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المؤلفون: Isabelle R. Taylor, Bonnie L. Bassler, Brad R. Henke, Julie S Valastyan, Graham A B Hone, Michael R Tota, Chari D. Smith, Kenneth G Carson, Vasiliki Stergioula
المصدر: ACS Chemical Biology. 15:446-456
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, 010405 organic chemistry, Chemistry, Pseudomonas aeruginosa, Virulence, Biological activity, General Medicine, medicine.disease_cause, 01 natural sciences, Biochemistry, Small molecule, In vitro, 0104 chemical sciences, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Enzyme, Thioesterase, medicine, Molecular Medicine, DNA
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المؤلفون: Julie S, Valastyan, Michael R, Tota, Isabelle R, Taylor, Vasiliki, Stergioula, Graham A B, Hone, Chari D, Smith, Brad R, Henke, Kenneth G, Carson, Bonnie L, Bassler
المصدر: ACS Chem Biol
مصطلحات موضوعية: Small Molecule Libraries, Structure-Activity Relationship, Bacterial Proteins, Molecular Structure, Benzamides, Pseudomonas aeruginosa, Phthalic Acids, DNA, Microbial Sensitivity Tests, Thiolester Hydrolases, Enzyme Inhibitors, Article
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3دورية أكاديمية
المؤلفون: Hua Zhong, John Beaulaurier, Pek Yee Lum, Cliona Molony, Xia Yang, Douglas J Macneil, Drew T Weingarth, Bin Zhang, Danielle Greenawalt, Radu Dobrin, Ke Hao, Sangsoon Woo, Christine Fabre-Suver, Su Qian, Michael R Tota, Mark P Keller, Christina M Kendziorski, Brian S Yandell, Victor Castro, Alan D Attie, Lee M Kaplan, Eric E Schadt
المصدر: PLoS Genetics, Vol 6, Iss 5, p e1000932 (2010)
وصف الملف: electronic resource
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المؤلفون: Jan Karolin, Chris D. Geddes, Michael R. Tota, Jeanna M. Allen, William W. Ward
المصدر: Photochemistry and Photobiology. 92:667-677
مصطلحات موضوعية: 0301 basic medicine, Absorption (pharmacology), Yellow fluorescent protein, Scyphozoa, biology, Analytical chemistry, Quantum yield, General Medicine, Rhacostoma, Chromophore, Molar absorptivity, Biochemistry, Fluorescence, Luminescent Proteins, 03 medical and health sciences, 030104 developmental biology, biology.protein, Biophysics, Animals, Cloning, Molecular, Physical and Theoretical Chemistry, Peptide sequence
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المؤلفون: Stefan Krauss, Michael R. Tota, Nicole Ginanni, Margaret Wu, Peter Strack, Nancy E. Kohl, Nathan Bays, Victoria M. Richon, Eric Bachman, Yanai Zhan
المصدر: Clinical Cancer Research. 14:5735-5742
مصطلحات موضوعية: Cancer Research, Cell Survival, Biology, Transfection, Cell Line, chemistry.chemical_compound, Acetyltransferases, Humans, Enzyme Inhibitors, Fatty acid synthesis, Cell Proliferation, Cell growth, Lipogenesis, HCT116 Cells, Oncology, Biochemistry, chemistry, Apoptosis, Cell culture, Colonic Neoplasms, Cancer cell, Cancer research, Fatty Acid Synthases, Signal transduction, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452835503093428fee32a680e78792bc
https://doi.org/10.1158/1078-0432.ccr-07-5074 -
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المؤلفون: Michael R. Tota, Su Qian, Peter Nizner, Sheena Mumick, Joseph Menetski, Marc L. Reitman, Douglas J. MacNeil
المصدر: Basic & Clinical Pharmacology & Toxicology. 103:36-42
مصطلحات موضوعية: Male, medicine.medical_specialty, Genotype, Glutathione reductase, Malic enzyme, Biology, Toxicology, Malate dehydrogenase, Mice, chemistry.chemical_compound, Cytosol, Malate Dehydrogenase, Internal medicine, medicine, Animals, Glycolysis, Acetaminophen, Pharmacology, Liver injury, Analgesics, General Medicine, Glutathione, medicine.disease, Mice, Mutant Strains, Mice, Inbred C57BL, Citric acid cycle, Endocrinology, Liver, Biochemistry, chemistry, Chemical and Drug Induced Liver Injury, NADP, Nicotinamide adenine dinucleotide phosphate
