch-Clamp Techniques, Calcium Channel Blockers, Rats, Rats, Sprague-Dawley, Calcium Channels, N-Type, HEK293 Cells, Drug Discovery, Animals, Humans, Neuralgia, Pyrazoles, Calcium, Pyrans
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6
المؤلفون: Scott L. Dax, Mingde Xia, Dennis J. Stone, Xiaoqing Xu, Bin Zhu, Donald William Ludovici, Matthews Jay M, Mark A. Youngman, Tasha L. Hutchinson, Michael R. Brandt, Christopher M. Flores, Mary Lou Lubin, Mark J. Macielag, Raymond W. Colburn, Ning Qin, Manomi A. Tennakoon
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:2234-2237
مصطلحات موضوعية: Clinical Biochemistry, Cell, Glycine, TRPM Cation Channels, Pharmaceutical Science, Stereoisomerism, Pyrimidinones, Pharmacology, Biochemistry, Structure-Activity Relationship, Transient receptor potential channel, In vivo, Drug Discovery, TRPM8, medicine, Animals, Humans, Structure–activity relationship, Molecular Biology, Behavior, Animal, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, In vitro, Rats, HEK293 Cells, medicine.anatomical_structure, Molecular Medicine, Antagonism
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7
المؤلفون: Michael R. Brandt, Michael F.A. Finley, Ning Qin, Michael P. Winters, Craig R. Schneider, Mary Lou Lubin, Michael P. Neeper, Nalin L. Subasinghe, Zhihua Sui, Raymond W. Colburn, Christopher M. Flores, Wall Mark
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:4080-4083
مصطلحات موضوعية: Patch-Clamp Techniques, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, N-type calcium channel, Biochemistry, omega-Conotoxins, Cell Line, Structure-Activity Relationship, Calcium Channels, N-Type, Piperidines, In vivo, Drug Discovery, medicine, Animals, Humans, Potency, Molecular Biology, Analgesics, Ziconotide, Chemistry, Calcium channel, Organic Chemistry, Chronic pain, Metabolic stability, Calcium Channel Blockers, medicine.disease, High-Throughput Screening Assays, Rats, Neuropathic pain, Neuralgia, Pyrazoles, Molecular Medicine, Chronic Pain, medicine.drug
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8
المؤلفون: Ling Lin, Chaozhong Cai, Christopher M. Flores, Timothy P Coogan, Edmund K. LeGrand, Ellen E. Codd, Raymond W. Colburn, Angelique Leone, Charles Y. Wang, Mcdonnell Mark E, Scott L. Dax, Michael R. Brandt, Stewart Bryant, Bart DeCorte, James J. McNally, John R. Mabus, Sui-Po Zhang, John R. Carson, Michael Kemmerer, Dennis J. Stone, James M Lenhard, Michael K. McMillian, Kristen M. Chevalier, Judith Baker
المصدر: Toxicological Sciences. 117:493-504
مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Narcotic Antagonists, medicine.medical_treatment, Cyproheptadine, Cell Enlargement, Pharmacology, Osteochondrodysplasias, Toxicology, Rats, Sprague-Dawley, δ-opioid receptor, Mice, Dogs, Cell Line, Tumor, Insulin-Secreting Cells, Internal medicine, medicine, Animals, Insulin, Potency, Pancreas, chemistry.chemical_classification, Chemistry, High-Throughput Screening Assays, Rats, Diabetes Mellitus, Type 1, Endocrinology, Opioid, Hyperglycemia, Vacuoles, Toxicity, Female, Insulinoma, Serotonin Antagonists, Epiphyses, Hyperglycemic agent, medicine.drug, Tricyclic
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9776c107aa28aa0bdc15b9be77554703
https://doi.org/10.1093/toxsci/kfq200 -
9
المؤلفون: Mary Lou Lubin, Danielle Lawrence, Ning Qin, Yi Liu, Michael R. D'Andrea, Michael R. Brandt, Dennis J. Stone, Yan Wang, Christopher M. Flores, Raymond W. Colburn
المصدر: Neuron. 54(3):379-386
مصطلحات موضوعية: Chemistry, General Neuroscience, Neuroscience(all), Icilin, Sensory system, In vitro, Cell biology, chemistry.chemical_compound, Transient receptor potential channel, In vivo, medicine, TRPM8, Cold sensitivity, medicine.symptom, SYSNEURO, Ion channel
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10
المؤلفون: Geoffrey Hornby, Valerie Smith, Liza Leventhal, Terrance H. Andree, Kathryn Rogers, Michael R. Brandt
المصدر: Journal of Pharmacology and Experimental Therapeutics. 320:1178-1185
مصطلحات موضوعية: Male, Pain Threshold, medicine.medical_specialty, Time Factors, Pain, Mice, Inbred Strains, Pharmacology, Rats, Sprague-Dawley, Mice, Norepinephrine, Cell Line, Tumor, Internal medicine, Desipramine, medicine, Animals, Humans, Fluoxetine, Dose-Response Relationship, Drug, business.industry, Reboxetine, Drug Synergism, Visceral pain, Analgesics, Non-Narcotic, Paroxetine, Rats, Receptors, Adrenergic, Disease Models, Animal, Endocrinology, Receptors, Serotonin, Neuropathic pain, Molecular Medicine, Drug Therapy, Combination, Serotonin, medicine.symptom, Reuptake inhibitor, business, Selective Serotonin Reuptake Inhibitors, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96b491392ef37773dbd6b80e4d0801f
https://doi.org/10.1124/jpet.106.109728