نتائج البحث - "Michael Surace"

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دورية أكاديمية

The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment

المؤلفون: Elizabeth L. Hardaker, Emilio Sanseviero, Ankur Karmokar, Devon Taylor, Marta Milo, Chrysis Michaloglou, Adina Hughes, Mimi Mai, Matthew King, Anisha Solanki, Lukasz Magiera, Ricardo Miragaia, Gozde Kar, Nathan Standifer, Michael Surace, Shaan Gill, Alison Peter, Sara Talbot, Sehmus Tohumeken, Henderson Fryer, Ali Mostafa, Kathy Mulgrew, Carolyn Lam, Scott Hoffmann, Daniel Sutton, Larissa Carnevalli, Fernando J. Calero-Nieto, Gemma N. Jones, Andrew J. Pierce, Zena Wilson, David Campbell, Lynet Nyoni, Carla P. Martins, Tamara Baker, Gilberto Serrano de Almeida, Zainab Ramlaoui, Abdel Bidar, Benjamin Phillips, Joseph Boland, Sonia Iyer, J. Carl Barrett, Arsene-Bienvenu Loembé, Serge Y. Fuchs, Umamaheswar Duvvuri, Pei-Jen Lou, Melonie A. Nance, Carlos Alberto Gomez Roca, Elaine Cadogan, Susan E. Critichlow, Steven Fawell, Mark Cobbold, Emma Dean, Viia Valge-Archer, Alan Lau, Dmitry I. Gabrilovich, Simon T. Barry

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/189773f2417346dcbdf8b6281d57effa

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دورية أكاديمية

1505 Spatial profiling of the SCLC tumor microenvironment defined by high MHC-I expression reveals association with functionally relevant antigen presentation

المؤلفون: Guenter Schmidt, Nicolas Brieu, Harald Hessel, Andreas Spitzmüller, Jaime Rodriguez Canales, Helen Angell, Markus Schick, Mingchao Xie, Mari Heininen-Brown, Miljenka Vuko, Monica Azqueta Gavaldon, Felix Segerer, Marco Testori, Michael Surace, Shashank Saran, Hadassah Sade, J Carl Barrett, Giulia Fabbri, Alma Andoni

المصدر: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-1426

URL الوصول: https://doaj.org/article/7c5f992f1f3d413b93f89f92865f3373

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3

دورية أكاديمية

Automated Multiplex Immunofluorescence Panel for Immuno-oncology Studies on Formalin-fixed Carcinoma Tissue Specimens

المؤلفون: Michael Surace, author¹, Karma DaCosta, author¹, Anna Huntley, author¹, Weiguang Zhao, author¹, Christopher Bagnall, author², Charles Brown, author¹, Chichung Wang, author³, Kristin Roman, author³, Jennifer Cann, author¹, Arthur Lewis, author², Keith Steele, author¹, Marlon Rebelatto, author¹, Edwin R. Parra, author⁴, Clifford C. Hoyt, author³, Jaime Rodriguez-Canales, author¹

المصدر: Journal of Visualized Experiments. (143)

الإتاحة: http://www.jove.com/video/58390

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155 MHC class I antigen presentation is associated with an inflamed SCLC tumor microenvironment characterized by a higher density of cytotoxic T-cells in closer proximity to tumor cells

المؤلفون: Miljenka Vuko, Mingchao Xie, Monica Azqueta Gavaldon, Felix Segerer, Andreas Spitzmüller, Harald Hessel, Marco Testori, Johannes Zimmermann, Michael Surace, Mari Heininen-Brown, Jaime Rodriguez Canales, Shashank Saran, Helen Angell, Guenter Schmidt, Hadassah Sade, J Carl Barrett, Markus Schick, Giulia Fabbri

المصدر: Regular and Young Investigator Award Abstracts.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5ee4d786cda7f0934e98c15471b7d828
https://doi.org/10.1136/jitc-2022-sitc2022.0155

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Abstract CT198: Immunomodulatory effects of the ATR inhibitor ceralasertib in a window of opportunity biomarker trial in patients with head and neck squamous cell carcinoma

المصدر: Cancer Research. 83:CT198-CT198

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1ef60f9526118564cdedf59100e51929
https://doi.org/10.1158/1538-7445.am2023-ct198

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An Unsupervised Graph Embeddings Approach to Multiplex Immunofluorescence Image Exploration