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المؤلفون: Michael J. Forrest, Matthew J. Wyvratt, Lex H.T. Van der Ploeg, Kajal Patel, Michael H. Fisher, Ann E. Weber, Jiafang He, Anthony Mastracchio, Emma R. Parmee, Michael R. Tota, Euan Macintyre, Scott D. Edmondson, Xinchun Tong, Naphtali A. O'Connor, Joseph M. Metzger, Jeff P. Varnerin, Christine C. Chung, Scott Hofsess
المصدر: Bioorganic & Medicinal Chemistry Letters. 13:3983-3987
مصطلحات موضوعية: Vinyl Compounds, Phosphodiesterase Inhibitors, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Amide, Drug Discovery, Molecular Biology, chemistry.chemical_classification, biology, Organic Chemistry, Cyclic Nucleotide Phosphodiesterases, Type 3, In vitro, Pyridazines, Kinetics, Enzyme, chemistry, 3',5'-Cyclic-AMP Phosphodiesterases, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Selectivity, Enone
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المؤلفون: Christopher P. Austin, Doreen E. Cashen, Sheng-Shung Pong, Brian D. Spar, Brett Connolly, Tung Ming Fong, D. Euan MacIntyre, Carina P. Tan, Michael R. Tota, Ravi P. Nargund, R. S. L. Chang, Oksana C. Palyha, Constantin Tamvakopoulos, Deborah L. Drazen, Anthony G. DiLella, Jennifer E. Drisko, David J. Figueroa, Tanya MacNeil, Andreas W. Sailer, David H. Weinberg, Randy J. Nelson, Charles Rosenblum, Cathy R.-R.C. Huang, Rui Tang, Arthur A. Patchett, Xiao-Ming Guan, Hong Yu, George J. Christ, Andrew D. Howard, Lex H.T. Van der Ploeg, William J. Martin, Aurawan Vongs, Iyassu K. Sebhat, Ralph A. Stearns
المصدر: Proceedings of the National Academy of Sciences. 99:11381-11386
مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, DNA, Complementary, Intracranial Pressure, medicine.drug_class, Blood Pressure, In Vitro Techniques, Biology, Somatosensory system, Mice, Sexual Behavior, Animal, Nerve Fibers, Internal medicine, Copulation, medicine, Animals, Glans, In Situ Hybridization, DNA Primers, Multidisciplinary, Reverse Transcriptase Polymerase Chain Reaction, Human penis, Feeding Behavior, Ribonuclease, Pancreatic, Biological Sciences, Spinal cord, Electric Stimulation, Mice, Inbred C57BL, Melanocortin 4 receptor, medicine.anatomical_structure, Endocrinology, Receptors, Corticotropin, Models, Animal, Receptor, Melanocortin, Type 4, Brainstem, Energy Metabolism, Penis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341db11f0e12a0307d07e04176cd4aad
https://doi.org/10.1073/pnas.172378699 -
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المؤلفون: L. H. T. Van Der Ploeg, Michael R. Tota, K. K. Wu, Ramon E. Camacho, T. M. Fong, Chun-Pyn Shen, Lauren P. Shearman
المصدر: Journal of Neuroendocrinology. 14:607-610
مصطلحات موضوعية: medicine.medical_specialty, Meal, Endocrine and Autonomic Systems, Chemistry, Endocrinology, Diabetes and Metabolism, Leptin, digestive, oral, and skin physiology, Cellular and Molecular Neuroscience, Endocrinology, nervous system, Fasted state, Internal medicine, Plasma concentration, medicine, Ingestion, hormones, hormone substitutes, and hormone antagonists, Agouti-Related Protein, Federal state
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المؤلفون: Michael R. Tota, Ravi P. Nargund, Xiao-Ming Guan, Howard Y. Chen, Douglas J. MacNeil, David H. Weinberg, Tanya MacNeil, Euan Macintyre, Alison M. Strack, Charles Rosenblum, Maria A. Bednarek, Andrew D. Howard, Chun-Pyn Shen, Tung M. Fong, Mark T. Goulet, Lex H.T. Van der Ploeg, Airu S. Chen, Donald J. Marsh
المصدر: European Journal of Pharmacology. 440:141-157
مصطلحات موضوعية: endocrine system, medicine.medical_specialty, Gene Expression, Biology, Melanocortin receptor, Proopiomelanocortin, Internal medicine, medicine, Animals, Humans, Melanocyte-Stimulating Hormones, Obesity, Receptor, Melanocortins, Pharmacology, integumentary system, Receptors, Melanocortin, digestive, oral, and skin physiology, Body Weight, Melanocortin 3 receptor, Melanocortin 4 receptor, Endocrinology, Receptors, Corticotropin, biology.protein, Anti-Obesity Agents, Melanocortin, hormones, hormone substitutes, and hormone antagonists, Melanocortin 1 receptor