المؤلفون: Isabelle Gaffney, Cohen-Setton J, Zhenning Zhang, Dillon Lal, Jason Hipp, Christopher Innocenti, Frangos M, Carlos Pedrinaci, Michael Surace, Balaji Selvaraj, Khan Baykaner

مصطلحات موضوعية: User Friendly, business.industry, Deep learning, Machine learning, computer.software_genre, Pipeline (software), Image (mathematics), Unsupervised learning, Graph (abstract data type), Leverage (statistics), Artificial intelligence, Cluster analysis, business, computer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bf9f09a6793df73022148c339c03429b
https://doi.org/10.1101/2021.06.09.447654

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Abstract 1711: A multi-modal analysis approach leveraging multiplexed spatial phenotyping and multi-omics analysis to better understand the prognostic value of tertiary lymphoid structures in non-small cell lung cancer

المؤلفون: Julie Berthe, Felix Segerer, Emily C. Jennings, Alma Andoni, Marco Testori, Megha Saraiya, Miljenka Vuko, Harald Hessel, Andreas Spitzmüller, Mari Heininen-Brown, Jorge Blando, Felicia Ng, Emma Jones, Sophie Willis, Michael Surace, Rieneke van de Ven, Tanja De Gruijl, Helen Angell

المصدر: Cancer Research. 82:1711-1711

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::121cd5909ffbbf9674e188da12b3ffa1
https://doi.org/10.1158/1538-7445.am2022-1711

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Abstract 1235: Presence of TLS and combined high densities of PD-L1+ macrophages & CD8+ T cells predict long-term overall survival for patients with advanced NSCLC treated with durvalumab

المؤلفون: Lina Meinecke, Jorge Blando, Thomas Herz, Michael Surace, Thomas Padel, Monica Azqueta Gavaldon, Harald Hessel, Farzad Sekhavati, Megha Saraiya, Anmarie Boutrin, Karma Da Costa, Jaime Rodriguez Canales, Ashok Gupta, Carl Barrett, Zachary Aaron Cooper, Ikbel Achour

المصدر: Cancer Research. 82:1235-1235

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4ca19cfc8a712cc85ff7e165a5faeafe
https://doi.org/10.1158/1538-7445.am2022-1235

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39 A multi-modal analysis approach leveraging multiplexed spatial phenotyping and multi-omics analysis to better understand the prognostic value of tertiary lymphoid structures in NSCLC

المؤلفون: Rieneke van de Ven, Sophie E. Willis, Marco Testori, Megha Saraiya, Michael Surace, Harald Hessel, Mari Heininen-Brown, Tanja D. de Gruijl, Sriram Sridhar, Felix Segerer, Emma Jones, Lorenz Rognoni, Anatoliy Shumilov, Jorge Blando, Andreas Spitzmüller, Julie Berthe, Helen K. Angell, Felicia S.L. Ng, Alma Andoni

المصدر: Journal for ImmunoTherapy of Cancer. 9:A46-A46

مصطلحات موضوعية: Pharmacology, Cancer Research, Oncology, Tertiary Lymphoid Structures, Computer science, Modal analysis, Immunology, Molecular Medicine, Immunology and Allergy, Multi omics, Computational biology, Value (mathematics), Multiplexing

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3ff070184cb222021f8f2eb2d7b1b5bc
https://doi.org/10.1136/jitc-2021-sitc2021.039

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822 GraphITE: unsupervised graph embeddings approach to multiplex immunofluorescence image exploration reveals new insights into NSCLC and HNSCC tumor microenvironment

المؤلفون: Christopher Innocenti, Andreas Spitzmüller, Zhenning Zhang, Isabelle Gaffney, Michael Surace, Balaji Selvaraj, Helen K. Angell, Khan Baykaner

المصدر: Journal for ImmunoTherapy of Cancer. 9:A860-A860

مصطلحات موضوعية: Pharmacology, Cancer Research, Tumor microenvironment, medicine.diagnostic_test, Computer science, Immunology, Computational biology, Immunofluorescence, Image (mathematics), Oncology, medicine, Molecular Medicine, Immunology and Allergy, Graph (abstract data type), Multiplex

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4b9d9d3010c82fadea740010c34b6456
https://doi.org/10.1136/jitc-2021-sitc2021.822

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